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Anaplastic Thyroid Cancer Cells Induce the Release of Mitochondrial Extracellular DNA Traps by Viable Neutrophils.

Cristinziano L, Modestino L, Loffredo S, Varricchi G, Braile M, Ferrara AL, de Paulis A, Antonelli A, Marone G, Galdiero MR.

J Immunol. 2020 Jan 20. pii: ji1900543. doi: 10.4049/jimmunol.1900543. [Epub ahead of print]


Mast Cells: Fascinating but Still Elusive after 140 Years from Their Discovery.

Varricchi G, Marone G.

Int J Mol Sci. 2020 Jan 11;21(2). pii: E464. doi: 10.3390/ijms21020464.


The Intriguing Role of Interleukin 13 in the Pathophysiology of Asthma.

Marone G, Granata F, Pucino V, Pecoraro A, Heffler E, Loffredo S, Scadding GW, Varricchi G.

Front Pharmacol. 2019 Dec 6;10:1387. doi: 10.3389/fphar.2019.01387. eCollection 2019. Review.


Hereditary angioedema attack: what happens to vasoactive mediators?

Ferrara AL, Bova M, Petraroli A, Veszeli N, Galdiero MR, Braile M, Marone G, Cristinziano L, Marcella S, Modestino L, Farkas H, Loffredo S.

Int Immunopharmacol. 2020 Jan;78:106079. doi: 10.1016/j.intimp.2019.106079. Epub 2019 Dec 13.


Lactate: Fueling the fire starter.

Certo M, Marone G, de Paulis A, Mauro C, Pucino V.

Wiley Interdiscip Rev Syst Biol Med. 2019 Dec 16:e1474. doi: 10.1002/wsbm.1474. [Epub ahead of print] Review.


Tezepelumab: a novel biological therapy for the treatment of severe uncontrolled asthma.

Marone G, Spadaro G, Braile M, Poto R, Criscuolo G, Pahima H, Loffredo S, Levi-Schaffer F, Varricchi G.

Expert Opin Investig Drugs. 2019 Nov;28(11):931-940. doi: 10.1080/13543784.2019.1672657. Epub 2019 Oct 10. Review.


Immune and Inflammatory Cells in Thyroid Cancer Microenvironment.

Ferrari SM, Fallahi P, Galdiero MR, Ruffilli I, Elia G, Ragusa F, Paparo SR, Patrizio A, Mazzi V, Varricchi G, Marone G, Antonelli A.

Int J Mol Sci. 2019 Sep 7;20(18). pii: E4413. doi: 10.3390/ijms20184413. Review.


Future Needs in Mast Cell Biology.

Varricchi G, de Paulis A, Marone G, Galli SJ.

Int J Mol Sci. 2019 Sep 6;20(18). pii: E4397. doi: 10.3390/ijms20184397. Review.


What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients?

Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG.

Antioxid Redox Signal. 2019 Nov 20;31(15):1166-1174. doi: 10.1089/ars.2019.7842. Epub 2019 Sep 23.


The Immune Landscape of Thyroid Cancer in the Context of Immune Checkpoint Inhibition.

Varricchi G, Loffredo S, Marone G, Modestino L, Fallahi P, Ferrari SM, de Paulis A, Antonelli A, Galdiero MR.

Int J Mol Sci. 2019 Aug 13;20(16). pii: E3934. doi: 10.3390/ijms20163934. Review.


Basophil degranulation in response to IgE ligation is controlled by a distinctive circadian clock in asthma.

Spadaro G, Giurato G, Stellato C, Marone G, Casolaro V.

Allergy. 2020 Jan;75(1):158-168. doi: 10.1111/all.14002. Epub 2019 Oct 23.


Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis.

Ferrara AL, Piscitelli F, Petraroli A, Parente R, Galdiero MR, Varricchi G, Marone G, Triggiani M, Di Marzo V, Loffredo S.

J Immunol Res. 2019 Jul 1;2019:5836476. doi: 10.1155/2019/5836476. eCollection 2019.


Heterogeneity of Human Mast Cells With Respect to MRGPRX2 Receptor Expression and Function.

Varricchi G, Pecoraro A, Loffredo S, Poto R, Rivellese F, Genovese A, Marone G, Spadaro G.

Front Cell Neurosci. 2019 Jul 3;13:299. doi: 10.3389/fncel.2019.00299. eCollection 2019.


Autoimmune Endocrine Dysfunctions Associated with Cancer Immunotherapies.

Ferrari SM, Fallahi P, Elia G, Ragusa F, Ruffilli I, Patrizio A, Galdiero MR, Baldini E, Ulisse S, Marone G, Antonelli A.

Int J Mol Sci. 2019 May 24;20(10). pii: E2560. doi: 10.3390/ijms20102560. Review.


Physiological Roles of Mast Cells: Collegium Internationale Allergologicum Update 2019.

Varricchi G, Rossi FW, Galdiero MR, Granata F, Criscuolo G, Spadaro G, de Paulis A, Marone G.

Int Arch Allergy Immunol. 2019;179(4):247-261. doi: 10.1159/000500088. Epub 2019 May 28. Review.


Immunosuppressive therapy with rituximab in common variable immunodeficiency.

Pecoraro A, Crescenzi L, Galdiero MR, Marone G, Rivellese F, Rossi FW, de Paulis A, Genovese A, Spadaro G.

Clin Mol Allergy. 2019 May 6;17:9. doi: 10.1186/s12948-019-0113-3. eCollection 2019. Review.


Mast Cells, Angiogenesis and Lymphangiogenesis in Human Gastric Cancer.

Sammarco G, Varricchi G, Ferraro V, Ammendola M, De Fazio M, Altomare DF, Luposella M, Maltese L, Curr├▓ G, Marone G, Ranieri G, Memeo R.

Int J Mol Sci. 2019 Apr 29;20(9). pii: E2106. doi: 10.3390/ijms20092106. Review.


Superantigenic Activation of Human Cardiac Mast Cells.

Varricchi G, Loffredo S, Borriello F, Pecoraro A, Rivellese F, Genovese A, Spadaro G, Marone G.

Int J Mol Sci. 2019 Apr 12;20(8). pii: E1828. doi: 10.3390/ijms20081828.


Innate Immune Modulation by GM-CSF and IL-3 in Health and Disease.

Borriello F, Galdiero MR, Varricchi G, Loffredo S, Spadaro G, Marone G.

Int J Mol Sci. 2019 Feb 15;20(4). pii: E834. doi: 10.3390/ijms20040834. Review.


Prostaglandin D2 receptor antagonists in allergic disorders: safety, efficacy, and future perspectives.

Marone G, Galdiero MR, Pecoraro A, Pucino V, Criscuolo G, Triassi M, Varricchi G.

Expert Opin Investig Drugs. 2019 Jan;28(1):73-84. doi: 10.1080/13543784.2019.1555237. Epub 2018 Dec 7. Review.


The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity.

Afferni C, Buccione C, Andreone S, Galdiero MR, Varricchi G, Marone G, Mattei F, Schiavoni G.

Front Immunol. 2018 Nov 13;9:2601. doi: 10.3389/fimmu.2018.02601. eCollection 2018. Review.


Nasal allergen-neutralizing IgG4 antibodies block IgE-mediated responses: Novel biomarker of subcutaneous grass pollen immunotherapy.

Shamji MH, Kappen J, Abubakar-Waziri H, Zhang J, Steveling E, Watchman S, Kouser L, Eifan A, Switzer A, Varricchi G, Marone G, Couto-Francisco NC, Calderon M, Durham SR.

J Allergy Clin Immunol. 2019 Mar;143(3):1067-1076. doi: 10.1016/j.jaci.2018.09.039. Epub 2018 Nov 14.


Pharmacovigilating cardiotoxicity of immune checkpoint inhibitors.

Varricchi G, Galdiero MR, Mercurio V, Bonaduce D, Marone G, Tocchetti CG.

Lancet Oncol. 2018 Dec;19(12):1545-1546. doi: 10.1016/S1470-2045(18)30622-3. Epub 2018 Nov 12. No abstract available.


Gastroduodenal Disorders in Patients with CVID Undergoing Immunoglobulin Therapy.

Varricchi G, Pecoraro A, Crescenzi L, Marone G, Travaglino A, D'Armiento FP, Genovese A, Spadaro G.

Curr Pharm Biotechnol. 2018;19(9):734-741. doi: 10.2174/1389201019666181010170630.


Hereditary angioedema: the plasma contact system out of control: comment.

Loffredo S, Marone G.

J Thromb Haemost. 2018 Nov;16(11):2347-2348. doi: 10.1111/jth.14270. Epub 2018 Sep 14. No abstract available.


Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production.

Rivellese F, Mauro D, Nerviani A, Pagani S, Fossati-Jimack L, Messemaker T, Kurreeman FAS, Toes REM, Ramming A, Rauber S, Schett G, Jones GW, Jones SA, Rossi FW, de Paulis A, Marone G, El Shikh MEM, Humby F, Pitzalis C.

Ann Rheum Dis. 2018 Dec;77(12):1773-1781. doi: 10.1136/annrheumdis-2018-213418. Epub 2018 Aug 20.


Validation of Calculated Globulin (CG) as a Screening Test for Antibody Deficiency in an Italian University Hospital.

Pecoraro A, Jolles S, Crescenzi L, Varricchi G, Marone G, Savoia M, Genovese A, Spadaro G.

Curr Pharm Biotechnol. 2018;19(9):728-733. doi: 10.2174/1389201019666180808163311.


Secreted Phospholipases A2 in Hereditary Angioedema With C1-Inhibitor Deficiency.

Loffredo S, Ferrara AL, Bova M, Borriello F, Suffritti C, Veszeli N, Petraroli A, Galdiero MR, Varricchi G, Granata F, Zanichelli A, Farkas H, Cicardi M, Lambeau G, Marone G.

Front Immunol. 2018 Jul 23;9:1721. doi: 10.3389/fimmu.2018.01721. eCollection 2018.


Thymic Stromal Lymphopoietin Isoforms, Inflammatory Disorders, and Cancer.

Varricchi G, Pecoraro A, Marone G, Criscuolo G, Spadaro G, Genovese A, Marone G.

Front Immunol. 2018 Jul 13;9:1595. doi: 10.3389/fimmu.2018.01595. eCollection 2018. Review.


Emotional processes and stress in children affected by hereditary angioedema with C1-inhibitor deficiency: a multicenter, prospective study.

Savarese L, Bova M, De Falco R, Guarino MD, De Luca Picione R, Petraroli A, Senter R, Traverso C, Zabotto M, Zanichelli A, Zito E, Alessio M, Cancian M, Cicardi M, Franzese A, Perricone R, Marone G, Valerio P, Freda MF.

Orphanet J Rare Dis. 2018 Jul 13;13(1):115. doi: 10.1186/s13023-018-0871-x.


Potential involvement of neutrophils in human thyroid cancer.

Galdiero MR, Varricchi G, Loffredo S, Bellevicine C, Lansione T, Ferrara AL, Iannone R, di Somma S, Borriello F, Clery E, Triassi M, Troncone G, Marone G.

PLoS One. 2018 Jun 28;13(6):e0199740. doi: 10.1371/journal.pone.0199740. eCollection 2018.


Innate effector cells in angiogenesis and lymphangiogenesis.

Varricchi G, Loffredo S, Galdiero MR, Marone G, Cristinziano L, Granata F, Marone G.

Curr Opin Immunol. 2018 Aug;53:152-160. doi: 10.1016/j.coi.2018.05.002. Epub 2018 May 17. Review.


N-Formyl Peptide Receptors Induce Radical Oxygen Production in Fibroblasts Derived From Systemic Sclerosis by Interacting With a Cleaved Form of Urokinase Receptor.

Napolitano F, Rossi FW, Pesapane A, Varricchio S, Ilardi G, Mascolo M, Staibano S, Lavecchia A, Ragno P, Selleri C, Marone G, Matucci-Cerinic M, de Paulis A, Montuori N.

Front Immunol. 2018 Apr 4;9:574. doi: 10.3389/fimmu.2018.00574. eCollection 2018.


Antineoplastic Drug-Induced Cardiotoxicity: A Redox Perspective.

Varricchi G, Ameri P, Cadeddu C, Ghigo A, Madonna R, Marone G, Mercurio V, Monte I, Novo G, Parrella P, Pirozzi F, Pecoraro A, Spallarossa P, Zito C, Mercuro G, Pagliaro P, Tocchetti CG.

Front Physiol. 2018 Mar 7;9:167. doi: 10.3389/fphys.2018.00167. eCollection 2018. Review.


Human mast cells and basophils-How are they similar how are they different?

Varricchi G, Raap U, Rivellese F, Marone G, Gibbs BF.

Immunol Rev. 2018 Mar;282(1):8-34. doi: 10.1111/imr.12627. Review.


Roles of neutrophils in cancer growth and progression.

Galdiero MR, Varricchi G, Loffredo S, Mantovani A, Marone G.

J Leukoc Biol. 2018 Mar;103(3):457-464. doi: 10.1002/JLB.3MR0717-292R. Epub 2017 Dec 15. Review.


Novel Biological Therapies in Severe Asthma: Targeting the Right Trait.

Varricchi G, Marone G, Spadaro G, Russo M, Granata F, Genovese A, Marone G.

Curr Med Chem. 2019;26(16):2801-2822. doi: 10.2174/0929867325666180110094542. Review.


Eosinophils: The unsung heroes in cancer?

Varricchi G, Galdiero MR, Loffredo S, Lucarini V, Marone G, Mattei F, Marone G, Schiavoni G.

Oncoimmunology. 2017 Nov 13;7(2):e1393134. doi: 10.1080/2162402X.2017.1393134. eCollection 2018. Review.


Severe Aortic Valve Regurgitation in Relapsing Polychondritis.

Rossi FW, Mercurio V, Rivellese F, Lobasso A, Barbieri L, Tocchetti CG, de Paulis A, Marone G.

J Clin Rheumatol. 2018 Mar;24(2):109-111. doi: 10.1097/RHU.0000000000000634. No abstract available.


Cardiotoxicity of immune checkpoint inhibitors.

Varricchi G, Galdiero MR, Marone G, Criscuolo G, Triassi M, Bonaduce D, Marone G, Tocchetti CG.

ESMO Open. 2017 Oct 26;2(4):e000247. doi: 10.1136/esmoopen-2017-000247. eCollection 2017. Review.


Bidirectional Mast Cell-Eosinophil Interactions in Inflammatory Disorders and Cancer.

Galdiero MR, Varricchi G, Seaf M, Marone G, Levi-Schaffer F, Marone G.

Front Med (Lausanne). 2017 Jul 24;4:103. doi: 10.3389/fmed.2017.00103. eCollection 2017. Review.


Cancer Inflammation and Cytokines.

Galdiero MR, Marone G, Mantovani A.

Cold Spring Harb Perspect Biol. 2018 Aug 1;10(8). pii: a028662. doi: 10.1101/cshperspect.a028662. Review.


Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils.

Loffredo S, Borriello F, Iannone R, Ferrara AL, Galdiero MR, Gigantino V, Esposito P, Varricchi G, Lambeau G, Cassatella MA, Granata F, Marone G.

Front Immunol. 2017 Apr 19;8:443. doi: 10.3389/fimmu.2017.00443. eCollection 2017.


Are Mast Cells MASTers in Cancer?

Varricchi G, Galdiero MR, Loffredo S, Marone G, Iannone R, Marone G, Granata F.

Front Immunol. 2017 Apr 12;8:424. doi: 10.3389/fimmu.2017.00424. eCollection 2017. Review.


Mast cells in rheumatoid arthritis: friends or foes?

Rivellese F, Nerviani A, Rossi FW, Marone G, Matucci-Cerinic M, de Paulis A, Pitzalis C.

Autoimmun Rev. 2017 Jun;16(6):557-563. doi: 10.1016/j.autrev.2017.04.001. Epub 2017 Apr 12. Review.


Immune Checkpoint Inhibitors and Cardiac Toxicity: An Emerging Issue.

Varricchi G, Marone G, Mercurio V, Galdiero MR, Bonaduce D, Tocchetti CG.

Curr Med Chem. 2018;25(11):1327-1339. doi: 10.2174/0929867324666170407125017. Review.


Lipopolysaccharide-Elicited TSLPR Expression Enriches a Functionally Discrete Subset of Human CD14+ CD1c+ Monocytes.

Borriello F, Iannone R, Di Somma S, Vastolo V, Petrosino G, Visconte F, Raia M, Scalia G, Loffredo S, Varricchi G, Galdiero MR, Granata F, Del Vecchio L, Portella G, Marone G.

J Immunol. 2017 May 1;198(9):3426-3435. doi: 10.4049/jimmunol.1601497. Epub 2017 Mar 24.


Histamine Release from Mast Cells and Basophils.

Borriello F, Iannone R, Marone G.

Handb Exp Pharmacol. 2017;241:121-139. doi: 10.1007/164_2017_18. Review.


GM-CSF and IL-3 Modulate Human Monocyte TNF-╬▒ Production and Renewal in In Vitro Models of Trained Immunity.

Borriello F, Iannone R, Di Somma S, Loffredo S, Scamardella E, Galdiero MR, Varricchi G, Granata F, Portella G, Marone G.

Front Immunol. 2017 Jan 16;7:680. doi: 10.3389/fimmu.2016.00680. eCollection 2016.


Cellular subtype expression and activation of CaMKII regulate the fate of atherosclerotic plaque.

Maione AS, Cipolletta E, Sorriento D, Borriello F, Soprano M, Rusciano MR, D'Esposito V, Markabaoui AK, De Palma GD, Martino G, Maresca L, Nobile G, Campiglia P, Formisano P, Ciccarelli M, Marone G, Trimarco B, Iaccarino G, Illario M.

Atherosclerosis. 2017 Jan;256:53-61. doi: 10.1016/j.atherosclerosis.2016.11.006. Epub 2016 Nov 5.

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