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Items: 1 to 50 of 253

1.

Post-Translational Modifications and Diastolic Calcium Leak Associated to the Novel RyR2-D3638A Mutation Lead to CPVT in Patient-Specific hiPSC-Derived Cardiomyocytes.

Acimovic I, Refaat MM, Moreau A, Salykin A, Reiken S, Sleiman Y, Souidi M, Přibyl J, Kajava AV, Richard S, Lu JT, Chevalier P, Skládal P, Dvořak P, Rotrekl V, Marks AR, Scheinman MM, Lacampagne A, Meli AC.

J Clin Med. 2018 Nov 8;7(11). pii: E423. doi: 10.3390/jcm7110423.

2.

Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer's-like Amyloidosis.

Wilson EN, Do Carmo S, Iulita MF, Hall H, Austin GL, Jia DT, Malcolm JC, Foret MK, Marks AR, Butterfield DA, Cuello AC.

Curr Alzheimer Res. 2018;15(13):1220-1230. doi: 10.2174/1567205015666180904154446.

PMID:
30182855
3.

Index colonoscopy-related risk factors for postcolonoscopy colorectal cancers.

Tollivoro TA, Jensen CD, Marks AR, Zhao WK, Schottinger JE, Quinn VP, Ghai NR, Zauber AG, Doubeni CA, Levin TR, Fireman B, Quesenberry CP, Corley DA.

Gastrointest Endosc. 2019 Jan;89(1):168-176.e3. doi: 10.1016/j.gie.2018.08.023. Epub 2018 Aug 23.

PMID:
30144415
4.

Ryanodine receptor dysfunction in human disorders.

Kushnir A, Wajsberg B, Marks AR.

Biochim Biophys Acta Mol Cell Res. 2018 Jul 21. pii: S0167-4889(18)30184-8. doi: 10.1016/j.bbamcr.2018.07.011. [Epub ahead of print]

PMID:
30040966
5.

Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure.

Kushnir A, Santulli G, Reiken SR, Coromilas E, Godfrey SJ, Brunjes DL, Colombo PC, Yuzefpolskaya M, Sokol SI, Kitsis RN, Marks AR.

Circulation. 2018 Sep 11;138(11):1144-1154. doi: 10.1161/CIRCULATIONAHA.117.032703.

PMID:
29593014
6.

Ryanodine Receptor Structure and Function in Health and Disease.

Santulli G, Lewis D, des Georges A, Marks AR, Frank J.

Subcell Biochem. 2018;87:329-352. doi: 10.1007/978-981-10-7757-9_11. Review.

7.

Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes.

Hartel AJW, Ong P, Schroeder I, Giese MH, Shekar S, Clarke OB, Zalk R, Marks AR, Hendrickson WA, Shepard KL.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1789-E1798. doi: 10.1073/pnas.1712313115. Epub 2018 Feb 5.

8.

Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model.

Regan JN, Mikesell C, Reiken S, Xu H, Marks AR, Mohammad KS, Guise TA, Waning DL.

Front Endocrinol (Lausanne). 2017 Dec 19;8:358. doi: 10.3389/fendo.2017.00358. eCollection 2017.

9.

BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology.

Wilson EN, Do Carmo S, Iulita MF, Hall H, Ducatenzeiler A, Marks AR, Allard S, Jia DT, Windheim J, Cuello AC.

Transl Psychiatry. 2017 Aug 1;7(8):e1190. doi: 10.1038/tp.2017.169.

10.

Physiology and pathophysiology of excitation-contraction coupling: the functional role of ryanodine receptor.

Santulli G, Lewis DR, Marks AR.

J Muscle Res Cell Motil. 2017 Feb;38(1):37-45. doi: 10.1007/s10974-017-9470-z. Epub 2017 Jun 26. Review.

11.

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.

Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR.

Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19.

PMID:
28631094
12.

Structural basis for conductance through TRIC cation channels.

Su M, Gao F, Yuan Q, Mao Y, Li DL, Guo Y, Yang C, Wang XH, Bruni R, Kloss B, Zhao H, Zeng Y, Zhang FB, Marks AR, Hendrickson WA, Chen YH.

Nat Commun. 2017 May 19;8:15103. doi: 10.1038/ncomms15103.

13.

Ca2+ Release Channels Join the 'Resolution Revolution'.

Zalk R, Marks AR.

Trends Biochem Sci. 2017 Jul;42(7):543-555. doi: 10.1016/j.tibs.2017.04.005. Epub 2017 May 9. Review.

14.

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

Bussiere R, Lacampagne A, Reiken S, Liu X, Scheuerman V, Zalk R, Martin C, Checler F, Marks AR, Chami M.

J Biol Chem. 2017 Jun 16;292(24):10153-10168. doi: 10.1074/jbc.M116.743070. Epub 2017 May 5.

15.

Risk of Acute Liver Injury With Antiretroviral Therapy by Viral Hepatitis Status.

Gowda C, Newcomb CW, Liu Q, Carbonari DM, Lewis JD, Forde KA, Goldberg DS, Reddy KR, Roy JA, Marks AR, Schneider JL, Kostman JR, Tate JP, Lim JK, Justice AC, Goetz MB, Corley DA, Lo Re V.

Open Forum Infect Dis. 2017 Jan 28;4(2):ofx012. doi: 10.1093/ofid/ofx012. eCollection 2017 Spring.

16.

Association Between Time to Colonoscopy After a Positive Fecal Test Result and Risk of Colorectal Cancer and Cancer Stage at Diagnosis.

Corley DA, Jensen CD, Quinn VP, Doubeni CA, Zauber AG, Lee JK, Schottinger JE, Marks AR, Zhao WK, Ghai NR, Lee AT, Contreras R, Quesenberry CP, Fireman BH, Levin TR.

JAMA. 2017 Apr 25;317(16):1631-1641. doi: 10.1001/jama.2017.3634.

17.

Intracellular calcium release channels: an update.

Santulli G, Nakashima R, Yuan Q, Marks AR.

J Physiol. 2017 May 15;595(10):3041-3051. doi: 10.1113/JP272781. Review.

18.

Genetic Biomarker Prevalence Is Similar in Fecal Immunochemical Test Positive and Negative Colorectal Cancer Tissue.

Levin TR, Corley DA, Jensen CD, Marks AR, Zhao WK, Zebrowski AM, Quinn VP, Browne LW, Taylor WR, Ahlquist DA, Lidgard GP, Berger BM.

Dig Dis Sci. 2017 Mar;62(3):678-688. doi: 10.1007/s10620-016-4433-6. Epub 2017 Jan 2.

19.

Aromatase inhibitor-induced bone loss increases the progression of estrogen receptor-negative breast cancer in bone and exacerbates muscle weakness in vivo.

Wright LE, Harhash AA, Kozlow WM, Waning DL, Regan JN, She Y, John SK, Murthy S, Niewolna M, Marks AR, Mohammad KS, Guise TA.

Oncotarget. 2017 Jan 31;8(5):8406-8419. doi: 10.18632/oncotarget.14139.

20.

Endoscopist fatigue estimates and colonoscopic adenoma detection in a large community-based setting.

Lee A, Jensen CD, Marks AR, Zhao WK, Doubeni CA, Zauber AG, Quinn VP, Levin TR, Corley DA.

Gastrointest Endosc. 2017 Mar;85(3):601-610.e2. doi: 10.1016/j.gie.2016.09.033. Epub 2016 Oct 1.

21.

Structural Basis for Gating and Activation of RyR1.

des Georges A, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J.

Cell. 2016 Sep 22;167(1):145-157.e17. doi: 10.1016/j.cell.2016.08.075.

22.

Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation.

Matecki S, Dridi H, Jung B, Saint N, Reiken SR, Scheuermann V, Mrozek S, Santulli G, Umanskaya A, Petrof BJ, Jaber S, Marks AR, Lacampagne A.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9069-74. doi: 10.1073/pnas.1609707113. Epub 2016 Jul 25.

23.

Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS.

Yuan Q, Yang J, Santulli G, Reiken SR, Wronska A, Kim MM, Osborne BW, Lacampagne A, Yin Y, Marks AR.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8532-7. doi: 10.1073/pnas.1608859113. Epub 2016 Jul 8.

24.

The Fukushima nuclear disaster is ongoing.

Marks AR.

J Clin Invest. 2016 Jul 1;126(7):2385-7. doi: 10.1172/JCI88434. Epub 2016 May 23.

25.

Fecal Immunochemical Test Program Performance Over 4 Rounds of Annual Screening: A Retrospective Cohort Study.

Jensen CD, Corley DA, Quinn VP, Doubeni CA, Zauber AG, Lee JK, Zhao WK, Marks AR, Schottinger JE, Ghai NR, Lee AT, Contreras R, Klabunde CN, Quesenberry CP, Levin TR, Mysliwiec PA.

Ann Intern Med. 2016 Apr 5;164(7):456-63. doi: 10.7326/M15-0983. Epub 2016 Jan 26.

26.

Intraneuronal Amyloid Beta Accumulation Disrupts Hippocampal CRTC1-Dependent Gene Expression and Cognitive Function in a Rat Model of Alzheimer Disease.

Wilson EN, Abela AR, Do Carmo S, Allard S, Marks AR, Welikovitch LA, Ducatenzeiler A, Chudasama Y, Cuello AC.

Cereb Cortex. 2017 Feb 1;27(2):1501-1511. doi: 10.1093/cercor/bhv332.

27.

Oral Azole Antifungal Medications and Risk of Acute Liver Injury, Overall and by Chronic Liver Disease Status.

Lo Re V 3rd, Carbonari DM, Lewis JD, Forde KA, Goldberg DS, Reddy KR, Haynes K, Roy JA, Sha D, Marks AR, Schneider JL, Strom BL, Corley DA.

Am J Med. 2016 Mar;129(3):283-91.e5. doi: 10.1016/j.amjmed.2015.10.029. Epub 2015 Nov 17.

28.

Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

Santulli G, Pagano G, Sardu C, Xie W, Reiken S, D'Ascia SL, Cannone M, Marziliano N, Trimarco B, Guise TA, Lacampagne A, Marks AR.

J Clin Invest. 2015 Nov 2;125(11):4316. doi: 10.1172/JCI84937. Epub 2015 Nov 2. No abstract available.

29.

Excess TGF-β mediates muscle weakness associated with bone metastases in mice.

Waning DL, Mohammad KS, Reiken S, Xie W, Andersson DC, John S, Chiechi A, Wright LE, Umanskaya A, Niewolna M, Trivedi T, Charkhzarrin S, Khatiwada P, Wronska A, Haynes A, Benassi MS, Witzmann FA, Zhen G, Wang X, Cao X, Roodman GD, Marks AR, Guise TA.

Nat Med. 2015 Nov;21(11):1262-1271. doi: 10.1038/nm.3961. Epub 2015 Oct 12.

30.

Metformin use and risk of colorectal adenoma after polypectomy in patients with type 2 diabetes mellitus.

Marks AR, Pietrofesa RA, Jensen CD, Zebrowski A, Corley DA, Doubeni CA.

Cancer Epidemiol Biomarkers Prev. 2015 Nov;24(11):1692-8. doi: 10.1158/1055-9965.EPI-15-0559. Epub 2015 Sep 16.

31.

Mitochondrial calcium overload is a key determinant in heart failure.

Santulli G, Xie W, Reiken SR, Marks AR.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11389-94. doi: 10.1073/pnas.1513047112. Epub 2015 Jul 27.

32.

Mitochondrial oxidative stress promotes atrial fibrillation.

Xie W, Santulli G, Reiken SR, Yuan Q, Osborne BW, Chen BX, Marks AR.

Sci Rep. 2015 Jul 14;5:11427. doi: 10.1038/srep11427.

33.

Risk of Acute Liver Failure in Patients With Drug-Induced Liver Injury: Evaluation of Hy's Law and a New Prognostic Model.

Lo Re V 3rd, Haynes K, Forde KA, Goldberg DS, Lewis JD, Carbonari DM, Leidl KB, Reddy KR, Nezamzadeh MS, Roy J, Sha D, Marks AR, De Boer J, Schneider JL, Strom BL, Corley DA.

Clin Gastroenterol Hepatol. 2015 Dec;13(13):2360-8. doi: 10.1016/j.cgh.2015.06.020. Epub 2015 Jun 27.

34.

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

Santulli G, Marks AR.

Curr Mol Pharmacol. 2015;8(2):206-22. Review.

PMID:
25966694
35.

Validity of diagnostic codes and laboratory tests of liver dysfunction to identify acute liver failure events.

Lo Re V 3rd, Carbonari DM, Forde KA, Goldberg D, Lewis JD, Haynes K, Leidl KB, Reddy RK, Roy J, Sha D, Marks AR, Schneider JL, Strom BL, Corley DA.

Pharmacoepidemiol Drug Saf. 2015 Jul;24(7):676-83. doi: 10.1002/pds.3774. Epub 2015 Apr 10.

36.

Calcium release channel RyR2 regulates insulin release and glucose homeostasis.

Santulli G, Pagano G, Sardu C, Xie W, Reiken S, D'Ascia SL, Cannone M, Marziliano N, Trimarco B, Guise TA, Lacampagne A, Marks AR.

J Clin Invest. 2015 May;125(5):1968-78. doi: 10.1172/JCI79273. Epub 2015 Apr 6. Erratum in: J Clin Invest. 2015 Nov 2;125(11):4316.

37.

Population-representative incidence of drug-induced acute liver failure based on an analysis of an integrated health care system.

Goldberg DS, Forde KA, Carbonari DM, Lewis JD, Leidl KB, Reddy KR, Haynes K, Roy J, Sha D, Marks AR, Schneider JL, Strom BL, Corley DA, Lo Re V 3rd.

Gastroenterology. 2015 Jun;148(7):1353-61.e3. doi: 10.1053/j.gastro.2015.02.050. Epub 2015 Feb 28.

38.

Structure of a mammalian ryanodine receptor.

Zalk R, Clarke OB, des Georges A, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR.

Nature. 2015 Jan 1;517(7532):44-9. doi: 10.1038/nature13950. Epub 2014 Dec 1.

39.

Short-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions.

Cheung JW, Meli AC, Xie W, Mittal S, Reiken S, Wronska A, Xu L, Steinberg JS, Markowitz SM, Iwai S, Lacampagne A, Lerman BB, Marks AR.

Int J Cardiol. 2015 Feb 1;180:228-36. doi: 10.1016/j.ijcard.2014.11.119. Epub 2014 Nov 25.

40.

Adjusting for patient demographics has minimal effects on rates of adenoma detection in a large, community-based setting.

Jensen CD, Doubeni CA, Quinn VP, Levin TR, Zauber AG, Schottinger JE, Marks AR, Zhao WK, Lee JK, Ghai NR, Schneider JL, Fireman BH, Quesenberry CP, Corley DA.

Clin Gastroenterol Hepatol. 2015 Apr;13(4):739-46. doi: 10.1016/j.cgh.2014.10.020. Epub 2014 Oct 25.

41.

Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging.

Umanskaya A, Santulli G, Xie W, Andersson DC, Reiken SR, Marks AR.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15250-5. doi: 10.1073/pnas.1412754111. Epub 2014 Oct 6.

42.

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.

Santulli G, Wronska A, Uryu K, Diacovo TG, Gao M, Marx SO, Kitajewski J, Chilton JM, Akat KM, Tuschl T, Marks AR, Totary-Jain H.

J Clin Invest. 2014 Sep;124(9):4102-14. doi: 10.1172/JCI76069. Epub 2014 Aug 18.

43.

Prevention of vertical transmission of hepatitis B: an observational study.

Kubo A, Shlager L, Marks AR, Lakritz D, Beaumont C, Gabellini K, Corley DA.

Ann Intern Med. 2014 Jun 17;160(12):828-35. doi: 10.7326/M13-2529.

44.

Adenoma detection rate and risk of colorectal cancer and death.

Corley DA, Jensen CD, Marks AR, Zhao WK, Lee JK, Doubeni CA, Zauber AG, de Boer J, Fireman BH, Schottinger JE, Quinn VP, Ghai NR, Levin TR, Quesenberry CP.

N Engl J Med. 2014 Apr 3;370(14):1298-306. doi: 10.1056/NEJMoa1309086.

45.

Prevalence of antibiotic-resistant E. coli in retail chicken: comparing conventional, organic, kosher, and raised without antibiotics.

Millman JM, Waits K, Grande H, Marks AR, Marks JC, Price LB, Hungate BA.

Version 2. F1000Res. 2013 Jul 11 [revised 2013 Jan 1];2:155. doi: 10.12688/f1000research.2-155.v2. eCollection 2013.

46.

Long-term cardiovascular outcomes in survivors of Kawasaki disease.

Holve TJ, Patel A, Chau Q, Marks AR, Meadows A, Zaroff JG.

Pediatrics. 2014 Feb;133(2):e305-11. doi: 10.1542/peds.2013-1638. Epub 2014 Jan 20.

PMID:
24446449
47.

Imaging atrial arrhythmic intracellular calcium in intact heart.

Xie W, Santulli G, Guo X, Gao M, Chen BX, Marks AR.

J Mol Cell Cardiol. 2013 Nov;64:120-3. doi: 10.1016/j.yjmcc.2013.09.003. Epub 2013 Sep 13.

48.

Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing.

Subramanyam P, Chang DD, Fang K, Xie W, Marks AR, Colecraft HM.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15461-6. doi: 10.1073/pnas.1308161110. Epub 2013 Sep 3.

49.

Treatment of experimental asthma using a single small molecule with anti-inflammatory and BK channel-activating properties.

Goldklang MP, Perez-Zoghbi JF, Trischler J, Nkyimbeng T, Zakharov SI, Shiomi T, Zelonina T, Marks AR, D'Armiento JM, Marx SO.

FASEB J. 2013 Dec;27(12):4975-86. doi: 10.1096/fj.13-235176. Epub 2013 Aug 30.

50.

Modifications of skeletal muscle ryanodine receptor type 1 and exercise intolerance in heart failure.

Rullman E, Andersson DC, Melin M, Reiken S, Mancini DM, Marks AR, Lund LH, Gustafsson T.

J Heart Lung Transplant. 2013 Sep;32(9):925-9. doi: 10.1016/j.healun.2013.06.026.

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