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Items: 13

1.

Role of Polyubiquitin Chain Flexibility in the Catalytic Mechanism of Cullin-RING Ubiquitin Ligases.

Markin CJ, Mercier P, Spyracopoulos L.

J Phys Chem B. 2019 Jan 31;123(4):776-786. doi: 10.1021/acs.jpcb.8b10706. Epub 2019 Jan 17.

PMID:
30590923
2.

An Open-Source, Programmable Pneumatic Setup for Operation and Automated Control of Single- and Multi-Layer Microfluidic Devices.

Brower K, Puccinelli R, Markin CJ, Shimko TC, Longwell SA, Cruz B, Gomez-Sjoberg R, Fordyce PM.

HardwareX. 2018 Apr;3:117-134. doi: 10.1016/j.ohx.2017.10.001. Epub 2017 Oct 31.

3.

Two Years in the Life of a University Hospital Tobacco Cessation Service: Recommendations for Improving the Quality of Referrals.

Bjornson WG, Gonzales DH, Markin CJ, Clemons N, Favela F, Coleman TM, Koudelka C, Lapidus JA.

Jt Comm J Qual Patient Saf. 2016 May;42(5):209-18.

PMID:
27066924
4.

Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.

Hodge CD, Edwards RA, Markin CJ, McDonald D, Pulvino M, Huen MS, Zhao J, Spyracopoulos L, Hendzel MJ, Glover JN.

ACS Chem Biol. 2015 Jul 17;10(7):1718-28. doi: 10.1021/acschembio.5b00222. Epub 2015 May 1.

5.

Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.

Rout MK, Hodge CD, Markin CJ, Xu X, Glover JN, Xiao W, Spyracopoulos L.

J Am Chem Soc. 2014 Dec 17;136(50):17446-58. doi: 10.1021/ja505440b. Epub 2014 Dec 5.

PMID:
25423605
6.

Molecular basis for impaired DNA damage response function associated with the RAP80 ΔE81 defect.

Anamika, Markin CJ, Rout MK, Spyracopoulos L.

J Biol Chem. 2014 May 2;289(18):12852-62. doi: 10.1074/jbc.M113.538280. Epub 2014 Mar 13.

7.

Accuracy and precision of protein-ligand interaction kinetics determined from chemical shift titrations.

Markin CJ, Spyracopoulos L.

J Biomol NMR. 2012 Dec;54(4):355-76. doi: 10.1007/s10858-012-9678-6. Epub 2012 Oct 21.

PMID:
23086713
8.

Increased precision for analysis of protein-ligand dissociation constants determined from chemical shift titrations.

Markin CJ, Spyracopoulos L.

J Biomol NMR. 2012 Jun;53(2):125-38. doi: 10.1007/s10858-012-9630-9. Epub 2012 Apr 26.

PMID:
22534787
9.

Catalytic proficiency of ubiquitin conjugation enzymes: balancing pK(a) suppression, entropy, and electrostatics.

Markin CJ, Saltibus LF, Kean MJ, McKay RT, Xiao W, Spyracopoulos L.

J Am Chem Soc. 2010 Dec 22;132(50):17775-86. doi: 10.1021/ja105267w. Epub 2010 Nov 29.

PMID:
21114314
10.

Context-dependent remodeling of structure in two large protein fragments.

Schellenberg MJ, Ritchie DB, Wu T, Markin CJ, Spyracopoulos L, MacMillan AM.

J Mol Biol. 2010 Oct 1;402(4):720-30. doi: 10.1016/j.jmb.2010.08.020. Epub 2010 Aug 14.

PMID:
20713060
11.

Mechanism for recognition of polyubiquitin chains: balancing affinity through interplay between multivalent binding and dynamics.

Markin CJ, Xiao W, Spyracopoulos L.

J Am Chem Soc. 2010 Aug 18;132(32):11247-58. doi: 10.1021/ja103869x.

PMID:
20698691
12.

Dynamics of the RING domain from human TRAF6 by 15N NMR spectroscopy: implications for biological function.

Markin CJ, Saltibus LF, Spyracopoulos L.

Biochemistry. 2008 Sep 23;47(38):10010-7. doi: 10.1021/bi800252x. Epub 2008 Aug 30.

PMID:
18759459
13.

Fiberoptic bronchoscopy for diagnosis and treatment.

Liebler JM, Markin CJ.

Crit Care Clin. 2000 Jan;16(1):83-100. Review.

PMID:
10650501

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