Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 8

1.

Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7.

Hu S, Marineau JJ, Rajagopal N, Hamman KB, Choi YJ, Schmidt DR, Ke N, Johannessen L, Bradley MJ, Orlando DA, Alnemy SR, Ren Y, Ciblat S, Winter DK, Kabro A, Sprott KT, Hodgson JG, Fritz CC, Carulli JP, di Tomaso E, Olson ER.

Cancer Res. 2019 Jul 1;79(13):3479-3491. doi: 10.1158/0008-5472.CAN-19-0119. Epub 2019 May 7.

PMID:
31064851
2.

Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent.

Xiang M, Kim H, Ho VT, Walker SR, Bar-Natan M, Anahtar M, Liu S, Toniolo PA, Kroll Y, Jones N, Giaccone ZT, Heppler LN, Ye DQ, Marineau JJ, Shaw D, Bradner JE, Blonquist T, Neuberg D, Hetz C, Stone RM, Soiffer RJ, Frank DA.

Blood. 2016 Oct 6;128(14):1845-1853. doi: 10.1182/blood-2015-07-660506. Epub 2016 Aug 16.

3.

Structure-guided DOT1L probe optimization by label-free ligand displacement.

Yi JS, Federation AJ, Qi J, Dhe-Paganon S, Hadler M, Xu X, St Pierre R, Varca AC, Wu L, Marineau JJ, Smith WB, Souza A, Chory EJ, Armstrong SA, Bradner JE.

ACS Chem Biol. 2015 Mar 20;10(3):667-74. doi: 10.1021/cb500796d. Epub 2015 Jan 15.

4.

Biased multicomponent reactions to develop novel bromodomain inhibitors.

McKeown MR, Shaw DL, Fu H, Liu S, Xu X, Marineau JJ, Huang Y, Zhang X, Buckley DL, Kadam A, Zhang Z, Blacklow SC, Qi J, Zhang W, Bradner JE.

J Med Chem. 2014 Nov 13;57(21):9019-27. doi: 10.1021/jm501120z. Epub 2014 Oct 31.

5.

7,9-Diaryl-1,6,8-trioxaspiro[4.5]dec-3-en-2-ones: readily accessible and highly potent anticancer compounds.

D'Erasmo MP, Smith WB, Munoz A, Mohandas P, Au AS, Marineau JJ, Quadri LE, Bradner JE, Murelli RP.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):4035-8. doi: 10.1016/j.bmcl.2014.05.102. Epub 2014 Jun 12.

6.

Genome-wide localization of small molecules.

Anders L, Guenther MG, Qi J, Fan ZP, Marineau JJ, Rahl PB, Lovén J, Sigova AA, Smith WB, Lee TI, Bradner JE, Young RA.

Nat Biotechnol. 2014 Jan;32(1):92-6. doi: 10.1038/nbt.2776. Epub 2013 Dec 15.

7.

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.

Yu W, Chory EJ, Wernimont AK, Tempel W, Scopton A, Federation A, Marineau JJ, Qi J, Barsyte-Lovejoy D, Yi J, Marcellus R, Iacob RE, Engen JR, Griffin C, Aman A, Wienholds E, Li F, Pineda J, Estiu G, Shatseva T, Hajian T, Al-Awar R, Dick JE, Vedadi M, Brown PJ, Arrowsmith CH, Bradner JE, Schapira M.

Nat Commun. 2012;3:1288. doi: 10.1038/ncomms2304. Erratum in: Nat Commun. 2013;4:1893.

PMID:
23250418
8.

Development and evaluation of a solid-supported cyclobutadieneiron tricarbonyl complex for parallel synthesis applications.

Marineau JJ, Snapper ML.

ACS Comb Sci. 2012 Jun 11;14(6):343-6. doi: 10.1021/co2002069. Epub 2012 May 16.

PMID:
22578077

Supplemental Content

Loading ...
Support Center