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Items: 1 to 50 of 161

1.

Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets.

Enoksson M, Martin EJ, Holmberg H, Jensen MS, Kjelgaard-Hansen M, Egebjerg T, Buchardt J, Krogh TN, Demuth H, Sanfridson A, Hilden I, Kjalke M, Brophy DF.

J Thromb Haemost. 2019 Sep 23. doi: 10.1111/jth.14644. [Epub ahead of print]

PMID:
31549480
2.

All-Assay-Max2 pQSAR: Activity Predictions as Accurate as Four-Concentration IC50s for 8558 Novartis Assays.

Martin EJ, Polyakov VR, Zhu XW, Tian L, Mukherjee P, Liu X.

J Chem Inf Model. 2019 Oct 28;59(10):4450-4459. doi: 10.1021/acs.jcim.9b00375. Epub 2019 Sep 26.

PMID:
31518124
3.

A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.

Al-Horani RA, Abdelfadiel EI, Afosah DK, Morla S, Sistla JC, Mohammed B, Martin EJ, Sakagami M, Brophy DF, Desai UR.

J Thromb Haemost. 2019 Dec;17(12):2110-2122. doi: 10.1111/jth.14606. Epub 2019 Sep 10.

PMID:
31397071
4.

Characterizing Palliative Radiotherapy Education in Hospice and Palliative Medicine Fellowship: A Survey of Fellowship Program Directors.

Martin EJ, Jones JA.

J Palliat Med. 2019 Aug 2. doi: 10.1089/jpm.2019.0119. [Epub ahead of print]

PMID:
31373879
5.

Palliative Radiotherapy Education for Hospice and Palliative Medicine Fellows: A National Needs Assessment.

Martin EJ, Jones JA.

J Palliat Med. 2019 Aug 2. doi: 10.1089/jpm.2019.0118. [Epub ahead of print]

PMID:
31373870
6.

Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas.

Patel-Hett S, Martin EJ, Mohammed BM, Rakhe S, Sun P, Barrett JC, Nolte ME, Kuhn J, Pittman DD, Murphy JE, Brophy DF.

Haemophilia. 2019 Sep;25(5):797-806. doi: 10.1111/hae.13820. Epub 2019 Jul 23.

PMID:
31336410
7.

Temporal map of the pig polytrauma plasma proteome with fluid resuscitation and intravenous vitamin C treatment.

Cudjoe EK Jr, Hassan ZH, Kang L, Reynolds PS, Fisher BJ, McCarter J, Sweeney C, Martin EJ, Middleton P, Ellenberg M, Fowler AA 3rd, Spiess BD, Brophy DF, Hawkridge AM, Natarajan R.

J Thromb Haemost. 2019 Nov;17(11):1827-1837. doi: 10.1111/jth.14580. Epub 2019 Aug 25.

PMID:
31322812
8.

Incorporating palliative radiotherapy education into hospice and palliative medicine fellowship training: a feasibility study.

Martin EJ, Nalawade VV, Murphy JD, Jones JA.

Ann Palliat Med. 2019 Sep;8(4):436-441. doi: 10.21037/apm.2019.04.02. Epub 2019 May 1.

9.

Effects of a novel low volume resuscitation solutions on coagulation and platelet function.

Liebrecht LK, Newton J, Martin EJ, Wickramaratne N, Jayaraman S, Han J, Aboutanos M, Brophy DF, Mangino MJ.

PLoS One. 2019 May 1;14(5):e0215386. doi: 10.1371/journal.pone.0215386. eCollection 2019.

10.

Communication skill frameworks: applications in radiation oncology.

Martin EJ, Rich SE, Jones JA, Dharmarajan KV.

Ann Palliat Med. 2019 Jul;8(3):293-304. doi: 10.21037/apm.2019.03.03. Epub 2019 Mar 25.

11.

Bearing Witness and Finding Meaning.

Martin EJ.

JAMA. 2019 Mar 19;321(11):1051-1052. doi: 10.1001/jama.2019.1292. No abstract available.

PMID:
30874759
12.

Platelets retain inducible alpha granule secretion by P-selectin expression but exhibit mechanical dysfunction during trauma-induced coagulopathy.

St John AE, Newton JC, Martin EJ, Mohammed BM, Contaifer D Jr, Saunders JL, Brophy GM, Spiess BD, Ward KR, Brophy DF, López JA, White NJ.

J Thromb Haemost. 2019 May;17(5):771-781. doi: 10.1111/jth.14414. Epub 2019 Mar 18.

PMID:
30784176
13.

Use of global assays to monitor emicizumab prophylactic therapy in patients with haemophilia A with inhibitors.

Brophy DF, Martin EJ, Kuhn J.

Haemophilia. 2019 Mar;25(2):e121-e123. doi: 10.1111/hae.13689. Epub 2019 Feb 12. No abstract available.

PMID:
30748061
14.

Thromboelastographic analysis of novel polyethylene glycol based low volume resuscitation solutions.

Liebrecht LK, Newton J, Martin EJ, Wickramaratne N, Jayaraman S, Han J, Aboutanos M, Brophy DF, Mangino MJ.

PLoS One. 2018 Nov 15;13(11):e0207147. doi: 10.1371/journal.pone.0207147. eCollection 2018.

15.

Informing efficient pilot development of animal trauma models through quality improvement strategies.

Reynolds PS, McCarter J, Sweeney C, Mohammed BM, Brophy DF, Fisher B, Martin EJ, Natarajan R.

Lab Anim. 2019 Aug;53(4):394-404. doi: 10.1177/0023677218802999. Epub 2018 Oct 9.

PMID:
30296892
16.

Evaluating the thrombin generation profiles of four different rFVIII products in FVIII-deficient plasma using FIXa and FXIa activation.

Brophy DF, Martin EJ, Ninivaggi M, Mohammed BM, Barrett JC, Kuhn J, Nolte ME, Waters EK, Ezban M.

Haemophilia. 2018 Sep;24(5):815-822. doi: 10.1111/hae.13597. Epub 2018 Aug 16.

PMID:
30112856
17.

Hydromorphone-induced chorea as an atypical presentation of opioid neurotoxicity: A case report and review of the literature.

Martin EJ, Vaughan CL, Atayee R, Hirst JM, O'Donnell K, Edmonds KP.

Palliat Med. 2018 Oct;32(9):1529-1532. doi: 10.1177/0269216318786861. Epub 2018 Jul 13.

PMID:
30004301
18.

Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology.

Ziller MJ, Ortega JA, Quinlan KA, Santos DP, Gu H, Martin EJ, Galonska C, Pop R, Maidl S, Di Pardo A, Huang M, Meltzer HY, Gnirke A, Heckman CJ, Meissner A, Kiskinis E.

Cell Stem Cell. 2018 Apr 5;22(4):559-574.e9. doi: 10.1016/j.stem.2018.02.012. Epub 2018 Mar 15.

19.

Interventional vitamin C: A strategy for attenuation of coagulopathy and inflammation in a swine multiple injuries model.

Reynolds PS, Fisher BJ, McCarter J, Sweeney C, Martin EJ, Middleton P, Ellenberg M, Fowler E, Brophy DF, Fowler AA 3rd, Spiess BD, Natarajan R.

J Trauma Acute Care Surg. 2018 Jul;85(1S Suppl 2):S57-S67. doi: 10.1097/TA.0000000000001844.

PMID:
29538225
20.

Oncologic outcomes of extended neck dissections in human papillomavirus-related oropharyngeal squamous cell carcinoma.

Zenga J, Pipkorn P, Graboyes EM, Martin EJ, Rich JT, Moore EJ, Haughey BH, Jackson RS.

Head Neck. 2018 May;40(5):955-962. doi: 10.1002/hed.25060. Epub 2018 Jan 29.

PMID:
29377416
21.

Physiologically Based Pharmacokinetic Modeling in Lead Optimization. 1. Evaluation and Adaptation of GastroPlus To Predict Bioavailability of Medchem Series.

Daga PR, Bolger MB, Haworth IS, Clark RD, Martin EJ.

Mol Pharm. 2018 Mar 5;15(3):821-830. doi: 10.1021/acs.molpharmaceut.7b00972. Epub 2018 Feb 1.

PMID:
29337578
22.

Physiologically Based Pharmacokinetic Modeling in Lead Optimization. 2. Rational Bioavailability Design by Global Sensitivity Analysis To Identify Properties Affecting Bioavailability.

Daga PR, Bolger MB, Haworth IS, Clark RD, Martin EJ.

Mol Pharm. 2018 Mar 5;15(3):831-839. doi: 10.1021/acs.molpharmaceut.7b00973. Epub 2018 Feb 1.

PMID:
29337562
23.

Transoral robotic surgery for oropharyngeal carcinoma: Surgical margins and oncologic outcomes.

Moore EJ, Van Abel KM, Price DL, Lohse CM, Olsen KD, Jackson RS, Martin EJ.

Head Neck. 2018 Apr;40(4):747-755. doi: 10.1002/hed.25055. Epub 2018 Jan 12.

PMID:
29327784
24.

Modulation of the activated protein C pathway in severe haemophilia A patients: The effects of thrombomodulin and a factor V-stabilizing fab.

Brophy DF, Martin EJ, Mohammed BM, Barrett JC, Kuhn JG, Nolte ME, Wiinberg B, Holmberg HL, Lund J, Salbo R, Waters EK.

Haemophilia. 2017 Nov;23(6):941-947. doi: 10.1111/hae.13300. Epub 2017 Jul 27.

PMID:
28750471
25.

Reverse total shoulder glenoid baseplate stability with superior glenoid bone loss.

Martin EJ, Duquin TR, Ehrensberger MT.

J Shoulder Elbow Surg. 2017 Oct;26(10):1748-1755. doi: 10.1016/j.jse.2017.04.020. Epub 2017 Jul 6.

PMID:
28689820
26.

Profile-QSAR 2.0: Kinase Virtual Screening Accuracy Comparable to Four-Concentration IC50s for Realistically Novel Compounds.

Martin EJ, Polyakov VR, Tian L, Perez RC.

J Chem Inf Model. 2017 Aug 28;57(8):2077-2088. doi: 10.1021/acs.jcim.7b00166. Epub 2017 Jul 26.

PMID:
28651433
27.

Patient-Controlled Analgesia for Cancer-Related Pain: Clinical Predictors of Patient Outcomes.

Martin EJ, Roeland EJ, Sharp MB, Revta C, Murphy JD, Fero KE, Yeung HN.

J Natl Compr Canc Netw. 2017 May;15(5):595-600.

PMID:
28476739
28.

Management of Recurrent and Metastatic HPV-Positive Oropharyngeal Squamous Cell Carcinoma after Transoral Robotic Surgery.

Sims JR, Van Abel K, Martin EJ, Lohse CM, Price DL, Olsen KD, Moore EJ.

Otolaryngol Head Neck Surg. 2017 Jul;157(1):69-76. doi: 10.1177/0194599817696304. Epub 2017 Apr 4.

PMID:
28374634
29.

Impact of high dose vitamin C on platelet function.

Mohammed BM, Sanford KW, Fisher BJ, Martin EJ, Contaifer D Jr, Warncke UO, Wijesinghe DS, Chalfant CE, Brophy DF, Fowler Iii AA, Natarajan R.

World J Crit Care Med. 2017 Feb 4;6(1):37-47. doi: 10.5492/wjccm.v6.i1.37. eCollection 2017 Feb 4.

30.

Outcomes of surgically treated human papillomavirus-related oropharyngeal squamous cell carcinoma with N3 disease.

Zenga J, Haughey BH, Jackson RS, Adkins DR, Aranake-Chrisinger J, Bhatt N, Gay HA, Kallogjeri D, Martin EJ, Moore EJ, Paniello RC, Rich JT, Thorstad WL, Nussenbaum B.

Laryngoscope. 2017 Sep;127(9):2033-2037. doi: 10.1002/lary.26455. Epub 2016 Dec 23.

PMID:
28008626
31.

Unsupervised analysis of combined lipid and coagulation data reveals coagulopathy subtypes among dialysis patients.

Contaifer D Jr, Carl DE, Warncke UO, Martin EJ, Mohammed BM, Van Tassell B, Brophy DF, Chalfant CE, Wijesinghe DS.

J Lipid Res. 2017 Mar;58(3):586-599. doi: 10.1194/jlr.P068833. Epub 2016 Dec 19.

32.

Hemifacial Spasm Secondary to Parotid Pleomorphic Adenoma With Stylomastoid Foramen Extension.

Martin EJ, Carlson ML, Moore EJ, Jackson RS.

Otol Neurotol. 2017 Jan;38(1):129-132. Review.

PMID:
27755360
33.

Oncologic outcomes of selective neck dissection in HPV-related oropharyngeal squamous cell carcinoma.

Zenga J, Jackson RS, Graboyes EM, Sinha P, Lindberg M, Martin EJ, Ma D, Thorstad WL, Rich JT, Moore EJ, Haughey BH.

Laryngoscope. 2017 Mar;127(3):623-630. doi: 10.1002/lary.26272. Epub 2016 Sep 16.

PMID:
27634021
34.

Blockade of orexin receptors attenuates the cardiovascular response to air-jet stress in spontaneously hypertensive rats.

Martin EJ, Hernandez ME, Hayward LF.

Auton Neurosci. 2016 Dec;201:8-16. doi: 10.1016/j.autneu.2016.08.012. Epub 2016 Aug 22.

PMID:
27591948
35.

Efficacy and safety of point-of-care ultrasound-guided intra-articular corticosteroid joint injections in patients with haemophilic arthropathy.

Martin EJ, Cooke EJ, Ceponis A, Barnes RF, Moran CM, Holle S, Hughes TH, Moore RE, von Drygalski A.

Haemophilia. 2017 Jan;23(1):135-143. doi: 10.1111/hae.13057. Epub 2016 Aug 3.

PMID:
27486060
36.

Anodic Electrodeposition of a Cationic Polyelectrolyte in the Presence of Multivalent Anions.

Martin EJ, Sadman K, Shull KR.

Langmuir. 2016 Aug 9;32(31):7747-56. doi: 10.1021/acs.langmuir.6b01536. Epub 2016 Jul 28.

PMID:
27419476
37.

HEALTHCARE POLICY LEGISLATION AND ADMINISTRATION: PATIENT PROTECTION AND AFFORDABLE CARE ACT OF 2010.

Martin EJ.

J Health Hum Serv Adm. 2015 Spring;37(4):407-11. No abstract available.

PMID:
27149760
38.

Post-translational oxidative modification of fibrinogen is associated with coagulopathy after traumatic injury.

White NJ, Wang Y, Fu X, Cardenas JC, Martin EJ, Brophy DF, Wade CE, Wang X, St John AE, Lim EB, Stern SA, Ward KR, López JA, Chung D.

Free Radic Biol Med. 2016 Jul;96:181-9. doi: 10.1016/j.freeradbiomed.2016.04.023. Epub 2016 Apr 20.

39.

Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin.

Mehta AY, Mohammed BM, Martin EJ, Brophy DF, Gailani D, Desai UR.

J Thromb Haemost. 2016 Apr;14(4):828-38. doi: 10.1111/jth.13254. Epub 2016 Feb 16.

40.

Coated platelet assay: a feasible approach to a complicated science.

Mohammed BM, Contaifer D Jr, Lastrapes KK, Martin EJ, Mazepa MA, Hoffman M, Monroe DM, Brophy DF.

Haemophilia. 2016 Jan;22(1):e67-70. doi: 10.1111/hae.12845. Epub 2015 Nov 26. No abstract available.

PMID:
26612351
41.

Coated platelets and severe haemophilia A bleeding phenotype: Is there a connection?

Lastrapes KK, Mohammed BM, Mazepa MA, Martin EJ, Barrett JC, Massey GV, Kuhn JG, Nolte ME, Hoffman M, Monroe DM, Brophy DF.

Haemophilia. 2016 Jan;22(1):148-51. doi: 10.1111/hae.12844. Epub 2015 Nov 11.

PMID:
26561343
42.

MEDICAL BRIGADES, GLOBAL HEALTH AND THE UNITED NATIONS: MILLENNIUM DEVELOPMENT GOALS AND DEVELOPING NATIONS.

Portman MT, Martin EJ.

J Health Hum Serv Adm. 2015 Summer;38(1):90-107.

PMID:
26369236
43.

AFFORDABLE HOUSING, HOMELESSNESS, AND MENTAL HEALTH: WHAT HEATH CARE POLICY NEEDS TO ADDRESS.

Martin EJ.

J Health Hum Serv Adm. 2015 Summer;38(1):67-89. No abstract available.

PMID:
26369235
44.

Prefabricated auricular cartilage radial forearm free flap reconstruction for cricoid chondrosarcoma.

Jackson RS, Martin EJ, Moore EJ.

Laryngoscope. 2015 Nov;125(11):2514-7. doi: 10.1002/lary.25510. Epub 2015 Jul 30.

PMID:
26228709
45.

Chronic heart failure alters orexin and melanin concentrating hormone but not corticotrophin releasing hormone-related gene expression in the brain of male Lewis rats.

Hayward LF, Hampton EE, Ferreira LF, Christou DD, Yoo JK, Hernandez ME, Martin EJ.

Neuropeptides. 2015 Aug;52:67-72. doi: 10.1016/j.npep.2015.06.001. Epub 2015 Jun 11.

PMID:
26111703
46.

Early hemostatic responses to trauma identified with hierarchical clustering analysis.

White NJ, Contaifer D Jr, Martin EJ, Newton JC, Mohammed BM, Bostic JL, Brophy GM, Spiess BD, Pusateri AE, Ward KR, Brophy DF.

J Thromb Haemost. 2015 Jun;13(6):978-88. doi: 10.1111/jth.12919. Epub 2015 May 9.

47.

Viscoelastic properties of electrochemically deposited protein/metal complexes.

Martin EJ, Mathew MT, Shull KR.

Langmuir. 2015 Apr 7;31(13):4008-17. doi: 10.1021/acs.langmuir.5b00169. Epub 2015 Mar 25.

PMID:
25780816
48.

Laboratory assessment of warfarin reversal with global coagulation tests versus international normalized ratio in patients with intracranial bleeding.

Voils SA, Martin EJ, Mohammed BM, Bayrlee A, Brophy DF.

Blood Coagul Fibrinolysis. 2015 Jun;26(4):443-7. doi: 10.1097/MBC.0000000000000270.

PMID:
25699612
49.

Clot Formation Is Associated With Fibrinogen and Platelet Forces in a Cohort of Severely Injured Emergency Department Trauma Patients.

White NJ, Newton JC, Martin EJ, Mohammed BM, Contaifer D Jr, Bostic JL, Brophy GM, Spiess BD, Pusateri AE, Ward KR, Brophy DF.

Shock. 2015 Aug;44 Suppl 1:39-44. doi: 10.1097/SHK.0000000000000342.

50.

Intact stable isotope labeled plasma proteins from the SILAC-labeled HepG2 secretome.

Mangrum JB, Martin EJ, Brophy DF, Hawkridge AM.

Proteomics. 2015 Sep;15(18):3104-15. doi: 10.1002/pmic.201400369. Epub 2015 Feb 14.

PMID:
25504855

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