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Items: 1 to 50 of 120

1.

Homoarginine Supplementation Prevents Left Ventricular Dilatation and Preserves Systolic Function in a Model of Coronary Artery Disease.

Rodionov RN, Begmatov H, Jarzebska N, Patel K, Mills MT, Ghani Z, Khakshour D, Tamboli P, Patel MN, Abdalla M, Assaf M, Bornstein SR, Millan JL, Bode-Böger SM, Martens-Lobenhoffer J, Weiss N, Savinova OV.

J Am Heart Assoc. 2019 Jul 16;8(14):e012486. doi: 10.1161/JAHA.119.012486. Epub 2019 Jul 15.

PMID:
31304837
Free Article
2.

Stability of meropenem in plasma versus dried blood spots (DBS).

Martens-Lobenhoffer J, Monastyrski D, Tröger U, Bode-Böger SM.

J Pharm Biomed Anal. 2019 Jun 5;170:279-284. doi: 10.1016/j.jpba.2019.03.055. Epub 2019 Mar 25.

PMID:
30947129
3.

Plasma Dimethylarginine Levels and Carotid Intima-Media Thickness are related to Atrial Fibrillation in Patients with Embolic Stroke.

Grosse GM, Biber S, Sieweke JT, Martens-Lobenhoffer J, Gabriel MM, Putzer AS, Hasse I, van Gemmeren T, Schuppner R, Worthmann H, Lichtinghagen R, Bode-Böger SM, Bavendiek U, Weissenborn K.

Int J Mol Sci. 2019 Feb 9;20(3). pii: E730. doi: 10.3390/ijms20030730.

4.

Single- and multiple-dose pharmacokinetics and total removal of colistin in critically ill patients with acute kidney injury undergoing prolonged intermittent renal replacement therapy.

Schmidt JJ, Strunk AK, David S, Bode-Böger SM, Martens-Lobenhoffer J, Knitsch W, Scherneck S, Welte T, Kielstein JT.

J Antimicrob Chemother. 2019 Apr 1;74(4):997-1002. doi: 10.1093/jac/dky511.

PMID:
30624668
5.

L-Homoarginine and its AGXT2-metabolite GOCA in chronic kidney disease as markers for clinical status and prognosis.

Martens-Lobenhoffer J, Emrich IE, Zawada AM, Fliser D, Wagenpfeil S, Heine GH, Bode-Böger SM.

Amino Acids. 2018 Oct;50(10):1347-1356. doi: 10.1007/s00726-018-2610-y. Epub 2018 Jul 7.

PMID:
29982953
6.

ADAMTS-13 Activity Predicts Outcome in Acute Ischaemic Stroke Patients Undergoing Endovascular Treatment.

Schuppner R, Dirks M, Grosse GM, Böckmann M, Goetz F, Pasedag T, Bode-Böger SM, Martens-Lobenhoffer J, Budde U, Lanfermann H, Lichtinghagen R, Weissenborn K, Worthmann H.

Thromb Haemost. 2018 Apr;118(4):758-767. doi: 10.1055/s-0038-1637732. Epub 2018 Apr 4.

PMID:
29618156
7.

Dimethylarginines in patients with intracerebral hemorrhage: association with outcome, hematoma enlargement, and edema.

Worthmann H, Li N, Martens-Lobenhoffer J, Dirks M, Schuppner R, Lichtinghagen R, Kielstein JT, Raab P, Lanfermann H, Bode-Böger SM, Weissenborn K.

J Neuroinflammation. 2017 Dec 13;14(1):247. doi: 10.1186/s12974-017-1016-1.

8.

Symmetric dimethylarginine (SDMA) outperforms asymmetric dimethylarginine (ADMA) and other methylarginines as predictor of renal and cardiovascular outcome in non-dialysis chronic kidney disease.

Emrich IE, Zawada AM, Martens-Lobenhoffer J, Fliser D, Wagenpfeil S, Heine GH, Bode-Böger SM.

Clin Res Cardiol. 2018 Mar;107(3):201-213. doi: 10.1007/s00392-017-1172-4. Epub 2017 Nov 3.

PMID:
29101459
9.

ADMA reduction does not protect mice with streptozotocin-induced diabetes mellitus from development of diabetic nephropathy.

Rodionov RN, Heinrich A, Brilloff S, Jarzebska N, Martens-Lobenhoffer J, Bode-Böger SM, Todorov VT, Hugo CPM, Weiss N, Hohenstein B.

Atheroscler Suppl. 2017 Nov;30:319-325. doi: 10.1016/j.atherosclerosissup.2017.05.031. Epub 2017 Jun 1.

PMID:
29096857
10.

Quantification of meropenem in human plasma by HILIC - tandem mass spectrometry.

Martens-Lobenhoffer J, Bode-Böger SM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 1;1046:13-17. doi: 10.1016/j.jchromb.2017.01.016. Epub 2017 Jan 19.

PMID:
28126443
11.

Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.

Burdin DV, Kolobov AA, Brocker C, Soshnev AA, Samusik N, Demyanov AV, Brilloff S, Jarzebska N, Martens-Lobenhoffer J, Mieth M, Maas R, Bornstein SR, Bode-Böger SM, Gonzalez F, Weiss N, Rodionov RN.

Sci Rep. 2016 Oct 18;6:35503. doi: 10.1038/srep35503.

12.

A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2.

Rodionov RN, Oppici E, Martens-Lobenhoffer J, Jarzebska N, Brilloff S, Burdin D, Demyanov A, Kolouschek A, Leiper J, Maas R, Cellini B, Weiss N, Bode-Böger SM.

Sci Rep. 2016 Oct 18;6:35277. doi: 10.1038/srep35277.

13.

Pharmacokinetics and total removal of fosfomycin in two patients undergoing intermittent haemodialysis and extended dialysis: prescription needs to avoid under-dosing.

Schmidt JJ, Bode-Böger SM, Wilhelmi M, Omar M, Martens-Lobenhoffer J, Welte T, Kielstein JT.

J Antimicrob Chemother. 2016 Sep;71(9):2673-4. doi: 10.1093/jac/dkw187. Epub 2016 Jun 5. No abstract available.

PMID:
27272722
14.

Acute interstitial nephritis due to flecainide therapy in the 38(th) week of pregnancy.

Schmidt JJ, Ramazan L, Bockemeyer C, Günter HH, Martens-Lobenhoffer J, Ganzenmüller T, Bode-Böger SM, Kielstein JT.

BMC Nephrol. 2016 Mar 15;17:28. doi: 10.1186/s12882-016-0240-8.

15.

Acetylation of asymmetric and symmetric dimethylarginine: an undercharacterized pathway of metabolism of endogenous methylarginines.

Rodionov RN, Martens-Lobenhoffer J, Brilloff S, Burdin DV, Jarzebska N, Demyanov AV, Hohenstein B, Weiss N, Bode-Böger SM.

Nephrol Dial Transplant. 2016 Jan;31(1):57-63. doi: 10.1093/ndt/gfv390. Epub 2015 Nov 25.

PMID:
26610597
16.

First detection and quantification of N(δ)-monomethylarginine, a structural isomer of N(G)-monomethylarginine, in humans using MS(3).

Martens-Lobenhoffer J, Bode-Böger SM, Clement B.

Anal Biochem. 2016 Jan 15;493:14-20. doi: 10.1016/j.ab.2015.10.001. Epub 2015 Oct 20.

PMID:
26464121
17.

Role of the endogenous nitric oxide inhibitor asymmetric dimethylarginine (ADMA) and brain-derived neurotrophic factor (BDNF) in depression and behavioural changes: clinical and preclinical data in chronic kidney disease.

Kielstein H, Suntharalingam M, Perthel R, Song R, Schneider SM, Martens-Lobenhoffer J, Jäger K, Bode-Böger SM, Kielstein JT.

Nephrol Dial Transplant. 2015 Oct;30(10):1699-705. doi: 10.1093/ndt/gfv253. Epub 2015 Jul 13.

PMID:
26175142
18.

A validated method for the quantification of fosfomycin in human plasma by liquid chromatography-tandem mass spectrometry.

Martens-Lobenhoffer J, Bode-Böger SM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 May 15;990:164-8. doi: 10.1016/j.jchromb.2015.03.029. Epub 2015 Apr 3.

PMID:
25875589
19.

Amino acid N-acetylation: metabolic elimination of symmetric dimethylarginine as symmetric N(α)-acetyldimethylarginine, determined in human plasma and urine by LC-MS/MS.

Martens-Lobenhoffer J, Bode-Böger SM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jan 15;975:59-64. doi: 10.1016/j.jchromb.2014.11.009. Epub 2014 Nov 20.

PMID:
25438244
20.

Successful treatment of extensively drug-resistant Pseudomonas aeruginosa osteomyelitis using a colistin- and tobramycin-impregnated PMMA spacer.

Krajewski J, Bode-Böger SM, Tröger U, Martens-Lobenhoffer J, Mulrooney T, Mittelstädt H, Russlies M, Kirchner R, Knobloch JK.

Int J Antimicrob Agents. 2014 Oct;44(4):363-6. doi: 10.1016/j.ijantimicag.2014.05.023. Epub 2014 Aug 13.

PMID:
25182711
21.

Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy.

Rodionov RN, Martens-Lobenhoffer J, Brilloff S, Hohenstein B, Jarzebska N, Jabs N, Kittel A, Maas R, Weiss N, Bode-Böger SM.

Nephrol Dial Transplant. 2014 Nov;29(11):2035-42. doi: 10.1093/ndt/gfu236. Epub 2014 Jul 6.

PMID:
25002409
22.

Single- and multiple-dose pharmacokinetics and total removal of colistin in a patient with acute kidney injury undergoing extended daily dialysis.

Strunk AK, Schmidt JJ, Baroke E, Bode-Böger SM, Martens-Lobenhoffer J, Welte T, Kielstein JT.

J Antimicrob Chemother. 2014 Jul;69(7):2008-10. doi: 10.1093/jac/dku075. Epub 2014 Mar 20. No abstract available.

PMID:
24651826
23.

Determination of asymmetric Nα-acetyldimethylarginine in humans: a phase II metabolite of asymmetric dimethylarginine.

Martens-Lobenhoffer J, Rodionov RN, Bode-Böger SM.

Anal Biochem. 2014 May 1;452:25-30. doi: 10.1016/j.ab.2014.02.016. Epub 2014 Feb 20.

PMID:
24560726
24.

Mass spectrometric quantification of L-arginine and its pathway related substances in biofluids: the road to maturity.

Martens-Lobenhoffer J, Bode-Böger SM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Aug 1;964:89-102. doi: 10.1016/j.jchromb.2013.10.030. Epub 2013 Oct 26. Review.

PMID:
24210895
25.

Opposite associations of plasma homoarginine and ornithine with arginine in healthy children and adolescents.

Jaźwińska-Kozuba A, Martens-Lobenhoffer J, Kruszelnicka O, Rycaj J, Chyrchel B, Surdacki A, Bode-Böger SM.

Int J Mol Sci. 2013 Nov 4;14(11):21819-32. doi: 10.3390/ijms141121819.

26.

Intravenous colistin in a patient with serious burns and borderline syndrome: the benefits of therapeutic drug monitoring.

Bode-Böger SM, Schopp B, Tröger U, Martens-Lobenhoffer J, Kalousis K, Mailänder P.

Int J Antimicrob Agents. 2013 Oct;42(4):357-60. doi: 10.1016/j.ijantimicag.2013.06.009. Epub 2013 Sep 5.

PMID:
24011987
27.

Asymmetric dimethylarginine in response to recombinant tissue-type plasminogen activator and erythropoietin in acute stroke.

Worthmann H, Martens-Lobenhoffer J, Joumaah M, Li N, Lichtinghagen R, Hecker H, Kielstein JT, Ehrenreich H, Bode-Böger SM, Weissenborn K.

Stroke. 2013 Aug;44(8):2128-33. doi: 10.1161/STROKEAHA.113.001145. Epub 2013 Jun 20.

PMID:
23788583
28.

L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies.

Tamás P, Bódis J, Sulyok E, Kovács GL, Hantosi E, Molnár G, Martens-Lobenhoffer J, Bode-Böger SM.

Scand J Clin Lab Invest. 2013 Aug;73(5):436-43. doi: 10.3109/00365513.2013.803230. Epub 2013 Jun 18.

PMID:
23777299
29.

Symmetrical dimethylarginine is superior to NT-proBNP for detecting systemic ventricular dysfunction in adults after atrial repair for transposition of the great arteries.

Tutarel O, Röntgen P, Bode-Böger SM, Martens-Lobenhoffer J, Westhoff-Bleck M, Diller GP, Bauersachs J, Kielstein JT.

Int J Cardiol. 2013 Oct 9;168(4):4415-6. doi: 10.1016/j.ijcard.2013.05.030. Epub 2013 May 24. No abstract available.

PMID:
23711443
30.

Effects of chronic SDMA infusion on glomerular filtration rate, blood pressure, myocardial function and renal histology in C57BL6/J mice.

Veldink H, Faulhaber-Walter R, Park JK, Martens-Lobenhoffer J, Bode-Böger S, Schuett H, Haghikia A, Hilfiker-Kleiner D, Kielstein JT.

Nephrol Dial Transplant. 2013 Jun;28(6):1434-9. doi: 10.1093/ndt/gfs554. Epub 2013 Jan 4.

PMID:
23291365
31.

Probing AGXT2 enzyme activity in mouse tissue by applying stable isotope-labeled asymmetric dimethyl arginine as substrate.

Martens-Lobenhoffer J, Rodionov RN, Bode-Böger SM.

J Mass Spectrom. 2012 Dec;47(12):1594-600. doi: 10.1002/jms.3125.

PMID:
23280748
32.

Effect of chronic elevated asymmetric dimethylarginine (ADMA) levels on granulopoiesis.

Beutel G, Perthel R, Suntharalingam M, Bode-Böger SM, Martens-Lobenhoffer J, Kielstein JT, Kielstein H.

Ann Hematol. 2013 Apr;92(4):505-8. doi: 10.1007/s00277-012-1636-6. Epub 2012 Dec 6.

PMID:
23224243
33.

Indoleamine-2,3-dioxygenase activity in experimental human endotoxemia.

Padberg JS, Van Meurs M, Kielstein JT, Martens-Lobenhoffer J, Bode-Böger SM, Zijlstra JG, Kovesdy CP, Kümpers P.

Exp Transl Stroke Med. 2012 Dec 5;4(1):24. doi: 10.1186/2040-7378-4-24.

34.

Associations between endogenous dimethylarginines and renal function in healthy children and adolescents.

Jaźwińska-Kozuba A, Martens-Lobenhoffer J, Surdacki A, Kruszelnicka O, Rycaj J, Godula-Stuglik U, Bode-Böger SM.

Int J Mol Sci. 2012 Nov 21;13(11):15464-74. doi: 10.3390/ijms131115464.

35.

Association of dimethylarginines and mediators of inflammation after acute ischemic stroke.

Chen S, Martens-Lobenhoffer J, Weissenborn K, Kielstein JT, Lichtinghagen R, Deb M, Li N, Tryc AB, Goldbecker A, Dong Q, Bode-Böger SM, Worthmann H.

J Neuroinflammation. 2012 Nov 17;9:251. doi: 10.1186/1742-2094-9-251.

36.

In vivo evidence that Agxt2 can regulate plasma levels of dimethylarginines in mice.

Kittel A, Maas R, König J, Mieth M, Weiss N, Jarzebska N, Hohenstein B, Martens-Lobenhoffer J, Bode-Böger SM, Rodionov RN.

Biochem Biophys Res Commun. 2013 Jan 4;430(1):84-9. doi: 10.1016/j.bbrc.2012.11.008. Epub 2012 Nov 12.

PMID:
23154179
37.

Quantification of L-arginine, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma: a step improvement in precision by stable isotope dilution mass spectrometry.

Martens-Lobenhoffer J, Bode-Böger SM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 1;904:140-3. doi: 10.1016/j.jchromb.2012.07.021. Epub 2012 Jul 31.

PMID:
22884474
38.

Decreased meropenem levels in Intensive Care Unit patients with augmented renal clearance: benefit of therapeutic drug monitoring.

Tröger U, Drust A, Martens-Lobenhoffer J, Tanev I, Braun-Dullaeus RC, Bode-Böger SM.

Int J Antimicrob Agents. 2012 Oct;40(4):370-2. doi: 10.1016/j.ijantimicag.2012.05.010. Epub 2012 Jul 11.

PMID:
22795654
39.

Asymmetrical dimethylarginine--more sensitive than NT-proBNP to diagnose heart failure in adults with congenital heart disease.

Tutarel O, Denecke A, Bode-Böger SM, Martens-Lobenhoffer J, Lovric S, Bauersachs J, Schieffer B, Westhoff-Bleck M, Kielstein JT.

PLoS One. 2012;7(3):e33795. doi: 10.1371/journal.pone.0033795. Epub 2012 Mar 21.

40.

Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines.

Vida G, Sulyok E, Ertl T, Martens-Lobenhoffer J, Bode-Böger SM.

Pediatr Int. 2012 Aug;54(4):476-9. doi: 10.1111/j.1442-200X.2012.03605.x. Epub 2012 Apr 19.

PMID:
22375624
41.

Recurrent seizures in a levetiracetam-treated patient after subarachnoid hemorrhage: a matter of enhanced renal function?

Drust A, Luchtmann M, Firsching R, Tröger U, Martens-Lobenhoffer J, Bode-Böger SM.

Epilepsy Behav. 2012 Mar;23(3):394-5. doi: 10.1016/j.yebeh.2011.12.016. Epub 2012 Feb 16. No abstract available.

PMID:
22342435
42.

Endothelial dysfunction of the peripheral vascular bed in the acute phase after ischemic stroke.

Scherbakov N, Sandek A, Martens-Lobenhoffer J, Kung T, Turhan G, Liman T, Ebinger M, von Haehling S, Bode-Böger SM, Endres M, Doehner W.

Cerebrovasc Dis. 2012;33(1):37-46. doi: 10.1159/000332809. Epub 2011 Nov 30.

PMID:
22133764
43.

Asymmetric dimethylarginine may mediate increased heat pain threshold in experimental chronic kidney disease.

Kielstein JT, Suntharalingam M, Perthel R, Rong S, Martens-Lobenhoffer J, Jäger K, Bode-Böger SM, Nave H.

Nephrol Dial Transplant. 2012 Mar;27(3):899-902. doi: 10.1093/ndt/gfr629. Epub 2011 Nov 29.

PMID:
22131232
44.

Detection and quantification of α-keto-δ-(N(G),N(G)-dimethylguanidino)valeric acid: a metabolite of asymmetric dimethylarginine.

Martens-Lobenhoffer J, Rodionov RN, Drust A, Bode-Böger SM.

Anal Biochem. 2011 Dec 15;419(2):234-40. doi: 10.1016/j.ab.2011.08.044. Epub 2011 Sep 8.

PMID:
21945966
45.

Unilateral nephrectomy causes an abrupt increase in inflammatory mediators and a simultaneous decrease in plasma ADMA: a study in living kidney donors.

Kielstein JT, Veldink H, Martens-Lobenhoffer J, Haller H, Perthel R, Lovric S, Lichtinghagen R, Kliem V, Bode-Böger SM.

Am J Physiol Renal Physiol. 2011 Nov;301(5):F1042-6. doi: 10.1152/ajprenal.00640.2010. Epub 2011 Aug 10.

46.

Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction.

Lehmann HI, Goette A, Martens-Lobenhoffer J, Hammwöhner M, Röhl FW, Bukowska A, Ghanem A, Klein HU, Bode-Böger SM.

Europace. 2011 Oct;13(10):1428-35. doi: 10.1093/europace/eur171. Epub 2011 Jul 13.

PMID:
21752828
47.

Determination of micafungin and anidulafungin in human plasma: UV- or mass spectrometric quantification?

Martens-Lobenhoffer J, Rupprecht V, Bode-Böger SM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2051-6. doi: 10.1016/j.jchromb.2011.05.033. Epub 2011 May 30.

PMID:
21680263
48.

High plasma dimethylarginine levels are associated with adverse clinical outcome after stroke.

Worthmann H, Chen S, Martens-Lobenhoffer J, Li N, Deb M, Tryc AB, Goldbecker A, Dong Q, Kielstein JT, Bode-Böger SM, Weissenborn K.

J Atheroscler Thromb. 2011;18(9):753-61. Epub 2011 May 12.

49.

Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine.

Cziráki A, Ajtay Z, Németh Á, Lenkey Z, Sulyok E, Szabados S, Alotti N, Martens-Lobenhoffer J, Szabó C, Bode-Böger SM.

Coron Artery Dis. 2011 Jun;22(4):245-52. doi: 10.1097/MCA.0b013e3283441d5c.

PMID:
21383621
50.

Symmetrical dimethylarginine outperforms CKD-EPI and MDRD-derived eGFR for the assessment of renal function in patients with adult congenital heart disease.

Tutarel O, Denecke A, Bode-Böger SM, Martens-Lobenhoffer J, Schieffer B, Westhoff-Bleck M, Kielstein JT.

Kidney Blood Press Res. 2011;34(1):41-5. doi: 10.1159/000322614. Epub 2010 Dec 16.

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