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Items: 45


High FA2H and UGT8 transcript levels predict hydroxylated hexosylceramide accumulation in lung adenocarcinoma.

Lemay AM, Courtemanche O, Couttas TA, Jamsari G, Gagné A, Bossé Y, Joubert P, Don AS, Marsolais D.

J Lipid Res. 2019 Oct;60(10):1776-1786. doi: 10.1194/jlr.M093955. Epub 2019 Aug 13.


Metabolic adaptation of airway smooth muscle cells to a SPHK2 substrate precedes cytostasis.

Blais-Lecours P, Laouafa S, Arias-Reyes C, Santos WL, Joseph V, Burgess JK, Halayko AJ, Soliz J, Marsolais D.

Am J Respir Cell Mol Biol. 2019 Jun 27. doi: 10.1165/rcmb.2018-0397OC. [Epub ahead of print]


CD200 in asthma.

Lauzon-Joset JF, Marsolais D, Tardif-Pellerin É, Patoine D, Bissonnette EY.

Int J Biochem Cell Biol. 2019 Jul;112:141-144. doi: 10.1016/j.biocel.2019.05.003. Epub 2019 May 8.


Impairment of chemical hypoxia-induced sphingosine kinase-1 expression and activation in rheumatoid arthritis synovial fibroblasts: A signature of exhaustion?

Zhao C, Amiable N, Laflamme M, Marsolais D, Di Battista JA, Fernandes MJ, Bourgoin SG.

Biochem Pharmacol. 2019 Jul;165:249-262. doi: 10.1016/j.bcp.2019.02.009. Epub 2019 Feb 10.


Lipopolysaccharide impacts murine CD103+ DC differentiation, altering the lung DC population balance.

Brassard J, Maheux C, Langlois A, Bernatchez E, Marsolais D, Flamand N, Blanchet MR.

Eur J Immunol. 2019 Apr;49(4):638-652. doi: 10.1002/eji.201847910. Epub 2019 Feb 12.


Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography.

Mailhot-Larouche S, Deschênes L, Lortie K, Gazzola M, Marsolais D, Brunet D, Robichaud A, Bossé Y.

J Vis Exp. 2018 Jul 10;(137). doi: 10.3791/57778.


Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice.

Talbot M, Hamel-Auger M, Beaulieu MJ, Gazzola M, Lechasseur A, Aubin S, Paré MÈ, Marsolais D, Bossé Y, Morissette MC.

Respir Res. 2018 Jul 3;19(1):131. doi: 10.1186/s12931-018-0833-9.


Organic components of airborne dust influence the magnitude and kinetics of dendritic cell activation.

Boucher M, Blais Lecours P, Létourneau V, Veillette M, Duchaine C, Marsolais D.

Toxicol In Vitro. 2018 Aug;50:391-398. doi: 10.1016/j.tiv.2018.04.011. Epub 2018 Apr 27.


Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure.

Carter S, Miard S, Caron A, Sallé-Lefort S, St-Pierre P, Anhê FF, Lavoie-Charland E, Blais-Lecours P, Drolet MC, Lefebvre JS, Lacombe J, Deshaies Y, Couet J, Laplante M, Ferron M, Bossé Y, Marette A, Richard D, Marsolais D, Picard F.

Diabetes. 2018 Jul;67(7):1285-1296. doi: 10.2337/db17-0558. Epub 2018 Mar 1.


CD34 Differentially Regulates Contractile and Noncontractile Elements of Airway Reactivity.

Lortie K, Maheux C, Gendron D, Langlois A, Beaulieu MJ, Marsolais D, Bossé Y, Blanchet MR.

Am J Respir Cell Mol Biol. 2018 Jan;58(1):79-88. doi: 10.1165/rcmb.2017-0008OC.


Hypersensitivity pneumonitis onset and severity is regulated by CD103 dendritic cell expression.

Bernatchez E, Langlois A, Brassard J, Flamand N, Marsolais D, Blanchet MR.

PLoS One. 2017 Jun 19;12(6):e0179678. doi: 10.1371/journal.pone.0179678. eCollection 2017.


An in vitro study examining the duration between deep inspirations on the rate of renarrowing.

Mailhot-Larouche S, Lortie K, Marsolais D, Flamand N, Bossé Y.

Respir Physiol Neurobiol. 2017 Sep;243:13-19. doi: 10.1016/j.resp.2017.04.013. Epub 2017 May 6.


A sphingosine-1-phosphate receptor 1 agonist inhibits tertiary lymphoid tissue reactivation and hypersensitivity in the lung.

Huppé CA, Blais Lecours P, Lechasseur A, Gendron DR, Lemay AM, Bissonnette EY, Blanchet MR, Duchaine C, Morissette MC, Rosen H, Marsolais D.

Mucosal Immunol. 2018 Jan;11(1):112-119. doi: 10.1038/mi.2017.37. Epub 2017 Apr 19.


Methanosphaera stadtmanae induces a type IV hypersensitivity response in a mouse model of airway inflammation.

Bernatchez E, Gold MJ, Langlois A, Blais-Lecours P, Boucher M, Duchaine C, Marsolais D, McNagny KM, Blanchet MR.

Physiol Rep. 2017 Apr;5(7). pii: e13163. doi: 10.14814/phy2.13163.


FTY720 promotes pulmonary fibrosis when administered during the remodelling phase following a bleomycin-induced lung injury.

Gendron DR, Lemay AM, Lecours PB, Perreault-Vallières V, Huppé CA, Bossé Y, Blanchet MR, Dion G, Marsolais D.

Pulm Pharmacol Ther. 2017 Jun;44:50-56. doi: 10.1016/j.pupt.2017.03.010. Epub 2017 Mar 16.


A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma.

Gendron DR, Lecours PB, Lemay AM, Beaulieu MJ, Huppé CA, Lee-Gosselin A, Flamand N, Don AS, Bissonnette É, Blanchet MR, Laplante M, Bourgoin SG, Bossé Y, Marsolais D.

Front Pharmacol. 2017 Feb 21;8:78. doi: 10.3389/fphar.2017.00078. eCollection 2017.


The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors.

Turcotte C, Zarini S, Jean S, Martin C, Murphy RC, Marsolais D, Laviolette M, Blanchet MR, Flamand N.

J Immunol. 2017 Apr 15;198(8):3255-3263. doi: 10.4049/jimmunol.1601767. Epub 2017 Mar 3.


Amplification of Adipogenic Commitment by VSTM2A.

Secco B, Camiré É, Brière MA, Caron A, Billong A, Gélinas Y, Lemay AM, Tharp KM, Lee PL, Gobeil S, Guimond JV, Patey N, Guertin DA, Stahl A, Haddad É, Marsolais D, Bossé Y, Birsoy K, Laplante M.

Cell Rep. 2017 Jan 3;18(1):93-106. doi: 10.1016/j.celrep.2016.12.015.


Smooth muscle in human bronchi is disposed to resist airway distension.

Gazzola M, Henry C, Couture C, Marsolais D, King GG, Fredberg JJ, Bossé Y.

Respir Physiol Neurobiol. 2016 Jul 15;229:51-8. doi: 10.1016/j.resp.2016.04.005. Epub 2016 Apr 16.


Pulmonary CD103 expression regulates airway inflammation in asthma.

Bernatchez E, Gold MJ, Langlois A, Lemay AM, Brassard J, Flamand N, Marsolais D, McNagny KM, Blanchet MR.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15;308(8):L816-26. doi: 10.1152/ajplung.00319.2014. Epub 2015 Feb 13.


Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma.

Gendron D, Lemay AM, Tremblay C, Lai LJ, Langlois A, Bernatchez É, Flamand N, Blanchet MR, Don AS, Bossé Y, Bissonnette É, Marsolais D.

Respir Res. 2015 Feb 3;16:7. doi: 10.1186/s12931-015-0180-z.


The gain of smooth muscle's contractile capacity induced by tone on in vivo airway responsiveness in mice.

Lee-Gosselin A, Gendron D, Blanchet MR, Marsolais D, Bossé Y.

J Appl Physiol (1985). 2015 Mar 15;118(6):692-8. doi: 10.1152/japplphysiol.00645.2014. Epub 2015 Jan 8.


Lung CD200 Receptor Activation Abrogates Airway Hyperresponsiveness in Experimental Asthma.

Lauzon-Joset JF, Langlois A, Lai LJ, Santerre K, Lee-Gosselin A, Bossé Y, Marsolais D, Bissonnette EY.

Am J Respir Cell Mol Biol. 2015 Aug;53(2):276-84. doi: 10.1165/rcmb.2014-0229OC.


Mouse models of allergic asthma.

Gold M, Marsolais D, Blanchet MR.

Methods Mol Biol. 2015;1220:503-19. doi: 10.1007/978-1-4939-1568-2_31.


Increased prevalence of Methanosphaera stadtmanae in inflammatory bowel diseases.

Blais Lecours P, Marsolais D, Cormier Y, Berberi M, Haché C, Bourdages R, Duchaine C.

PLoS One. 2014 Feb 3;9(2):e87734. doi: 10.1371/journal.pone.0087734. eCollection 2014.


Monocyte depletion increases local proliferation of macrophage subsets after skeletal muscle injury.

Côté CH, Bouchard P, van Rooijen N, Marsolais D, Duchesne E.

BMC Musculoskelet Disord. 2013 Dec 19;14:359. doi: 10.1186/1471-2474-14-359.


Dysregulation of alveolar macrophages unleashes dendritic cell-mediated mechanisms of allergic airway inflammation.

Lauzon-Joset JF, Marsolais D, Langlois A, Bissonnette EY.

Mucosal Immunol. 2014 Jan;7(1):155-64. doi: 10.1038/mi.2013.34. Epub 2013 May 29.


Three phases of CD8 T cell response in the lung following H1N1 influenza infection and sphingosine 1 phosphate agonist therapy.

Matheu MP, Teijaro JR, Walsh KB, Greenberg ML, Marsolais D, Parker I, Rosen H, Oldstone MB, Cahalan MD.

PLoS One. 2013;8(3):e58033. doi: 10.1371/journal.pone.0058033. Epub 2013 Mar 22.


Characterization of bioaerosols from dairy barns: reconstructing the puzzle of occupational respiratory diseases by using molecular approaches.

Blais Lecours P, Veillette M, Marsolais D, Duchaine C.

Appl Environ Microbiol. 2012 May;78(9):3242-8. doi: 10.1128/AEM.07661-11. Epub 2012 Feb 24.


Immunogenic properties of archaeal species found in bioaerosols.

Blais Lecours P, Duchaine C, Taillefer M, Tremblay C, Veillette M, Cormier Y, Marsolais D.

PLoS One. 2011;6(8):e23326. doi: 10.1371/journal.pone.0023326. Epub 2011 Aug 12.


The endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: critical role of its hydrolysis and de novo leukotriene B4 biosynthesis.

Chouinard F, Lefebvre JS, Navarro P, Bouchard L, Ferland C, Lalancette-Hébert M, Marsolais D, Laviolette M, Flamand N.

J Immunol. 2011 Mar 1;186(5):3188-96. doi: 10.4049/jimmunol.1002853. Epub 2011 Jan 28.


Modulation of chemokines and allergic airway inflammation by selective local sphingosine-1-phosphate receptor 1 agonism in lungs.

Marsolais D, Yagi S, Kago T, Leaf N, Rosen H.

Mol Pharmacol. 2011 Jan;79(1):61-8. doi: 10.1124/mol.110.066811. Epub 2010 Oct 8.


Treatment with a sphingosine analog does not alter the outcome of a persistent virus infection.

Walsh KB, Marsolais D, Welch MJ, Rosen H, Oldstone MB.

Virology. 2010 Feb 20;397(2):260-9. doi: 10.1016/j.virol.2009.08.043. Epub 2009 Dec 3.


Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules.

Marsolais D, Rosen H.

Nat Rev Drug Discov. 2009 Apr;8(4):297-307. doi: 10.1038/nrd2356. Epub 2009 Mar 20. Review.


A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection.

Marsolais D, Hahm B, Walsh KB, Edelmann KH, McGavern D, Hatta Y, Kawaoka Y, Rosen H, Oldstone MB.

Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1560-5. doi: 10.1073/pnas.0812689106. Epub 2009 Jan 21.


Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions.

Gonzalez-Cabrera PJ, Jo E, Sanna MG, Brown S, Leaf N, Marsolais D, Schaeffer MT, Chapman J, Cameron M, Guerrero M, Roberts E, Rosen H.

Mol Pharmacol. 2008 Nov;74(5):1308-18. doi: 10.1124/mol.108.049783. Epub 2008 Aug 15.


Modulating tone: the overture of S1P receptor immunotherapeutics.

Rosen H, Gonzalez-Cabrera P, Marsolais D, Cahalan S, Don AS, Sanna MG.

Immunol Rev. 2008 Jun;223:221-35. doi: 10.1111/j.1600-065X.2008.00645.x. Review.


Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza.

Marsolais D, Hahm B, Edelmann KH, Walsh KB, Guerrero M, Hatta Y, Kawaoka Y, Roberts E, Oldstone MB, Rosen H.

Mol Pharmacol. 2008 Sep;74(3):896-903. doi: 10.1124/mol.108.048769. Epub 2008 Jun 24.


Inflammatory cells do not decrease the ultimate tensile strength of intact tendons in vivo and in vitro: protective role of mechanical loading.

Marsolais D, Duchesne E, Côté CH, Frenette J.

J Appl Physiol (1985). 2007 Jan;102(1):11-7. Epub 2006 Aug 17.


Pifithrin-alpha, an inhibitor of p53 transactivation, alters the inflammatory process and delays tendon healing following acute injury.

Marsolais D, Côté CH, Frenette J.

Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R321-7. Epub 2006 Aug 10.


Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H.

Nat Chem Biol. 2006 Aug;2(8):434-41. Epub 2006 Jul 9.


[Inflammation and tendon healing].

Marsolais D, Frenette J.

Med Sci (Paris). 2005 Feb;21(2):181-6. Review. French.


Macrophages, not neutrophils, infiltrate skeletal muscle in mice deficient in P/E selectins after mechanical reloading.

Frenette J, Chbinou N, Godbout C, Marsolais D, Frenette PS.

Am J Physiol Regul Integr Comp Physiol. 2003 Oct;285(4):R727-32. Epub 2003 Jun 26.


Neutrophils and macrophages accumulate sequentially following Achilles tendon injury.

Marsolais D, Côté CH, Frenette J.

J Orthop Res. 2001 Nov;19(6):1203-9.

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