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Items: 1 to 50 of 229

1.

Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics.

Indira Chandran V, Welinder C, Gonçalves de Oliveira K, Cerezo-Magaña M, Månsson AS, Johansson MC, Marko-Varga G, Belting M.

J Neurooncol. 2019 Aug 14. doi: 10.1007/s11060-019-03262-4. [Epub ahead of print]

PMID:
31414377
2.

Clusterwise Peak Detection and Filtering Based on Spatial Distribution To Efficiently Mine Mass Spectrometry Imaging Data.

Eriksson JO, Rezeli M, Hefner M, Marko-Varga G, Horvatovich P.

Anal Chem. 2019 Sep 17;91(18):11888-11896. doi: 10.1021/acs.analchem.9b02637. Epub 2019 Aug 23.

PMID:
31403280
3.

Current status of clinical proteogenomics in lung cancer.

Nishimura T, Nakamura H, Végvári Á, Marko-Varga G, Furuya N, Saji H.

Expert Rev Proteomics. 2019 Sep;16(9):761-772. doi: 10.1080/14789450.2019.1654861. Epub 2019 Aug 21.

PMID:
31402712
4.

Progressive changes in human follicular fluid composition over the course of ovulation: quantitative proteomic analyses.

Poulsen LC, Pla I, Sanchez A, Grøndahl ML, Marko-Varga G, Yding Andersen C, Englund ALM, Malm J.

Mol Cell Endocrinol. 2019 Sep 15;495:110522. doi: 10.1016/j.mce.2019.110522. Epub 2019 Jul 26.

PMID:
31356852
5.

Alpha-1-acid glycoprotein 1 is upregulated in pancreatic ductal adenocarcinoma and confers a poor prognosis.

Zhou Q, Andersson R, Hu D, Bauden M, Sasor A, Bygott T, PawŁowski K, Pla I, Marko-Varga G, Ansari D.

Transl Res. 2019 Oct;212:67-79. doi: 10.1016/j.trsl.2019.06.003. Epub 2019 Jun 29.

PMID:
31295437
6.

Proteomic profiling of extracellular vesicles reveals additional diagnostic biomarkers for myocardial infarction compared to plasma alone.

Gidlöf O, Evander M, Rezeli M, Marko-Varga G, Laurell T, Erlinge D.

Sci Rep. 2019 Jun 20;9(1):8991. doi: 10.1038/s41598-019-45473-9.

7.

Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer's disease.

Mendonça CF, Kuras M, Nogueira FCS, Plá I, Hortobágyi T, Csiba L, Palkovits M, Renner É, Döme P, Marko-Varga G, Domont GB, Rezeli M.

Neurobiol Dis. 2019 Oct;130:104509. doi: 10.1016/j.nbd.2019.104509. Epub 2019 Jun 15.

PMID:
31207390
8.

Quantitative proteomics identifies brain acid soluble protein 1 (BASP1) as a prognostic biomarker candidate in pancreatic cancer tissue.

Zhou Q, Andersson R, Hu D, Bauden M, Kristl T, Sasor A, Pawłowski K, Pla I, Hilmersson KS, Zhou M, Lu F, Marko-Varga G, Ansari D.

EBioMedicine. 2019 May;43:282-294. doi: 10.1016/j.ebiom.2019.04.008. Epub 2019 Apr 11.

9.

Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data.

Betancourt LH, Pawłowski K, Eriksson J, Szasz AM, Mitra S, Pla I, Welinder C, Ekedahl H, Broberg P, Appelqvist R, Yakovleva M, Sugihara Y, Miharada K, Ingvar C, Lundgren L, Baldetorp B, Olsson H, Rezeli M, Wieslander E, Horvatovich P, Malm J, Jönsson G, Marko-Varga G.

Sci Rep. 2019 Mar 26;9(1):5154. doi: 10.1038/s41598-019-41625-z.

10.

Clinical protein science in translational medicine targeting malignant melanoma.

Gil J, Betancourt LH, Pla I, Sanchez A, Appelqvist R, Miliotis T, Kuras M, Oskolas H, Kim Y, Horvath Z, Eriksson J, Berge E, Burestedt E, Jönsson G, Baldetorp B, Ingvar C, Olsson H, Lundgren L, Horvatovich P, Murillo JR, Sugihara Y, Welinder C, Wieslander E, Lee B, Lindberg H, Pawłowski K, Kwon HJ, Doma V, Timar J, Karpati S, Szasz AM, Németh IB, Nishimura T, Corthals G, Rezeli M, Knudsen B, Malm J, Marko-Varga G.

Cell Biol Toxicol. 2019 Mar 21. doi: 10.1007/s10565-019-09468-6. [Epub ahead of print]

PMID:
30900145
11.

Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma.

Indira Chandran V, Welinder C, Månsson AS, Offer S, Freyhult E, Pernemalm M, Lund SM, Pedersen S, Lehtiö J, Marko-Varga G, Johansson MC, Englund E, Sundgren PC, Belting M.

Clin Cancer Res. 2019 May 15;25(10):3115-3127. doi: 10.1158/1078-0432.CCR-18-2946. Epub 2019 Jan 24.

PMID:
30679164
12.

Correction: Automated phosphopeptide enrichment from minute quantities of frozen malignant melanoma tissue.

Murillo JR, Kuras M, Rezeli M, Miliotis T, Betancourt L, Marko-Varga G.

PLoS One. 2018 Dec 31;13(12):e0210234. doi: 10.1371/journal.pone.0210234. eCollection 2018.

13.

Automated phosphopeptide enrichment from minute quantities of frozen malignant melanoma tissue.

Murillo JR, Kuras M, Rezeli M, Miliotis T, Betancourt L, Marko-Varga G.

PLoS One. 2018 Dec 10;13(12):e0208562. doi: 10.1371/journal.pone.0208562. eCollection 2018. Erratum in: PLoS One. 2018 Dec 31;13(12):e0210234.

14.

Assessing Automated Sample Preparation Technologies for High-Throughput Proteomics of Frozen Well Characterized Tissues from Swedish Biobanks.

Kuras M, Betancourt LH, Rezeli M, Rodriguez J, Szasz M, Zhou Q, Miliotis T, Andersson R, Marko-Varga G.

J Proteome Res. 2019 Jan 4;18(1):548-556. doi: 10.1021/acs.jproteome.8b00792. Epub 2018 Dec 10.

PMID:
30462917
15.

Challenging the heterogeneity of disease presentation in malignant melanoma-impact on patient treatment.

Marcell Szasz A, Malm J, Rezeli M, Sugihara Y, Betancourt LH, Rivas D, Gyorffy B, Marko-Varga G.

Cell Biol Toxicol. 2019 Feb;35(1):1-14. doi: 10.1007/s10565-018-9446-9. Epub 2018 Oct 24. Review.

16.

Optimization of sample preparation for transporter protein quantification in tissues by LC-MS/MS.

Jankovskaja S, Kamiie J, Rezeli M, Gustavsson L, Sugihara Y, Miliotis T, Ruzgas T, Marko-Varga G.

J Pharm Biomed Anal. 2019 Feb 5;164:9-15. doi: 10.1016/j.jpba.2018.10.013. Epub 2018 Oct 7.

PMID:
30339949
17.

Biology/Disease-Driven Initiative on Protein-Aggregation Diseases of the Human Proteome Project: Goals and Progress to Date.

Boersema PJ, Melnik A, Hazenberg BPC, Rezeli M, Marko-Varga G, Kamiie J, Portelius E, Blennow K, Zubarev RA, Polymenidou M, Picotti P.

J Proteome Res. 2018 Dec 7;17(12):4072-4084. doi: 10.1021/acs.jproteome.8b00401. Epub 2018 Sep 28.

PMID:
30137990
18.

Biobank integration of large-scale clinical and histopathology melanoma studies within the European Cancer Moonshot Lund Center.

Malm J, Sugihara Y, Szasz M, Kwon HJ, Lindberg H, Appelqvist R, Marko-Varga G.

Clin Transl Med. 2018 Aug 20;7(1):28. doi: 10.1186/s40169-018-0203-8.

19.

Endogenous expression mapping of malignant melanoma by mass spectrometry imaging.

Sugihara Y, Rivas D, Malm J, Szasz M, Kwon H, Baldetorp B, Olsson H, Ingvar C, Rezeli M, Fehniger TE, Marko-Varga G.

Clin Transl Med. 2018 Aug 6;7(1):22. doi: 10.1186/s40169-018-0201-x.

20.

Quantitative Assessment of Urea In-Solution Lys-C/Trypsin Digestions Reveals Superior Performance at Room Temperature over Traditional Proteolysis at 37 °C.

Betancourt LH, Sanchez A, Pla I, Kuras M, Zhou Q, Andersson R, Marko-Varga G.

J Proteome Res. 2018 Jul 6;17(7):2556-2561. doi: 10.1021/acs.jproteome.8b00228. Epub 2018 Jun 7.

PMID:
29812944
21.

Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma.

Hu D, Ansari D, Pawłowski K, Zhou Q, Sasor A, Welinder C, Kristl T, Bauden M, Rezeli M, Jiang Y, Marko-Varga G, Andersson R.

Oncotarget. 2018 Jan 3;9(11):9789-9807. doi: 10.18632/oncotarget.23929. eCollection 2018 Feb 9.

22.

Evaluation of Drug Exposure and Metabolism in Locust and Zebrafish Brains Using Mass Spectrometry Imaging.

Villacrez M, Hellman K, Ono T, Sugihara Y, Rezeli M, Ek F, Marko-Varga G, Olsson R.

ACS Chem Neurosci. 2018 Aug 15;9(8):1994-2000. doi: 10.1021/acschemneuro.7b00459. Epub 2018 Jan 19.

PMID:
29350027
23.

Large Scale Identification of Variant Proteins in Glioma Stem Cells.

Mostovenko E, Végvári Á, Rezeli M, Lichti CF, Fenyö D, Wang Q, Lang FF, Sulman EP, Sahlin KB, Marko-Varga G, Nilsson CL.

ACS Chem Neurosci. 2018 Jan 17;9(1):73-79. doi: 10.1021/acschemneuro.7b00362. Epub 2017 Dec 21.

24.

Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma.

Bauden M, Kristl T, Sasor A, Andersson B, Marko-Varga G, Andersson R, Ansari D.

BMC Cancer. 2017 Dec 2;17(1):810. doi: 10.1186/s12885-017-3834-z.

25.

Pathophysiology of Meningioma Growth in Pregnancy.

Hortobágyi T, Bencze J, Murnyák B, Kouhsari MC, Bognár L, Marko-Varga G.

Open Med (Wars). 2017 Jul 13;12:195-200. doi: 10.1515/med-2017-0029. eCollection 2017.

26.

Quantitation of 87 Proteins by nLC-MRM/MS in Human Plasma: Workflow for Large-Scale Analysis of Biobank Samples.

Rezeli M, Sjödin K, Lindberg H, Gidlöf O, Lindahl B, Jernberg T, Spaak J, Erlinge D, Marko-Varga G.

J Proteome Res. 2017 Sep 1;16(9):3242-3254. doi: 10.1021/acs.jproteome.7b00235. Epub 2017 Aug 8.

PMID:
28738677
27.

[Molecular background of the melanoma and the brain metastasis].

Katona F, Murnyák B, Marko-Varga G, Hortobágyi T.

Orv Hetil. 2017 Jul;158(28):1083-1091. doi: 10.1556/650.2017.30793. Review. Hungarian.

PMID:
28691878
28.

PARP1 expression and its correlation with survival is tumour molecular subtype dependent in glioblastoma.

Murnyák B, Kouhsari MC, Hershkovitch R, Kálmán B, Marko-Varga G, Klekner Á, Hortobágyi T.

Oncotarget. 2017 Jul 11;8(28):46348-46362. doi: 10.18632/oncotarget.18013.

29.

A selected reaction monitoring mass spectrometric assessment of biomarker candidates diagnosing large-cell neuroendocrine lung carcinoma by the scaling method using endogenous references.

Fukuda T, Nomura M, Kato Y, Tojo H, Fujii K, Nagao T, Bando Y, Fehniger TE, Marko-Varga G, Nakamura H, Kato H, Nishimura T.

PLoS One. 2017 Apr 27;12(4):e0176219. doi: 10.1371/journal.pone.0176219. eCollection 2017.

30.

Correlation of histopathologic characteristics to protein expression and function in malignant melanoma.

Welinder C, Pawłowski K, Szasz AM, Yakovleva M, Sugihara Y, Malm J, Jönsson G, Ingvar C, Lundgren L, Baldetorp B, Olsson H, Rezeli M, Laurell T, Wieslander E, Marko-Varga G.

PLoS One. 2017 Apr 26;12(4):e0176167. doi: 10.1371/journal.pone.0176167. eCollection 2017.

31.

Merging clinical chemistry biomarker data with a COPD database - building a clinical infrastructure for proteomic studies.

Eriksson J, Andersson S, Appelqvist R, Wieslander E, Truedsson M, Bugge M, Malm J, Dahlbäck M, Andersson B, Fehniger TE, Marko-Varga G.

Proteome Sci. 2017 Apr 21;15:8. doi: 10.1186/s12953-017-0116-2. eCollection 2016.

32.

Relationship between tumour size and outcome in pancreatic ductal adenocarcinoma.

Ansari D, Bauden M, Bergström S, Rylance R, Marko-Varga G, Andersson R.

Br J Surg. 2017 Apr;104(5):600-607. doi: 10.1002/bjs.10471. Epub 2017 Feb 8.

PMID:
28177521
33.

FK506, an Immunosuppressive Drug, Induces Autophagy by Binding to the V-ATPase Catalytic Subunit A in Neuronal Cells.

Kim D, Hwang HY, Kim JY, Lee JY, Yoo JS, Marko-Varga G, Kwon HJ.

J Proteome Res. 2017 Jan 6;16(1):55-64. doi: 10.1021/acs.jproteome.6b00638. Epub 2016 Nov 17.

PMID:
28056508
34.

The Immune System and the Proteome.

Marko-Varga G, LaBaer J.

J Proteome Res. 2017 Jan 6;16(1):1. doi: 10.1021/acs.jproteome.6b00607. No abstract available.

PMID:
28056507
35.

Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors.

Torok S, Rezeli M, Kelemen O, Vegvari A, Watanabe K, Sugihara Y, Tisza A, Marton T, Kovacs I, Tovari J, Laszlo V, Helbich TH, Hegedus B, Klikovits T, Hoda MA, Klepetko W, Paku S, Marko-Varga G, Dome B.

Theranostics. 2017 Jan 1;7(2):400-412. doi: 10.7150/thno.16767. eCollection 2017.

36.

Clinical protein science developments for patient monitoring in hospital central laboratories.

Malm J, Marko-Varga G.

Clin Transl Med. 2016 Dec;5(1):47. Epub 2016 Dec 19.

37.

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

Vialas V, Colomé-Calls N, Abian J, Aloria K, Alvarez-Llamas G, Antúnez O, Arizmendi JM, Azkargorta M, Barceló-Batllori S, Barderas MG, Blanco F, Casal JI, Casas V, de la Torre C, Chicano-Gálvez E, Elortza F, Espadas G, Estanyol JM, Fernandez-Irigoyen J, Fernandez-Puente P, Fidalgo MJ, Fuentes M, Gay M, Gil C, Hainard A, Hernaez ML, Ibarrola N, Kopylov AT, Lario A, Lopez JA, López-Lucendo M, Marcilla M, Marina-Ramírez A, Marko-Varga G, Martín L, Mora MI, Morato-López E, Muñoz J, Odena MA, de Oliveira E, Orera I, Ortea I, Pasquarello C, Ray KB, Rezeli M, Ruppen I, Sabidó E, Del Pino MMS, Sancho J, Santamaría E, Vazquez J, Vilaseca M, Vivanco F, Walters JJ, Zgoda VG, Corrales FJ, Canals F, Paradela A.

J Proteomics. 2017 Jan 30;152:138-149. doi: 10.1016/j.jprot.2016.10.014. Epub 2016 Oct 29.

PMID:
27989941
38.

Characterization of histone-related chemical modifications in formalin-fixed paraffin-embedded and fresh-frozen human pancreatic cancer xenografts using LC-MS/MS.

Bauden M, Kristl T, Andersson R, Marko-Varga G, Ansari D.

Lab Invest. 2017 Mar;97(3):279-288. doi: 10.1038/labinvest.2016.134. Epub 2016 Dec 12.

39.

Combining gas-phase electrophoretic mobility molecular analysis (GEMMA), light scattering, field flow fractionation and cryo electron microscopy in a multidimensional approach to characterize liposomal carrier vesicles.

Urey C, Weiss VU, Gondikas A, von der Kammer F, Hofmann T, Marchetti-Deschmann M, Allmaier G, Marko-Varga G, Andersson R.

Int J Pharm. 2016 Nov 20;513(1-2):309-318. doi: 10.1016/j.ijpharm.2016.09.049. Epub 2016 Sep 14.

40.

Intra-tumour IgA1 is common in cancer and is correlated with poor prognosis in bladder cancer.

Welinder C, Jirström K, Lehn S, Nodin B, Marko-Varga G, Blixt O, Danielsson L, Jansson B.

Heliyon. 2016 Aug 16;2(8):e00143. doi: 10.1016/j.heliyon.2016.e00143. eCollection 2016 Aug.

41.

Cancer heterogeneity determined by functional proteomics.

Szász AM, Győrffy B, Marko-Varga G.

Semin Cell Dev Biol. 2017 Apr;64:132-142. doi: 10.1016/j.semcdb.2016.08.026. Epub 2016 Aug 26. Review.

PMID:
27569188
42.

Nano electrospray gas-phase electrophoretic mobility molecular analysis (nES GEMMA) of liposomes: applicability of the technique for nano vesicle batch control.

Weiss VU, Urey C, Gondikas A, Golesne M, Friedbacher G, von der Kammer F, Hofmann T, Andersson R, Marko-Varga G, Marchetti-Deschmann M, Allmaier G.

Analyst. 2016 Oct 17;141(21):6042-6050.

43.

Comparative Proteomic Analysis of Extracellular Vesicles Isolated by Acoustic Trapping or Differential Centrifugation.

Rezeli M, Gidlöf O, Evander M, Bryl-Górecka P, Sathanoori R, Gilje P, Pawłowski K, Horvatovich P, Erlinge D, Marko-Varga G, Laurell T.

Anal Chem. 2016 Sep 6;88(17):8577-86. doi: 10.1021/acs.analchem.6b01694. Epub 2016 Aug 16.

PMID:
27487081
44.

Building the basis for proteomics in personalized medicine for targeted treatment.

Kwon HJ, Fehniger TE, Marko-Varga G.

Clin Transl Med. 2016 Dec;5(1):19. doi: 10.1186/s40169-016-0096-3. Epub 2016 May 20. No abstract available.

45.

Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells.

Bourseau-Guilmain E, Menard JA, Lindqvist E, Indira Chandran V, Christianson HC, Cerezo Magaña M, Lidfeldt J, Marko-Varga G, Welinder C, Belting M.

Nat Commun. 2016 Apr 20;7:11371. doi: 10.1038/ncomms11371.

46.

Localization of tamoxifen in human breast cancer tumors by MALDI mass spectrometry imaging.

Végvári Á, Shavkunov AS, Fehniger TE, Grabau D, Niméus E, Marko-Varga G.

Clin Transl Med. 2016 Mar;5(1):10. doi: 10.1186/s40169-016-0090-9. Epub 2016 Mar 10.

47.

Biomarkers of early chronic obstructive pulmonary disease (COPD) in smokers and former smokers. Protocol of a longitudinal study.

Truedsson M, Malm J, Barbara Sahlin K, Bugge M, Wieslander E, Dahlbäck M, Appelqvist R, Fehniger TE, Marko-Varga G.

Clin Transl Med. 2016 Mar;5(1):9. doi: 10.1186/s40169-016-0086-5. Epub 2016 Mar 7.

48.

Cholangiocarcinoma--current classification and challenges towards personalised medicine.

Byrling J, Andersson B, Andersson R, Marko-Varga G.

Scand J Gastroenterol. 2016;51(6):641-3. doi: 10.3109/00365521.2015.1127409. Epub 2016 Jan 25. No abstract available.

PMID:
26806118
49.

Developments of mass spectrometry-based technologies for effective drug development linked with clinical proteomes.

Nakayama N, Bando Y, Fukuda T, Kawamura T, Nakamura H, Marko-Varga G, Nishimura T.

Drug Metab Pharmacokinet. 2016 Feb;31(1):3-11. doi: 10.1016/j.dmpk.2015.11.008. Epub 2015 Dec 17. Review.

PMID:
26782309
50.

Semi-automated biobank sample processing with a 384 high density sample tube robot used in cancer and cardiovascular studies.

Malm J, Lindberg H, Erlinge D, Appelqvist R, Yakovleva M, Welinder C, Steinfelder E, Fehniger TE, Marko-Varga G.

Clin Transl Med. 2015 Dec;4(1):67. doi: 10.1186/s40169-015-0067-0. Epub 2015 Aug 14.

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