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Items: 1 to 50 of 51

1.

NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum.

Pieper A, Rudolph S, Wieser GL, Götze T, Mießner H, Yonemasu T, Yan K, Tzvetanova I, Castillo BD, Bode U, Bormuth I, Wadiche JI, Schwab MH, Goebbels S.

Sci Rep. 2019 Feb 5;9(1):1448. doi: 10.1038/s41598-018-37850-7.

2.

Investigation of Neuregulin-1 and Glial Cell-Derived Neurotrophic Factor in Rodent Astrocytes and Microglia.

Kronenberg J, Merkel L, Heckers S, Gudi V, Schwab HM, Stangel M.

J Mol Neurosci. 2019 Mar;67(3):484-493. doi: 10.1007/s12031-019-1258-8. Epub 2019 Jan 25.

PMID:
30680593
3.

Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.

Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L.

Hum Mol Genet. 2019 Jan 21. doi: 10.1093/hmg/ddz021. [Epub ahead of print] No abstract available.

PMID:
30668730
4.

Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.

Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Markus Schwab H, Nave K, Fratta P, D'Antonio M, Poitelon Y, Laura Feltri M, Wrabetz L.

Hum Mol Genet. 2018 Dec 10. doi: 10.1093/hmg/ddy420. [Epub ahead of print]

PMID:
30535360
5.

Enhanced axonal Neuregulin-1 type-III signaling ameliorates neurophysiology and hypomyelination in a Charcot-Marie-Tooth type 1B mouse model.

Scapin C, Ferri C, Pettinato E, Zambroni D, Bianchi F, Del Carro U, Belin S, Caruso D, Mitro N, Pellegatta M, Taveggia C, Schwab MH, Nave KA, Laura Feltri M, Wrabetz L, D'Antonio M.

Hum Mol Genet. 2018 Nov 27. doi: 10.1093/hmg/ddy411. [Epub ahead of print]

PMID:
30481294
6.

Altered hippocampal gene expression and structure in transgenic mice overexpressing neuregulin 1 (Nrg1) type I.

Deakin IH, Godlewska BR, Walker MA, Huang GJ, Schwab MH, Nave KA, Law AJ, Harrison PJ.

Transl Psychiatry. 2018 Oct 22;8(1):229. doi: 10.1038/s41398-018-0288-2.

7.

Changing flood frequencies under opposing late Pleistocene eastern Mediterranean climates.

Ben Dor Y, Armon M, Ahlborn M, Morin E, Erel Y, Brauer A, Schwab MJ, Tjallingii R, Enzel Y.

Sci Rep. 2018 May 31;8(1):8445. doi: 10.1038/s41598-018-25969-6.

8.

Spironolactone is an antagonist of NRG1-ERBB4 signaling and schizophrenia-relevant endophenotypes in mice.

Wehr MC, Hinrichs W, Brzózka MM, Unterbarnscheidt T, Herholt A, Wintgens JP, Papiol S, Soto-Bernardini MC, Kravchenko M, Zhang M, Nave KA, Wichert SP, Falkai P, Zhang W, Schwab MH, Rossner MJ.

EMBO Mol Med. 2017 Oct;9(10):1448-1462. doi: 10.15252/emmm.201707691.

9.

Yeast-based assays for screening 11β-HSD1 inhibitors.

Vanella R, Callari R, Weston A, Heider H, Schwab MS, Kübler E.

Microb Cell Fact. 2016 Mar 15;15:52. doi: 10.1186/s12934-016-0450-6.

10.

Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions.

Lee YI, Li Y, Mikesh M, Smith I, Nave KA, Schwab MH, Thompson WJ.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):E479-87. doi: 10.1073/pnas.1519156113. Epub 2016 Jan 11.

11.

Perceived Relevance of Educative Information on Public (Skin) Health: Results of a Representative, Population-Based Telephone Survey.

Haluza D, Schwab M, Simic S, Cervinka R, Moshammer H.

Int J Environ Res Public Health. 2015 Nov 9;12(11):14260-74. doi: 10.3390/ijerph121114260.

12.

Dysregulated expression of neuregulin-1 by cortical pyramidal neurons disrupts synaptic plasticity.

Agarwal A, Zhang M, Trembak-Duff I, Unterbarnscheidt T, Radyushkin K, Dibaj P, Martins de Souza D, Boretius S, Brzózka MM, Steffens H, Berning S, Teng Z, Gummert MN, Tantra M, Guest PC, Willig KI, Frahm J, Hell SW, Bahn S, Rossner MJ, Nave KA, Ehrenreich H, Zhang W, Schwab MH.

Cell Rep. 2014 Aug 21;8(4):1130-45. doi: 10.1016/j.celrep.2014.07.026. Epub 2014 Aug 14.

13.

Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions.

Bormuth I, Yan K, Yonemasu T, Gummert M, Zhang M, Wichert S, Grishina O, Pieper A, Zhang W, Goebbels S, Tarabykin V, Nave KA, Schwab MH.

J Neurosci. 2013 Jan 9;33(2):641-51. doi: 10.1523/JNEUROSCI.0899-12.2013.

14.

A role for Schwann cell-derived neuregulin-1 in remyelination.

Stassart RM, Fledrich R, Velanac V, Brinkmann BG, Schwab MH, Meijer D, Sereda MW, Nave KA.

Nat Neurosci. 2013 Jan;16(1):48-54. doi: 10.1038/nn.3281. Epub 2012 Dec 9.

PMID:
23222914
15.

Molecular control of Schwann cell migration along peripheral axons: keep moving!

Heermann S, Schwab MH.

Cell Adh Migr. 2013 Jan-Feb;7(1):18-22. doi: 10.4161/cam.22123. Epub 2012 Oct 17.

16.

Schwann cells migrate along axons in the absence of GDNF signaling.

Heermann S, Spittau B, Zajzon K, Schwab MH, Krieglstein K.

BMC Neurosci. 2012 Aug 3;13:92.

17.

Neuregulin 1 type III/ErbB signaling is crucial for Schwann cell colonization of sympathetic axons.

Heermann S, Schmücker J, Hinz U, Rickmann M, Unterbarnscheidt T, Schwab MH, Krieglstein K.

PLoS One. 2011;6(12):e28692. doi: 10.1371/journal.pone.0028692. Epub 2011 Dec 16.

18.

Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci.

Patzig J, Jahn O, Tenzer S, Wichert SP, de Monasterio-Schrader P, Rosfa S, Kuharev J, Yan K, Bormuth I, Bremer J, Aguzzi A, Orfaniotou F, Hesse D, Schwab MH, Möbius W, Nave KA, Werner HB.

J Neurosci. 2011 Nov 9;31(45):16369-86. doi: 10.1523/JNEUROSCI.4016-11.2011.

19.

Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.

Velanac V, Unterbarnscheidt T, Hinrichs W, Gummert MN, Fischer TM, Rossner MJ, Trimarco A, Brivio V, Taveggia C, Willem M, Haass C, Möbius W, Nave KA, Schwab MH.

Glia. 2012 Feb;60(2):203-17. doi: 10.1002/glia.21255. Epub 2011 Nov 2.

20.

In vivo imaging and noninvasive ablation of pyramidal neurons in adult NEX-CreERT2 mice.

Agarwal A, Dibaj P, Kassmann CM, Goebbels S, Nave KA, Schwab MH.

Cereb Cortex. 2012 Jul;22(7):1473-86. doi: 10.1093/cercor/bhr214. Epub 2011 Aug 31.

PMID:
21880656
21.

Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation.

Deakin IH, Nissen W, Law AJ, Lane T, Kanso R, Schwab MH, Nave KA, Lamsa KP, Paulsen O, Bannerman DM, Harrison PJ.

Cereb Cortex. 2012 Jul;22(7):1520-9. doi: 10.1093/cercor/bhr223. Epub 2011 Aug 30.

22.

NeuroD factors regulate cell fate and neurite stratification in the developing retina.

Cherry TJ, Wang S, Bormuth I, Schwab M, Olson J, Cepko CL.

J Neurosci. 2011 May 18;31(20):7365-79. doi: 10.1523/JNEUROSCI.2555-10.2011.

23.

A phenotype-based genetic association study reveals the contribution of neuregulin1 gene variants to age of onset and positive symptom severity in schizophrenia.

Papiol S, Begemann M, Rosenberger A, Friedrichs H, Ribbe K, Grube S, Schwab MH, Jahn H, Gunkel S, Benseler F, Nave KA, Ehrenreich H.

Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):340-5. doi: 10.1002/ajmg.b.31168. Epub 2011 Jan 13.

PMID:
21234898
24.

Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia.

Reich A, Spering C, Gertz K, Harms C, Gerhardt E, Kronenberg G, Nave KA, Schwab M, Tauber SC, Drinkut A, Harms K, Beier CP, Voigt A, Göbbels S, Endres M, Schulz JB.

J Neurosci. 2011 Jan 5;31(1):225-33. doi: 10.1523/JNEUROSCI.2188-10.2011.

25.

Neuron-glia signaling and the protection of axon function by Schwann cells.

Quintes S, Goebbels S, Saher G, Schwab MH, Nave KA.

J Peripher Nerv Syst. 2010 Mar;15(1):10-6. doi: 10.1111/j.1529-8027.2010.00247.x. Review.

PMID:
20433601
26.

Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice.

Deakin IH, Law AJ, Oliver PL, Schwab MH, Nave KA, Harrison PJ, Bannerman DM.

Neuroreport. 2009 Nov 25;20(17):1523-8. doi: 10.1097/WNR.0b013e328330f6e7.

27.

Yeast artificial chromosomes employed for random assembly of biosynthetic pathways and production of diverse compounds in Saccharomyces cerevisiae.

Naesby M, Nielsen SV, Nielsen CA, Green T, Tange TO, Simón E, Knechtle P, Hansson A, Schwab MS, Titiz O, Folly C, Archila RE, Maver M, van Sint Fiet S, Boussemghoune T, Janes M, Kumar AS, Sonkar SP, Mitra PP, Benjamin VA, Korrapati N, Suman I, Hansen EH, Thybo T, Goldsmith N, Sorensen AS.

Microb Cell Fact. 2009 Aug 13;8:45. doi: 10.1186/1475-2859-8-45.

28.

Genetic tracing of subpopulation neurons in the prethalamus of mice (Mus musculus).

Delaunay D, Heydon K, Miguez A, Schwab M, Nave KA, Thomas JL, Spassky N, Martinez S, Zalc B.

J Comp Neurol. 2009 Jan 1;512(1):74-83. doi: 10.1002/cne.21904.

PMID:
18973275
29.

NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse.

Karram K, Goebbels S, Schwab M, Jennissen K, Seifert G, Steinhäuser C, Nave KA, Trotter J.

Genesis. 2008 Dec;46(12):743-57. doi: 10.1002/dvg.20440.

PMID:
18924152
30.

Combined treatment of Caco-2 cells with butyrate and mesalazine inhibits cell proliferation and reduces Survivin protein level.

Schwab M, Reynders V, Steinhilber D, Stein J.

Cancer Lett. 2009 Jan 8;273(1):98-106. doi: 10.1016/j.canlet.2008.07.027. Epub 2008 Sep 6.

PMID:
18774638
31.

Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.

Brinkmann BG, Agarwal A, Sereda MW, Garratt AN, Müller T, Wende H, Stassart RM, Nawaz S, Humml C, Velanac V, Radyushkin K, Goebbels S, Fischer TM, Franklin RJ, Lai C, Ehrenreich H, Birchmeier C, Schwab MH, Nave KA.

Neuron. 2008 Aug 28;59(4):581-95. doi: 10.1016/j.neuron.2008.06.028.

32.

PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells.

Schwab M, Reynders V, Loitsch S, Shastri YM, Steinhilber D, Schröder O, Stein J.

Carcinogenesis. 2008 Jul;29(7):1407-14. doi: 10.1093/carcin/bgn118. Epub 2008 Jun 9.

PMID:
18544567
33.

The dietary histone deacetylase inhibitor sulforaphane induces human beta-defensin-2 in intestinal epithelial cells.

Schwab M, Reynders V, Loitsch S, Steinhilber D, Schröder O, Stein J.

Immunology. 2008 Oct;125(2):241-51. doi: 10.1111/j.1365-2567.2008.02834.x. Epub 2008 Mar 27.

34.

Early neuronal and glial fate restriction of embryonic neural stem cells.

Delaunay D, Heydon K, Cumano A, Schwab MH, Thomas JL, Suter U, Nave KA, Zalc B, Spassky N.

J Neurosci. 2008 Mar 5;28(10):2551-62. doi: 10.1523/JNEUROSCI.5497-07.2008.

35.

A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives.

Mottram LF, Maddox E, Schwab M, Beaufils F, Peterson BR.

Org Lett. 2007 Sep 13;9(19):3741-4. Epub 2007 Aug 17.

PMID:
17705395
36.

Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling.

Schwab M, Reynders V, Loitsch S, Steinhilber D, Stein J, Schröder O.

Mol Immunol. 2007 Jul;44(15):3625-32. Epub 2007 May 22.

PMID:
17521736
37.

Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination.

Zeger M, Popken G, Zhang J, Xuan S, Lu QR, Schwab MH, Nave KA, Rowitch D, D'Ercole AJ, Ye P.

Glia. 2007 Mar;55(4):400-11.

38.

Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice.

Goebbels S, Bormuth I, Bode U, Hermanson O, Schwab MH, Nave KA.

Genesis. 2006 Dec;44(12):611-21.

PMID:
17146780
39.

Role of nuclear hormone receptors in butyrate-mediated up-regulation of the antimicrobial peptide cathelicidin in epithelial colorectal cells.

Schwab M, Reynders V, Shastri Y, Loitsch S, Stein J, Schröder O.

Mol Immunol. 2007 Mar;44(8):2107-14. Epub 2006 Oct 19.

PMID:
17055059
40.

PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2.

Schwab M, Reynders V, Ulrich S, Zahn N, Stein J, Schröder O.

Apoptosis. 2006 Oct;11(10):1801-11.

PMID:
16927016
41.

The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone.

Ghashghaei HT, Weber J, Pevny L, Schmid R, Schwab MH, Lloyd KC, Eisenstat DD, Lai C, Anton ES.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1930-5. Epub 2006 Jan 30.

42.

Glial cells under remote control.

Nave KA, Schwab MH.

Nat Neurosci. 2005 Nov;8(11):1420-2. No abstract available.

PMID:
16251976
43.

Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2.

Goebbels S, Bode U, Pieper A, Funfschilling U, Schwab MH, Nave KA.

Genesis. 2005 Aug;42(4):247-52.

PMID:
16028233
44.

Characterization of a new family of cyclin-dependent kinase activators.

Dinarina A, Perez LH, Davila A, Schwab M, Hunt T, Nebreda AR.

Biochem J. 2005 Mar 1;386(Pt 2):349-55.

45.

Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain.

Anton ES, Ghashghaei HT, Weber JL, McCann C, Fischer TM, Cheung ID, Gassmann M, Messing A, Klein R, Schwab MH, Lloyd KC, Lai C.

Nat Neurosci. 2004 Dec;7(12):1319-28. Epub 2004 Nov 7.

PMID:
15543145
46.

Neuregulin-2 is synthesized by motor neurons and terminal Schwann cells and activates acetylcholine receptor transcription in muscle cells expressing ErbB4.

Rimer M, Prieto AL, Weber JL, Colasante C, Ponomareva O, Fromm L, Schwab MH, Lai C, Burden SJ.

Mol Cell Neurosci. 2004 Jun;26(2):271-81.

PMID:
15207852
47.

Axonal neuregulin-1 regulates myelin sheath thickness.

Michailov GV, Sereda MW, Brinkmann BG, Fischer TM, Haug B, Birchmeier C, Role L, Lai C, Schwab MH, Nave KA.

Science. 2004 Apr 30;304(5671):700-3. Epub 2004 Mar 25.

48.

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G.

Nat Cell Biol. 2004 Feb;6(2):97-105. Epub 2004 Jan 25. Erratum in: Nat Cell Biol. 2004 May;6(5):465.

PMID:
14743216
49.
50.

Computer-aided design of a PDZ domain to recognize new target sequences.

Reina J, Lacroix E, Hobson SD, Fernandez-Ballester G, Rybin V, Schwab MS, Serrano L, Gonzalez C.

Nat Struct Biol. 2002 Aug;9(8):621-7.

PMID:
12080331

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