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Items: 34


The Metastasis Suppressor Protein Nme1 Is a Concentration-Dependent Modulator of Ca2+/Calmodulin-Dependent Protein Kinase II.

Royer L, Shangraw K, Herzog JJ, Pouvreau S, Marr MT 2nd, Paradis S.

Biochemistry. 2019 Jun 18;58(24):2710-2714. doi: 10.1021/acs.biochem.9b00121. Epub 2019 Jun 4.


The Ras-like GTPase Rem2 is a potent inhibitor of calcium/calmodulin-dependent kinase II activity.

Royer L, Herzog JJ, Kenny K, Tzvetkova B, Cochrane JC, Marr MT 2nd, Paradis S.

J Biol Chem. 2018 Sep 21;293(38):14798-14811. doi: 10.1074/jbc.RA118.003560. Epub 2018 Aug 2.


The GCN2-ATF4 Signaling Pathway Induces 4E-BP to Bias Translation and Boost Antimicrobial Peptide Synthesis in Response to Bacterial Infection.

Vasudevan D, Clark NK, Sam J, Cotham VC, Ueberheide B, Marr MT 2nd, Ryoo HD.

Cell Rep. 2017 Nov 21;21(8):2039-2047. doi: 10.1016/j.celrep.2017.10.096.


Rem2 signaling affects neuronal structure and function in part by regulation of gene expression.

Kenny K, Royer L, Moore AR, Chen X, Marr MT 2nd, Paradis S.

Mol Cell Neurosci. 2017 Dec;85:190-201. doi: 10.1016/j.mcn.2017.10.004. Epub 2017 Oct 21.


4E-BP is a target of the GCN2-ATF4 pathway during Drosophila development and aging.

Kang MJ, Vasudevan D, Kang K, Kim K, Park JE, Zhang N, Zeng X, Neubert TA, Marr MT 2nd, Ryoo HD.

J Cell Biol. 2017 Jan 2;216(1):115-129. doi: 10.1083/jcb.201511073. Epub 2016 Dec 15.


dFOXO Activates Large and Small Heat Shock Protein Genes in Response to Oxidative Stress to Maintain Proteostasis in Drosophila.

Donovan MR, Marr MT 2nd.

J Biol Chem. 2016 Sep 2;291(36):19042-50. doi: 10.1074/jbc.M116.723049. Epub 2016 Jul 19.


Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling.

Coffey RT, Shi Y, Long MJ, Marr MT 2nd, Hedstrom L.

J Biol Chem. 2016 Mar 4;291(10):5221-33. doi: 10.1074/jbc.M115.691584. Epub 2016 Jan 6.


FOXO regulates RNA interference in Drosophila and protects from RNA virus infection.

Spellberg MJ, Marr MT 2nd.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14587-92. doi: 10.1073/pnas.1517124112. Epub 2015 Nov 9.


The insulin receptor cellular IRES confers resistance to eIF4A inhibition.

Olson CM, Donovan MR, Spellberg MJ, Marr MT 2nd.

Elife. 2013 Jul 16;2:e00542. doi: 10.7554/eLife.00542.


Holo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription.

Pennington KL, Marr SK, Chirn GW, Marr MT 2nd.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7678-83. doi: 10.1073/pnas.1221712110. Epub 2013 Apr 22.


CaMKII-dependent phosphorylation of the GTPase Rem2 is required to restrict dendritic complexity.

Ghiretti AE, Kenny K, Marr MT 2nd, Paradis S.

J Neurosci. 2013 Apr 10;33(15):6504-15. doi: 10.1523/JNEUROSCI.3861-12.2013.


Single nucleotide in the MTF-1 binding site can determine metal-specific transcription activation.

Sims HI, Chirn GW, Marr MT 2nd.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16516-21. doi: 10.1073/pnas.1207737109. Epub 2012 Sep 24.


Efficient metal-specific transcription activation by Drosophila MTF-1 requires conserved cysteine residues in the carboxy-terminal domain.

Marr SK, Pennington KL, Marr MT.

Biochim Biophys Acta. 2012 Aug;1819(8):902-12. doi: 10.1016/j.bbagrm.2012.03.005. Epub 2012 Mar 28.


Seasonality of brown recluse populations is reflected by numbers of brown recluse envenomations.

Rader RK, Stoecker WV, Malters JM, Marr MT, Dyer JA.

Toxicon. 2012 Jul;60(1):1-3. doi: 10.1016/j.toxicon.2012.03.012. Epub 2012 Mar 21.


Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila.

Khodor YL, Rodriguez J, Abruzzi KC, Tang CH, Marr MT 2nd, Rosbash M.

Genes Dev. 2011 Dec 1;25(23):2502-12. doi: 10.1101/gad.178962.111.


Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.

Kadener S, Rodriguez J, Abruzzi KC, Khodor YL, Sugino K, Marr MT 2nd, Nelson S, Rosbash M.

RNA. 2009 Apr;15(4):537-45. doi: 10.1261/rna.1319309. Epub 2009 Feb 17.


TAF4 takes flight.

Marr MT 2nd.

Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1295-6. doi: 10.1073/pnas.0812990106. Epub 2009 Jan 27. No abstract available.


MyoD targets TAF3/TRF3 to activate myogenin transcription.

Deato MD, Marr MT, Sottero T, Inouye C, Hu P, Tjian R.

Mol Cell. 2008 Oct 10;32(1):96-105. doi: 10.1016/j.molcel.2008.09.009.


TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription.

Hsu JY, Juven-Gershon T, Marr MT 2nd, Wright KJ, Tjian R, Kadonaga JT.

Genes Dev. 2008 Sep 1;22(17):2353-8. doi: 10.1101/gad.1681808. Epub 2008 Aug 14.


Characterization of the Drosophila insulin receptor promoter.

Casas-Tinto S, Marr MT 2nd, Andreu P, Puig O.

Biochim Biophys Acta. 2007 Apr;1769(4):236-43. Epub 2007 Mar 16.


IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback.

Marr MT 2nd, D'Alessio JA, Puig O, Tjian R.

Genes Dev. 2007 Jan 15;21(2):175-83.


TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter.

Wright KJ, Marr MT 2nd, Tjian R.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12347-52. Epub 2006 Aug 8.


Coactivator cross-talk specifies transcriptional output.

Marr MT 2nd, Isogai Y, Wright KJ, Tjian R.

Genes Dev. 2006 Jun 1;20(11):1458-69.


Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS.

Adelman K, Marr MT, Werner J, Saunders A, Ni Z, Andrulis ED, Lis JT.

Mol Cell. 2005 Jan 7;17(1):103-12.


Regulatory diversity among metazoan co-activator complexes.

Taatjes DJ, Marr MT, Tjian R.

Nat Rev Mol Cell Biol. 2004 May;5(5):403-10. Review. No abstract available.


Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway.

Puig O, Marr MT, Ruhf ML, Tjian R.

Genes Dev. 2003 Aug 15;17(16):2006-20. Epub 2003 Jul 31.


Restructuring of an RNA polymerase holoenzyme elongation complex by lambdoid phage Q proteins.

Marr MT, Datwyler SA, Meares CF, Roberts JW.

Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):8972-8.


The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized.

Sharp MM, Chan CL, Lu CZ, Marr MT, Nechaev S, Merritt EW, Severinov K, Roberts JW, Gross CA.

Genes Dev. 1999 Nov 15;13(22):3015-26.


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