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Items: 1 to 50 of 129

1.

Dual actions of group B Streptococcus capsular sialic acid provide resistance to platelet-mediated antimicrobial killing.

Uchiyama S, Sun J, Fukahori K, Ando N, Wu M, Schwarz F, Siddiqui SS, Varki A, Marth JD, Nizet V.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7465-7470. doi: 10.1073/pnas.1815572116. Epub 2019 Mar 25.

PMID:
30910970
2.

Plasma Proteome Signature of Sepsis: a Functionally Connected Protein Network.

Pimienta G, Heithoff DM, Rosa-Campos A, Tran M, Esko JD, Mahan MJ, Marth JD, Smith JW.

Proteomics. 2019 Mar;19(5):e1800389. doi: 10.1002/pmic.201800389. Epub 2019 Feb 20.

PMID:
30706660
3.

Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis.

Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD.

Cell Host Microbe. 2018 Oct 10;24(4):500-513.e5. doi: 10.1016/j.chom.2018.09.011.

PMID:
30308156
4.

Smartphone-based pathogen diagnosis in urinary sepsis patients.

Barnes L, Heithoff DM, Mahan SP, Fox GN, Zambrano A, Choe J, Fitzgibbons LN, Marth JD, Fried JC, Soh HT, Mahan MJ.

EBioMedicine. 2018 Oct;36:73-82. doi: 10.1016/j.ebiom.2018.09.001. Epub 2018 Sep 20.

5.

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.

Matsubara N, Imamura A, Yonemizu T, Akatsu C, Yang H, Ueki A, Watanabe N, Abdu-Allah H, Numoto N, Takematsu H, Kitazume S, Tedder TF, Marth JD, Ito N, Ando H, Ishida H, Kiso M, Tsubata T.

Front Immunol. 2018 Apr 19;9:820. doi: 10.3389/fimmu.2018.00820. eCollection 2018.

6.

Recurrent infection progressively disables host protection against intestinal inflammation.

Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD.

Science. 2017 Dec 22;358(6370). pii: eaao5610. doi: 10.1126/science.aao5610.

7.

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.

Yamasaki T, Deki-Arima N, Kaneko A, Miyamura N, Iwatsuki M, Matsuoka M, Fujimori-Tonou N, Okamoto-Uchida Y, Hirayama J, Marth JD, Yamanashi Y, Kawasaki H, Yamanaka K, Penninger JM, Shibata S, Nishina H.

Sci Rep. 2017 Aug 4;7(1):7348. doi: 10.1038/s41598-017-07845-x.

8.

Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells.

Li Y, Fu J, Ling Y, Yago T, McDaniel JM, Song J, Bai X, Kondo Y, Qin Y, Hoover C, McGee S, Shao B, Liu Z, Sonon R, Azadi P, Marth JD, McEver RP, Ruan C, Xia L.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8360-8365. doi: 10.1073/pnas.1707662114. Epub 2017 Jul 17.

9.

Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing.

Ersoy SC, Heithoff DM, Barnes L 5th, Tripp GK, House JK, Marth JD, Smith JW, Mahan MJ.

EBioMedicine. 2017 Jun;20:173-181. doi: 10.1016/j.ebiom.2017.05.026. Epub 2017 May 29.

10.

Protein glycosylation energizes T cells.

Yang WH, Marth JD.

Nat Immunol. 2016 May 19;17(6):613-4. doi: 10.1038/ni.3468. No abstract available.

PMID:
27196512
11.

Symbol Nomenclature for Graphical Representations of Glycans.

Varki A, Cummings RD, Aebi M, Packer NH, Seeberger PH, Esko JD, Stanley P, Hart G, Darvill A, Kinoshita T, Prestegard JJ, Schnaar RL, Freeze HH, Marth JD, Bertozzi CR, Etzler ME, Frank M, Vliegenthart JF, Lütteke T, Perez S, Bolton E, Rudd P, Paulson J, Kanehisa M, Toukach P, Aoki-Kinoshita KF, Dell A, Narimatsu H, York W, Taniguchi N, Kornfeld S.

Glycobiology. 2015 Dec;25(12):1323-4. doi: 10.1093/glycob/cwv091. No abstract available.

12.

Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure.

Kubicek-Sutherland JZ, Heithoff DM, Ersoy SC, Shimp WR, House JK, Marth JD, Smith JW, Mahan MJ.

EBioMedicine. 2015 Aug 11;2(9):1169-78. doi: 10.1016/j.ebiom.2015.08.012. eCollection 2015 Sep.

13.

An intrinsic mechanism of secreted protein aging and turnover.

Yang WH, Aziz PV, Heithoff DM, Mahan MJ, Smith JW, Marth JD.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13657-62. doi: 10.1073/pnas.1515464112. Epub 2015 Oct 21.

14.

Deficiency of the sialyltransferase St3Gal4 reduces Ccl5-mediated myeloid cell recruitment and arrest: short communication.

Döring Y, Noels H, Mandl M, Kramp B, Neideck C, Lievens D, Drechsler M, Megens RT, Tilstam PV, Langer M, Hartwig H, Theelen W, Marth JD, Sperandio M, Soehnlein O, Weber C.

Circ Res. 2014 Mar 14;114(6):976-81. doi: 10.1161/CIRCRESAHA.114.302426. Epub 2014 Jan 14.

15.

Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor.

Grewal PK, Aziz PV, Uchiyama S, Rubio GR, Lardone RD, Le D, Varki NM, Nizet V, Marth JD.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20218-23. doi: 10.1073/pnas.1313905110. Epub 2013 Nov 27.

16.

Quantitative selection and parallel characterization of aptamers.

Cho M, Soo Oh S, Nie J, Stewart R, Eisenstein M, Chambers J, Marth JD, Walker F, Thomson JA, Soh HT.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18460-5. doi: 10.1073/pnas.1315866110. Epub 2013 Oct 28.

17.

Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes.

Luni C, Marth JD, Doyle FJ 3rd.

PLoS One. 2012;7(12):e53130. doi: 10.1371/journal.pone.0053130. Epub 2012 Dec 27.

18.

A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.

Orr SL, Le D, Long JM, Sobieszczuk P, Ma B, Tian H, Fang X, Paulson JC, Marth JD, Varki N.

Glycobiology. 2013 Mar;23(3):363-80. doi: 10.1093/glycob/cws150. Epub 2012 Oct 31.

19.

Biosynthesis of the major brain gangliosides GD1a and GT1b.

Sturgill ER, Aoki K, Lopez PH, Colacurcio D, Vajn K, Lorenzini I, Majić S, Yang WH, Heffer M, Tiemeyer M, Marth JD, Schnaar RL.

Glycobiology. 2012 Oct;22(10):1289-301. doi: 10.1093/glycob/cws103. Epub 2012 Jun 26.

20.

Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands.

Yang WH, Nussbaum C, Grewal PK, Marth JD, Sperandio M.

Blood. 2012 Aug 2;120(5):1015-26. doi: 10.1182/blood-2012-04-424366. Epub 2012 Jun 13.

21.

Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport.

Ohtsubo K, Chen MZ, Olefsky JM, Marth JD.

Nat Med. 2011 Aug 14;17(9):1067-75. doi: 10.1038/nm.2414.

22.

High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases.

Ismail MN, Stone EL, Panico M, Lee SH, Luu Y, Ramirez K, Ho SB, Fukuda M, Marth JD, Haslam SM, Dell A.

Glycobiology. 2011 Jan;21(1):82-98. doi: 10.1093/glycob/cwq134. Epub 2010 Sep 20.

23.

Core2 O-glycan structure is essential for the cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV during intestinal cell differentiation.

Lee SH, Yu SY, Nakayama J, Khoo KH, Stone EL, Fukuda MN, Marth JD, Fukuda M.

J Biol Chem. 2010 Nov 26;285(48):37683-92. doi: 10.1074/jbc.M110.162735. Epub 2010 Sep 14.

24.

Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.

Kitazume S, Imamaki R, Ogawa K, Komi Y, Futakawa S, Kojima S, Hashimoto Y, Marth JD, Paulson JC, Taniguchi N.

J Biol Chem. 2010 Feb 26;285(9):6515-21. doi: 10.1074/jbc.M109.073106. Epub 2010 Jan 4.

25.

Physiological and glycomic characterization of N-acetylglucosaminyltransferase-IVa and -IVb double deficient mice.

Takamatsu S, Antonopoulos A, Ohtsubo K, Ditto D, Chiba Y, Le DT, Morris HR, Haslam SM, Dell A, Marth JD, Taniguchi N.

Glycobiology. 2010 Jan;20(4):485-97. doi: 10.1093/glycob/cwp200. Epub 2009 Dec 16.

26.

Symbol nomenclature for glycan representation.

Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Marth JD, Bertozzi CR, Hart GW, Etzler ME.

Proteomics. 2009 Dec;9(24):5398-9. doi: 10.1002/pmic.200900708.

27.

Dual roles for hepatic lectin receptors in the clearance of chilled platelets.

Rumjantseva V, Grewal PK, Wandall HH, Josefsson EC, Sørensen AL, Larson G, Marth JD, Hartwig JH, Hoffmeister KM.

Nat Med. 2009 Nov;15(11):1273-80. doi: 10.1038/nm.2030. Epub 2009 Sep 27.

28.

Regulated and aberrant glycosylation modulate cardiac electrical signaling.

Montpetit ML, Stocker PJ, Schwetz TA, Harper JM, Norring SA, Schaffer L, North SJ, Jang-Lee J, Gilmartin T, Head SR, Haslam SM, Dell A, Marth JD, Bennett ES.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16517-22. doi: 10.1073/pnas.0905414106. Epub 2009 Aug 7.

29.

Core2 1-6-N-glucosaminyltransferase-I deficiency protects injured arteries from neointima formation in ApoE-deficient mice.

Wang H, Zhang W, Tang R, Hebbel RP, Kowalska MA, Zhang C, Marth JD, Fukuda M, Zhu C, Huo Y.

Arterioscler Thromb Vasc Biol. 2009 Jul;29(7):1053-9. doi: 10.1161/ATVBAHA.109.187716. Epub 2009 Apr 16.

30.

Glycosyltransferase function in core 2-type protein O glycosylation.

Stone EL, Ismail MN, Lee SH, Luu Y, Ramirez K, Haslam SM, Ho SB, Dell A, Fukuda M, Marth JD.

Mol Cell Biol. 2009 Jul;29(13):3770-82. doi: 10.1128/MCB.00204-09. Epub 2009 Apr 6.

31.

Core2 1-6-N-glucosaminyltransferase-I is crucial for the formation of atherosclerotic lesions in apolipoprotein E-deficient mice.

Wang H, Tang R, Zhang W, Amirikian K, Geng Z, Geng J, Hebbel RP, Xia L, Marth JD, Fukuda M, Katoh S, Huo Y.

Arterioscler Thromb Vasc Biol. 2009 Feb;29(2):180-7. doi: 10.1161/ATVBAHA.108.170969. Epub 2008 Dec 4.

32.

Mammalian glycosylation in immunity.

Marth JD, Grewal PK.

Nat Rev Immunol. 2008 Nov;8(11):874-87. doi: 10.1038/nri2417. Review.

33.

A unified vision of the building blocks of life.

Marth JD.

Nat Cell Biol. 2008 Sep;10(9):1015-6. doi: 10.1038/ncb0908-1015. No abstract available.

34.

Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.

Frommhold D, Ludwig A, Bixel MG, Zarbock A, Babushkina I, Weissinger M, Cauwenberghs S, Ellies LG, Marth JD, Beck-Sickinger AG, Sixt M, Lange-Sperandio B, Zernecke A, Brandt E, Weber C, Vestweber D, Ley K, Sperandio M.

J Exp Med. 2008 Jun 9;205(6):1435-46. doi: 10.1084/jem.20070846. Epub 2008 Jun 2.

35.

The Ashwell receptor mitigates the lethal coagulopathy of sepsis.

Grewal PK, Uchiyama S, Ditto D, Varki N, Le DT, Nizet V, Marth JD.

Nat Med. 2008 Jun;14(6):648-55. doi: 10.1038/nm1760. Epub 2008 May 18.

36.

Dendritic cell-dependent inhibition of B cell proliferation requires CD22.

Santos L, Draves KE, Boton M, Grewal PK, Marth JD, Clark EA.

J Immunol. 2008 Apr 1;180(7):4561-9.

37.

Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity.

Tenno M, Ohtsubo K, Hagen FK, Ditto D, Zarbock A, Schaerli P, von Andrian UH, Ley K, Le D, Tabak LA, Marth JD.

Mol Cell Biol. 2007 Dec;27(24):8783-96. Epub 2007 Oct 8.

38.

Beta-galactoside alpha2,6-sialyltransferase I cleavage by BACE1 enhances the sialylation of soluble glycoproteins. A novel regulatory mechanism for alpha2,6-sialylation.

Sugimoto I, Futakawa S, Oka R, Ogawa K, Marth JD, Miyoshi E, Taniguchi N, Hashimoto Y, Kitazume S.

J Biol Chem. 2007 Nov 30;282(48):34896-903. Epub 2007 Sep 26.

39.

Polysialic acid-directed migration and differentiation of neural precursors are essential for mouse brain development.

Angata K, Huckaby V, Ranscht B, Terskikh A, Marth JD, Fukuda M.

Mol Cell Biol. 2007 Oct;27(19):6659-68. Epub 2007 Aug 6.

40.

Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis.

Green RS, Stone EL, Tenno M, Lehtonen E, Farquhar MG, Marth JD.

Immunity. 2007 Aug;27(2):308-20. Epub 2007 Aug 2.

41.

T-cell activation results in microheterogeneous changes in glycosylation of CD45.

Hernandez JD, Klein J, Van Dyken SJ, Marth JD, Baum LG.

Int Immunol. 2007 Jul;19(7):847-56. Epub 2007 Jul 2.

PMID:
17606981
42.

Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment.

Mitoma J, Bao X, Petryanik B, Schaerli P, Gauguet JM, Yu SY, Kawashima H, Saito H, Ohtsubo K, Marth JD, Khoo KH, von Andrian UH, Lowe JB, Fukuda M.

Nat Immunol. 2007 Apr;8(4):409-18. Epub 2007 Mar 4.

PMID:
17334369
43.

Conditional mutagenesis of the genome using site-specific DNA recombination.

Ohtsubo K, Marth JD.

CSH Protoc. 2007 Jul 1;2007:pdb.top12. doi: 10.1101/pdb.top12.

PMID:
21357131
44.

Cre Recombinase Gene Transfer In Vitro and Detection of loxP-Dependent Recombination.

Ohtsubo K, Marth JD.

CSH Protoc. 2007 Jul 1;2007:pdb.prot4762. doi: 10.1101/pdb.prot4762.

PMID:
21357118
45.

Genome Modification by Inclusion of loxP Transgene Sequences.

Ohtsubo K, Marth JD.

CSH Protoc. 2007 Jul 1;2007:pdb.prot4761. doi: 10.1101/pdb.prot4761.

PMID:
21357117
46.

Cellular and molecular analysis of neural development of glycosyltransferase gene knockout mice.

Angata K, Lee W, Mitoma J, Marth JD, Fukuda M.

Methods Enzymol. 2006;417:25-37. Review.

PMID:
17132495
47.

Alpha 2,3-sialyltransferase-IV is essential for L-selectin ligand function in inflammation.

Sperandio M, Frommhold D, Babushkina I, Ellies LG, Olson TS, Smith ML, Fritzsching B, Pauly E, Smith DF, Nobiling R, Linderkamp O, Marth JD, Ley K.

Eur J Immunol. 2006 Dec;36(12):3207-15.

48.

Structural and mechanistic features of protein O glycosylation linked to CD8+ T-cell apoptosis.

Van Dyken SJ, Green RS, Marth JD.

Mol Cell Biol. 2007 Feb;27(3):1096-111. Epub 2006 Nov 13.

49.

Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics.

Zheng B, Tang T, Tang N, Kudlicka K, Ohtsubo K, Ma P, Marth JD, Farquhar MG, Lehtonen E.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16776-81. Epub 2006 Oct 31.

50.

Glycosylation in cellular mechanisms of health and disease.

Ohtsubo K, Marth JD.

Cell. 2006 Sep 8;126(5):855-67. Review.

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