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Items: 22


Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling.

Kugeratski FG, Atkinson SJ, Neilson LJ, Lilla S, Knight JRP, Serneels J, Juin A, Ismail S, Bryant DM, Markert EK, Machesky LM, Mazzone M, Sansom OJ, Zanivan S.

Sci Signal. 2019 Feb 5;12(567). pii: eaan8247. doi: 10.1126/scisignal.aan8247.


A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.

Hewit K, Sandilands E, Martinez RS, James D, Leung HY, Bryant DM, Shanks E, Markert EK.

Cell Death Dis. 2018 Oct 19;9(11):1069. doi: 10.1038/s41419-018-1115-7.


Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer.

Halim S, Markert EK, Vazquez A.

Br J Cancer. 2018 Oct;119(7):855-863. doi: 10.1038/s41416-018-0253-0. Epub 2018 Oct 5.


ΔNp63 regulates the expression of hyaluronic acid-related genes in breast cancer cells.

Gatti V, Fierro C, Compagnone M, Giangrazi F, Markert EK, Bongiorno-Borbone L, Melino G, Peschiaroli A.

Oncogenesis. 2018 Aug 24;7(8):65. doi: 10.1038/s41389-018-0073-3.


ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis.

Compagnone M, Gatti V, Presutti D, Ruberti G, Fierro C, Markert EK, Vousden KH, Zhou H, Mauriello A, Anemone L, Bongiorno-Borbone L, Melino G, Peschiaroli A.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13254-13259. doi: 10.1073/pnas.1711777114. Epub 2017 Nov 21.


Cancer metabolism at a glance.

Vazquez A, Kamphorst JJ, Markert EK, Schug ZT, Tardito S, Gottlieb E.

J Cell Sci. 2016 Sep 15;129(18):3367-73. doi: 10.1242/jcs.181016. Review.


Mathematical models of cancer metabolism.

Markert EK, Vazquez A.

Cancer Metab. 2015 Dec 22;3:14. doi: 10.1186/s40170-015-0140-6. eCollection 2015. Review.


p63 controls cell migration and invasion by transcriptional regulation of MTSS1.

Giacobbe A, Compagnone M, Bongiorno-Borbone L, Antonov A, Markert EK, Zhou JH, Annicchiarico-Petruzzelli M, Melino G, Peschiaroli A.

Oncogene. 2016 Mar 24;35(12):1602-8. doi: 10.1038/onc.2015.230. Epub 2015 Jun 29.


TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.

Amelio I, Inoue S, Markert EK, Levine AJ, Knight RA, Mak TW, Melino G.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):226-31. doi: 10.1073/pnas.1410609111. Epub 2014 Dec 22.


Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling.

Weissmueller S, Manchado E, Saborowski M, Morris JP 4th, Wagenblast E, Davis CA, Moon SH, Pfister NT, Tschaharganeh DF, Kitzing T, Aust D, Markert EK, Wu J, Grimmond SM, Pilarsky C, Prives C, Biankin AV, Lowe SW.

Cell. 2014 Apr 10;157(2):382-394. doi: 10.1016/j.cell.2014.01.066.


p73 regulates serine biosynthesis in cancer.

Amelio I, Markert EK, Rufini A, Antonov AV, Sayan BS, Tucci P, Agostini M, Mineo TC, Levine AJ, Melino G.

Oncogene. 2014 Oct 16;33(42):5039-46. doi: 10.1038/onc.2013.456. Epub 2013 Nov 4.


MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells.

Formosa A, Markert EK, Lena AM, Italiano D, Finazzi-Agro' E, Levine AJ, Bernardini S, Garabadgiu AV, Melino G, Candi E.

Oncogene. 2014 Oct 30;33(44):5173-82. doi: 10.1038/onc.2013.451. Epub 2013 Oct 28.


Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.

Tedeschi PM, Markert EK, Gounder M, Lin H, Dvorzhinski D, Dolfi SC, Chan LL, Qiu J, DiPaola RS, Hirshfield KM, Boros LG, Bertino JR, Oltvai ZN, Vazquez A.

Cell Death Dis. 2013 Oct 24;4:e877. doi: 10.1038/cddis.2013.393.


p63 regulates glutaminase 2 expression.

Giacobbe A, Bongiorno-Borbone L, Bernassola F, Terrinoni A, Markert EK, Levine AJ, Feng Z, Agostini M, Zolla L, Agrò AF, Notterman DA, Melino G, Peschiaroli A.

Cell Cycle. 2013 May 1;12(9):1395-405. doi: 10.4161/cc.24478. Epub 2013 Apr 10.


Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes.

Riis ML, Lüders T, Markert EK, Haakensen VD, Nesbakken AJ, Kristensen VN, Bukholm IR.

ISRN Oncol. 2012;2012:450267. doi: 10.5402/2012/450267. Epub 2012 Nov 26.


Proliferation and tissue remodeling in cancer: the hallmarks revisited.

Markert EK, Levine AJ, Vazquez A.

Cell Death Dis. 2012 Oct 4;3:e397. doi: 10.1038/cddis.2012.140.


Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer.

Tucci P, Agostini M, Grespi F, Markert EK, Terrinoni A, Vousden KH, Muller PA, Dötsch V, Kehrloesser S, Sayan BS, Giaccone G, Lowe SW, Takahashi N, Vandenabeele P, Knight RA, Levine AJ, Melino G.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15312-7. Epub 2012 Sep 4. Erratum in: Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2855.


miR-143 regulates hexokinase 2 expression in cancer cells.

Peschiaroli A, Giacobbe A, Formosa A, Markert EK, Bongiorno-Borbone L, Levine AJ, Candi E, D'Alessandro A, Zolla L, Finazzi Agrò A, Melino G.

Oncogene. 2013 Feb 7;32(6):797-802. doi: 10.1038/onc.2012.100. Epub 2012 Apr 2.


DNA methylation silences miR-132 in prostate cancer.

Formosa A, Lena AM, Markert EK, Cortelli S, Miano R, Mauriello A, Croce N, Vandesompele J, Mestdagh P, Finazzi-Agrò E, Levine AJ, Melino G, Bernardini S, Candi E.

Oncogene. 2013 Jan 3;32(1):127-34. doi: 10.1038/onc.2012.14. Epub 2012 Feb 6.


Molecular classification of prostate cancer using curated expression signatures.

Markert EK, Mizuno H, Vazquez A, Levine AJ.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21276-81. doi: 10.1073/pnas.1117029108. Epub 2011 Nov 28.


Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation.

Vazquez A, Markert EK, Oltvai ZN.

PLoS One. 2011;6(11):e25881. doi: 10.1371/journal.pone.0025881. Epub 2011 Nov 2.


Higher order Boolean networks as models of cell state dynamics.

Markert EK, Baas N, Levine AJ, Vazquez A.

J Theor Biol. 2010 Jun 7;264(3):945-51. doi: 10.1016/j.jtbi.2010.03.015. Epub 2010 Mar 18.


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