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Items: 45


Exercise ameliorates endoplasmic reticulum stress-mediated vascular dysfunction in mesenteric arteries in atherosclerosis.

Hong J, Kim K, Park E, Lee J, Markofski MM, Marrelli SP, Park Y.

Sci Rep. 2018 May 21;8(1):7938. doi: 10.1038/s41598-018-26188-9.


Sex Differences in Adipose Tissue CD8+ T Cells and Regulatory T Cells in Middle-Aged Mice.

Ahnstedt H, Roy-O'Reilly M, Spychala MS, Mobley AS, Bravo-Alegria J, Chauhan A, Aronowski J, Marrelli SP, McCullough LD.

Front Immunol. 2018 Apr 4;9:659. doi: 10.3389/fimmu.2018.00659. eCollection 2018.


A novel reporter allele for monitoring Dll4 expression within the embryonic and adult mouse.

Herman AM, Rhyner AM, Devine WP, Marrelli SP, Bruneau BG, Wythe JD.

Biol Open. 2018 Mar 12;7(3). pii: bio026799. doi: 10.1242/bio.026799.


TRPV1-mediated Pharmacological Hypothermia Promotes Improved Functional Recovery Following Ischemic Stroke.

Cao Z, Balasubramanian A, Pedersen SE, Romero J, Pautler RG, Marrelli SP.

Sci Rep. 2017 Dec 15;7(1):17685. doi: 10.1038/s41598-017-17548-y.


KIR channels tune electrical communication in cerebral arteries.

Sancho M, Samson NC, Hald BO, Hashad AM, Marrelli SP, Brett SE, Welsh DG.

J Cereb Blood Flow Metab. 2017 Jun;37(6):2171-2184. doi: 10.1177/0271678X16662041. Epub 2016 Jan 1.


Induction of therapeutic hypothermia by pharmacological modulation of temperature-sensitive TRP channels: theoretical framework and practical considerations.

Feketa VV, Marrelli SP.

Temperature (Austin). 2015 Apr 27;2(2):244-57. doi: 10.1080/23328940.2015.1024383. eCollection 2015 Apr-Jun. Review.


Systemic Administration of the TRPV3 Ion Channel Agonist Carvacrol Induces Hypothermia in Conscious Rodents.

Feketa VV, Marrelli SP.

PLoS One. 2015 Nov 3;10(11):e0141994. doi: 10.1371/journal.pone.0141994. eCollection 2015.


Transient receptor potential melastatin 8 channel inhibition potentiates the hypothermic response to transient receptor potential vanilloid 1 activation in the conscious mouse.

Feketa VV, Zhang Y, Cao Z, Balasubramanian A, Flores CM, Player MR, Marrelli SP.

Crit Care Med. 2014 May;42(5):e355-63. doi: 10.1097/CCM.0000000000000229.


Pharmacologically induced hypothermia via TRPV1 channel agonism provides neuroprotection following ischemic stroke when initiated 90 min after reperfusion.

Cao Z, Balasubramanian A, Marrelli SP.

Am J Physiol Regul Integr Comp Physiol. 2014 Jan 15;306(2):R149-56. doi: 10.1152/ajpregu.00329.2013. Epub 2013 Dec 4.


Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition.

Feketa VV, Balasubramanian A, Flores CM, Player MR, Marrelli SP.

Am J Physiol Regul Integr Comp Physiol. 2013 Nov 1;305(9):R1040-50. doi: 10.1152/ajpregu.00296.2013. Epub 2013 Sep 4.


A new rodent model for obstructive sleep apnea: effects on ATP-mediated dilations in cerebral arteries.

Crossland RF, Durgan DJ, Lloyd EE, Phillips SC, Reddy AK, Marrelli SP, Bryan RM Jr.

Am J Physiol Regul Integr Comp Physiol. 2013 Aug 15;305(4):R334-42. doi: 10.1152/ajpregu.00244.2013. Epub 2013 Jun 12.


Endothelium-dependent relaxations in the aorta from K(2p)6.1 knockout mice.

Lloyd EE, Pandit LM, Crossland RF, Marrelli SP, Bryan RM Jr.

Am J Physiol Regul Integr Comp Physiol. 2013 Jul 1;305(1):R60-7. doi: 10.1152/ajpregu.00126.2013. Epub 2013 May 1.


Role of TRPC1 and TRPC3 channels in contraction and relaxation of mouse thoracic aorta.

Kochukov MY, Balasubramanian A, Noel RC, Marrelli SP.

J Vasc Res. 2013;50(1):11-20. doi: 10.1159/000342461. Epub 2012 Oct 23.


Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity.

Senadheera S, Kim Y, Grayson TH, Toemoe S, Kochukov MY, Abramowitz J, Housley GD, Bertrand RL, Chadha PS, Bertrand PP, Murphy TV, Tare M, Birnbaumer L, Marrelli SP, Sandow SL.

Cardiovasc Res. 2012 Sep 1;95(4):439-47. doi: 10.1093/cvr/cvs208. Epub 2012 Jun 21.


Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice.

Lloyd EE, Crossland RF, Phillips SC, Marrelli SP, Reddy AK, Taffet GE, Hartley CJ, Bryan RM Jr.

Hypertension. 2011 Oct;58(4):672-8. doi: 10.1161/HYPERTENSIONAHA.111.175349. Epub 2011 Aug 29.


Upregulated TRPC3 and Downregulated TRPC1 Channel Expression during Hypertension is Associated with Increased Vascular Contractility in Rat.

Noorani MM, Noel RC, Marrelli SP.

Front Physiol. 2011 Jul 22;2:42. doi: 10.3389/fphys.2011.00042. eCollection 2011.


Endothelium-dependent hyperpolarization: out of the dish and into the brain.

Bryan RM Jr, Marrelli SP.

J Cereb Blood Flow Metab. 2011 May;31(5):1173-4. doi: 10.1038/jcbfm.2010.221. Epub 2010 Dec 22. No abstract available.


Cerebrovascular responses in mice deficient in the potassium channel, TREK-1.

Namiranian K, Lloyd EE, Crossland RF, Marrelli SP, Taffet GE, Reddy AK, Hartley CJ, Bryan RM Jr.

Am J Physiol Regul Integr Comp Physiol. 2010 Aug;299(2):R461-9. doi: 10.1152/ajpregu.00057.2010. Epub 2010 Mar 31.


Characterization of TWIK-2, a two-pore domain K+ channel, cloned from the rat middle cerebral artery.

Lloyd EE, Marrelli SP, Namiranian K, Bryan RM Jr.

Exp Biol Med (Maywood). 2009 Dec;234(12):1493-502. doi: 10.3181/0903-RM-110.


Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation.

Chen J, Crossland RF, Noorani MM, Marrelli SP.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H417-24. doi: 10.1152/ajpheart.01130.2008. Epub 2009 Jun 5.


cGMP does not activate two-pore domain K+ channels in cerebrovascular smooth muscle.

Lloyd EE, Marrelli SP, Bryan RM Jr.

Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1774-80. doi: 10.1152/ajpheart.00082.2009. Epub 2009 Apr 10.


Erythropoietin potentiates EDHF-mediated dilations in rat middle cerebral arteries.

Shafi NI, Andresen J, Marrelli SP, Bryan RM Jr.

J Neurotrauma. 2008 Mar;25(3):257-65. doi: 10.1089/neu.2007.0347.


KIR channels function as electrical amplifiers in rat vascular smooth muscle.

Smith PD, Brett SE, Luykenaar KD, Sandow SL, Marrelli SP, Vigmond EJ, Welsh DG.

J Physiol. 2008 Feb 15;586(4):1147-60. Epub 2007 Dec 6.


Myoendothelial gap junction frequency does not account for sex differences in EDHF responses in rat MCA.

Sokoya EM, Burns AR, Marrelli SP, Chen J.

Microvasc Res. 2007 Jul;74(1):39-44. Epub 2007 Apr 6.


PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries.

Marrelli SP, O'neil RG, Brown RC, Bryan RM Jr.

Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1390-7. Epub 2006 Oct 27.


Evidence for two-pore domain potassium channels in rat cerebral arteries.

Bryan RM Jr, You J, Phillips SC, Andresen JJ, Lloyd EE, Rogers PA, Dryer SE, Marrelli SP.

Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H770-80. Epub 2006 Mar 24.


Endothelium-derived hyperpolarizing factor: a cousin to nitric oxide and prostacyclin.

Bryan RM Jr, You J, Golding EM, Marrelli SP.

Anesthesiology. 2005 Jun;102(6):1261-77. Review.


Role of endothelial intermediate conductance KCa channels in cerebral EDHF-mediated dilations.

Marrelli SP, Eckmann MS, Hunte MS.

Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1590-9. Epub 2003 Jun 12.


Role of cytoplasmic phospholipase A2 in endothelium-derived hyperpolarizing factor dilations of rat middle cerebral arteries.

You J, Marrelli SP, Bryan RM Jr.

J Cereb Blood Flow Metab. 2002 Oct;22(10):1239-47.


Endothelium-derived hyperpolarizing factor in the brain: a new regulator of cerebral blood flow?

Golding EM, Marrelli SP, You J, Bryan RM Jr.

Stroke. 2002 Mar;33(3):661-3. No abstract available.


Role of endothelium in shear stress-induced constrictions in rat middle cerebral artery.

Bryan RM Jr, Steenberg ML, Marrelli SP.

Stroke. 2001 Jun;32(6):1394-400.


Effects of luminal shear stress on cerebral arteries and arterioles.

Bryan RM Jr, Marrelli SP, Steenberg ML, Schildmeyer LA, Johnson TD.

Am J Physiol Heart Circ Physiol. 2001 May;280(5):H2011-22.


Functional heterogeneity of endothelial P2 purinoceptors in the cerebrovascular tree of the rat.

You J, Johnson TD, Marrelli SP, Bryan RM Jr.

Am J Physiol. 1999 Sep;277(3 Pt 2):H893-900.


P2 purinoceptor-mediated dilations in the rat middle cerebral artery after ischemia-reperfusion.

Marrelli SP, Khorovets A, Johnson TD, Childres WF, Bryan RM Jr.

Am J Physiol. 1999 Jan;276(1 Pt 2):H33-41.


Endothelial-mediated dilations following severe controlled cortical impact injury in the rat middle cerebral artery.

Golding EM, Steenberg ML, Cherian L, Marrelli SP, Robertson CS, Bryan RM Jr.

J Neurotrauma. 1998 Aug;15(8):635-44.


Altered function of inward rectifier potassium channels in cerebrovascular smooth muscle after ischemia/reperfusion.

Marrelli SP, Johnson TD, Khorovets A, Childres WF, Bryan RM Jr.

Stroke. 1998 Jul;29(7):1469-74.


Inward rectifier potassium channels in the rat middle cerebral artery.

Johnson TD, Marrelli SP, Steenberg ML, Childres WF, Bryan RM Jr.

Am J Physiol. 1998 Feb;274(2 Pt 2):R541-7.


Molecular evidence for a vascular smooth muscle H+-K+-ATPase.

Marrelli SP, Zhao X, Allen JC.

Am J Physiol. 1997 Feb;272(2 Pt 2):H869-74.


Acute L-triiodothyronine administration potentiates inotropic responses to beta-adrenergic stimulation in the isolated perfused rat heart.

Tielens ET, Forder JR, Chatham JC, Marrelli SP, Ladenson PW.

Cardiovasc Res. 1996 Aug;32(2):306-10.


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