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Items: 4


Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport.

Magiera MM, Bodakuntla S, Žiak J, Lacomme S, Marques Sousa P, Leboucher S, Hausrat TJ, Bosc C, Andrieux A, Kneussel M, Landry M, Calas A, Balastik M, Janke C.

EMBO J. 2018 Dec 3;37(23). pii: e100440. doi: 10.15252/embj.2018100440. Epub 2018 Nov 12.


Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration.

Bosch Grau M, Masson C, Gadadhar S, Rocha C, Tort O, Marques Sousa P, Vacher S, Bieche I, Janke C.

J Cell Sci. 2017 Mar 1;130(5):938-949. doi: 10.1242/jcs.199091. Epub 2017 Jan 19.


Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.

Rocha C, Papon L, Cacheux W, Marques Sousa P, Lascano V, Tort O, Giordano T, Vacher S, Lemmers B, Mariani P, Meseure D, Medema JP, Bièche I, Hahne M, Janke C.

EMBO J. 2014 Oct 1;33(19):2247-60. doi: 10.15252/embj.201488466. Epub 2014 Sep 1. Erratum in: EMBO J. 2014 Nov 18;33(22):2735.


Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia.

Bosch Grau M, Gonzalez Curto G, Rocha C, Magiera MM, Marques Sousa P, Giordano T, Spassky N, Janke C.

J Cell Biol. 2013 Aug 5;202(3):441-51. doi: 10.1083/jcb.201305041. Epub 2013 Jul 29.

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