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Items: 1 to 50 of 275

1.

Linker engineering in anti-TAG-72 antibody fragments optimizes biophysical properties, serum half-life, and high-specificity tumor imaging.

Long NE, Sullivan BJ, Ding H, Doll S, Ryan MA, Hitchcock CL, Martin EW Jr, Kumar K, Tweedle MF, Magliery TJ.

J Biol Chem. 2018 Jun 8;293(23):9030-9040. doi: 10.1074/jbc.RA118.002538. Epub 2018 Apr 18.

PMID:
29669811
2.

Relationship of Sequence and Phase Separation in Protein Low-Complexity Regions.

Martin EW, Mittag T.

Biochemistry. 2018 May 1;57(17):2478-2487. doi: 10.1021/acs.biochem.8b00008. Epub 2018 Mar 16.

PMID:
29517898
3.

A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing.

Wang A, Conicella AE, Schmidt HB, Martin EW, Rhoads SN, Reeb AN, Nourse A, Ramirez Montero D, Ryan VH, Rohatgi R, Shewmaker F, Naik MT, Mittag T, Ayala YM, Fawzi NL.

EMBO J. 2018 Mar 1;37(5). pii: e97452. doi: 10.15252/embj.201797452. Epub 2018 Feb 9.

4.

Antigen-Directed Cancer Surgery for Primary Colorectal Cancer: 15-Year Survival Analysis: A Reply.

Povoski SP, Hatzaras IS, Mojzisik CM, Arnold MW, Hitchcock CL, Martin EW Jr.

Ann Surg Oncol. 2017 Dec;24(Suppl 3):610-611. doi: 10.1245/s10434-017-6201-z. Epub 2017 Oct 30. No abstract available.

PMID:
29086138
5.

A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer.

Robertson RM, Yao J, Gajewski S, Kumar G, Martin EW, Rock CO, White SW.

Nat Struct Mol Biol. 2017 Aug;24(8):666-671. doi: 10.1038/nsmb.3436. Epub 2017 Jul 17.

6.

A 3E8.scFv.Cys-IR800 Conjugate Targeting TAG-72 in an Orthotopic Colorectal Cancer Model.

Gong L, Ding H, Long NE, Sullivan BJ, Martin EW Jr, Magliery TJ, Tweedle MF.

Mol Imaging Biol. 2018 Feb;20(1):47-54. doi: 10.1007/s11307-017-1096-4.

7.

Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.

Buzza MS, Johnson TA, Conway GD, Martin EW, Mukhopadhyay S, Shea-Donohue T, Antalis TM.

J Biol Chem. 2017 Jun 30;292(26):10801-10812. doi: 10.1074/jbc.M116.771469. Epub 2017 May 10.

8.

Dynamic biochemical tissue analysis detects functional L-selectin ligands on colon cancer tissues.

Carlson GE, Martin EW, Shirure VS, Malgor R, Resto VA, Goetz DJ, Burdick MM.

PLoS One. 2017 Mar 10;12(3):e0173747. doi: 10.1371/journal.pone.0173747. eCollection 2017.

9.

Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation.

Martin EW, Holehouse AS, Grace CR, Hughes A, Pappu RV, Mittag T.

J Am Chem Soc. 2016 Nov 30;138(47):15323-15335. Epub 2016 Nov 17.

10.

Palliative Care-Led Meetings for Families of ICU Patients.

Martin EW.

JAMA. 2016 Oct 18;316(15):1598. doi: 10.1001/jama.2016.14319. No abstract available.

PMID:
27755630
11.

A Wearable Goggle Navigation System for Dual-Mode Optical and Ultrasound Localization of Suspicious Lesions: Validation Studies Using Tissue-Simulating Phantoms and an Ex Vivo Human Breast Tissue Model.

Zhang Z, Pei J, Wang D, Gan Q, Ye J, Yue J, Wang B, Povoski SP, Martin EW Jr, Hitchcock CL, Yilmaz A, Tweedle MF, Shao P, Xu RX.

PLoS One. 2016 Jul 1;11(7):e0157854. doi: 10.1371/journal.pone.0157854. eCollection 2016.

12.

Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells.

Ugarte F, Sousae R, Cinquin B, Martin EW, Krietsch J, Sanchez G, Inman M, Tsang H, Warr M, Passegué E, Larabell CA, Forsberg EC.

Stem Cell Reports. 2015 Nov 10;5(5):728-740. doi: 10.1016/j.stemcr.2015.09.009. Epub 2015 Oct 17.

13.

Extracting Infrared Spectra of Protein Secondary Structures Using a Library of Protein Spectra and the Ramachandran Plot.

Coe JV, Nystrom SV, Chen Z, Li R, Verreault D, Hitchcock CL, Martin EW Jr, Allen HC.

J Phys Chem B. 2015 Oct 15;119(41):13079-92. doi: 10.1021/acs.jpcb.5b08052. Epub 2015 Sep 30.

PMID:
26397941
14.

Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden.

Martin EW, Buzza MS, Driesbaugh KH, Liu S, Fortenberry YM, Leppla SH, Antalis TM.

Oncotarget. 2015 Oct 20;6(32):33534-53. doi: 10.18632/oncotarget.5214.

15.

Intraoperative Use of a Portable Large Field of View Gamma Camera and Handheld Gamma Detection Probe for Radioguided Localization and Prediction of Complete Surgical Resection of Gastrinoma: Proof of Concept.

Hall NC, Nichols SD, Povoski SP, James IA, Wright CL, Harris R, Schmidt CR, Muscarella P 2nd, Latchana N, Martin EW Jr, Ellison EC.

J Am Coll Surg. 2015 Aug;221(2):300-8. doi: 10.1016/j.jamcollsurg.2015.03.047. Epub 2015 Apr 1.

PMID:
26206636
16.

Feasibility of a multimodal (18)F-FDG-directed lymph node surgical excisional biopsy approach for appropriate diagnostic tissue sampling in patients with suspected lymphoma.

Povoski SP, Hall NC, Murrey DA Jr, Wright CL, Martin EW Jr.

BMC Cancer. 2015 May 8;15:378. doi: 10.1186/s12885-015-1381-z.

17.

Co-encapsulating the fusogenic peptide INF7 and molecular imaging probes in liposomes increases intracellular signal and probe retention.

Burks SR, Legenzov EA, Martin EW, Li C, Lu W, Kao JP.

PLoS One. 2015 Mar 27;10(3):e0120982. doi: 10.1371/journal.pone.0120982. eCollection 2015.

18.

Intraoperative scintigraphy using a large field-of-view portable gamma camera for primary hyperparathyroidism: initial experience.

Hall NC, Plews RL, Agrawal A, Povoski SP, Wright CL, Zhang J, Martin EW Jr, Phay J.

Biomed Res Int. 2015;2015:930575. doi: 10.1155/2015/930575. Epub 2015 Jan 6.

19.

Ex vivo electrical impedance measurements on excised hepatic tissue from human patients with metastatic colorectal cancer.

Prakash S, Karnes MP, Sequin EK, West JD, Hitchcock CL, Nichols SD, Bloomston M, Abdel-Misih SR, Schmidt CR, Martin EW Jr, Povoski SP, Subramaniam VV.

Physiol Meas. 2015 Feb;36(2):315-28. doi: 10.1088/0967-3334/36/2/315. Epub 2015 Jan 19.

PMID:
25597963
20.

Complex chronic conditions in Rhode Island's pediatric populace: implications for palliative and hospice services, 2000-2012.

Jamorabo DS, Belani CP, Martin EW.

J Palliat Med. 2015 Apr;18(4):350-7. doi: 10.1089/jpm.2014.0226. Epub 2014 Dec 18.

PMID:
25522161
21.

Proteolytic activation of the protease-activated receptor (PAR)-2 by the glycosylphosphatidylinositol-anchored serine protease testisin.

Driesbaugh KH, Buzza MS, Martin EW, Conway GD, Kao JP, Antalis TM.

J Biol Chem. 2015 Feb 6;290(6):3529-41. doi: 10.1074/jbc.M114.628560. Epub 2014 Dec 17.

24.

Origins of electronic band gap reduction in Cr/N codoped TiO2.

Parks Cheney C, Vilmercati P, Martin EW, Chiodi M, Gavioli L, Regmi M, Eres G, Callcott TA, Weitering HH, Mannella N.

Phys Rev Lett. 2014 Jan 24;112(3):036404. Epub 2014 Jan 23.

PMID:
24484152
25.

Isolation and characterization of chimeric human Fc-expressing proteins using protein a membrane adsorbers and a streamlined workflow.

Burdick MM, Reynolds NM, Martin EW, Hawes JV, Carlson GE, Cuckler CM, Bates MC, Barthel SR, Dimitroff CJ.

J Vis Exp. 2014 Jan 8;(83):e51023. doi: 10.3791/51023.

26.
27.

Site specific discrete PEGylation of (124)I-labeled mCC49 Fab' fragments improves tumor MicroPET/CT imaging in mice.

Ding H, Carlton MM, Povoski SP, Milum K, Kumar K, Kothandaraman S, Hinkle GH, Colcher D, Brody R, Davis PD, Pokora A, Phelps M, Martin EW Jr, Tweedle MF.

Bioconjug Chem. 2013 Nov 20;24(11):1945-54. doi: 10.1021/bc400375f. Epub 2013 Oct 31.

28.

A multifaceted intervention to improve compliance with process measures for ICU clinician communication with ICU patients and families.

Black MD, Vigorito MC, Curtis JR, Phillips GS, Martin EW, McNicoll L, Rochon T, Ross S, Levy MM.

Crit Care Med. 2013 Oct;41(10):2275-83. doi: 10.1097/CCM.0b013e3182982671.

PMID:
24060769
29.
30.

Infrared metrics for fixation-free liver tumor detection.

Chen Z, Butke R, Miller B, Hitchcock CL, Allen HC, Povoski SP, Martin EW Jr, Coe JV.

J Phys Chem B. 2013 Oct 17;117(41):12442-50. doi: 10.1021/jp4073087. Epub 2013 Oct 7.

31.

Pain, depression, and fatigue: loneliness as a longitudinal risk factor.

Jaremka LM, Andridge RR, Fagundes CP, Alfano CM, Povoski SP, Lipari AM, Agnese DM, Arnold MW, Farrar WB, Yee LD, Carson WE 3rd, Bekaii-Saab T, Martin EW Jr, Schmidt CR, Kiecolt-Glaser JK.

Health Psychol. 2014 Sep;33(9):948-57. doi: 10.1037/a0034012. Epub 2013 Aug 19.

32.

Low dose hard x-ray contact microscopy assisted by a photoelectric conversion layer.

Gomella A, Martin EW, Lynch SK, Morgan NY, Wen H.

AIP Adv. 2013 Apr 18;3(4):42121. Print 2013 Apr.

33.

Single molecular weight discrete PEG compounds: emerging roles in molecular diagnostics, imaging and therapeutics.

Povoski SP, Davis PD, Colcher D, Martin EW Jr.

Expert Rev Mol Diagn. 2013 May;13(4):315-9. doi: 10.1586/erm.13.19. No abstract available.

34.
35.

Use of intraoperative nuclear medicine imaging technology: strategy for improved patient management.

Hall NC, Povoski SP, Zhang J, Knopp MV, Martin EW Jr.

Expert Rev Med Devices. 2013 Mar;10(2):149-52. doi: 10.1586/erd.13.2. No abstract available.

PMID:
23480081
36.

Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.

Buzza MS, Martin EW, Driesbaugh KH, Désilets A, Leduc R, Antalis TM.

J Biol Chem. 2013 Apr 12;288(15):10328-37. doi: 10.1074/jbc.M112.443432. Epub 2013 Feb 26.

37.

Image-guided technologies to facilitate the dissection of microsurgical autologous tissue-free flaps.

Kocak E, Carruthers KH, Knopp MV, Carkaci S, Martin EW Jr, Povoski SP.

Expert Rev Med Devices. 2012 Nov;9(6):547-9. doi: 10.1586/erd.12.61. Review. No abstract available.

PMID:
23249148
38.

Mathematical model of colitis-associated colon cancer.

Lo WC, Martin EW Jr, Hitchcock CL, Friedman A.

J Theor Biol. 2013 Jan 21;317:20-9. doi: 10.1016/j.jtbi.2012.09.025. Epub 2012 Sep 28.

PMID:
23026764
39.

Reconstruction of total pelvic exenteration defects with rectus abdominus myocutaneous flaps versus primary closure.

Chokshi RJ, Kuhrt MP, Arrese D, Martin EW Jr.

Am J Surg. 2013 Jan;205(1):64-70. doi: 10.1016/j.amjsurg.2012.04.010. Epub 2012 Jul 30.

PMID:
22854008
40.

Retrospective review of pelvic malignancies undergoing total pelvic exenteration.

Kuhrt MP, Chokshi RJ, Arrese D, Martin EW Jr.

World J Surg Oncol. 2012 Jun 15;10:110. doi: 10.1186/1477-7819-10-110.

41.

Cytopathologic evaluation of the in situ margin in patients undergoing hepatectomy.

Jones NB, Wakely PE Jr, Klemanski DL, Al-Saif O, Young G, Frankel WL, Martin EW, Bloomston M.

Cancer Cytopathol. 2012 Dec 25;120(6):410-5. doi: 10.1002/cncy.21204. Epub 2012 May 17.

42.

Multimodal imaging and detection strategy with 124 I-labeled chimeric monoclonal antibody cG250 for accurate localization and confirmation of extent of disease during laparoscopic and open surgical resection of clear cell renal cell carcinoma.

Povoski SP, Hall NC, Murrey DA Jr, Sharp DS, Hitchcock CL, Mojzisik CM, Bahnson EE, Knopp MV, Martin EW Jr, Bahnson RR.

Surg Innov. 2013 Feb;20(1):59-69. doi: 10.1177/1553350612438416. Epub 2012 Mar 27.

43.

A single-institution approach to total pelvic exenteration.

Chokshi RJ, Fowler J, Cohn D, Bahnson R, Lumbley J, Martin EW Jr.

Am Surg. 2011 Dec;77(12):1629-39.

PMID:
22273221
44.

Repeat hepatectomy for metastatic colorectal cancer is safe but marginally effective.

Jones NB, McNally ME, Malhotra L, Abdel-Misih S, Martin EW, Bloomston M, Schmidt CR.

Ann Surg Oncol. 2012 Jul;19(7):2224-9. doi: 10.1245/s10434-011-2179-0. Epub 2011 Dec 30.

PMID:
22207046
45.

Multimodal imaging and detection approach to 18F-FDG-directed surgery for patients with known or suspected malignancies: a comprehensive description of the specific methodology utilized in a single-institution cumulative retrospective experience.

Povoski SP, Hall NC, Murrey DA Jr, Chow AZ, Gaglani JR, Bahnson EE, Mojzisik CM, Kuhrt MP, Hitchcock CL, Knopp MV, Martin EW Jr.

World J Surg Oncol. 2011 Nov 23;9:152. doi: 10.1186/1477-7819-9-152.

46.

Oncologic theranostics: recognition of this concept in antigen-directed cancer therapy for colorectal cancer with anti-TAG-72 monoclonal antibodies.

Povoski SP, Hatzaras IS, Mojzisik CM, Martin EW Jr.

Expert Rev Mol Diagn. 2011 Sep;11(7):667-70. doi: 10.1586/erm.11.54. No abstract available.

PMID:
21902525
47.

Single institution experience comparing double-barreled wet colostomy to ileal conduit for urinary and fecal diversion.

Chokshi RJ, Kuhrt MP, Schmidt C, Arrese D, Routt M, Parks L, Bahnson R, Martin EW Jr.

Urology. 2011 Oct;78(4):856-62. doi: 10.1016/j.urology.2011.06.030. Epub 2011 Aug 31.

PMID:
21885094
48.

Antigen-directed cancer surgery for primary colorectal cancer: 15-year survival analysis.

Povoski SP, Hatzaras IS, Mojzisik CM, Arnold MW, Hinkle GH, Hitchcock CL, Young DC, Martin EW Jr.

Ann Surg Oncol. 2012 Jan;19(1):131-8. doi: 10.1245/s10434-011-1880-3. Epub 2011 Jul 6.

PMID:
21732140
49.

Turning the attentional blink on and off: opposing effects of spatial and temporal noise.

Martin EW, Enns JT, Shapiro KL.

Psychon Bull Rev. 2011 Apr;18(2):295-301. doi: 10.3758/s13423-011-0056-2.

PMID:
21336681
50.

124I-HuCC49deltaCH2 for TAG-72 antigen-directed positron emission tomography (PET) imaging of LS174T colon adenocarcinoma tumor implants in xenograft mice: preliminary results.

Zou P, Povoski SP, Hall NC, Carlton MM, Hinkle GH, Xu RX, Mojzisik CM, Johnson MA, Knopp MV, Martin EW Jr, Sun D.

World J Surg Oncol. 2010 Aug 6;8:65. doi: 10.1186/1477-7819-8-65.

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