Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 156


Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy.

Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, Boehnke K, Baquero C, Hui YH, Chapman SC, Yang Y, Zeng Y, Bogner SM, Foreman RT, Capen A, Donoho GP, Van Horn RD, Barnard DS, Dempsey JA, Beckmann RP, Marshall MS, Chio LC, Qian Y, Webster YW, Aggarwal A, Chu S, Bhattachar S, Stancato LF, Dowless MS, Iversen PW, Manro JR, Walgren JL, Halstead BW, Dieter MZ, Martinez R, Bhagwat SV, Kreklau EL, Lallena MJ, Ye XS, Patel BKR, Reinhard C, Plowman GD, Barda DA, Henry JR, Buchanan SG, Campbell RM.

Mol Cancer Ther. 2019 Dec;18(12):2207-2219. doi: 10.1158/1535-7163.MCT-18-0529. Epub 2019 Sep 17.


HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome.

Asquith M, Sternes PR, Costello ME, Karstens L, Diamond S, Martin TM, Li Z, Marshall MS, Spector TD, le Cao KA, Rosenbaum JT, Brown MA.

Arthritis Rheumatol. 2019 Oct;71(10):1642-1650. doi: 10.1002/art.40917. Epub 2019 Aug 12.


Inhibition of the IGF-1-PI3K-Akt-mTORC2 pathway in lipid rafts increases neuronal vulnerability in a genetic lysosomal glycosphingolipidosis.

Sural-Fehr T, Singh H, Cantuti-Catelvetri L, Zhu H, Marshall MS, Rebiai R, Jastrzebski MJ, Givogri MI, Rasenick MM, Bongarzone ER.

Dis Model Mech. 2019 May 23;12(5). pii: dmm036590. doi: 10.1242/dmm.036590.


α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies.

Abdelkarim H, Marshall MS, Scesa G, Smith RA, Rue E, Marshall J, Elackattu V, Stoskute M, Issa Y, Santos M, Nguyen D, Hauck Z, van Breemen R, Celej MS, Gaponenko V, Bongarzone ER.

Sci Rep. 2018 Aug 20;8(1):12462. doi: 10.1038/s41598-018-30808-9.


Analysis of age-related changes in psychosine metabolism in the human brain.

Marshall MS, Jakubauskas B, Bogue W, Stoskute M, Hauck Z, Rue E, Nichols M, DiAntonio LL, van Breemen RB, Kordower JH, Saavedra-Matiz CA, Bongarzone ER.

PLoS One. 2018 Feb 26;13(2):e0193438. doi: 10.1371/journal.pone.0193438. eCollection 2018.


Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.

Marshall MS, Issa Y, Jakubauskas B, Stoskute M, Elackattu V, Marshall JN, Bogue W, Nguyen D, Hauck Z, Rue E, Karumuthil-Melethil S, Zaric V, Bosland M, van Breemen RB, Givogri MI, Gray SJ, Crocker SJ, Bongarzone ER.

Mol Ther. 2018 Mar 7;26(3):874-889. doi: 10.1016/j.ymthe.2018.01.009. Epub 2018 Jan 17.


microRNA-219 Reduces Viral Load and Pathologic Changes in Theiler's Virus-Induced Demyelinating Disease.

Moyano AL, Steplowski J, Wang H, Son KN, Rapolti DI, Marshall J, Elackattu V, Marshall MS, Hebert AK, Reiter CR, Ulloa V, Pituch KC, Givogri MI, Lu QR, Lipton HL, Bongarzone ER.

Mol Ther. 2018 Mar 7;26(3):730-743. doi: 10.1016/j.ymthe.2018.01.008. Epub 2018 Jan 17.


AAVrh10 Gene Therapy Ameliorates Central and Peripheral Nervous System Disease in Canine Globoid Cell Leukodystrophy (Krabbe Disease).

Bradbury AM, Rafi MA, Bagel JH, Brisson BK, Marshall MS, Pesayco Salvador J, Jiang X, Swain GP, Prociuk ML, ODonnell PA, Fitzgerald C, Ory DS, Bongarzone ER, Shelton GD, Wenger DA, Vite CH.

Hum Gene Ther. 2018 Jul;29(7):785-801. doi: 10.1089/hum.2017.151. Epub 2018 Mar 14.


Controlling Mobility in Perovskite Oxides by Ferroelectric Modulation of Atomic-Scale Interface Structure.

Malashevich A, Marshall MSJ, Visani C, Disa AS, Xu H, Walker FJ, Ahn CH, Ismail-Beigi S.

Nano Lett. 2018 Jan 10;18(1):573-578. doi: 10.1021/acs.nanolett.7b04715. Epub 2017 Dec 26.


The BioFragment Database (BFDb): An open-data platform for computational chemistry analysis of noncovalent interactions.

Burns LA, Faver JC, Zheng Z, Marshall MS, Smith DGA, Vanommeslaeghe K, MacKerell AD Jr, Merz KM Jr, Sherrill CD.

J Chem Phys. 2017 Oct 28;147(16):161727. doi: 10.1063/1.5001028.


Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe's disease.

D'Auria L, Reiter C, Ward E, Moyano AL, Marshall MS, Nguyen D, Scesa G, Hauck Z, van Breemen R, Givogri MI, Bongarzone ER.

PLoS One. 2017 May 22;12(5):e0178103. doi: 10.1371/journal.pone.0178103. eCollection 2017.


Homozygous variant in C21orf2 in a case of Jeune syndrome with severe thoracic involvement: Extending the phenotypic spectrum.

McInerney-Leo AM, Wheeler L, Marshall MS, Anderson LK, Zankl A, Brown MA, Leo PJ, Wicking C, Duncan EL.

Am J Med Genet A. 2017 Jun;173(6):1698-1704. doi: 10.1002/ajmg.a.38215. Epub 2017 Apr 19.


Electron-beam-induced-current and active secondary-electron voltage-contrast with aberration-corrected electron probes.

Han MG, Garlow JA, Marshall MSJ, Tiano AL, Wong SS, Cheong SW, Walker FJ, Ahn CH, Zhu Y.

Ultramicroscopy. 2017 May;176:80-85. doi: 10.1016/j.ultramic.2017.03.028. Epub 2017 Mar 23.


Electron-beam-induced-current and active secondary-electron voltage-contrast with aberration-corrected electron probes.

Han MG, Garlow JA, Marshall MS, Tiano AL, Wong SS, Cheong SW, Walker FJ, Ahn CH, Zhu Y.

Ultramicroscopy. 2017 Jun;177:14-19. doi: 10.1016/j.ultramic.2017.01.016. Epub 2017 Feb 6.


Intrathecal administration of AAV/GALC vectors in 10-11-day-old twitcher mice improves survival and is enhanced by bone marrow transplant.

Karumuthil-Melethil S, Marshall MS, Heindel C, Jakubauskas B, Bongarzone ER, Gray SJ.

J Neurosci Res. 2016 Nov;94(11):1138-51. doi: 10.1002/jnr.23882.


The health care and life sciences community profile for dataset descriptions.

Dumontier M, Gray AJG, Marshall MS, Alexiev V, Ansell P, Bader G, Baran J, Bolleman JT, Callahan A, Cruz-Toledo J, Gaudet P, Gombocz EA, Gonzalez-Beltran AN, Groth P, Haendel M, Ito M, Jupp S, Juty N, Katayama T, Kobayashi N, Krishnaswami K, Laibe C, Le Novère N, Lin S, Malone J, Miller M, Mungall CJ, Rietveld L, Wimalaratne SM, Yamaguchi A.

PeerJ. 2016 Aug 16;4:e2331. doi: 10.7717/peerj.2331. eCollection 2016.


Accurate Ionization Potentials and Electron Affinities of Acceptor Molecules I. Reference Data at the CCSD(T) Complete Basis Set Limit.

Richard RM, Marshall MS, Dolgounitcheva O, Ortiz JV, Brédas JL, Marom N, Sherrill CD.

J Chem Theory Comput. 2016 Feb 9;12(2):595-604. doi: 10.1021/acs.jctc.5b00875. Epub 2016 Jan 25.


Case Study for Integration of an Oncology Clinical Site in a Semantic Interoperability Solution based on HL7 v3 and SNOMED-CT: Data Transformation Needs.

Ibrahim A, Bucur A, Perez-Rey D, Alonso E, de Hoog M, Dekker A, Marshall MS.

AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:71. eCollection 2015.


LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms.

King C, Diaz HB, McNeely S, Barnard D, Dempsey J, Blosser W, Beckmann R, Barda D, Marshall MS.

Mol Cancer Ther. 2015 Sep;14(9):2004-13. doi: 10.1158/1535-7163.MCT-14-1037. Epub 2015 Jul 3.


Rubrene: The Interplay between Intramolecular and Intermolecular Interactions Determines the Planarization of Its Tetracene Core in the Solid State.

Sutton C, Marshall MS, Sherrill CD, Risko C, Brédas JL.

J Am Chem Soc. 2015 Jul 15;137(27):8775-82. doi: 10.1021/jacs.5b04066. Epub 2015 Jul 2.


Whole exome sequencing is an efficient, sensitive and specific method for determining the genetic cause of short-rib thoracic dystrophies.

McInerney-Leo AM, Harris JE, Leo PJ, Marshall MS, Gardiner B, Kinning E, Leong HY, McKenzie F, Ong WP, Vodopiutz J, Wicking C, Brown MA, Zankl A, Duncan EL.

Clin Genet. 2015 Dec;88(6):550-7. doi: 10.1111/cge.12550. Epub 2015 Feb 17.


Compound heterozygous mutations in RIPPLY2 associated with vertebral segmentation defects.

McInerney-Leo AM, Sparrow DB, Harris JE, Gardiner BB, Marshall MS, O'Reilly VC, Shi H, Brown MA, Leo PJ, Zankl A, Dunwoodie SL, Duncan EL.

Hum Mol Genet. 2015 Mar 1;24(5):1234-42. doi: 10.1093/hmg/ddu534. Epub 2014 Oct 24.


Towards a semantic PACS: Using Semantic Web technology to represent imaging data.

Van Soest J, Lustberg T, Grittner D, Marshall MS, Persoon L, Nijsten B, Feltens P, Dekker A.

Stud Health Technol Inform. 2014;205:166-70.


Reversible modulation of orbital occupations via an interface-induced polar state in metallic manganites.

Chen H, Qiao Q, Marshall MS, Georgescu AB, Gulec A, Phillips PJ, Klie RF, Walker FJ, Ahn CH, Ismail-Beigi S.

Nano Lett. 2014 Sep 10;14(9):4965-70. doi: 10.1021/nl501209p. Epub 2014 Aug 28.


Interface-induced nonswitchable domains in ferroelectric thin films.

Han MG, Marshall MS, Wu L, Schofield MA, Aoki T, Twesten R, Hoffman J, Walker FJ, Ahn CH, Zhu Y.

Nat Commun. 2014 Aug 18;5:4693. doi: 10.1038/ncomms5693.


Communication: resolving the three-body contribution to the lattice energy of crystalline benzene: benchmark results from coupled-cluster theory.

Kennedy MR, McDonald AR, DePrince AE 3rd, Marshall MS, Podeszwa R, Sherrill CD.

J Chem Phys. 2014 Mar 28;140(12):121104. doi: 10.1063/1.4869686.


Scanning tunnelling microscopy of epitaxial nanostructures.

Marshall MS, Castell MR.

Chem Soc Rev. 2014 Apr 7;43(7):2226-39. doi: 10.1039/c3cs60458f. Epub 2014 Feb 7.


Whole exome sequencing is an efficient, sensitive and specific method of mutation detection in osteogenesis imperfecta and Marfan syndrome.

McInerney-Leo AM, Marshall MS, Gardiner B, Coucke PJ, Van Laer L, Loeys BL, Summers KM, Symoens S, West JA, West MJ, Paul Wordsworth B, Zankl A, Leo PJ, Brown MA, Duncan EL.

Bonekey Rep. 2013 Dec 4;2:456. doi: 10.1038/bonekey.2013.190. eCollection 2013.


BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains.

Katayama T, Wilkinson MD, Aoki-Kinoshita KF, Kawashima S, Yamamoto Y, Yamaguchi A, Okamoto S, Kawano S, Kim JD, Wang Y, Wu H, Kano Y, Ono H, Bono H, Kocbek S, Aerts J, Akune Y, Antezana E, Arakawa K, Aranda B, Baran J, Bolleman J, Bonnal RJ, Buttigieg PL, Campbell MP, Chen YA, Chiba H, Cock PJ, Cohen KB, Constantin A, Duck G, Dumontier M, Fujisawa T, Fujiwara T, Goto N, Hoehndorf R, Igarashi Y, Itaya H, Ito M, Iwasaki W, Kalaš M, Katoda T, Kim T, Kokubu A, Komiyama Y, Kotera M, Laibe C, Lapp H, Lütteke T, Marshall MS, Mori T, Mori H, Morita M, Murakami K, Nakao M, Narimatsu H, Nishide H, Nishimura Y, Nystrom-Persson J, Ogishima S, Okamura Y, Okuda S, Oshita K, Packer NH, Prins P, Ranzinger R, Rocca-Serra P, Sansone S, Sawaki H, Shin SH, Splendiani A, Strozzi F, Tadaka S, Toukach P, Uchiyama I, Umezaki M, Vos R, Whetzel PL, Yamada I, Yamasaki C, Yamashita R, York WS, Zmasek CM, Kawamoto S, Takagi T.

J Biomed Semantics. 2014 Feb 5;5(1):5. doi: 10.1186/2041-1480-5-5.


Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.

Smith BR, Santos MB, Marshall MS, Cantuti-Castelvetri L, Lopez-Rosas A, Li G, van Breemen R, Claycomb KI, Gallea JI, Celej MS, Crocker SJ, Givogri MI, Bongarzone ER.

J Pathol. 2014 Apr;232(5):509-21. doi: 10.1002/path.4328. Epub 2014 Feb 20.


Comparing Counterpoise-Corrected, Uncorrected, and Averaged Binding Energies for Benchmarking Noncovalent Interactions.

Burns LA, Marshall MS, Sherrill CD.

J Chem Theory Comput. 2014 Jan 14;10(1):49-57. doi: 10.1021/ct400149j. Epub 2013 Dec 13. No abstract available.


Whole exome sequencing is an efficient and sensitive method for detection of germline mutations in patients with phaeochromcytomas and paragangliomas.

McInerney-Leo AM, Marshall MS, Gardiner B, Benn DE, McFarlane J, Robinson BG, Brown MA, Leo PJ, Clifton-Bligh RJ, Duncan EL.

Clin Endocrinol (Oxf). 2014 Jan;80(1):25-33. doi: 10.1111/cen.12331. Epub 2013 Oct 25.


An RDF/OWL knowledge base for query answering and decision support in clinical pharmacogenetics.

Samwald M, Freimuth R, Luciano JS, Lin S, Powers RL, Marshall MS, Adlassnig KP, Dumontier M, Boyce RD.

Stud Health Technol Inform. 2013;192:539-42.


c(4 × 2) and related structural units on the SrTiO3(001) surface: scanning tunneling microscopy, density functional theory, and atomic structure.

Becerra-Toledo AE, Marshall MS, Castell MR, Marks LD.

J Chem Phys. 2012 Jun 7;136(21):214701. doi: 10.1063/1.4719212.


Translating standards into practice - one Semantic Web API for Gene Expression.

Deus HF, Prud'hommeaux E, Miller M, Zhao J, Malone J, Adamusiak T, McCusker J, Das S, Rocca Serra P, Fox R, Marshall MS.

J Biomed Inform. 2012 Aug;45(4):782-94. doi: 10.1016/j.jbi.2012.03.002. Epub 2012 Mar 24.


Semantic Web applications and tools for the life sciences: SWAT4LS 2010.

Burger A, Paschke A, Romano P, Marshall MS, Splendiani A.

BMC Bioinformatics. 2012 Jan 25;13 Suppl 1:S1. doi: 10.1186/1471-2105-13-S1-S1.


Semantically enabling pharmacogenomic data for the realization of personalized medicine.

Samwald M, Coulet A, Huerga I, Powers RL, Luciano JS, Freimuth RR, Whipple F, Pichler E, Prud'hommeaux E, Dumontier M, Marshall MS.

Pharmacogenomics. 2012 Jan;13(2):201-12. doi: 10.2217/pgs.11.179. Review. Erratum in: Pharmacogenomics. 2012 Apr;13(5):628.


Dispersion-Weighted Explicitly Correlated Coupled-Cluster Theory [DW-CCSD(T**)-F12].

Marshall MS, Sherrill CD.

J Chem Theory Comput. 2011 Dec 13;7(12):3978-82. doi: 10.1021/ct200600p. Epub 2011 Nov 2.


Empowering industrial research with shared biomedical vocabularies.

Harland L, Larminie C, Sansone SA, Popa S, Marshall MS, Braxenthaler M, Cantor M, Filsell W, Forster MJ, Huang E, Matern A, Musen M, Saric J, Slater T, Wilson J, Lynch N, Wise J, Dix I.

Drug Discov Today. 2011 Nov;16(21-22):940-7. doi: 10.1016/j.drudis.2011.09.013. Epub 2011 Sep 23. Review.


Surface and defect structure of oxide nanowires on SrTiO3.

Marshall MS, Becerra-Toledo AE, Marks LD, Castell MR.

Phys Rev Lett. 2011 Aug 19;107(8):086102. Epub 2011 Aug 16.


Towards an interoperable information infrastructure providing decision support for genomic medicine.

Samwald M, Stenzhorn H, Dumontier M, Marshall MS, Luciano J, Adlassnig KP.

Stud Health Technol Inform. 2011;169:165-9.


Formal Estimation of Errors in Computed Absolute Interaction Energies of Protein-ligand Complexes.

Faver JC, Benson ML, He X, Roberts BP, Wang B, Marshall MS, Kennedy MR, Sherrill CD, Merz KM Jr.

J Chem Theory Comput. 2011 Mar 8;7(3):790-797.


Linked open drug data for pharmaceutical research and development.

Samwald M, Jentzsch A, Bouton C, Kallesøe CS, Willighagen E, Hajagos J, Marshall MS, Prud'hommeaux E, Hassenzadeh O, Pichler E, Stephens S.

J Cheminform. 2011 May 16;3(1):19. doi: 10.1186/1758-2946-3-19.


The energy computation paradox and ab initio protein folding.

Faver JC, Benson ML, He X, Roberts BP, Wang B, Marshall MS, Sherrill CD, Merz KM Jr.

PLoS One. 2011 Apr 25;6(4):e18868. doi: 10.1371/journal.pone.0018868.


Biomedical semantics in the Semantic Web.

Splendiani A, Burger A, Paschke A, Romano P, Marshall MS.

J Biomed Semantics. 2011 Mar 7;2 Suppl 1:S1. doi: 10.1186/2041-1480-2-S1-S1.


Interpersonal Violence.

Rosenberg ML, Butchart A, Mercy J, Narasimhan V, Waters H, Marshall MS.

In: Jamison DT, Breman JG, Measham AR, Alleyne G, Claeson M, Evans DB, Jha P, Mills A, Musgrove P, editors. Disease Control Priorities in Developing Countries. 2nd edition. Washington (DC): World Bank; 2006. Chapter 40.


Integrating findings of traditional medicine with modern pharmaceutical research: the potential role of linked open data.

Samwald M, Dumontier M, Zhao J, Luciano JS, Marshall MS, Cheung K.

Chin Med. 2010 Dec 17;5:43. doi: 10.1186/1749-8546-5-43.

Supplemental Content

Loading ...
Support Center