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Items: 1 to 50 of 82

1.

Non-genotoxic MDM2 inhibition selectively induces pro-apoptotic p53 gene signature in chronic lymphocytic leukemia cells.

Ciardullo C, Aptullahoglu E, Woodhouse L, Lin WY, Wallis JP, Marr H, Marshall S, Bown N, Willmore E, Lunec J.

Haematologica. 2019 Apr 19. pii: haematol.2018.206631. doi: 10.3324/haematol.2018.206631. [Epub ahead of print]

2.

Efficacy of venetoclax monotherapy in patients with relapsed chronic lymphocytic leukaemia in the post-BCR inhibitor setting: a UK wide analysis.

Eyre TA, Kirkwood AA, Gohill S, Follows G, Walewska R, Walter H, Cross M, Forconi F, Shah N, Chasty R, Hart A, Broom A, Marr H, Patten PEM, Dann A, Arumainathan A, Munir T, Shankara P, Bloor A, Johnston R, Orchard K, Schuh AH, Fox CP; the UK CLL Forum.

Br J Haematol. 2019 May;185(4):656-669. doi: 10.1111/bjh.15802. Epub 2019 Feb 15.

PMID:
30768675
3.

Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis.

Schreeg ME, Marr HS, Tarigo JL, Sherrill MK, Outi HK, Scholl EH, Bird DM, Vigil A, Hung C, Nakajima R, Liang L, Trieu A, Doolan DL, Thomas JE, Levy MG, Reichard MV, Felgner PL, Cohn LA, Birkenheuer AJ.

Clin Proteomics. 2018 Dec 29;15:44. doi: 10.1186/s12014-018-9218-9. eCollection 2018.

4.

Babesia gibsoni cytochrome b mutations in canine blood samples submitted to a US veterinary diagnostic laboratory.

Birkenheuer AJ, Marr HS, Wilson JM, Breitschwerdt EB, Qurollo BA.

J Vet Intern Med. 2018 Nov;32(6):1965-1969. doi: 10.1111/jvim.15300. Epub 2018 Oct 11.

5.

Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs.

Neupane P, Hegarty BC, Marr HS, Maggi RG, Birkenheuer AJ, Breitschwerdt EB.

J Vet Intern Med. 2018 Nov;32(6):1958-1964. doi: 10.1111/jvim.15301. Epub 2018 Oct 11.

6.

Clinical, morphological, and molecular characterization of an undetermined Babesia species in a maned wolf (Chrysocyon brachyurus).

Wasserkrug Naor A, Lindemann DM, Schreeg ME, Marr HS, Birkenheuer AJ, Carpenter JW, Ryseff JK.

Ticks Tick Borne Dis. 2019 Jan;10(1):124-126. doi: 10.1016/j.ttbdis.2018.09.005. Epub 2018 Sep 11.

PMID:
30245087
7.

Inhibition of ATR acutely sensitizes acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase.

Fordham SE, Blair HJ, Elstob CJ, Plummer R, Drew Y, Curtin NJ, Heidenreich O, Pal D, Jamieson D, Park C, Pollard J, Fields S, Milne P, Jackson GH, Marr HJ, Menne T, Jones GL, Allan JM.

Blood Adv. 2018 May 22;2(10):1157-1169. doi: 10.1182/bloodadvances.2017015214.

8.

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.

Sinclair PB, Blair HH, Ryan SL, Buechler L, Cheng J, Clayton J, Hanna R, Hollern S, Hawking Z, Bashton M, Schwab CJ, Jones L, Russell LJ, Marr H, Carey P, Halsey C, Heidenreich O, Moorman AV, Harrison CJ.

Haematologica. 2018 Apr;103(4):634-644. doi: 10.3324/haematol.2017.172304. Epub 2018 Feb 15.

9.

Endothelial alterations in a canine model of immune thrombocytopenia.

LeVine DN, Cianciolo RE, Linder KE, Bizikova P, Birkenheuer AJ, Brooks MB, Salous AK, Nordone SK, Bellinger DA, Marr H, Jones SL, Fischer TH, Deng Y, Mazepa M, Key NS.

Platelets. 2019;30(1):88-97. doi: 10.1080/09537104.2017.1378807. Epub 2017 Nov 28.

PMID:
29182425
10.

Molecular detection of vector-borne pathogens in Greek cats.

Mylonakis ME, Schreeg M, Chatzis MK, Pearce J, Marr HS, Saridomichelakis MN, Birkenheuer AJ.

Ticks Tick Borne Dis. 2018 Feb;9(2):171-175. doi: 10.1016/j.ttbdis.2017.08.013. Epub 2017 Sep 1.

PMID:
28887102
11.

Improved molecular detection of Babesia infections in animals using a novel quantitative real-time PCR diagnostic assay targeting mitochondrial DNA.

Qurollo BA, Archer NR, Schreeg ME, Marr HS, Birkenheuer AJ, Haney KN, Thomas BS, Breitschwerdt EB.

Parasit Vectors. 2017 Mar 7;10(1):128. doi: 10.1186/s13071-017-2064-1.

12.

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Law PJ, Berndt SI, Speedy HE, Camp NJ, Sava GP, Skibola CF, Holroyd A, Joseph V, Sunter NJ, Nieters A, Bea S, Monnereau A, Martin-Garcia D, Goldin LR, Clot G, Teras LR, Quintela I, Birmann BM, Jayne S, Cozen W, Majid A, Smedby KE, Lan Q, Dearden C, Brooks-Wilson AR, Hall AG, Purdue MP, Mainou-Fowler T, Vajdic CM, Jackson GH, Cocco P, Marr H, Zhang Y, Zheng T, Giles GG, Lawrence C, Call TG, Liebow M, Melbye M, Glimelius B, Mansouri L, Glenn M, Curtin K, Diver WR, Link BK, Conde L, Bracci PM, Holly EA, Jackson RD, Tinker LF, Benavente Y, Boffetta P, Brennan P, Maynadie M, McKay J, Albanes D, Weinstein S, Wang Z, Caporaso NE, Morton LM, Severson RK, Riboli E, Vineis P, Vermeulen RC, Southey MC, Milne RL, Clavel J, Topka S, Spinelli JJ, Kraft P, Ennas MG, Summerfield G, Ferri GM, Harris RJ, Miligi L, Pettitt AR, North KE, Allsup DJ, Fraumeni JF, Bailey JR, Offit K, Pratt G, Hjalgrim H, Pepper C, Chanock SJ, Fegan C, Rosenquist R, de Sanjose S, Carracedo A, Dyer MJ, Catovsky D, Campo E, Cerhan JR, Allan JM, Rothman N, Houlston R, Slager S.

Nat Commun. 2017 Feb 6;8:14175. doi: 10.1038/ncomms14175.

13.

Mitochondrial Genome Sequences and Structures Aid in the Resolution of Piroplasmida phylogeny.

Schreeg ME, Marr HS, Tarigo JL, Cohn LA, Bird DM, Scholl EH, Levy MG, Wiegmann BM, Birkenheuer AJ.

PLoS One. 2016 Nov 10;11(11):e0165702. doi: 10.1371/journal.pone.0165702. eCollection 2016.

14.

PCR amplification of a multi-copy mitochondrial gene (cox3) improves detection of Cytauxzoon felis infection as compared to a ribosomal gene (18S).

Schreeg ME, Marr HS, Griffith EH, Tarigo JL, Bird DM, Reichard MV, Cohn LA, Levy MG, Birkenheuer AJ.

Vet Parasitol. 2016 Jul 30;225:123-30. doi: 10.1016/j.vetpar.2016.06.013. Epub 2016 Jun 8.

PMID:
27369587
15.

Rapid High-Resolution Melt Analysis of Cytauxzoon felis Cytochrome b To Aid in the Prognosis of Cytauxzoonosis.

Schreeg ME, Marr HS, Tarigo JL, Cohn LA, Levy MG, Birkenheuer AJ.

J Clin Microbiol. 2015 Aug;53(8):2517-24. doi: 10.1128/JCM.00635-15. Epub 2015 May 27.

16.

Spironucleus meleagridis, an enteric diplomonad protozoan of cockatiels (Nymphicus hollandicus): preliminary molecular characterization and association with clinical disease.

Levy MG, Powers LV, Gore KC, Marr HS.

Vet Parasitol. 2015 Mar 15;208(3-4):169-73. doi: 10.1016/j.vetpar.2014.12.028. Epub 2015 Jan 3.

PMID:
25595477
17.

Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk.

Sava GP, Speedy HE, Di Bernardo MC, Dyer MJ, Holroyd A, Sunter NJ, Marr H, Mansouri L, Deaglio S, Karabon L, Frydecka I, Jamroziak K, Woszczyk D, Juliusson G, Smedby KE, Jayne S, Majid A, Wang Y, Dearden C, Hall AG, Mainou-Fowler T, Jackson GH, Summerfield G, Harris RJ, Pettitt AR, Allsup DJ, Bailey JR, Pratt G, Pepper C, Fegan C, Rosenquist R, Catovsky D, Allan JM, Houlston RS.

Leukemia. 2015 Mar;29(3):748-51. doi: 10.1038/leu.2014.311. Epub 2014 Nov 3. No abstract available.

18.

A novel canine model of immune thrombocytopenia: has immune thrombocytopenia (ITP) gone to the dogs?

LeVine DN, Birkenheuer AJ, Brooks MB, Nordone SK, Bellinger DA, Jones SL, Fischer TH, Oglesbee SE, Frey K, Brinson NS, Peters AP, Marr HS, Motsinger-Reif A, Gudbrandsdottir S, Bussel JB, Key NS.

Br J Haematol. 2014 Oct;167(1):110-20. doi: 10.1111/bjh.13005. Epub 2014 Jul 8.

19.

Investigation of a commercial ELISA for the detection of canine procalcitonin.

Floras AN, Holowaychuk MK, Hodgins DC, Marr HS, Birkenheuer A, Sharif S, Bersenas AM, Bienzle D.

J Vet Intern Med. 2014 Mar-Apr;28(2):599-602. doi: 10.1111/jvim.12309. Epub 2014 Feb 3.

20.

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges.

Lovci MT, Ghanem D, Marr H, Arnold J, Gee S, Parra M, Liang TY, Stark TJ, Gehman LT, Hoon S, Massirer KB, Pratt GA, Black DL, Gray JW, Conboy JG, Yeo GW.

Nat Struct Mol Biol. 2013 Dec;20(12):1434-42. doi: 10.1038/nsmb.2699. Epub 2013 Nov 10.

21.

Failure of efficacy and adverse events associated with dose-intense diminazene diaceturate treatment of chronic Cytauxzoon felis infection in five cats.

Lewis KM, Cohn LA, Marr HS, Birkenheuer AJ.

J Feline Med Surg. 2014 Feb;16(2):157-63. doi: 10.1177/1098612X13502974. Epub 2013 Sep 16.

PMID:
24043719
22.

Pharmacogenomics of Cytauxzoon felis cytochrome b: implications for atovaquone and azithromycin therapy in domestic cats with cytauxzoonosis.

Schreeg ME, Marr HS, Tarigo J, Cohn LA, Levy MG, Birkenheuer AJ.

J Clin Microbiol. 2013 Sep;51(9):3066-9. doi: 10.1128/JCM.01407-13. Epub 2013 Jun 19.

23.

Searching for clarity in therapy-related myelodysplastic syndrome/acute myeloid leukemia prognostication.

Fordham SE, Marr H, Allan JM.

Leuk Lymphoma. 2013 Mar;54(3):447-8. doi: 10.3109/10428194.2012.728289. Epub 2012 Sep 28. No abstract available.

PMID:
23020216
24.

Diminazene diaceturate for treatment of chronic Cytauxzoon felis parasitemia in naturally infected cats.

Lewis KM, Cohn LA, Marr HS, Birkenheuer AJ.

J Vet Intern Med. 2012 Nov-Dec;26(6):1490-3. doi: 10.1111/j.1939-1676.2012.01003.x. Epub 2012 Sep 24.

25.

Hypocalcemia and hypovitaminosis D in dogs with induced endotoxemia.

Holowaychuk MK, Birkenheuer AJ, Li J, Marr H, Boll A, Nordone SK.

J Vet Intern Med. 2012 Mar-Apr;26(2):244-51. doi: 10.1111/j.1939-1676.2012.00886.x. Epub 2012 Feb 28.

26.

Re-emergence of Babesia conradae and effective treatment of infected dogs with atovaquone and azithromycin.

Di Cicco MF, Downey ME, Beeler E, Marr H, Cyrog P, Kidd L, Diniz PP, Cohn LA, Birkenheuer AJ.

Vet Parasitol. 2012 Jun 8;187(1-2):23-7. doi: 10.1016/j.vetpar.2012.01.006. Epub 2012 Jan 8.

PMID:
22305297
27.

Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions.

Gallagher TL, Arribere JA, Geurts PA, Exner CR, McDonald KL, Dill KK, Marr HL, Adkar SS, Garnett AT, Amacher SL, Conboy JG.

Dev Biol. 2011 Nov 15;359(2):251-61. doi: 10.1016/j.ydbio.2011.08.025. Epub 2011 Sep 7.

28.

Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene.

Akwabi-Ameyaw A, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, Miller AB, Navas F 3rd, Parks DJ, Spearing PK, Todd D, Williams SP, Wisely GB.

Bioorg Med Chem Lett. 2011 Oct 15;21(20):6154-60. doi: 10.1016/j.bmcl.2011.08.034. Epub 2011 Aug 11.

PMID:
21890356
29.

Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils.

Li J, Birkenheuer AJ, Marr HS, Levy MG, Yoder JA, Nordone SK.

Dev Comp Immunol. 2011 Aug;35(8):872-80. doi: 10.1016/j.dci.2011.03.021. Epub 2011 Apr 28.

PMID:
21549750
30.

Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.

Bass JY, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, McFadyen RB, Miller AB, Mills WY, Navas F 3rd, Parks DJ, Smalley TL Jr, Spearing PK, Todd D, Williams SP, Wisely GB.

Bioorg Med Chem Lett. 2011 Feb 15;21(4):1206-13. doi: 10.1016/j.bmcl.2010.12.089. Epub 2010 Dec 23.

PMID:
21256005
31.

Prevalence of selected vector-borne organisms and identification of Bartonella species DNA in North American river otters (Lontra canadensis).

Chinnadurai SK, Birkenheuer AJ, Blanton HL, Maggi RG, Belfiore N, Marr HS, Breitschwerdt EB, Stoskopf MK.

J Wildl Dis. 2010 Jul;46(3):947-50.

PMID:
20688703
32.

Exon-level microarray analyses identify alternative splicing programs in breast cancer.

Lapuk A, Marr H, Jakkula L, Pedro H, Bhattacharya S, Purdom E, Hu Z, Simpson K, Pachter L, Durinck S, Wang N, Parvin B, Fontenay G, Speed T, Garbe J, Stampfer M, Bayandorian H, Dorton S, Clark TA, Schweitzer A, Wyrobek A, Feiler H, Spellman P, Conboy J, Gray JW.

Mol Cancer Res. 2010 Jul;8(7):961-74. doi: 10.1158/1541-7786.MCR-09-0528. Epub 2010 Jul 6.

33.

Babesia microti-like infections are prevalent in North American foxes.

Birkenheuer AJ, Horney B, Bailey M, Scott M, Sherbert B, Catto V, Marr HS, Camacho AT, Ballman AE.

Vet Parasitol. 2010 Sep 20;172(3-4):179-82. doi: 10.1016/j.vetpar.2010.05.020. Epub 2010 May 31.

PMID:
20580162
34.

Feasibility of administering zoledronic acid in palliative patients being cared for in the community: results of a pilot study.

Marr HK, Stiles CR, Boyar MA, Braun TC, Hagen NA, Janzen C, Whitten LM, Pereira JL.

Curr Oncol. 2010 Apr;17(2):69-74.

35.

Recruitment and retention of palliative cancer patients and their partners participating in a longitudinal evaluation of a psychosocial retreat program.

Garland SN, Carlson LE, Marr H, Simpson S.

Palliat Support Care. 2009 Mar;7(1):49-56. doi: 10.1017/S1478951509000078.

PMID:
19619374
36.

FXR agonist activity of conformationally constrained analogs of GW 4064.

Akwabi-Ameyaw A, Bass JY, Caldwell RD, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, McFadyen RB, Miller AB, Navas F 3rd, Parks DJ, Spearing PK, Todd D, Williams SP, Bruce Wisely G.

Bioorg Med Chem Lett. 2009 Aug 15;19(16):4733-9. doi: 10.1016/j.bmcl.2009.06.062. Epub 2009 Jun 21.

PMID:
19586769
37.

Successful treatment of transplant-associated microangiopathy with rituximab.

Marr H, McDonald EJ, Merriman E, Smith M, Mangos H, Stoddart C, Ganly P.

N Z Med J. 2009 Apr 3;122(1292):72-4.

PMID:
19448776
38.

Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064.

Bass JY, Caldwell RD, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, McFadyen RB, Miller AB, Parks DJ, Todd D, Williams SP, Wisely GB.

Bioorg Med Chem Lett. 2009 Jun 1;19(11):2969-73. doi: 10.1016/j.bmcl.2009.04.047. Epub 2009 Apr 18.

PMID:
19410460
39.

Not walking or communicating--is all well?

Ganly P, Saleem M, Marr H, Burt M, Florkowski C, Williamson A.

Lancet. 2008 Dec 13;372(9655):2086. doi: 10.1016/S0140-6736(08)61870-X. No abstract available.

PMID:
19070739
40.

Evaluation of four DNA extraction methods for the detection of Tritrichomonas foetus in feline stool specimens by polymerase chain reaction.

Stauffer SH, Birkenheuer AJ, Levy MG, Marr H, Gookin JL.

J Vet Diagn Invest. 2008 Sep;20(5):639-41.

PMID:
18776100
41.

Failure to identify an association between serologic or molecular evidence of Bartonella infection and idiopathic rhinitis in dogs.

Hawkins EC, Johnson LR, Guptill L, Marr HS, Breitschwerdt EB, Birkenheuer AJ.

J Am Vet Med Assoc. 2008 Aug 15;233(4):597-9. doi: 10.2460/javma.233.4.597.

PMID:
18710315
42.

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064.

Akwabi-Ameyaw A, Bass JY, Caldwell RD, Caravella JA, Chen L, Creech KL, Deaton DN, Jones SA, Kaldor I, Liu Y, Madauss KP, Marr HB, McFadyen RB, Miller AB, Navas F III, Parks DJ, Spearing PK, Todd D, Williams SP, Wisely GB.

Bioorg Med Chem Lett. 2008 Aug 1;18(15):4339-43. doi: 10.1016/j.bmcl.2008.06.073. Epub 2008 Jun 28.

PMID:
18621523
43.

Cytauxzoon felis infections are present in bobcats (Lynx rufus) in a region where cytauxzoonosis is not recognized in domestic cats.

Birkenheuer AJ, Marr HS, Warren C, Acton AE, Mucker EM, Humphreys JG, Tucker MD.

Vet Parasitol. 2008 May 6;153(1-2):126-30. doi: 10.1016/j.vetpar.2008.01.020. Epub 2008 Jan 19.

PMID:
18295403
44.

Bartonella DNA in the blood and lymph nodes of Golden Retrievers with lymphoma and in healthy controls.

Duncan AW, Marr HS, Birkenheuer AJ, Maggi RG, Williams LE, Correa MT, Breitschwerdt EB.

J Vet Intern Med. 2008 Jan-Feb;22(1):89-95. doi: 10.1111/j.1939-1676.2007.0018.x.

45.

Molecular evidence of prevalent dual piroplasma infections in North American raccoons (Procyon lotor).

Birkenheuer AJ, Marr HS, Hladio N, Acton AE.

Parasitology. 2008 Jan;135(Pt 1):33-7. Epub 2007 Sep 4.

PMID:
17767797
46.

A correlation with exon expression approach to identify cis-regulatory elements for tissue-specific alternative splicing.

Das D, Clark TA, Schweitzer A, Yamamoto M, Marr H, Arribere J, Minovitsky S, Poliakov A, Dubchak I, Blume JE, Conboy JG.

Nucleic Acids Res. 2007;35(14):4845-57. Epub 2007 Jul 10.

47.

Bartonella DNA in loggerhead sea turtles.

Valentine KH, Harms CA, Cadenas MB, Birkenheuer AJ, Marr HS, Braun-McNeill J, Maggi RG, Breitschwerdt EB.

Emerg Infect Dis. 2007 Jun;13(6):949-50. No abstract available.

48.

Quantification of mucin gene expression in tracheobronchial epithelium of healthy dogs and dogs with chronic bronchitis.

Hawkins EC, Birkenheuer AJ, Marr HS, Rogala AR, Large EE, Adler KB.

Am J Vet Res. 2007 Apr;68(4):435-40.

PMID:
17397301
49.

The detection of Cytauxzoon felis in apparently healthy free-roaming cats in the USA.

Haber MD, Tucker MD, Marr HS, Levy JK, Burgess J, Lappin MR, Birkenheuer AJ.

Vet Parasitol. 2007 May 31;146(3-4):316-20. Epub 2007 Mar 27.

PMID:
17391852
50.

The identification of a genetically unique piroplasma in North American river otters (Lontra canadensis).

Birkenheuer AJ, Harms CA, Neel J, Marr HS, Tucker MD, Acton AE, Tuttle AD, Stoskopf MK.

Parasitology. 2007 May;134(Pt 5):631-5. Epub 2007 Jan 11.

PMID:
17214914

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