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Items: 6


Focused ultrasound as a novel strategy for noninvasive gene delivery to retinal Müller glia.

Touahri Y, Dixit R, Kofoed RH, Miloska K, Park E, Raeisossadati R, Markham-Coultes K, David LA, Rijal H, Zhao J, Lynch M, Hynynen K, Aubert I, Schuurmans C.

Theranostics. 2020 Feb 10;10(7):2982-2999. doi: 10.7150/thno.42611. eCollection 2020.


Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer's disease.

Xhima K, Markham-Coultes K, Nedev H, Heinen S, Saragovi HU, Hynynen K, Aubert I.

Sci Adv. 2020 Jan 22;6(4):eaax6646. doi: 10.1126/sciadv.aax6646. eCollection 2020 Jan.


Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer's disease.

Liu M, Jevtic S, Markham-Coultes K, Ellens NPK, O'Reilly MA, Hynynen K, Aubert I, McLaurin J.

Brain Res. 2018 Jan 1;1678:138-145. doi: 10.1016/j.brainres.2017.10.015. Epub 2017 Oct 21.


Gene delivery to the spinal cord using MRI-guided focused ultrasound.

Weber-Adrian D, Thévenot E, O'Reilly MA, Oakden W, Akens MK, Ellens N, Markham-Coultes K, Burgess A, Finkelstein J, Yee AJ, Whyne CM, Foust KD, Kaspar BK, Stanisz GJ, Chopra R, Hynynen K, Aubert I.

Gene Ther. 2015 Jul;22(7):568-77. doi: 10.1038/gt.2015.25. Epub 2015 Apr 23.


Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice.

Kanemoto S, Griffin J, Markham-Coultes K, Aubert I, Tandon A, George-Hyslop PS, Fraser PE.

Neuroscience. 2014 Mar 7;261:52-9. doi: 10.1016/j.neuroscience.2013.12.021. Epub 2013 Dec 20.


Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound.

Jordão JF, Thévenot E, Markham-Coultes K, Scarcelli T, Weng YQ, Xhima K, O'Reilly M, Huang Y, McLaurin J, Hynynen K, Aubert I.

Exp Neurol. 2013 Oct;248:16-29. doi: 10.1016/j.expneurol.2013.05.008. Epub 2013 May 21.

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