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Understanding Determinants of Carbohydrate Metabolism and Their Contribution to Metabolic Health; The Impact of AMY1 CNV (P21-015-19).

O'Callaghan N, Valsesia A, Kulkarni S, Marquis J, Leone P, Mironova P, Walter O, Saris W, Descombes P, Hager J, Saris W, Astrup A, Darimont C.

Curr Dev Nutr. 2019 Jun 13;3(Suppl 1). pii: nzz041.P21-015-19. doi: 10.1093/cdn/nzz041.P21-015-19. eCollection 2019 Jun.


Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study.

Valsesia A, Kulkarni SS, Marquis J, Leone P, Mironova P, Walter O, Hjorth MF, Descombes P, Hager J, Saris WH, Astrup A, Darimont C, O'Callaghan NJ.

Am J Clin Nutr. 2019 Apr 1;109(4):1029-1037. doi: 10.1093/ajcn/nqy363.


Genetic Risk Score Predictive of the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation in a Mexican Population.

Vallée Marcotte B, Guénard F, Marquis J, Charpagne A, Vadillo-Ortega F, Tejero ME, Binia A, Vohl MC.

Nutrients. 2019 Mar 29;11(4). pii: E737. doi: 10.3390/nu11040737.


Development of a Long-Wave Infrared Band-Edge (LWIR BE) thermometry instrument.

Marquis J, Roodenko K, Pinsukanjana P, Frensley W.

Rev Sci Instrum. 2018 Jul;89(7):074903. doi: 10.1063/1.5002109.


Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs.

Yeung J, Mermet J, Jouffe C, Marquis J, Charpagne A, Gachon F, Naef F.

Genome Res. 2018 Feb;28(2):182-191. doi: 10.1101/gr.222430.117. Epub 2017 Dec 18.


One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond.

Dayon L, Guiraud SP, Corthésy J, Da Silva L, Migliavacca E, Tautvydaitė D, Oikonomidi A, Moullet B, Henry H, Métairon S, Marquis J, Descombes P, Collino S, Martin FJ, Montoliu I, Kussmann M, Wojcik J, Bowman GL, Popp J.

Alzheimers Res Ther. 2017 Jun 17;9(1):43. doi: 10.1186/s13195-017-0270-x.


Left Atrial Dissection After Percutaneous Transluminal Mitral Valvuloplasty.

Di Santo P, Simard T, Marquis JF, Hibbert B.

Can J Cardiol. 2017 Jun;33(6):831.e5-831.e6. doi: 10.1016/j.cjca.2017.02.012. Epub 2017 Mar 2. No abstract available.


MitoRS, a method for high throughput, sensitive, and accurate detection of mitochondrial DNA heteroplasmy.

Marquis J, Lefebvre G, Kourmpetis YAI, Kassam M, Ronga F, De Marchi U, Wiederkehr A, Descombes P.

BMC Genomics. 2017 Apr 26;18(1):326. doi: 10.1186/s12864-017-3695-5.


Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases.

Giuliani C, Pirazzini C, Delledonne M, Xumerle L, Descombes P, Marquis J, Mengozzi G, Monti D, Bellizzi D, Passarino G, Luiselli D, Franceschi C, Garagnani P.

Mech Ageing Dev. 2017 Jul;165(Pt B):195-201. doi: 10.1016/j.mad.2017.02.007. Epub 2017 Feb 27. Review.


Early Canadian Multicenter Experience With WATCHMAN for Percutaneous Left Atrial Appendage Closure.

Saw J, Fahmy P, Azzalini L, Marquis JF, Hibbert B, Morillo C, Carrizo A, Ibrahim R.

J Cardiovasc Electrophysiol. 2017 Apr;28(4):396-401. doi: 10.1111/jce.13168. Epub 2017 Mar 6.


Impact of mean arterial pressure on clinical outcomes in comatose survivors of out-of-hospital cardiac arrest: Insights from the University of Ottawa Heart Institute Regional Cardiac Arrest Registry (CAPITAL-CARe).

Russo JJ, James TE, Hibbert B, Yousef A, Osborne C, Wells GA, Froeschl MP, So DY, Chong AY, Labinaz M, Glover CA, Marquis JF, Dick A, Bernick J, Le May MR.

Resuscitation. 2017 Apr;113:27-32. doi: 10.1016/j.resuscitation.2017.01.007. Epub 2017 Jan 18.


Commitment and capacity for providing evidence-based tobacco treatment in US drug treatment facilities.

Richter KP, Hunt JJ, Cupertino AP, Gajewski BJ, Jiang Y, Marquis J, Friedmann PD.

Subst Abus. 2017 Jan-Mar;38(1):35-39. doi: 10.1080/08897077.2016.1265039. Epub 2016 Nov 29.


A randomised study for optimising crossover from ticagrelor to clopidogrel in patients with acute coronary syndrome. The CAPITAL OPTI-CROSS Study.

Pourdjabbar A, Hibbert B, Chong AY, Le May MR, Labinaz M, Simard T, Ramirez FD, Lugomirski P, Maze R, Froeschl M, Glover C, Dick A, Marquis JF, Bernick J, Wells G, So DY; CAPITAL Investigators.

Thromb Haemost. 2017 Jan 26;117(2):303-310. doi: 10.1160/TH16-04-0340. Epub 2016 Oct 20.


Safety and Efficacy of a Pharmacoinvasive Strategy in ST-Segment Elevation Myocardial Infarction: A Patient Population Study Comparing a Pharmacoinvasive Strategy With a Primary Percutaneous Coronary Intervention Strategy Within a Regional System.

Rashid MK, Guron N, Bernick J, Wells GA, Blondeau M, Chong AY, Dick A, Froeschl MP, Glover CA, Hibbert B, Labinaz M, Marquis JF, Osborne C, So DY, Le May MR.

JACC Cardiovasc Interv. 2016 Oct 10;9(19):2014-2020. doi: 10.1016/j.jcin.2016.07.004.


Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B.

Korolowicz KE, Iyer RP, Czerwinski S, Suresh M, Yang J, Padmanabhan S, Sheri A, Pandey RK, Skell J, Marquis JK, Kallakury BV, Tucker RD, Menne S.

PLoS One. 2016 Aug 23;11(8):e0161313. doi: 10.1371/journal.pone.0161313. eCollection 2016.


Effects of Morphine on Behavioral Task Performance in SIV-Infected Rhesus Macaques.

Marcario JK, Pendyala G, Riazi M, Fleming K, Marquis J, Callen S, Lisco SJ, Fowler SC, Cheney PD, Buch SJ.

J Neuroimmune Pharmacol. 2016 Jun;11(2):348-57. doi: 10.1007/s11481-016-9667-8. Epub 2016 Apr 2.


Ticagrelor in Triple Antithrombotic Therapy: Predictors of Ischemic and Bleeding Complications.

Fu A, Singh K, Abunassar J, Malhotra N, Le May M, Labinaz M, Glover C, Marquis JF, Froeschl M, Dick A, Hibbert B, Chong AY, So DY; CAPITAL Investigators.

Clin Cardiol. 2016 Jan;39(1):19-23. doi: 10.1002/clc.22486. Epub 2016 Jan 8.


Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver.

Atger F, Gobet C, Marquis J, Martin E, Wang J, Weger B, Lefebvre G, Descombes P, Naef F, Gachon F.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6579-88. doi: 10.1073/pnas.1515308112. Epub 2015 Nov 9.


Safety and Efficacy of Staged Percutaneous Coronary Intervention During Index Admission for ST-Elevation Myocardial Infarction With Multivessel Coronary Disease (Insights from the University of Ottawa Heart Institute STEMI Registry).

Russo JJ, Wells GA, Chong AY, So DY, Glover CA, Froeschl MP, Hibbert B, Marquis JF, Dick A, Blondeau M, Bernick J, Labinaz M, Le May MR; CAPITAL Investigators.

Am J Cardiol. 2015 Oct 15;116(8):1157-62. doi: 10.1016/j.amjcard.2015.07.029. Epub 2015 Jul 29.


A pharmacodynamic comparison of a personalized strategy for anti-platelet therapy versus ticagrelor in achieving a therapeutic window.

Malhotra N, Abunassar J, Wells GA, McPherson R, Fu A, Hibbert B, Labinaz M, Le May M, Dick A, Glover C, Froeschl M, Marquis JF, Tran L, Bernick J, Chong AY, So DY; CArdiovascular Percutaneous Intervention TriAL (CAPITAL) investigators.

Int J Cardiol. 2015 Oct 15;197:318-25. doi: 10.1016/j.ijcard.2015.06.016. Epub 2015 Jun 15.


The Use of Non-Variant Sites to Improve the Clinical Assessment of Whole-Genome Sequence Data.

Ferrarini A, Xumerle L, Griggio F, Garonzi M, Cantaloni C, Centomo C, Vargas SM, Descombes P, Marquis J, Collino S, Franceschi C, Garagnani P, Salisbury BA, Harvey JM, Delledonne M.

PLoS One. 2015 Jul 6;10(7):e0132180. doi: 10.1371/journal.pone.0132180. eCollection 2015.


A prospective randomized evaluation of a pharmacogenomic approach to antiplatelet therapy among patients with ST-elevation myocardial infarction: the RAPID STEMI study.

So DY, Wells GA, McPherson R, Labinaz M, Le May MR, Glover C, Dick AJ, Froeschl M, Marquis JF, Gollob MH, Tran L, Bernick J, Hibbert B, Roberts JD.

Pharmacogenomics J. 2016 Feb;16(1):71-8. doi: 10.1038/tpj.2015.17. Epub 2015 Apr 7.


Prophylactic warfarin therapy after primary percutaneous coronary intervention for anterior ST-segment elevation myocardial infarction.

Le May MR, Acharya S, Wells GA, Burwash I, Chong AY, So DY, Glover CA, Froeschl MPV, Hibbert B, Marquis JF, Dick A, Blondeau M, Bernick J, Labinaz M.

JACC Cardiovasc Interv. 2015 Jan;8(1 Pt B):155-162. doi: 10.1016/j.jcin.2014.07.018. Epub 2014 Oct 30.


Exploring the implementation of a medication adherence programme by community pharmacists: a qualitative study.

Marquis J, Schneider MP, Spencer B, Bugnon O, Du Pasquier S.

Int J Clin Pharm. 2014 Oct;36(5):1014-22. doi: 10.1007/s11096-014-9989-7. Epub 2014 Aug 20.


Risk factors for self-injury, aggression, and stereotyped behavior among young children at risk for intellectual and developmental disabilities.

Schroeder SR, Marquis JG, Reese RM, Richman DM, Mayo-Ortega L, Oyama-Ganiko R, LeBlanc J, Brady N, Butler MG, Johnson T, Lawrence L.

Am J Intellect Dev Disabil. 2014 Jul;119(4):351-70. doi: 10.1352/1944-7558-119.4.351.


Granulocyte colony-stimulating factor therapy for stem cell mobilization following anterior wall myocardial infarction: the CAPITAL STEM MI randomized trial.

Hibbert B, Hayley B, Beanlands RS, Le May M, Davies R, So D, Marquis JF, Labinaz M, Froeschl M, O'Brien ER, Burwash IG, Wells GA, Pourdjabbar A, Simard T, Atkins H, Glover C.

CMAJ. 2014 Aug 5;186(11):E427-34. doi: 10.1503/cmaj.140133. Epub 2014 Jun 16.


A comparative pharmacodynamic study of ticagrelor versus clopidogrel and ticagrelor in patients undergoing primary percutaneous coronary intervention: the CAPITAL RELOAD study.

Hibbert B, Maze R, Pourdjabbar A, Simard T, Ramirez FD, Moudgil R, Blondeau M, Labinaz M, Dick A, Glover C, Froeschl M, Marquis JF, So DY, Le May MR.

PLoS One. 2014 Mar 20;9(3):e92078. doi: 10.1371/journal.pone.0092078. eCollection 2014.


[A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy].

Barde I, Rauwel B, Marin-Florez RM, Corsinotti A, Laurenti E, Verp S, Offner S, Marquis J, Kapopoulou A, Vanicek J, Trono D.

Med Sci (Paris). 2014 Jan;30(1):12-5. doi: 10.1051/medsci/20143001003. Epub 2014 Jan 24. French. No abstract available.


Swallowing difficulties with oral drugs among polypharmacy patients attending community pharmacies.

Marquis J, Schneider MP, Payot V, Cordonier AC, Bugnon O, Hersberger KE, Arnet I.

Int J Clin Pharm. 2013 Dec;35(6):1130-6. doi: 10.1007/s11096-013-9836-2. Epub 2013 Aug 21.


99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer.

Hillier SM, Maresca KP, Lu G, Merkin RD, Marquis JC, Zimmerman CN, Eckelman WC, Joyal JL, Babich JW.

J Nucl Med. 2013 Aug;54(8):1369-76. doi: 10.2967/jnumed.112.116624. Epub 2013 Jun 3.


Percutaneous left atrial appendage closure with the AMPLATZER cardiac plug device in patients with nonvalvular atrial fibrillation and contraindications to anticoagulation therapy.

Urena M, Rodés-Cabau J, Freixa X, Saw J, Webb JG, Freeman M, Horlick E, Osten M, Chan A, Marquis JF, Champagne J, Ibrahim R.

J Am Coll Cardiol. 2013 Jul 9;62(2):96-102. doi: 10.1016/j.jacc.2013.02.089. Epub 2013 May 9.


Response to letter regarding article, "Bivalirudin for primary percutaneous coronary interventions: outcome assessment in the Ottawa STEMI registry".

Hibbert B, MacDougall A, Blondeau M, O'Brien ER, So DY, Labinaz M, Dick A, Glover C, Froeschl M, Marquis JF, Wells GA, Le May MR.

Circ Cardiovasc Interv. 2013 Apr;6(2):e27. doi: 10.1161/CIRCINTERVENTIONS.113.000133. No abstract available.


Validity and reliability of the Behavior Problems Inventory, the Aberrant Behavior Checklist, and the Repetitive Behavior Scale-Revised among infants and toddlers at risk for intellectual or developmental disabilities: a multi-method assessment approach.

Rojahn J, Schroeder SR, Mayo-Ortega L, Oyama-Ganiko R, LeBlanc J, Marquis J, Berke E.

Res Dev Disabil. 2013 May;34(5):1804-14. doi: 10.1016/j.ridd.2013.02.024. Epub 2013 Mar 16.


The index of tobacco treatment quality: development of a tool to assess evidence-based treatment in a national sample of drug treatment facilities.

Cupertino AP, Hunt JJ, Gajewski BJ, Jiang Y, Marquis J, Friedmann PD, Engelman KK, Richter KP.

Subst Abuse Treat Prev Policy. 2013 Mar 15;8:13. doi: 10.1186/1747-597X-8-13.


A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy.

Barde I, Rauwel B, Marin-Florez RM, Corsinotti A, Laurenti E, Verp S, Offner S, Marquis J, Kapopoulou A, Vanicek J, Trono D.

Science. 2013 Apr 19;340(6130):350-3. doi: 10.1126/science.1232398. Epub 2013 Mar 14.


Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression.

Márquez C, Poirier GL, Cordero MI, Larsen MH, Groner A, Marquis J, Magistretti PJ, Trono D, Sandi C.

Transl Psychiatry. 2013 Jan 15;3:e216. doi: 10.1038/tp.2012.144.


De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET.

Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D.

Development. 2013 Feb 1;140(3):519-29. doi: 10.1242/dev.087585.


Bivalirudin for primary percutaneous coronary interventions: outcome assessment in the Ottawa STEMI registry.

Hibbert B, MacDougall A, Labinaz M, O'Brien ER, So DY, Dick A, Glover C, Froeschl M, Marquis JF, Wells GA, Blondeau M, Le May MR.

Circ Cardiovasc Interv. 2012 Dec;5(6):805-12. doi: 10.1161/CIRCINTERVENTIONS.112.968966. Epub 2012 Nov 13.


Reduction in mortality as a result of direct transport from the field to a receiving center for primary percutaneous coronary intervention.

Le May MR, Wells GA, So DY, Glover CA, Froeschl M, Maloney J, Dionne R, Marquis JF, O'Brien ER, Dick A, Sherrard HL, Trickett J, Poirier P, Blondeau M, Bernick J, Labinaz M.

J Am Coll Cardiol. 2012 Oct 2;60(14):1223-30. doi: 10.1016/j.jacc.2012.07.008.


Mass Screening for Severe Problem Behavior among Infants and Toddlers In Peru.

Mayo-Ortega L, Oyama-Ganiko R, Leblanc J, Schroeder SR, Brady N, Butler MG, Reese RM, Richman DM, Peacock G, Foster J, Marquis J.

J Ment Health Res Intellect Disabil. 2012 Jan 1;5(3-4):246-259. Epub 2012 Jul 2.


The impact of therapeutic hypothermia as adjunctive therapy in a regional primary PCI program.

Maze R, Le May MR, Hibbert B, So DY, Froeschl M, Glover CA, Dick A, Marquis JF, Blondeau M, Labinaz M.

Resuscitation. 2013 Apr;84(4):460-4. doi: 10.1016/j.resuscitation.2012.08.002. Epub 2012 Aug 21.


Transradial versus transfemoral artery approach for coronary angiography and percutaneous coronary intervention in the extremely obese.

Hibbert B, Simard T, Wilson KR, Hawken S, Wells GA, Ramirez FD, Le May MR, So DY, Glover CA, Froeschl M, Marquis JF, Labinaz M, Dick A, O'Brien ER.

JACC Cardiovasc Interv. 2012 Aug;5(8):819-26. doi: 10.1016/j.jcin.2012.04.009.


Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial.

Roberts JD, Wells GA, Le May MR, Labinaz M, Glover C, Froeschl M, Dick A, Marquis JF, O'Brien E, Goncalves S, Druce I, Stewart A, Gollob MH, So DY.

Lancet. 2012 May 5;379(9827):1705-11. doi: 10.1016/S0140-6736(12)60161-5. Epub 2012 Mar 29.


Resistance training volume, energy balance and weight management: rationale and design of a 9 month trial.

Washburn RA, Donnelly JE, Smith BK, Sullivan DK, Marquis J, Herrmann SD.

Contemp Clin Trials. 2012 Jul;33(4):749-58. doi: 10.1016/j.cct.2012.03.002. Epub 2012 Mar 13.


Metabolism, pharmacokinetics, tissue distribution, and stability studies of the prodrug analog of an anti-hepatitis B virus dinucleoside phosphorothioate.

Coughlin JE, Pandey RK, Padmanabhan S, O'Loughlin KG, Marquis J, Green CE, Mirsalis JC, Iyer RP.

Drug Metab Dispos. 2012 May;40(5):970-81. doi: 10.1124/dmd.111.044446. Epub 2012 Feb 10.


Development of the communication complexity scale.

Brady NC, Fleming K, Thiemann-Bourque K, Olswang L, Dowden P, Saunders MD, Marquis J.

Am J Speech Lang Pathol. 2012 Feb;21(1):16-28. doi: 10.1044/1058-0360(2011/10-0099). Epub 2011 Nov 2.


Unprotected left main coronary artery stenting with zotarolimus (Endeavor) drug-eluting stents: a single center retrospective experience.

Simard T, Hibbert B, Chong AY, Ruchin P, Le May M, Labinaz M, Froeschl M, So D, Glover C, Marquis JF, O'Brien E.

Catheter Cardiovasc Interv. 2012 Aug 1;80(2):E15-22. doi: 10.1002/ccd.23244. Epub 2012 Jan 10.


Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis.

Marquis JF, Kapoustina O, Langlais D, Ruddy R, Dufour CR, Kim BH, MacMicking JD, Giguère V, Gros P.

PLoS Genet. 2011 Jun;7(6):e1002097. doi: 10.1371/journal.pgen.1002097. Epub 2011 Jun 23.


123I-MIP-1072, a small-molecule inhibitor of prostate-specific membrane antigen, is effective at monitoring tumor response to taxane therapy.

Hillier SM, Kern AM, Maresca KP, Marquis JC, Eckelman WC, Joyal JL, Babich JW.

J Nucl Med. 2011 Jul;52(7):1087-93. doi: 10.2967/jnumed.110.086751. Epub 2011 Jun 16.


Usefulness of mean platelet volume as a biomarker for long-term outcomes after percutaneous coronary intervention.

Goncalves SC, Labinaz M, Le May M, Glover C, Froeschl M, Marquis JF, O'Brien E, Shukla D, Ruchin P, Sookur D, Ha A, So D.

Am J Cardiol. 2011 Jan 15;107(2):204-9. doi: 10.1016/j.amjcard.2010.08.068. Epub 2010 Dec 2.


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