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Items: 1 to 50 of 302

1.

Patient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs.

Holmes EAF, Plumpton C, Baker GA, Jacoby A, Ring A, Williamson P, Marson A, Hughes DA.

Clin Pharmacol Ther. 2018 Sep 11. doi: 10.1002/cpt.1231. [Epub ahead of print]

PMID:
30204252
2.

A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of action.

Wong SQ, Jones A, Dodd S, Grimes D, Barclay JW, Marson AG, Cunliffe VT, Burgoyne RD, Sills GJ, Morgan A.

J Neurosci Methods. 2018 Sep 3;309:132-142. doi: 10.1016/j.jneumeth.2018.09.004. [Epub ahead of print]

3.

Nerve root block versus surgery (NERVES) for the treatment of radicular pain secondary to a prolapsed intervertebral disc herniation: study protocol for a multi-centre randomised controlled trial.

Wilby MJ, Hopkins C, Bedson E, Howlin S, Burnside G, Conroy EJ, Hughes DA, Sharma M, Marson A, Clark SR, Williamson P.

Trials. 2018 Sep 5;19(1):475. doi: 10.1186/s13063-018-2677-5.

4.

CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.

Chen SH, Jang GM, Hüttenhain R, Gordon DE, Du D, Newton BW, Johnson JR, Hiatt J, Hultquist JF, Johnson TL, Liu YL, Burton LA, Ye J, Reichermeier KM, Stroud RM, Marson A, Debnath J, Gross JD, Krogan NJ.

EMBO J. 2018 Sep 14;37(18). pii: e97508. doi: 10.15252/embj.201797508. Epub 2018 Aug 30.

PMID:
30166453
5.

Sodium valproate versus phenytoin monotherapy for epilepsy: an individual participant data review.

Nevitt SJ, Marson AG, Weston J, Tudur Smith C.

Cochrane Database Syst Rev. 2018 Aug 9;8:CD001769. doi: 10.1002/14651858.CD001769.pub4. [Epub ahead of print] Review.

PMID:
30091458
6.

Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study.

May P, Girard S, Harrer M, Bobbili DR, Schubert J, Wolking S, Becker F, Lachance-Touchette P, Meloche C, Gravel M, Niturad CE, Knaus J, De Kovel C, Toliat M, Polvi A, Iacomino M, Guerrero-López R, Baulac S, Marini C, Thiele H, Altmüller J, Jabbari K, Ruppert AK, Jurkowski W, Lal D, Rusconi R, Cestèle S, Terragni B, Coombs ID, Reid CA, Striano P, Caglayan H, Siren A, Everett K, Møller RS, Hjalgrim H, Muhle H, Helbig I, Kunz WS, Weber YG, Weckhuysen S, Jonghe P, Sisodiya SM, Nabbout R, Franceschetti S, Coppola A, Vari MS, Kasteleijn-Nolst Trenité D, Baykan B, Ozbek U, Bebek N, Klein KM, Rosenow F, Nguyen DK, Dubeau F, Carmant L, Lortie A, Desbiens R, Clément JF, Cieuta-Walti C, Sills GJ, Auce P, Francis B, Johnson MR, Marson AG, Berghuis B, Sander JW, Avbersek A, McCormack M, Cavalleri GL, Delanty N, Depondt C, Krenn M, Zimprich F, Peter S, Nikanorova M, Kraaij R, van Rooij J, Balling R, Ikram MA, Uitterlinden AG, Avanzini G, Schorge S, Petrou S, Mantegazza M, Sander T, LeGuern E, Serratosa JM, Koeleman BPC, Palotie A, Lehesjoki AE, Nothnagel M, Nürnberg P, Maljevic S, Zara F, Cossette P, Krause R, Lerche H; Epicure Consortium; EuroEPINOMICS CoGIE Consortium; EpiPGX Consortium.

Lancet Neurol. 2018 Aug;17(8):699-708. doi: 10.1016/S1474-4422(18)30215-1. Epub 2018 Jul 17.

PMID:
30033060
7.

Reprogramming human T cell function and specificity with non-viral genome targeting.

Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel JN, Pellerin L, Carmody D, Alkorta-Aranburu G, Del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A.

Nature. 2018 Jul;559(7714):405-409. doi: 10.1038/s41586-018-0326-5. Epub 2018 Jul 11.

PMID:
29995861
8.

Revisiting IL-2: Biology and therapeutic prospects.

Abbas AK, Trotta E, R Simeonov D, Marson A, Bluestone JA.

Sci Immunol. 2018 Jul 6;3(25). pii: eaat1482. doi: 10.1126/sciimmunol.aat1482. Review.

PMID:
29980618
9.

Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.

Nevitt SJ, Tudur Smith C, Weston J, Marson AG.

Cochrane Database Syst Rev. 2018 Jun 28;6:CD001031. doi: 10.1002/14651858.CD001031.pub4. Review.

PMID:
29952431
10.

Analysis of shared heritability in common disorders of the brain.

Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Rogé B, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Jamain S, Maaser A, Fischer SB, Reinbold CS, Fullerton JM, Guzman-Parra J, Mayoral F, Schofield PR, Cichon S, Mühleisen TW, Degenhardt F, Schumacher J, Bauer M, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Rouleau GA, Turecki G, Ophoff R, Pato C, Anjorin A, Stahl E, Leber M, Czerski PM, Cruceanu C, Jones IR, Posthuma D, Andlauer TFM, Forstner AJ, Streit F, Baune BT, Air T, Sinnamon G, Wray NR, MacIntyre DJ, Porteous D, Homuth G, Rivera M, Grove J, Middeldorp CM, Hickie I, Pergadia M, Mehta D, Smit JH, Jansen R, de Geus E, Dunn E, Li QS, Nauck M, Schoevers RA, Beekman AT, Knowles JA, Viktorin A, Arnold P, Barr CL, Bedoya-Berrio G, Bienvenu OJ, Brentani H, Burton C, Camarena B, Cappi C, Cath D, Cavallini M, Cusi D, Darrow S, Denys D, Derks EM, Dietrich A, Fernandez T, Figee M, Freimer N, Gerber G, Grados M, Greenberg E, Hanna GL, Hartmann A, Hirschtritt ME, Hoekstra PJ, Huang A, Huyser C, Illmann C, Jenike M, Kuperman S, Leventhal B, Lochner C, Lyon GJ, Macciardi F, Madruga-Garrido M, Malaty IA, Maras A, McGrath L, Miguel EC, Mir P, Nestadt G, Nicolini H, Okun MS, Pakstis A, Paschou P, Piacentini J, Pittenger C, Plessen K, Ramensky V, Ramos EM, Reus V, Richter MA, Riddle MA, Robertson MM, Roessner V, Rosário M, Samuels JF, Sandor P, Stein DJ, Tsetsos F, Van Nieuwerburgh F, Weatherall S, Wendland JR, Wolanczyk T, Worbe Y, Zai G, Goes FS, McLaughlin N, Nestadt PS, Grabe HJ, Depienne C, Konkashbaev A, Lanzagorta N, Valencia-Duarte A, Bramon E, Buccola N, Cahn W, Cairns M, Chong SA, Cohen D, Crespo-Facorro B, Crowley J, Davidson M, DeLisi L, Dinan T, Donohoe G, Drapeau E, Duan J, Haan L, Hougaard D, Karachanak-Yankova S, Khrunin A, Klovins J, Kučinskas V, Lee Chee Keong J, Limborska S, Loughland C, Lönnqvist J, Maher B, Mattheisen M, McDonald C, Murphy KC, Nenadic I, van Os J, Pantelis C, Pato M, Petryshen T, Quested D, Roussos P, Sanders AR, Schall U, Schwab SG, Sim K, So HC, Stögmann E, Subramaniam M, Toncheva D, Waddington J, Walters J, Weiser M, Cheng W, Cloninger R, Curtis D, Gejman PV, Henskens F, Mattingsdal M, Oh SY, Scott R, Webb B, Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM, Schott JM, Anney R, Elia J, Grigoroiu-Serbanescu M, Edenberg HJ, Murray R.

Science. 2018 Jun 22;360(6395). pii: eaap8757. doi: 10.1126/science.aap8757.

11.

Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2018 Jul;559(7715):E13. doi: 10.1038/s41586-018-0227-7.

PMID:
29899441
12.

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms.

Farboud B, Jarvis E, Roth TL, Shin J, Corn JE, Marson A, Meyer BJ, Patel NH, Hochstrasser ML.

J Vis Exp. 2018 May 25;(135). doi: 10.3791/57350.

13.

Antiepileptic drugs as prophylaxis for postcraniotomy seizures.

Greenhalgh J, Weston J, Dundar Y, Nevitt SJ, Marson AG.

Cochrane Database Syst Rev. 2018 May 23;5:CD007286. doi: 10.1002/14651858.CD007286.pub4. Review.

PMID:
29791030
14.

Rufinamide add-on therapy for refractory epilepsy.

Panebianco M, Prabhakar H, Marson AG.

Cochrane Database Syst Rev. 2018 Apr 25;4:CD011772. doi: 10.1002/14651858.CD011772.pub2. Review.

PMID:
29691835
15.

The Modified Ketogenic Diet in Adults with Glioblastoma: An Evaluation of Feasibility and Deliverability within the National Health Service.

Martin-McGill KJ, Marson AG, Tudur Smith C, Jenkinson MD.

Nutr Cancer. 2018 May-Jun;70(4):643-649. doi: 10.1080/01635581.2018.1460677. Epub 2018 Apr 18.

PMID:
29668317
16.

The role of ketogenic diets in the therapeutic management of adult and paediatric gliomas: a systematic review.

Martin-McGill KJ, Srikandarajah N, Marson AG, Tudur Smith C, Jenkinson MD.

CNS Oncol. 2018 Apr;7(2):CNS17. doi: 10.2217/cns-2017-0030. Epub 2018 Apr 16.

17.

Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins.

Wu CM, Roth TL, Baglaenko Y, Ferri DM, Brauer P, Zuniga-Pflucker JC, Rosbe KW, Wither JE, Marson A, Allen CDC.

J Immunol Methods. 2018 Jun;457:33-40. doi: 10.1016/j.jim.2018.03.009. Epub 2018 Mar 31.

PMID:
29614266
18.

A voxel-based asymmetry study of the relationship between hemispheric asymmetry and language dominance in Wada tested patients.

Keller SS, Roberts N, Baker G, Sluming V, Cezayirli E, Mayes A, Eldridge P, Marson AG, Wieshmann UC.

Hum Brain Mapp. 2018 Jul;39(7):3032-3045. doi: 10.1002/hbm.24058. Epub 2018 Mar 23.

19.

The prescribable drugs with efficacy in experimental epilepsies (PDE3) database for drug repurposing research in epilepsy.

Sivapalarajah S, Krishnakumar M, Bickerstaffe H, Chan Y, Clarkson J, Hampden-Martin A, Mirza A, Tanti M, Marson A, Pirmohamed M, Mirza N.

Epilepsia. 2018 Feb;59(2):492-501. doi: 10.1111/epi.13994. Epub 2018 Jan 17.

PMID:
29341109
20.

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.

McCormack M, Gui H, Ingason A, Speed D, Wright GEB, Zhang EJ, Secolin R, Yasuda C, Kwok M, Wolking S, Becker F, Rau S, Avbersek A, Heggeli K, Leu C, Depondt C, Sills GJ, Marson AG, Auce P, Brodie MJ, Francis B, Johnson MR, Koeleman BPC, Striano P, Coppola A, Zara F, Kunz WS, Sander JW, Lerche H, Klein KM, Weckhuysen S, Krenn M, Gudmundsson LJ, Stefánsson K, Krause R, Shear N, Ross CJD, Delanty N; EPIGEN Consortium;, Pirmohamed M, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety;, Cendes F, Lopes-Cendes I, Liao WP, O'Brien TJ, Sisodiya SM; EpiPGX Consortium;, Cherny S, Kwan P, Baum L; International League Against Epilepsy Consortium on Complex Epilepsies;, Cavalleri GL.

Neurology. 2018 Jan 23;90(4):e332-e341. doi: 10.1212/WNL.0000000000004853. Epub 2017 Dec 29.

21.

Epilepsy and psychosis: a practical approach.

Maguire M, Singh J, Marson A.

Pract Neurol. 2018 Apr;18(2):106-114. doi: 10.1136/practneurol-2017-001775. Epub 2017 Dec 22. Review.

PMID:
29273616
22.

A critical review of recent clinical practice guidelines on management of cryptorchidism.

Kim JK, Chua ME, Ming JM, Santos JD, Zani-Ruttenstock E, Marson A, Bayley M, Koyle MA.

J Pediatr Surg. 2018 Oct;53(10):2041-2047. doi: 10.1016/j.jpedsurg.2017.11.050. Epub 2017 Nov 24. Review.

PMID:
29269095
23.

Breakthrough seizures-Further analysis of the Standard versus New Antiepileptic Drugs (SANAD) study.

Bonnett LJ, Powell GA, Tudur Smith C, Marson AG.

PLoS One. 2017 Dec 21;12(12):e0190035. doi: 10.1371/journal.pone.0190035. eCollection 2017.

24.

Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.

Nevitt SJ, Sudell M, Weston J, Tudur Smith C, Marson AG.

Cochrane Database Syst Rev. 2017 Dec 15;12:CD011412. doi: 10.1002/14651858.CD011412.pub3. Review.

PMID:
29243813
25.

Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.

Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, Ye CJ.

Nat Biotechnol. 2018 Jan;36(1):89-94. doi: 10.1038/nbt.4042. Epub 2017 Dec 11.

26.

Ketogenic diets as an adjuvant therapy in glioblastoma (the KEATING trial): study protocol for a randomised pilot study.

Martin-McGill KJ, Marson AG, Tudur Smith C, Jenkinson MD.

Pilot Feasibility Stud. 2017 Nov 28;3:67. doi: 10.1186/s40814-017-0209-9. eCollection 2017.

27.

Preoperative progressive pneumoperitoneum in obese patients with loss of domain hernias.

Valezi AC, de Melo BGF, Marson AC, Liberatti M, Lopes AG Jr.

Surg Obes Relat Dis. 2018 Feb;14(2):138-142. doi: 10.1016/j.soard.2017.10.009. Epub 2017 Oct 16.

PMID:
29174884
28.

Model-based sensitivity analysis for outcome reporting bias in the meta analysis of benefit and harm outcomes.

Copas J, Marson A, Williamson P, Kirkham J.

Stat Methods Med Res. 2017 Jan 1:962280217738546. doi: 10.1177/0962280217738546. [Epub ahead of print]

PMID:
29134855
29.

Maternal Use of Antiepileptic Agents During Pregnancy and Major Congenital Malformations in Children.

Bromley RL, Weston J, Marson AG.

JAMA. 2017 Nov 7;318(17):1700-1701. doi: 10.1001/jama.2017.14485.

PMID:
29114815
30.

Effects of efforts to optimise morbidity and mortality rounds to serve contemporary quality improvement and educational goals: a systematic review.

Smaggus A, Mrkobrada M, Marson A, Appleton A.

BMJ Qual Saf. 2018 Jan;27(1):74-84. doi: 10.1136/bmjqs-2017-006632. Epub 2017 Sep 29. Review.

PMID:
28971889
31.

Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.

Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, Simeonov DR, Suliman N, Li R, Xu J, Flynn RA, Kundaje A, Khavari PA, Marson A, Corn JE, Quertermous T, Greenleaf WJ, Chang HY.

Nat Genet. 2017 Nov;49(11):1602-1612. doi: 10.1038/ng.3963. Epub 2017 Sep 25.

32.

The modified ketogenic diet for adults with refractory epilepsy: An evaluation of a set up service.

Martin-McGill KJ, Jenkinson MD, Tudur Smith C, Marson AG.

Seizure. 2017 Nov;52:1-6. doi: 10.1016/j.seizure.2017.08.013. Epub 2017 Sep 1.

PMID:
28915401
33.

"T-bet"-ing on autoimmunity variants.

Nguyen MLT, Simeonov DR, Marson A.

PLoS Genet. 2017 Sep 7;13(9):e1006924. doi: 10.1371/journal.pgen.1006924. eCollection 2017 Sep. No abstract available.

34.

Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.

Androsova G, Krause R, Borghei M, Wassenaar M, Auce P, Avbersek A, Becker F, Berghuis B, Campbell E, Coppola A, Francis B, Wolking S, Cavalleri GL, Craig J, Delanty N, Koeleman BPC, Kunz WS, Lerche H, Marson AG, Sander JW, Sills GJ, Striano P, Zara F, Sisodiya SM, Depondt C; EpiPGX Consortium.

Epilepsia. 2017 Oct;58(10):1734-1741. doi: 10.1111/epi.13871. Epub 2017 Aug 31.

PMID:
28857179
35.

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A.

Nature. 2017 Sep 7;549(7670):111-115. doi: 10.1038/nature23875. Epub 2017 Aug 30. Erratum in: Nature. 2018 Jul;559(7715):E13.

36.

Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access.

Powell GA, Bonnett LJ, Tudur-Smith C, Hughes DA, Williamson PR, Marson AG.

Trials. 2017 Aug 23;18(1):389. doi: 10.1186/s13063-017-2135-9. Review.

37.

Deep brain and cortical stimulation for epilepsy.

Sprengers M, Vonck K, Carrette E, Marson AG, Boon P.

Cochrane Database Syst Rev. 2017 Jul 18;7:CD008497. doi: 10.1002/14651858.CD008497.pub3. Review.

PMID:
28718878
38.

Resource implications of preparing individual participant data from a clinical trial to share with external researchers.

Tudur Smith C, Nevitt S, Appelbe D, Appleton R, Dixon P, Harrison J, Marson A, Williamson P, Tremain E.

Trials. 2017 Jul 17;18(1):319. doi: 10.1186/s13063-017-2067-4.

39.
40.

Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.

Nevitt SJ, Sudell M, Weston J, Tudur Smith C, Marson AG.

Cochrane Database Syst Rev. 2017 Jun 29;6:CD011412. doi: 10.1002/14651858.CD011412.pub2. Review. Update in: Cochrane Database Syst Rev. 2017 Dec 15;12 :CD011412.

PMID:
28661008
41.

Epilepsy and Pregnancy: For healthy pregnancies and happy outcomes. Suggestions for service improvements from the Multispecialty UK Epilepsy Mortality Group.

Leach JP, Smith PE, Craig J, Bagary M, Cavanagh D, Duncan S, Kelso ARC, Marson AG, McCorry D, Nashef L, Nelson-Piercy C, Northridge R, Sieradzan K, Thangaratinam S, Walker M, Winterbottom J, Reuber M.

Seizure. 2017 Aug;50:67-72. doi: 10.1016/j.seizure.2017.05.004. Epub 2017 Jun 1. Review.

42.

Epilepsy management in older people: Lessons from National Audit of Seizure management in Hospitals (NASH).

Ziso B, Dixon PA, Marson AG.

Seizure. 2017 Aug;50:33-37. doi: 10.1016/j.seizure.2017.05.002. Epub 2017 May 30.

43.

Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from Epoxide Metabolites of Carbamazepine in Patients.

Yip VLM, Meng X, Maggs JL, Jenkins RE, Marlot PT, Marson AG, Park BK, Pirmohamed M.

Chem Res Toxicol. 2017 Jul 17;30(7):1419-1435. doi: 10.1021/acs.chemrestox.7b00063. Epub 2017 Jun 12.

PMID:
28562019
44.

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy.

Walker LE, Frigerio F, Ravizza T, Ricci E, Tse K, Jenkins RE, Sills GJ, Jorgensen A, Porcu L, Thippeswamy T, Alapirtti T, Peltola J, Brodie MJ, Park BK, Marson AG, Antoine DJ, Vezzani A, Pirmohamed M.

J Clin Invest. 2017 Jun 1;127(6):2118-2132. doi: 10.1172/JCI92001. Epub 2017 May 15.

45.

Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis.

Lamberink HJ, Otte WM, Geerts AT, Pavlovic M, Ramos-Lizana J, Marson AG, Overweg J, Sauma L, Specchio LM, Tennison M, Cardoso TMO, Shinnar S, Schmidt D, Geleijns K, Braun KPJ.

Lancet Neurol. 2017 Jul;16(7):523-531. doi: 10.1016/S1474-4422(17)30114-X. Epub 2017 May 5. Review. Erratum in: Lancet Neurol. 2017 Aug;16(8):584.

PMID:
28483337
46.

Comparing Generic and Condition-Specific Preference-Based Measures in Epilepsy: EQ-5D-3L and NEWQOL-6D.

Mulhern B, Pink J, Rowen D, Borghs S, Butt T, Hughes D, Marson A, Brazier J.

Value Health. 2017 Apr;20(4):687-693. doi: 10.1016/j.jval.2016.03.1860. Epub 2016 May 25.

47.

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.

Rupp LJ, Schumann K, Roybal KT, Gate RE, Ye CJ, Lim WA, Marson A.

Sci Rep. 2017 Apr 7;7(1):737. doi: 10.1038/s41598-017-00462-8.

48.

Exploring changes over time and characteristics associated with data retrieval across individual participant data meta-analyses: systematic review.

Nevitt SJ, Marson AG, Davie B, Reynolds S, Williams L, Smith CT.

BMJ. 2017 Apr 5;357:j1390. doi: 10.1136/bmj.j1390. Review.

49.

Genetic regulation of gene expression in the epileptic human hippocampus.

Mirza N, Appleton R, Burn S, du Plessis D, Duncan R, Farah JO, Feenstra B, Hviid A, Josan V, Mohanraj R, Shukralla A, Sills GJ, Marson AG, Pirmohamed M.

Hum Mol Genet. 2017 May 1;26(9):1759-1769. doi: 10.1093/hmg/ddx061.

50.

A disease, disorder, illness or condition: How to label epilepsy?

Noble AJ, Robinson A, Marson AG.

Acta Neurol Scand. 2017 Nov;136(5):536-540. doi: 10.1111/ane.12757. Epub 2017 Mar 14.

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