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Items: 42

1.

Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination.

Lennon S, Oweida A, Milner D, Phan AV, Bhatia S, Van Court B, Darragh L, Mueller AC, Raben D, Martínez-Torrecuadrada JL, Pitts TM, Somerset H, Jordan KR, Hansen KC, Williams J, Messersmith WA, Schulick RD, Owens P, Goodman KA, Karam SD.

Clin Cancer Res. 2019 Jun 1;25(11):3352-3365. doi: 10.1158/1078-0432.CCR-18-2811. Epub 2019 Apr 3.

PMID:
30944125
2.

Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies.

Toledo RA, Garralda E, Mitsi M, Pons T, Monsech J, Vega E, Otero Á, Albarran MI, Baños N, Durán Y, Bonilla V, Sarno F, Camacho-Artacho M, Sanchez-Perez T, Perea S, Álvarez R, De Martino A, Lietha D, Blanco-Aparicio C, Cubillo A, Domínguez O, Martínez-Torrecuadrada JL, Hidalgo M.

Clin Cancer Res. 2018 Aug 1;24(15):3550-3559. doi: 10.1158/1078-0432.CCR-18-0103. Epub 2018 Mar 27.

3.

Display of the Albumin-Binding Domain in the Envelope Improves Lentiviral Vector Bioavailability.

Garaulet G, Lazcano JJ, Alarcón H, de Frutos S, Martínez-Torrecuadrada JL, Rodríguez A.

Hum Gene Ther Methods. 2017 Dec;28(6):340-351. doi: 10.1089/hgtb.2017.057.

PMID:
29160106
4.

Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine.

Olmeda D, Cerezo-Wallis D, Riveiro-Falkenbach E, Pennacchi PC, Contreras-Alcalde M, Ibarz N, Cifdaloz M, Catena X, Calvo TG, Cañón E, Alonso-Curbelo D, Suarez J, Osterloh L, Graña O, Mulero F, Megías D, Cañamero M, Martínez-Torrecuadrada JL, Mondal C, Di Martino J, Lora D, Martinez-Corral I, Bravo-Cordero JJ, Muñoz J, Puig S, Ortiz-Romero P, Rodriguez-Peralto JL, Ortega S, Soengas MS.

Nature. 2017 Jun 28;546(7660):676-680. doi: 10.1038/nature22977.

5.

Sinusoidal ephrin receptor EPHB4 controls hematopoietic progenitor cell mobilization from bone marrow.

Kwak H, Salvucci O, Weigert R, Martinez-Torrecuadrada JL, Henkemeyer M, Poulos MG, Butler JM, Tosato G.

J Clin Invest. 2016 Dec 1;126(12):4554-4568. doi: 10.1172/JCI87848. Epub 2016 Nov 7.

6.

Molecular Architecture of Full-length TRF1 Favors Its Interaction with DNA.

Boskovic J, Martinez-Gago J, Mendez-Pertuz M, Buscato A, Martinez-Torrecuadrada JL, Blasco MA.

J Biol Chem. 2016 Oct 7;291(41):21829-21835. Epub 2016 Aug 25.

7.

Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas.

de Lucas AG, Schuhmacher AJ, Oteo M, Romero E, Cámara JA, de Martino A, Arroyo AG, Morcillo MÁ, Squatrito M, Martinez-Torrecuadrada JL, Mulero F.

PLoS One. 2016 Jul 27;11(7):e0158634. doi: 10.1371/journal.pone.0158634. eCollection 2016.

8.

Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome.

Pucheta-Martinez E, D'Amelio N, Lelli M, Martinez-Torrecuadrada JL, Sudol M, Saladino G, Gervasio FL.

Sci Rep. 2016 Jul 26;6:30293. doi: 10.1038/srep30293.

9.

Towards a Molecular Understanding of the Link between Imatinib Resistance and Kinase Conformational Dynamics.

Lovera S, Morando M, Pucheta-Martinez E, Martinez-Torrecuadrada JL, Saladino G, Gervasio FL.

PLoS Comput Biol. 2015 Nov 25;11(11):e1004578. doi: 10.1371/journal.pcbi.1004578. eCollection 2015 Nov.

10.

CSF1R Protein Expression in Reactive Lymphoid Tissues and Lymphoma: Its Relevance in Classical Hodgkin Lymphoma.

Martín-Moreno AM, Roncador G, Maestre L, Mata E, Jiménez S, Martínez-Torrecuadrada JL, Reyes-García AI, Rubio C, Tomás JF, Estévez M, Pulford K, Piris MA, García JF.

PLoS One. 2015 Jun 12;10(6):e0125203. doi: 10.1371/journal.pone.0125203. eCollection 2015.

11.

NOTCH pathway inactivation promotes bladder cancer progression.

Maraver A, Fernandez-Marcos PJ, Cash TP, Mendez-Pertuz M, Dueñas M, Maietta P, Martinelli P, Muñoz-Martin M, Martínez-Fernández M, Cañamero M, Roncador G, Martinez-Torrecuadrada JL, Grivas D, de la Pompa JL, Valencia A, Paramio JM, Real FX, Serrano M.

J Clin Invest. 2015 Feb;125(2):824-30. doi: 10.1172/JCI78185. Epub 2015 Jan 9.

12.

The C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins.

Barreira M, Fabbiano S, Couceiro JR, Torreira E, Martínez-Torrecuadrada JL, Montoya G, Llorca O, Bustelo XR.

Sci Signal. 2014 Apr 15;7(321):ra35. doi: 10.1126/scisignal.2004993.

PMID:
24736456
13.

Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth.

Abéngozar MA, de Frutos S, Ferreiro S, Soriano J, Perez-Martinez M, Olmeda D, Marenchino M, Cañamero M, Ortega S, Megias D, Rodriguez A, Martínez-Torrecuadrada JL.

Blood. 2012 May 10;119(19):4565-76. doi: 10.1182/blood-2011-09-380006. Epub 2012 Mar 23.

PMID:
22446484
14.

Differential protein expression on the cell surface of colorectal cancer cells associated to tumor metastasis.

Luque-García JL, Martínez-Torrecuadrada JL, Epifano C, Cañamero M, Babel I, Casal JI.

Proteomics. 2010 Mar;10(5):940-52. doi: 10.1002/pmic.200900441.

PMID:
20049862
15.

Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays.

Babel I, Barderas R, Díaz-Uriarte R, Martínez-Torrecuadrada JL, Sánchez-Carbayo M, Casal JI.

Mol Cell Proteomics. 2009 Oct;8(10):2382-95. doi: 10.1074/mcp.M800596-MCP200. Epub 2009 Jul 28.

16.

Identification of MNDA as a new marker for nodal marginal zone lymphoma.

Kanellis G, Roncador G, Arribas A, Mollejo M, Montes-Moreno S, Maestre L, Campos-Martin Y, Ríos Gonzalez JL, Martinez-Torrecuadrada JL, Sanchez-Verde L, Pajares R, Cigudosa JC, Martin MC, Piris MA.

Leukemia. 2009 Oct;23(10):1847-57. doi: 10.1038/leu.2009.108. Epub 2009 May 28.

PMID:
19474799
17.

Differential phosphorylation patterns between the Cyclin-A2/CDK2 complex and their monomers.

Casado-Vela J, Martínez-Torrecuadrada JL, Casal JI.

Protein Expr Purif. 2009 Jul;66(1):15-21. doi: 10.1016/j.pep.2009.02.007. Epub 2009 Feb 20.

PMID:
19233286
18.

Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis.

Martínez-Torrecuadrada JL, Cheung LH, López-Serra P, Barderas R, Cañamero M, Ferreiro S, Rosenblum MG, Casal JI.

Mol Cancer Ther. 2008 Apr;7(4):862-73. doi: 10.1158/1535-7163.MCT-07-0394.

19.

Designing antibodies for the inhibition of gastrin activity in tumoral cell lines.

Barderas R, Shochat S, Timmerman P, Hollestelle MJ, Martínez-Torrecuadrada JL, Höppener JW, Altschuh D, Meloen R, Casal JI.

Int J Cancer. 2008 May 15;122(10):2351-9. doi: 10.1002/ijc.23395.

20.

Gcet1 (centerin), a highly restricted marker for a subset of germinal center-derived lymphomas.

Montes-Moreno S, Roncador G, Maestre L, Martínez N, Sanchez-Verde L, Camacho FI, Cannata J, Martinez-Torrecuadrada JL, Shen Y, Chan WC, Piris MA.

Blood. 2008 Jan 1;111(1):351-8. Epub 2007 Sep 26.

PMID:
17898315
21.

Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis.

Madoz-Gúrpide J, López-Serra P, Martínez-Torrecuadrada JL, Sánchez L, Lombardía L, Casal JI.

Mol Cell Proteomics. 2006 Aug;5(8):1471-83. Epub 2006 May 29.

22.

Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level.

Roncador G, Brown PJ, Maestre L, Hue S, Martínez-Torrecuadrada JL, Ling KL, Pratap S, Toms C, Fox BC, Cerundolo V, Powrie F, Banham AH.

Eur J Immunol. 2005 Jun;35(6):1681-91.

23.

An efficient expression system for the production of functionally active human LKB1.

Martínez-Torrecuadrada JL, Romero S, Núñez A, Alfonso P, Sánchez-Céspedes M, Casal JI.

J Biotechnol. 2005 Jan 12;115(1):23-34.

PMID:
15607222
24.

Structure-dependent efficacy of infectious bursal disease virus (IBDV) recombinant vaccines.

Martinez-Torrecuadrada JL, Saubi N, Pagès-Manté A, Castón JR, Espuña E, Casal JI.

Vaccine. 2003 Jul 4;21(23):3342-50.

PMID:
12804866
25.

Structure-dependent efficacy of infectious bursal disease virus (IBDV) recombinant vaccines.

Martinez-Torrecuadrada JL, Saubi N, Pagès-Manté A, Castón JR, Espuña E, Casal JI.

Vaccine. 2003 May 16;21(17-18):1952-60.

PMID:
12706682
26.

Identification of immunogenic hot spots within plum pox potyvirus capsid protein for efficient antigen presentation.

Fernández-Fernández MR, Martínez-Torrecuadrada JL, Roncal F, Domínguez E, García JA.

J Virol. 2002 Dec;76(24):12646-53.

27.

Characterization of the immune response to canine parvovirus induced by vaccination with chimaeric plant viruses.

Nicholas BL, Brennan FR, Martinez-Torrecuadrada JL, Casal JI, Hamilton WD, Wakelin D.

Vaccine. 2002 Jun 21;20(21-22):2727-34.

PMID:
12034099
28.

C terminus of infectious bursal disease virus major capsid protein VP2 is involved in definition of the T number for capsid assembly.

Castón JR, Martínez-Torrecuadrada JL, Maraver A, Lombardo E, Rodríguez JF, Casal JI, Carrascosa JL.

J Virol. 2001 Nov;75(22):10815-28.

29.

Definition of neutralizing sites on African horse sickness virus serotype 4 VP2 at the level of peptides.

Martínez-Torrecuadrada JL, Langeveld JP, Meloen RH, Casal JI.

J Gen Virol. 2001 Oct;82(Pt 10):2415-24.

PMID:
11562535
30.

Inactivated recombinant plant virus protects dogs from a lethal challenge with canine parvovirus.

Langeveld JP, Brennan FR, Martínez-Torrecuadrada JL, Jones TD, Boshuizen RS, Vela C, Casal JI, Kamstrup S, Dalsgaard K, Meloen RH, Bendig MM, Hamilton WD.

Vaccine. 2001 Jun 14;19(27):3661-70.

PMID:
11395200
31.

High-yield expression of a viral peptide vaccine in transgenic plants.

Gil F, Brun A, Wigdorovitz A, Catalá R, Martínez-Torrecuadrada JL, Casal I, Salinas J, Borca MV, Escribano JM.

FEBS Lett. 2001 Jan 12;488(1-2):13-7.

32.

Different architectures in the assembly of infectious bursal disease virus capsid proteins expressed in insect cells.

Martinez-Torrecuadrada JL, Castón JR, Castro M, Carrascosa JL, Rodriguez JF, Casal JI.

Virology. 2000 Dec 20;278(2):322-31.

33.

Antigenic properties and diagnostic potential of baculovirus-expressed infectious bursal disease virus proteins VPX and VP3.

Martínez-Torrecuadrada JL, Lázaro B, Rodriguez JF, Casal JI.

Clin Diagn Lab Immunol. 2000 Jul;7(4):645-51.

34.

Minor displacements in the insertion site provoke major differences in the induction of antibody responses by chimeric parvovirus-like particles.

Rueda P, Hurtado A, del Barrio M, Martínez-Torrecuadrada JL, Kamstrup S, Leclerc C, Casal JI.

Virology. 1999 Oct 10;263(1):89-99.

35.

Engineering parvovirus-like particles for the induction of B-cell, CD4(+) and CTL responses.

Rueda P, Martínez-Torrecuadrada JL, Sarraseca J, Sedlik C, del Barrio M, Hurtado A, Leclerc C, Casal JI.

Vaccine. 1999 Sep;18(3-4):325-32.

PMID:
10506659
36.

Antigenic profile of African horse sickness virus serotype 4 VP5 and identification of a neutralizing epitope shared with bluetongue virus and epizootic hemorrhagic disease virus.

Martínez-Torrecuadrada JL, Langeveld JP, Venteo A, Sanz A, Dalsgaard K, Hamilton WD, Meloen RH, Casal JI.

Virology. 1999 May 10;257(2):449-59.

37.

Antigenic structure of the capsid protein of rabbit haemorrhagic disease virus.

Martínez-Torrecuadrada JL, Cortés E, Vela C, Langeveld JP, Meloen RH, Dalsgaard K, Hamilton WD, Casal JI.

J Gen Virol. 1998 Aug;79 ( Pt 8):1901-9.

PMID:
9714238
38.

Development of an antigen presentation system based on plum pox potyvirus.

Fernández-Fernández MR, Martínez-Torrecuadrada JL, Casal JI, García JA.

FEBS Lett. 1998 May 8;427(2):229-35.

39.

Serologic markers in early stages of African horse sickness virus infection.

Martínez-Torrecuadrada JL, Díaz-Laviada M, Roy P, Sánchez C, Vela C, Sánchez-Vizcaíno JM, Casal JI.

J Clin Microbiol. 1997 Feb;35(2):531-5.

40.

Full protection against African horsesickness (AHS) in horses induced by baculovirus-derived AHS virus serotype 4 VP2, VP5 and VP7.

Martínez-Torrecuadrada JL, Díaz-Laviada M, Roy P, Sánchez C, Vela C, Sánchez-Vizcaíno JM, Casal JI.

J Gen Virol. 1996 Jun;77 ( Pt 6):1211-21.

PMID:
8683209
41.

Identification of a linear neutralization domain in the protein VP2 of African horse sickness virus.

Martínez-Torrecuadrada JL, Casal JI.

Virology. 1995 Jul 10;210(2):391-9.

42.

Expression and characterization of the two outer capsid proteins of African horsesickness virus: the role of VP2 in virus neutralization.

Martinez-Torrecuadrada JL, Iwata H, Venteo A, Casal I, Roy P.

Virology. 1994 Jul;202(1):348-59.

PMID:
8009847

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