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Items: 1 to 50 of 138

1.

A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.

Cubitt B, Ortiz-Riano E, Cheng BY, Kim YJ, Yeh CD, Chen CZ, Southall NOE, Zheng W, Martinez-Sobrido L, de la Torre JC.

Antiviral Res. 2019 Nov 28;173:104667. doi: 10.1016/j.antiviral.2019.104667. [Epub ahead of print]

PMID:
31786250
2.

A live-attenuated influenza vaccine (LAIV) elicits enhanced heterologous protection when the internal genes of the vaccine are matched to the challenge virus.

Smith A, Rodriguez L, Ghouayel ME, Nogales A, Chamberlain JM, Sortino K, Reilly E, Feng C, Topham DJ, Martínez-Sobrido L, Dewhurst S.

J Virol. 2019 Nov 20. pii: JVI.01065-19. doi: 10.1128/JVI.01065-19. [Epub ahead of print]

3.

Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines.

Rodriguez L, Blanco-Lobo P, Reilly EC, Maehigashi T, Nogales A, Smith A, Topham DJ, Dewhurst S, Kim B, Martínez-Sobrido L.

Viruses. 2019 Oct 10;11(10). pii: E928. doi: 10.3390/v11100928.

4.

A Bivalent Live-Attenuated Vaccine for the Prevention of Equine Influenza Virus.

Blanco-Lobo P, Rodriguez L, Reedy S, Oladunni FS, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L.

Viruses. 2019 Oct 11;11(10). pii: E933. doi: 10.3390/v11100933.

5.

Influenza Viruses in Mice: Deep Sequencing Analysis of Serial Passage and Effects of Sialic Acid Structural Variation.

Wasik BR, Voorhees IEH, Barnard KN, Alford-Lawrence BK, Weichert WS, Hood G, Nogales A, Martínez-Sobrido L, Holmes EC, Parrish CR.

J Virol. 2019 Nov 13;93(23). pii: e01039-19. doi: 10.1128/JVI.01039-19. Print 2019 Dec 1.

PMID:
31511393
6.

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection.

Chiem K, Rangel-Moreno J, Nogales A, Martinez-Sobrido L.

J Vis Exp. 2019 Aug 14;(150). doi: 10.3791/59890.

PMID:
31475986
7.

Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication.

DeDiego ML, Nogales A, Martinez-Sobrido L, Topham DJ.

MBio. 2019 Aug 27;10(4). pii: e01839-19. doi: 10.1128/mBio.01839-19.

8.

Novel Functions of IFI44L as a Feedback Regulator of Host Antiviral Responses.

DeDiego ML, Martinez-Sobrido L, Topham DJ.

J Virol. 2019 Oct 15;93(21). pii: e01159-19. doi: 10.1128/JVI.01159-19. Print 2019 Nov 1.

PMID:
31434731
9.

Onward transmission of viruses: how do viruses emerge to cause epidemics after spillover?

Wasik BR, de Wit E, Munster V, Lloyd-Smith JO, Martinez-Sobrido L, Parrish CR.

Philos Trans R Soc Lond B Biol Sci. 2019 Sep 30;374(1782):20190017. doi: 10.1098/rstb.2019.0017. Epub 2019 Aug 12.

PMID:
31401954
10.

Peptides Derived from the Tight Junction Protein CLDN1 Disrupt the Skin Barrier and Promote Responsiveness to an Epicutaneous Vaccine.

Brewer MG, Anderson EA, Pandya RP, De Benedetto A, Yoshida T, Hilimire TA, Martinez-Sobrido L, Beck LA, Miller BL.

J Invest Dermatol. 2019 Aug 2. pii: S0022-202X(19)32682-X. doi: 10.1016/j.jid.2019.06.145. [Epub ahead of print]

PMID:
31381894
11.

Rescue of Recombinant Zika Virus from a Bacterial Artificial Chromosome cDNA Clone.

Ávila-Pérez G, Park JG, Nogales A, Almazán F, Martínez-Sobrido L.

J Vis Exp. 2019 Jun 24;(148). doi: 10.3791/59537.

PMID:
31282877
12.

In vivo analysis of influenza A mRNA secondary structures identifies critical regulatory motifs.

Simon LM, Morandi E, Luganini A, Gribaudo G, Martinez-Sobrido L, Turner DH, Oliviero S, Incarnato D.

Nucleic Acids Res. 2019 Jul 26;47(13):7003-7017. doi: 10.1093/nar/gkz318.

13.

Potent Inhibition of Zika Virus Replication by Aurintricarboxylic Acid.

Park JG, Ávila-Pérez G, Madere F, Hilimire TA, Nogales A, Almazán F, Martínez-Sobrido L.

Front Microbiol. 2019 Apr 12;10:718. doi: 10.3389/fmicb.2019.00718. eCollection 2019.

14.

Aryl and Arylalkyl Substituted 3-Hydroxypyridin-2(1H)-ones: Synthesis and Evaluation as Inhibitors of Influenza A Endonuclease.

Sagong HY, Bauman JD, Nogales A, Martínez-Sobrido L, Arnold E, LaVoie EJ.

ChemMedChem. 2019 Jun 18;14(12):1204-1223. doi: 10.1002/cmdc.201900084. Epub 2019 May 14.

PMID:
30983160
15.

New Advances on Zika Virus Research.

Martinez-Sobrido L, Almazán F.

Viruses. 2019 Mar 14;11(3). pii: E258. doi: 10.3390/v11030258.

16.

A Novel Fluorescent and Bioluminescent Bireporter Influenza A Virus To Evaluate Viral Infections.

Nogales A, Ávila-Pérez G, Rangel-Moreno J, Chiem K, DeDiego ML, Martínez-Sobrido L.

J Virol. 2019 May 1;93(10). pii: e00032-19. doi: 10.1128/JVI.00032-19. Print 2019 May 15.

17.

Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells.

Piepenbrink MS, Nogales A, Basu M, Fucile CF, Liesveld JL, Keefer MC, Rosenberg AF, Martinez-Sobrido L, Kobie JJ.

MBio. 2019 Mar 12;10(2). pii: e00066-19. doi: 10.1128/mBio.00066-19.

18.

Novel Approaches for The Development of Live Attenuated Influenza Vaccines.

Blanco-Lobo P, Nogales A, Rodríguez L, Martínez-Sobrido L.

Viruses. 2019 Feb 22;11(2). pii: E190. doi: 10.3390/v11020190. Review.

19.

Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus.

Tesini BL, Kanagaiah P, Wang J, Hahn M, Halliley JL, Chaves FA, Nguyen PQT, Nogales A, DeDiego ML, Anderson CS, Ellebedy AH, Strohmeier S, Krammer F, Yang H, Bandyopadhyay S, Ahmed R, Treanor JJ, Martinez-Sobrido L, Golding H, Khurana S, Zand MS, Topham DJ, Sangster MY.

J Virol. 2019 Apr 3;93(8). pii: e00169-19. doi: 10.1128/JVI.00169-19. Print 2019 Apr 15.

20.

Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins.

Nogales A, Martinez-Sobrido L, Topham DJ, DeDiego ML.

Viruses. 2018 Dec 12;10(12). pii: E708. doi: 10.3390/v10120708. Review.

21.

Identification of Amino Acid Residues Responsible for Inhibition of Host Gene Expression by Influenza A H9N2 NS1 Targeting of CPSF30.

Rodriguez L, Nogales A, Iqbal M, Perez DR, Martinez-Sobrido L.

Front Microbiol. 2018 Oct 24;9:2546. doi: 10.3389/fmicb.2018.02546. eCollection 2018.

22.

Reverse Genetic Approaches for the Generation of Recombinant Zika Virus.

Ávila-Pérez G, Nogales A, Martín V, Almazán F, Martínez-Sobrido L.

Viruses. 2018 Oct 31;10(11). pii: E597. doi: 10.3390/v10110597. Review.

23.

Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine.

Martínez-Sobrido L, Peersen O, Nogales A.

Viruses. 2018 Oct 15;10(10). pii: E560. doi: 10.3390/v10100560. Review.

24.

An Alanine-to-Valine Substitution in the Residue 175 of Zika Virus NS2A Protein Affects Viral RNA Synthesis and Attenuates the Virus In Vivo.

Márquez-Jurado S, Nogales A, Ávila-Pérez G, Iborra FJ, Martínez-Sobrido L, Almazán F.

Viruses. 2018 Oct 7;10(10). pii: E547. doi: 10.3390/v10100547.

25.

Functional Evolution of the 2009 Pandemic H1N1 Influenza Virus NS1 and PA in Humans.

Nogales A, Martinez-Sobrido L, Chiem K, Topham DJ, DeDiego ML.

J Virol. 2018 Sep 12;92(19). pii: e01206-18. doi: 10.1128/JVI.01206-18. Print 2018 Oct 1.

26.

Crowd on a Chip: Label-Free Human Monoclonal Antibody Arrays for Serotyping Influenza.

Zhang H, Henry C, Anderson CS, Nogales A, DeDiego ML, Bucukovski J, Martinez-Sobrido L, Wilson PC, Topham DJ, Miller BL.

Anal Chem. 2018 Aug 7;90(15):9583-9590. doi: 10.1021/acs.analchem.8b02479. Epub 2018 Jul 20.

27.

TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus.

Brouillette RB, Phillips EK, Patel R, Mahauad-Fernandez W, Moller-Tank S, Rogers KJ, Dillard JA, Cooney AL, Martinez-Sobrido L, Okeoma C, Maury W.

J Virol. 2018 Jul 31;92(16). pii: e00093-18. doi: 10.1128/JVI.00093-18. Print 2018 Aug 15.

28.

Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.

Wang J, Hilchey SP, DeDiego M, Perry S, Hyrien O, Nogales A, Garigen J, Amanat F, Huertas N, Krammer F, Martinez-Sobrido L, Topham DJ, Treanor JJ, Sangster MY, Zand MS.

PLoS One. 2018 Apr 11;13(4):e0193680. doi: 10.1371/journal.pone.0193680. eCollection 2018.

29.

A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody.

Nogales A, Piepenbrink MS, Wang J, Ortega S, Basu M, Fucile CF, Treanor JJ, Rosenberg AF, Zand MS, Keefer MC, Martinez-Sobrido L, Kobie JJ.

Sci Rep. 2018 Mar 12;8(1):4374. doi: 10.1038/s41598-018-22307-8.

30.

Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage.

Duffney PF, McCarthy CE, Nogales A, Thatcher TH, Martinez-Sobrido L, Phipps RP, Sime PJ.

Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L505-L513. doi: 10.1152/ajplung.00406.2017. Epub 2017 Dec 14.

31.

Development of a novel equine influenza virus live-attenuated vaccine.

Rodriguez L, Reedy S, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L.

Virology. 2018 Mar;516:76-85. doi: 10.1016/j.virol.2018.01.005. Epub 2018 Jan 11.

32.

Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1.

Chauché C, Nogales A, Zhu H, Goldfarb D, Ahmad Shanizza AI, Gu Q, Parrish CR, Martínez-Sobrido L, Marshall JF, Murcia PR.

J Virol. 2018 Feb 12;92(5). pii: e01875-17. doi: 10.1128/JVI.01875-17. Print 2018 Mar 1.

33.

Antigenicity of the 2015-2016 seasonal H1N1 human influenza virus HA and NA proteins.

Clark AM, DeDiego ML, Anderson CS, Wang J, Yang H, Nogales A, Martinez-Sobrido L, Zand MS, Sangster MY, Topham DJ.

PLoS One. 2017 Nov 16;12(11):e0188267. doi: 10.1371/journal.pone.0188267. eCollection 2017.

34.

Influenza A Virus Studies in a Mouse Model of Infection.

Rodriguez L, Nogales A, Martínez-Sobrido L.

J Vis Exp. 2017 Sep 7;(127). doi: 10.3791/55898.

35.

Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo.

DiPiazza A, Nogales A, Poulton N, Wilson PC, Martínez-Sobrido L, Sant AJ.

Sci Rep. 2017 Sep 7;7(1):10857. doi: 10.1038/s41598-017-11313-x.

36.

The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression.

Nogales A, Chauché C, DeDiego ML, Topham DJ, Parrish CR, Murcia PR, Martínez-Sobrido L.

J Virol. 2017 Oct 27;91(22). pii: e00877-17. doi: 10.1128/JVI.00877-17. Print 2017 Nov 15.

37.

Oxygen-dependent changes in lung development do not affect epithelial infection with influenza A virus.

Domm W, Yee M, Misra RS, Gelein R, Nogales A, Martinez-Sobrido L, O'Reilly MA.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L940-L949. doi: 10.1152/ajplung.00203.2017. Epub 2017 Aug 10.

38.

A bivalent live-attenuated influenza vaccine for the control and prevention of H3N8 and H3N2 canine influenza viruses.

Rodriguez L, Nogales A, Murcia PR, Parrish CR, Martínez-Sobrido L.

Vaccine. 2017 Aug 3;35(34):4374-4381. doi: 10.1016/j.vaccine.2017.06.060. Epub 2017 Jul 11.

PMID:
28709557
39.

Functional Evolution of Influenza Virus NS1 Protein in Currently Circulating Human 2009 Pandemic H1N1 Viruses.

Clark AM, Nogales A, Martinez-Sobrido L, Topham DJ, DeDiego ML.

J Virol. 2017 Aug 10;91(17). pii: e00721-17. doi: 10.1128/JVI.00721-17. Print 2017 Sep 1.

40.

Interplay of PA-X and NS1 Proteins in Replication and Pathogenesis of a Temperature-Sensitive 2009 Pandemic H1N1 Influenza A Virus.

Nogales A, Rodriguez L, DeDiego ML, Topham DJ, Martínez-Sobrido L.

J Virol. 2017 Aug 10;91(17). pii: e00720-17. doi: 10.1128/JVI.00720-17. Print 2017 Sep 1.

41.

Plasmid-Based Reverse Genetics of Influenza A Virus.

Perez DR, Angel M, Gonzalez-Reiche AS, Santos J, Obadan A, Martinez-Sobrido L.

Methods Mol Biol. 2017;1602:251-273. doi: 10.1007/978-1-4939-6964-7_16.

PMID:
28508225
42.

Reverse Genetics of Influenza B Viruses.

Nogales A, Perez DR, Santos J, Finch C, Martínez-Sobrido L.

Methods Mol Biol. 2017;1602:205-238. doi: 10.1007/978-1-4939-6964-7_14.

PMID:
28508223
43.

Lassa Virus Reverse Genetics.

Martínez-Sobrido L, Paessler S, de la Torre JC.

Methods Mol Biol. 2017;1602:185-204. doi: 10.1007/978-1-4939-6964-7_13.

PMID:
28508222
44.

Development of Recombinant Arenavirus-Based Vaccines.

Martínez-Sobrido L, de la Torre JC.

Methods Mol Biol. 2017;1581:133-149. doi: 10.1007/978-1-4939-6869-5_8.

PMID:
28374247
45.

Avian Interferons and Their Antiviral Effectors.

Santhakumar D, Rubbenstroth D, Martinez-Sobrido L, Munir M.

Front Immunol. 2017 Jan 31;8:49. doi: 10.3389/fimmu.2017.00049. eCollection 2017. Review.

46.

A live-attenuated influenza vaccine for H3N2 canine influenza virus.

Rodriguez L, Nogales A, Reilly EC, Topham DJ, Murcia PR, Parrish CR, Martinez Sobrido L.

Virology. 2017 Apr;504:96-106. doi: 10.1016/j.virol.2017.01.020. Epub 2017 Feb 3.

47.

Reverse Genetics Approaches for the Development of Influenza Vaccines.

Nogales A, Martínez-Sobrido L.

Int J Mol Sci. 2016 Dec 22;18(1). pii: E20. doi: 10.3390/ijms18010020. Review.

48.

NS1 Protein Amino Acid Changes D189N and V194I Affect Interferon Responses, Thermosensitivity, and Virulence of Circulating H3N2 Human Influenza A Viruses.

Nogales A, Martinez-Sobrido L, Topham DJ, DeDiego ML.

J Virol. 2017 Feb 14;91(5). pii: e01930-16. doi: 10.1128/JVI.01930-16. Print 2017 Mar 1.

49.

Temperature-Sensitive Live-Attenuated Canine Influenza Virus H3N8 Vaccine.

Nogales A, Rodriguez L, Chauché C, Huang K, Reilly EC, Topham DJ, Murcia PR, Parrish CR, Martínez-Sobrido L.

J Virol. 2017 Jan 31;91(4). pii: e02211-16. doi: 10.1128/JVI.02211-16. Print 2017 Feb 15.

50.

Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.

Cheng BYH, Nogales A, de la Torre JC, Martínez-Sobrido L.

Virology. 2017 Jan 15;501:35-46. doi: 10.1016/j.virol.2016.11.001. Epub 2016 Nov 14.

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