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Items: 1 to 50 of 51

1.

IC-Tagging methodology applied to the expression of viral glycoproteins and the difficult-to-express membrane-bound IGRP autoantigen.

Barreiro-Piñeiro N, Lostalé-Seijo I, Varela-Calviño R, Benavente J, Martínez-Costas JM.

Sci Rep. 2018 Nov 2;8(1):16286. doi: 10.1038/s41598-018-34488-3.

2.

Tuning the Size of Nanoassembles: A Hierarchical Transfer of Information from Dendrimers to Polyion Complexes.

Amaral SP, Tawara MH, Fernandez-Villamarin M, Borrajo E, Martínez-Costas J, Vidal A, Riguera R, Fernandez-Megia E.

Angew Chem Int Ed Engl. 2018 May 4;57(19):5273-5277. doi: 10.1002/anie.201712244. Epub 2018 Apr 6.

PMID:
29529349
3.

Selective G-quadruplex binding by oligoarginine-Ru(dppz) metallopeptides.

Bouzada D, Salvadó I, Barka G, Rama G, Martínez-Costas J, Lorca R, Somoza Á, Melle-Franco M, Vázquez ME, Vázquez López M.

Chem Commun (Camb). 2018 Jan 16;54(6):658-661. doi: 10.1039/c7cc08286j.

PMID:
29300399
4.

Microspheres-prime/rMVA-boost vaccination enhances humoral and cellular immune response in IFNAR(-/-) mice conferring protection against serotypes 1 and 4 of bluetongue virus.

Marín-López A, Calvo-Pinilla E, Barriales D, Lorenzo G, Benavente J, Brun A, Martínez-Costas JM, Ortego J.

Antiviral Res. 2017 Jun;142:55-62. doi: 10.1016/j.antiviral.2017.03.010. Epub 2017 Mar 18.

PMID:
28322923
5.

Membrane-disrupting iridium(iii) oligocationic organometallopeptides.

Salvadó I, Gamba I, Montenegro J, Martínez-Costas J, Brea JM, Loza MI, Vázquez López M, Vázquez ME.

Chem Commun (Camb). 2016 Sep 21;52(73):11008-11. doi: 10.1039/c6cc05537k. Epub 2016 Aug 19.

PMID:
27538788
6.

Response of Three Different Viruses to Interferon Priming and Dithiothreitol Treatment of Avian Cells.

Lostalé-Seijo I, Martínez-Costas J, Benavente J.

J Virol. 2016 Aug 26;90(18):8328-40. doi: 10.1128/JVI.01175-16. Print 2016 Sep 15.

7.

In Situ Functionalized Polymers for siRNA Delivery.

Priegue JM, Crisan DN, Martínez-Costas J, Granja JR, Fernandez-Trillo F, Montenegro J.

Angew Chem Int Ed Engl. 2016 Jun 20;55(26):7492-5. doi: 10.1002/anie.201601441. Epub 2016 Apr 21.

PMID:
27100572
8.

Real-time investigation of dynamic protein crystallization in living cells.

Schönherr R, Klinge M, Rudolph JM, Fita K, Rehders D, Lübber F, Schneegans S, Majoul IV, Duszenko M, Betzel C, Brandariz-Nuñez A, Martinez-Costas J, Duden R, Redecke L.

Struct Dyn. 2015 May 22;2(4):041712. doi: 10.1063/1.4921591. eCollection 2015 Jul.

9.

Interferon induction by avian reovirus.

Lostalé-Seijo I, Martínez-Costas J, Benavente J.

Virology. 2016 Jan;487:104-11. doi: 10.1016/j.virol.2015.10.009. Epub 2015 Oct 23.

10.

Using IC-Tagging Methodology for Production and Purification of Epitope-Loaded Protein Microspheres for Vaccination.

Barreiro-Piñeiro N, Menaya-Vargas R, Brandariz-Núñez A, Otero-Romero I, Lostalé-Seijo I, Benavente J, Martínez-Costas JM.

Methods Mol Biol. 2016;1349:25-34. doi: 10.1007/978-1-4939-3008-1_2.

PMID:
26458827
11.

MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria.

Sánchez MI, Martínez-Costas J, Mascareñas JL, Vázquez ME.

ACS Chem Biol. 2014 Dec 19;9(12):2742-7. doi: 10.1021/cb500552f. Epub 2014 Oct 21.

12.

Avian reovirus-triggered apoptosis enhances both virus spread and the processing of the viral nonstructural muNS protein.

Rodríguez-Grille J, Busch LK, Martínez-Costas J, Benavente J.

Virology. 2014 Aug;462-463:49-59. doi: 10.1016/j.virol.2014.04.039. Epub 2014 Jun 17.

13.

VP2, VP7, and NS1 proteins of bluetongue virus targeted in avian reovirus muNS-Mi microspheres elicit a protective immune response in IFNAR(-/-) mice.

Marín-López A, Otero-Romero I, de la Poza F, Menaya-Vargas R, Calvo-Pinilla E, Benavente J, Martínez-Costas JM, Ortego J.

Antiviral Res. 2014 Oct;110:42-51. doi: 10.1016/j.antiviral.2014.07.008. Epub 2014 Jul 22.

PMID:
25057758
14.

Programmed stereoselective assembly of DNA-binding helical metallopeptides.

Gamba I, Rama G, Ortega-Carrasco E, Maréchal JD, Martínez-Costas J, Vázquez ME, Vázquez López M.

Chem Commun (Camb). 2014 Oct 4;50(76):11097-100. doi: 10.1039/c4cc03606a.

PMID:
25014483
15.

Custom-fit ruthenium(II) metallopeptides: a new twist to DNA binding with coordination compounds.

Gamba I, Salvadó I, Rama G, Bertazzon M, Sánchez MI, Sánchez-Pedregal VM, Martínez-Costas J, Brissos RF, Gamez P, Mascareñas JL, Vázquez López M, Vázquez ME.

Chemistry. 2013 Sep 27;19(40):13369-75. doi: 10.1002/chem.201301629. Epub 2013 Aug 13.

PMID:
23943195
16.

Different intracellular distribution of avian reovirus core protein sigmaA in cells of avian and mammalian origin.

Vázquez-Iglesias L, Lostalé-Seijo I, Martínez-Costas J, Benavente J.

Virology. 2012 Oct 25;432(2):495-504. doi: 10.1016/j.virol.2012.07.007. Epub 2012 Jul 23.

17.

In vivo light-driven DNA binding and cellular uptake of nucleic acid stains.

Sánchez MI, Martínez-Costas J, Gonzalez F, Bermudez MA, Vázquez ME, Mascareñas JL.

ACS Chem Biol. 2012 Jul 20;7(7):1276-80. doi: 10.1021/cb300100r. Epub 2012 May 11.

PMID:
22550994
18.

IC-tagged proteins are able to interact with each other and perform complex reactions when integrated into muNS-derived inclusions.

Brandariz-Nuñez A, Otero-Romero I, Benavente J, Martinez-Costas JM.

J Biotechnol. 2011 Sep 20;155(3):284-6. doi: 10.1016/j.jbiotec.2011.07.010. Epub 2011 Jul 28.

PMID:
21802457
19.

Avian and mammalian reoviruses use different molecular mechanisms to synthesize their {micro}NS isoforms.

Busch LK, Rodríguez-Grille J, Casal JI, Martínez-Costas J, Benavente J.

J Gen Virol. 2011 Nov;92(Pt 11):2566-74. doi: 10.1099/vir.0.036459-0. Epub 2011 Jul 27.

PMID:
21795469
20.

A versatile molecular tagging method for targeting proteins to avian reovirus muNS inclusions. Use in protein immobilization and purification.

Brandariz-Nuñez A, Menaya-Vargas R, Benavente J, Martinez-Costas J.

PLoS One. 2010 Nov 12;5(11):e13961. doi: 10.1371/journal.pone.0013961.

21.

IC-tagging and protein relocation to ARV muNS inclusions: a method to study protein-protein interactions in the cytoplasm or nucleus of living cells.

Brandariz-Nuñez A, Menaya-Vargas R, Benavente J, Martinez-Costas J.

PLoS One. 2010 Nov 2;5(11):e13785. doi: 10.1371/journal.pone.0013785.

22.

Avian reovirus microNS protein forms homo-oligomeric inclusions in a microtubule-independent fashion, which involves specific regions of its C-terminal domain.

Brandariz-Nuñez A, Menaya-Vargas R, Benavente J, Martinez-Costas J.

J Virol. 2010 May;84(9):4289-301. doi: 10.1128/JVI.02534-09. Epub 2010 Feb 24.

23.

Bis-4-aminobenzamidines: versatile, fluorogenic A/T-selective dsDNA binders.

Vázquez O, Sánchez MI, Martínez-Costas J, Vázquez ME, Mascareñas JL.

Org Lett. 2010 Jan 15;12(2):216-9. doi: 10.1021/ol902501j.

PMID:
20000489
24.

Avian reovirus sigmaA localizes to the nucleolus and enters the nucleus by a nonclassical energy- and carrier-independent pathway.

Vázquez-Iglesias L, Lostalé-Seijo I, Martínez-Costas J, Benavente J.

J Virol. 2009 Oct;83(19):10163-75. doi: 10.1128/JVI.01080-09. Epub 2009 Jul 29.

25.

Efficient DNA binding and nuclear uptake by distamycin derivatives conjugated to octa-arginine sequences.

Vázquez O, Blanco-Canosa JB, Vázquez ME, Martínez-Costas J, Castedo L, Mascareñas JL.

Chembiochem. 2008 Nov 24;9(17):2822-9. doi: 10.1002/cbic.200800345.

PMID:
18942688
26.

Crystal structure of the avian reovirus inner capsid protein sigmaA.

Guardado-Calvo P, Vazquez-Iglesias L, Martinez-Costas J, Llamas-Saiz AL, Schoehn G, Fox GC, Hermo-Parrado XL, Benavente J, van Raaij MJ.

J Virol. 2008 Nov;82(22):11208-16. doi: 10.1128/JVI.00733-08. Epub 2008 Sep 17.

27.

Crystallization of the avian reovirus double-stranded RNA-binding and core protein sigmaA.

Hermo-Parrado XL, Guardado-Calvo P, Llamas-Saiz AL, Fox GC, Vazquez-Iglesias L, Martínez-Costas J, Benavente J, van Raaij MJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 May 1;63(Pt 5):426-9. Epub 2007 Apr 20.

28.

Avian reovirus: structure and biology.

Benavente J, Martínez-Costas J.

Virus Res. 2007 Feb;123(2):105-19. Epub 2006 Oct 2. Review.

PMID:
17018239
29.

Early steps in avian reovirus morphogenesis.

Benavente J, Martínez-Costas J.

Curr Top Microbiol Immunol. 2006;309:67-85. Review.

PMID:
16909897
30.

Crystallization of the C-terminal globular domain of avian reovirus fibre.

van Raaij MJ, Hermo Parrado XL, Guardado Calvo P, Fox GC, Llamas-Saiz AL, Costas C, Martínez-Costas J, Benavente J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jul 1;61(Pt 7):651-4. Epub 2005 Jun 15.

31.

Structure of the carboxy-terminal receptor-binding domain of avian reovirus fibre sigmaC.

Guardado Calvo P, Fox GC, Hermo Parrado XL, Llamas-Saiz AL, Costas C, Martínez-Costas J, Benavente J, van Raaij MJ.

J Mol Biol. 2005 Nov 18;354(1):137-49. Epub 2005 Sep 30.

PMID:
16236316
32.

High affinity, sequence specific DNA binding by synthetic tripyrrole-peptide conjugates.

Blanco JB, Vázquez O, Martínez-Costas J, Castedo L, Mascareñas JL.

Chemistry. 2005 Jul 4;11(14):4171-8.

PMID:
15861479
33.

Characterization of the nucleic acid-binding activity of the avian reovirus non-structural protein sigma NS.

Tourís-Otero F, Martínez-Costas J, Vakharia VN, Benavente J.

J Gen Virol. 2005 Apr;86(Pt 4):1159-69.

PMID:
15784910
34.
35.

Avian reovirus morphogenesis occurs within viral factories and begins with the selective recruitment of sigmaNS and lambdaA to microNS inclusions.

Tourís-Otero F, Cortez-San Martín M, Martínez-Costas J, Benavente J.

J Mol Biol. 2004 Aug 6;341(2):361-74.

PMID:
15276829
36.

Avian reovirus nonstructural protein microNS forms viroplasm-like inclusions and recruits protein sigmaNS to these structures.

Touris-Otero F, Martínez-Costas J, Vakharia VN, Benavente J.

Virology. 2004 Feb 5;319(1):94-106.

37.

A synthetic miniprotein that binds specific DNA sequences by contacting both the major and the minor groove.

Blanco JB, Vázquez ME, Martinez-Costas J, Castedo L, Mascareñas JL.

Chem Biol. 2003 Aug;10(8):713-22.

PMID:
12954330
38.

Evidence that avian reovirus sigmaA protein is an inhibitor of the double-stranded RNA-dependent protein kinase.

González-López C, Martínez-Costas J, Esteban M, Benavente J.

J Gen Virol. 2003 Jun;84(Pt 6):1629-39.

PMID:
12771434
40.

Cloning, expression, and characterization of avian reovirus guanylyltransferase.

Hsiao J, Martínez-Costas J, Benavente J, Vakharia VN.

Virology. 2002 May 10;296(2):288-99.

41.

Modification of late membrane permeability in avian reovirus-infected cells: viroporin activity of the S1-encoded nonstructural p10 protein.

Bodelón G, Labrada L, Martínez-Costas J, Benavente J.

J Biol Chem. 2002 May 17;277(20):17789-96. Epub 2002 Mar 13.

42.
44.

Possible involvement of the double-stranded RNA-binding core protein sigmaA in the resistance of avian reovirus to interferon.

Martínez-Costas J, González-López C, Vakharia VN, Benavente J.

J Virol. 2000 Feb;74(3):1124-31.

45.

Guanylyltransferase and RNA 5'-triphosphatase activities of the purified expressed VP4 protein of bluetongue virus.

Martinez-Costas J, Sutton G, Ramadevi N, Roy P.

J Mol Biol. 1998 Jul 31;280(5):859-66.

PMID:
9671555
47.

Protein architecture of avian reovirus S1133 and identification of the cell attachment protein.

Martínez-Costas J, Grande A, Varela R, García-Martínez C, Benavente J.

J Virol. 1997 Jan;71(1):59-64.

48.

Intracellular posttranslational modifications of S1133 avian reovirus proteins.

Varela R, Martínez-Costas J, Mallo M, Benavente J.

J Virol. 1996 May;70(5):2974-81.

49.

Endogenous enzymatic activities of the avian reovirus S1133: identification of the viral capping enzyme.

Martinez-Costas J, Varela R, Benavente J.

Virology. 1995 Feb 1;206(2):1017-26.

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