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Breakthrough in Marine Invertebrate Cell Culture: Sponge Cells Divide Rapidly in Improved Nutrient Medium.

Conkling M, Hesp K, Munroe S, Sandoval K, Martens DE, Sipkema D, Wijffels RH, Pomponi SA.

Sci Rep. 2019 Nov 21;9(1):17321. doi: 10.1038/s41598-019-53643-y.


Prevalence Of Chronic Hypercapnia In Severe Chronic Obstructive Pulmonary Disease: Data From The HOmeVent Registry.

Dreher M, Neuzeret PC, Windisch W, Martens D, Hoheisel G, Gröschel A, Woehrle H, Fetsch T, Graml A, Köhnlein T.

Int J Chron Obstruct Pulmon Dis. 2019 Oct 18;14:2377-2384. doi: 10.2147/COPD.S222803. eCollection 2019.


Early Biological Aging and Fetal Exposure to High and Low Ambient Temperature: A Birth Cohort Study.

Martens DS, Plusquin M, Cox B, Nawrot TS.

Environ Health Perspect. 2019 Nov;127(11):117001. doi: 10.1289/EHP5153. Epub 2019 Nov 6.


Continuous production of Neisseria meningitidis outer membrane vesicles.

Gerritzen MJH, Stangowez L, van de Waterbeemd B, Martens DE, Wijffels RH, Stork M.

Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9401-9410. doi: 10.1007/s00253-019-10163-z. Epub 2019 Nov 1.


Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?

Saenen ND, Martens DS, Neven KY, Alfano R, Bové H, Janssen BG, Roels HA, Plusquin M, Vrijens K, Nawrot TS.

Clin Epigenetics. 2019 Sep 17;11(1):124. doi: 10.1186/s13148-019-0688-z. Review.


Prehospital Stroke Management Optimized by Use of Clinical Scoring vs Mobile Stroke Unit for Triage of Patients With Stroke: A Randomized Clinical Trial.

Helwig SA, Ragoschke-Schumm A, Schwindling L, Kettner M, Roumia S, Kulikovski J, Keller I, Manitz M, Martens D, Grün D, Walter S, Lesmeister M, Ewen K, Brand J, Fousse M, Kauffmann J, Zimmer VC, Mathur S, Bertsch T, Guldner J, Magull-Seltenreich A, Binder A, Spüntrup E, Chatzikonstantinou A, Adam O, Kronfeld K, Liu Y, Ruckes C, Schumacher H, Grunwald IQ, Yilmaz U, Schlechtriemen T, Reith W, Fassbender K.

JAMA Neurol. 2019 Sep 3. doi: 10.1001/jamaneurol.2019.2829. [Epub ahead of print]


Prenatal and Childhood Traffic-Related Air Pollution Exposure and Telomere Length in European Children: The HELIX Project.

Clemente DBP, Vrijheid M, Martens DS, Bustamante M, Chatzi L, Danileviciute A, de Castro M, Grazuleviciene R, Gutzkow KB, Lepeule J, Maitre L, McEachan RRC, Robinson O, Schwarze PE, Tamayo I, Vafeiadi M, Wright J, Slama R, Nieuwenhuijsen M, Nawrot TS.

Environ Health Perspect. 2019 Aug;127(8):87001. doi: 10.1289/EHP4148. Epub 2019 Aug 8.


Spontaneously released Neisseria meningitidis outer membrane vesicles as vaccine platform: production and purification.

Gerritzen MJH, Salverda MLM, Martens DE, Wijffels RH, Stork M.

Vaccine. 2019 Nov 8;37(47):6978-6986. doi: 10.1016/j.vaccine.2019.01.076. Epub 2019 Aug 2.


Personal NO2 and Volatile Organic Compounds Exposure Levels are Associated with Markers of Cardiovascular Risk in Women in the Cape Town Region of South Africa.

Everson F, De Boever P, Nawrot TS, Goswami N, Mthethwa M, Webster I, Martens DS, Mashele N, Charania S, Kamau F, Strijdom H.

Int J Environ Res Public Health. 2019 Jun 28;16(13). pii: E2284. doi: 10.3390/ijerph16132284.


Exposure to Environmental Pollutants and Their Association with Biomarkers of Aging: A Multipollutant Approach.

Vriens A, Nawrot TS, Janssen BG, Baeyens W, Bruckers L, Covaci A, De Craemer S, De Henauw S, Den Hond E, Loots I, Nelen V, Schettgen T, Schoeters G, Martens DS, Plusquin M.

Environ Sci Technol. 2019 May 21;53(10):5966-5976. doi: 10.1021/acs.est.8b07141. Epub 2019 May 1.


Comparison of Cryopreservation Techniques for Cells of the Marine Sponge Dysidea etheria.

Munroe S, Martens DE, Sipkema D, Pomponi SA.

Cryo Letters. 2018 Jul/Aug;39(4):269-278.


Study on the limit of detection in MZI-based biosensor systems.

Martens D, Bienstman P.

Sci Rep. 2019 Apr 8;9(1):5767. doi: 10.1038/s41598-019-42305-8.


Sulfate depletion triggers overproduction of phospholipids and the release of outer membrane vesicles by Neisseria meningitidis.

Gerritzen MJH, Martens DE, Uittenbogaard JP, Wijffels RH, Stork M.

Sci Rep. 2019 Mar 18;9(1):4716. doi: 10.1038/s41598-019-41233-x.


Genetic algorithm as an optimization tool for the development of sponge cell culture media.

Munroe S, Sandoval K, Martens DE, Sipkema D, Pomponi SA.

In Vitro Cell Dev Biol Anim. 2019 Mar;55(3):149-158. doi: 10.1007/s11626-018-00317-0. Epub 2019 Feb 11.


Label-free real-time optical monitoring of DNA hybridization using SiN Mach-Zehnder interferometer-based integrated biosensing platform.

Murib MS, Martens D, Bienstman P.

J Biomed Opt. 2018 Dec;23(12):1-7. doi: 10.1117/1.JBO.23.12.127002.


Development of pediatric oncology supportive care indicators: Evaluation of febrile neutropenia care in the north of the Netherlands.

Ten Berg S, Loeffen EAH, van de Wetering MD, Martens DHJ, van Ede CM, Kremer LCM, Tissing WJE.

Pediatr Blood Cancer. 2019 Feb;66(2):e27504. doi: 10.1002/pbc.27504. Epub 2018 Oct 14.


High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis.

Gerritzen MJH, Maas RHW, van den Ijssel J, van Keulen L, Martens DE, Wijffels RH, Stork M.

Microb Cell Fact. 2018 Oct 3;17(1):157. doi: 10.1186/s12934-018-1007-7.


Label-Free and Real-Time Detection of Tuberculosis in Human Urine Samples Using a Nanophotonic Point-of-Care Platform.

Ramirez-Priego P, Martens D, Elamin AA, Soetaert P, Van Roy W, Vos R, Anton B, Bockstaele R, Becker H, Singh M, Bienstman P, Lechuga LM.

ACS Sens. 2018 Oct 26;3(10):2079-2086. doi: 10.1021/acssensors.8b00393. Epub 2018 Oct 16.


Sex-specific associations between telomere length and candidate miRNA expression in placenta.

Tsamou M, Martens DS, Cox B, Madhloum N, Vrijens K, Nawrot TS.

J Transl Med. 2018 Sep 12;16(1):254. doi: 10.1186/s12967-018-1627-z.


Transcriptome Analysis of CHO Cell Size Increase During a Fed-Batch Process.

Pan X, Alsayyari AA, Dalm C, Hageman JA, Wijffels RH, Martens DE.

Biotechnol J. 2019 Mar;14(3):e1800156. doi: 10.1002/biot.201800156. Epub 2018 Jul 30.


A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis.

McDonough JE, Martens DS, Tanabe N, Ahangari F, Verleden SE, Maes K, Verleden GM, Kaminski N, Hogg JC, Nawrot TS, Wuyts WA, Vanaudenaerde BM.

Respir Res. 2018 Jul 9;19(1):132. doi: 10.1186/s12931-018-0838-4.


Ageing at the level of telomeres in association to residential landscape and air pollution at home and work: a review of the current evidence.

Martens DS, Nawrot TS.

Toxicol Lett. 2018 Dec 1;298:42-52. doi: 10.1016/j.toxlet.2018.06.1213. Epub 2018 Jun 23. Review.


Transcriptome analysis for the scale-down of a CHO cell fed-batch process.

Alsayyari AA, Pan X, Dalm C, van der Veen JW, Vriezen N, Hageman JA, Wijffels RH, Martens DE.

J Biotechnol. 2018 Aug 10;279:61-72. doi: 10.1016/j.jbiotec.2018.05.012. Epub 2018 May 22.


The aging lung: tissue telomere shortening in health and disease.

Everaerts S, Lammertyn EJ, Martens DS, De Sadeleer LJ, Maes K, van Batenburg AA, Goldschmeding R, van Moorsel CHM, Dupont LJ, Wuyts WA, Vos R, Gayan-Ramirez G, Kaminski N, Hogg JC, Janssens W, Verleden GM, Nawrot TS, Verleden SE, McDonough JE, Vanaudenaerde BM.

Respir Res. 2018 May 11;19(1):95. doi: 10.1186/s12931-018-0794-z.


Retinal microcirculation and leukocyte telomere length in the general population.

Martens DS, Wei FF, Cox B, Plusquin M, Thijs L, Winckelmans E, Zhang ZY, Nawrot TS, Staessen JA.

Sci Rep. 2018 May 4;8(1):7095. doi: 10.1038/s41598-018-25165-6.


Corrigendum to "Pesticides in agricultural headwater streams in southwestern Germany and effects on macroinvertebrate populations" [Sci. Total Environ. 619-620 (1 April 2018) 638-648].

Weber G, Christmann N, Thiery AC, Martens D, Kubiniok J.

Sci Total Environ. 2018 Sep 1;635:1622-1623. doi: 10.1016/j.scitotenv.2018.04.154. Epub 2018 Apr 19. No abstract available.


Neochloris oleoabundans is worth its salt: Transcriptomic analysis under salt and nitrogen stress.

de Jaeger L, Carreres BM, Springer J, Schaap PJ, Eggink G, Martins Dos Santos VAP, Wijffels RH, Martens DE.

PLoS One. 2018 Apr 13;13(4):e0194834. doi: 10.1371/journal.pone.0194834. eCollection 2018.


Author Correction: Mother's Pre-pregnancy BMI and Placental Candidate miRNAs: Findings from the ENVIRONAGE Birth Cohort.

Tsamou M, Martens DS, Winckelmans E, Madhloum N, Cox B, Gyselaers W, Nawrot TS, Vrijens K.

Sci Rep. 2018 Apr 11;8(1):6063. doi: 10.1038/s41598-018-24090-y.


Experience With Prehospital Damage Control Capability in Modern Conflict: Results From Surgical Resuscitation Team Use.

DuBose JJ, Martens D, Frament C, Haque I, Telian S, Benson PJ.

J Spec Oper Med. Winter 2017;17(4):68-71.


Environmental mineralization of caffeine micro-pollutant by Fe-MFI zeolites.

Motuzas J, Drobek M, Martens DL, Vallicari C, Julbe A, Diniz da Costa JC.

Environ Sci Pollut Res Int. 2018 Feb;25(4):3628-3635. doi: 10.1007/s11356-017-0530-0. Epub 2017 Nov 21.


Telomere tracking from birth to adulthood and residential traffic exposure.

Bijnens EM, Zeegers MP, Derom C, Martens DS, Gielen M, Hageman GJ, Plusquin M, Thiery E, Vlietinck R, Nawrot TS.

BMC Med. 2017 Nov 21;15(1):205. doi: 10.1186/s12916-017-0964-8.


Pesticides in agricultural headwater streams in southwestern Germany and effects on macroinvertebrate populations.

Weber G, Christmann N, Thiery AC, Martens D, Kubiniok J.

Sci Total Environ. 2018 Apr 1;619-620:638-648. doi: 10.1016/j.scitotenv.2017.11.155. Epub 2017 Nov 29. Erratum in: Sci Total Environ. 2018 Apr 19;:.


Prehospital Computed Tomography Angiography in Acute Stroke Management.

Kettner M, Helwig SA, Ragoschke-Schumm A, Schwindling L, Roumia S, Keller I, Martens D, Kulikovski J, Manitz M, Lesmeister M, Walter S, Grunwald IQ, Schlechtriemen T, Reith W, Fassbender K.

Cerebrovasc Dis. 2017;44(5-6):338-343. doi: 10.1159/000484097. Epub 2017 Oct 31.


Prenatal Air Pollution and Newborns' Predisposition to Accelerated Biological Aging.

Martens DS, Cox B, Janssen BG, Clemente DBP, Gasparrini A, Vanpoucke C, Lefebvre W, Roels HA, Plusquin M, Nawrot TS.

JAMA Pediatr. 2017 Dec 1;171(12):1160-1167. doi: 10.1001/jamapediatrics.2017.3024.


Metabolic characterization of a CHO cell size increase phase in fed-batch cultures.

Pan X, Dalm C, Wijffels RH, Martens DE.

Appl Microbiol Biotechnol. 2017 Nov;101(22):8101-8113. doi: 10.1007/s00253-017-8531-y. Epub 2017 Sep 26.


Cord blood eicosanoid signatures and newborn gestational age.

Gouveia-Figueira S, Martens DS, Nawrot TS, Nording ML.

Prostaglandins Other Lipid Mediat. 2017 Nov;133:123-127. doi: 10.1016/j.prostaglandins.2017.07.003. Epub 2017 Jul 20.


High throughput nanoparticle tracking analysis for monitoring outer membrane vesicle production.

Gerritzen MJH, Martens DE, Wijffels RH, Stork M.

J Extracell Vesicles. 2017 Jun 19;6(1):1333883. doi: 10.1080/20013078.2017.1333883. eCollection 2017.


Mother's Pre-pregnancy BMI and Placental Candidate miRNAs: Findings from the ENVIRONAGE Birth Cohort.

Tsamou M, Martens DS, Winckelmans E, Madhloum N, Cox B, Gyselaers W, Nawrot TS, Vrijens K.

Sci Rep. 2017 Jul 17;7(1):5548. doi: 10.1038/s41598-017-04026-8. Erratum in: Sci Rep. 2018 Apr 11;8(1):6063.


Ultrasound Guidance Does Not Improve the Results of Shock Wave for Plantar Fasciitis or Calcific Achilles Tendinopathy: A Randomized Control Trial.

Njawaya MM, Moses B, Martens D, Orchard JJ, Driscoll T, Negrine J, Orchard JW.

Clin J Sport Med. 2018 Jan;28(1):21-27. doi: 10.1097/JSM.0000000000000430.


Gene silencing of stearoyl-ACP desaturase enhances the stearic acid content in Chlamydomonas reinhardtii.

de Jaeger L, Springer J, Wolbert EJH, Martens DE, Eggink G, Wijffels RH.

Bioresour Technol. 2017 Dec;245(Pt B):1616-1626. doi: 10.1016/j.biortech.2017.06.128. Epub 2017 Jun 30.


Cord plasma insulin and in utero exposure to ambient air pollution.

Madhloum N, Janssen BG, Martens DS, Saenen ND, Bijnens E, Gyselaers W, Penders J, Vanpoucke C, Lefebvre W, Plusquin M, Nawrot TS.

Environ Int. 2017 Aug;105:126-132. doi: 10.1016/j.envint.2017.05.012. Epub 2017 May 22.


[Homöopathisch-phytotherapeutische Behandlung des Reizdarmsyndroms mit Magen-Darm-Entoxin N®: Eine Anwendungsbeobachtung].

Märtens D, Range N, Günnewich N, Gruber N, Schmidt S.

Complement Med Res. 2017;24(3):147-152. doi: 10.1159/000477090. Epub 2017 May 24. German.


Bioengineering bacterial outer membrane vesicles as vaccine platform.

Gerritzen MJH, Martens DE, Wijffels RH, van der Pol L, Stork M.

Biotechnol Adv. 2017 Sep;35(5):565-574. doi: 10.1016/j.biotechadv.2017.05.003. Epub 2017 May 15. Review.


The influence of day/night cycles on biomass yield and composition of Neochloris oleoabundans.

de Winter L, Cabanelas ITD, Martens DE, Wijffels RH, Barbosa MJ.

Biotechnol Biofuels. 2017 Apr 22;10:104. doi: 10.1186/s13068-017-0762-8. eCollection 2017.


Dynamics of triacylglycerol and EPA production in Phaeodactylum tricornutum under nitrogen starvation at different light intensities.

Remmers IM, Martens DE, Wijffels RH, Lamers PP.

PLoS One. 2017 Apr 12;12(4):e0175630. doi: 10.1371/journal.pone.0175630. eCollection 2017.


Draft Genome Sequence of the Oleaginous Green Alga Tetradesmus obliquus UTEX 393.

Carreres BM, de Jaeger L, Springer J, Barbosa MJ, Breuer G, van den End EJ, Kleinegris DM, Schäffers I, Wolbert EJ, Zhang H, Lamers PP, Draaisma RB, Martins Dos Santos VA, Wijffels RH, Eggink G, Schaap PJ, Martens DE.

Genome Announc. 2017 Jan 19;5(3). pii: e01449-16. doi: 10.1128/genomeA.01449-16.


Cohort Profile: The ENVIRonmental influence ON early AGEing (ENVIRONAGE): a birth cohort study.

Janssen BG, Madhloum N, Gyselaers W, Bijnens E, Clemente DB, Cox B, Hogervorst J, Luyten L, Martens DS, Peusens M, Plusquin M, Provost EB, Roels HA, Saenen ND, Tsamou M, Vriens A, Winckelmans E, Vrijens K, Nawrot TS.

Int J Epidemiol. 2017 Oct 1;46(5):1386-1387m. doi: 10.1093/ije/dyw269. No abstract available. Erratum in: Int J Epidemiol. 2017 Oct 1;46(5):1387m.


Selection of chemically defined media for CHO cell fed-batch culture processes.

Pan X, Streefland M, Dalm C, Wijffels RH, Martens DE.

Cytotechnology. 2017 Feb;69(1):39-56. doi: 10.1007/s10616-016-0036-5. Epub 2016 Nov 29.


Neonatal Cord Blood Oxylipins and Exposure to Particulate Matter in the Early-Life Environment: An ENVIRONAGE Birth Cohort Study.

Martens DS, Gouveia S, Madhloum N, Janssen BG, Plusquin M, Vanpoucke C, Lefebvre W, Forsberg B, Nording M, Nawrot TS.

Environ Health Perspect. 2017 Apr;125(4):691-698. doi: 10.1289/EHP291. Epub 2016 Nov 4.


Maternal pre-pregnancy body mass index and newborn telomere length.

Martens DS, Plusquin M, Gyselaers W, De Vivo I, Nawrot TS.

BMC Med. 2016 Oct 18;14(1):148.

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