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Items: 1 to 50 of 240

1.

Models for Understanding Resistance to Chemotherapy in Liver Cancer.

Marin JJG, Herraez E, Lozano E, Macias RIR, Briz O.

Cancers (Basel). 2019 Oct 29;11(11). pii: E1677. doi: 10.3390/cancers11111677. Review.

2.

Sensitizing gastric adenocarcinoma to chemotherapy by pharmacological manipulation of drug transporters.

Al-Abdulla R, Perez-Silva L, Lozano E, Macias RIR, Herraez E, Abad M, Segues N, Bujanda L, Briz O, Marin JJG.

Biochem Pharmacol. 2019 Oct 24;171:113682. doi: 10.1016/j.bcp.2019.113682. [Epub ahead of print]

PMID:
31669256
3.

Integrating a gait analysis test in hospital rehabilitation: A service design approach.

Marín J, Blanco T, Marín JJ, Moreno A, Martitegui E, Aragüés JC.

PLoS One. 2019 Oct 30;14(10):e0224409. doi: 10.1371/journal.pone.0224409. eCollection 2019.

4.

Role of transportome in the pharmacogenomics of hepatocellular carcinoma and hepatobiliary cancer.

Alonso-Peña M, Espinosa-Escudero RA, Soto-Muñiz M, Sanchon-Sanchez P, Sanchez-Martin A, Marin JJ.

Pharmacogenomics. 2019 Aug;20(13):957-970. doi: 10.2217/pgs-2019-0033.

PMID:
31486734
5.

Hepatoprotection of Mentha aquatica L., Lavandula dentata L. and Leonurus cardiaca L.

Pereira OR, Macias RIR, Domingues MRM, Marin JJG, Cardoso SM.

Antioxidants (Basel). 2019 Aug 2;8(8). pii: E267. doi: 10.3390/antiox8080267.

6.

Leishmania heme uptake involves LmFLVCRb, a novel porphyrin transporter essential for the parasite.

Cabello-Donayre M, Orrego LM, Herráez E, Vargas P, Martínez-García M, Campos-Salinas J, Pérez-Victoria I, Vicente B, Marín JJG, Pérez-Victoria JM.

Cell Mol Life Sci. 2019 Aug 1. doi: 10.1007/s00018-019-03258-3. [Epub ahead of print]

PMID:
31372684
7.

What "The Cancer Genome Atlas" database tells us about the role of ATP-binding cassette (ABC) proteins in chemoresistance to anticancer drugs.

Briz O, Perez-Silva L, Al-Abdulla R, Abete L, Reviejo M, Romero MR, Marin JJG.

Expert Opin Drug Metab Toxicol. 2019 Jul;15(7):577-593. doi: 10.1080/17425255.2019.1631285. Epub 2019 Jun 23. Review.

PMID:
31185182
8.

New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools.

Muñoz-Galván S, Felipe-Abrio B, García-Carrasco M, Domínguez-Piñol J, Suarez-Martinez E, Verdugo-Sivianes EM, Espinosa-Sánchez A, Navas LE, Otero-Albiol D, Marin JJ, Jiménez-García MP, García-Heredia JM, Quiroga AG, Estevez-Garcia P, Carnero A.

J Exp Clin Cancer Res. 2019 Jun 3;38(1):234. doi: 10.1186/s13046-019-1245-5.

9.

Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy.

Lozano E, Macias RIR, Monte MJ, Asensio M, Del Carmen S, Sanchez-Vicente L, Alonso-Peña M, Al-Abdulla R, Munoz-Garrido P, Satriano L, O'Rourke CJ, Banales JM, Avila MA, Martinez-Chantar ML, Andersen JB, Briz O, Marin JJG.

Hepatology. 2019 Oct;70(4):1246-1261. doi: 10.1002/hep.30656. Epub 2019 May 20.

PMID:
30972782
10.

Evaluation of the promiscuous component of several bacterial export pumps TolC as a biomarker for toxic pollutants in feedstuffs.

Perez-Silva L, Sanchez-Vicente L, Molina-Alcaide E, Marin JJG, Herraez E.

Chem Biol Interact. 2019 May 25;305:195-202. doi: 10.1016/j.cbi.2019.03.028. Epub 2019 Mar 30.

PMID:
30940451
11.

Mechanisms of Anticancer Drug Resistance in Hepatoblastoma.

Marin JJG, Cives-Losada C, Asensio M, Lozano E, Briz O, Macias RIR.

Cancers (Basel). 2019 Mar 22;11(3). pii: E407. doi: 10.3390/cancers11030407. Review.

12.

Signalling networks in cholangiocarcinoma: Molecular pathogenesis, targeted therapies and drug resistance.

Fouassier L, Marzioni M, Afonso MB, Dooley S, Gaston K, Giannelli G, Rodrigues CMP, Lozano E, Mancarella S, Segatto O, Vaquero J, Marin JJG, Coulouarn C.

Liver Int. 2019 May;39 Suppl 1:43-62. doi: 10.1111/liv.14102. Review.

13.

Unraveling 'The Cancer Genome Atlas' information on the role of SLC transporters in anticancer drug uptake.

Al-Abdulla R, Perez-Silva L, Abete L, Romero MR, Briz O, Marin JJG.

Expert Rev Clin Pharmacol. 2019 Apr;12(4):329-341. doi: 10.1080/17512433.2019.1581605. Epub 2019 Feb 26. Review.

PMID:
30744443
14.

Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps.

Di Giacomo S, Briz O, Monte MJ, Sanchez-Vicente L, Abete L, Lozano E, Mazzanti G, Di Sotto A, Marin JJG.

Arch Toxicol. 2019 Mar;93(3):623-634. doi: 10.1007/s00204-019-02395-9. Epub 2019 Jan 18.

PMID:
30659321
15.

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib.

Al-Abdulla R, Lozano E, Macias RIR, Monte MJ, Briz O, O'Rourke CJ, Serrano MA, Banales JM, Avila MA, Martinez-Chantar ML, Geier A, Andersen JB, Marin JJG.

Br J Pharmacol. 2019 Mar;176(6):787-800. doi: 10.1111/bph.14563. Epub 2019 Feb 11.

PMID:
30592786
16.

Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients.

Rau M, Schmitt J, Berg T, Kremer AE, Stieger B, Spanaus K, Bengsch B, Romero MR, Marin JJ, Keitel V, Klinker H, Tony HP, Müllhaupt B, Geier A.

PLoS One. 2018 Dec 3;13(12):e0208225. doi: 10.1371/journal.pone.0208225. eCollection 2018.

17.

Wnt-β-catenin signalling in liver development, health and disease.

Perugorria MJ, Olaizola P, Labiano I, Esparza-Baquer A, Marzioni M, Marin JJG, Bujanda L, Banales JM.

Nat Rev Gastroenterol Hepatol. 2019 Feb;16(2):121-136. doi: 10.1038/s41575-018-0075-9. Review.

PMID:
30451972
18.

The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis.

Santamaría E, Rodríguez-Ortigosa CM, Uriarte I, Latasa MU, Urtasun R, Alvarez-Sola G, Bárcena-Varela M, Colyn L, Arcelus S, Jiménez M, Deutschmann K, Peleteiro-Vigil A, Gómez-Cambronero J, Milkiewicz M, Milkiewicz P, Sangro B, Keitel V, Monte MJ, Marin JJG, Fernández-Barrena MG, Ávila MA, Berasain C.

Hepatology. 2019 Apr;69(4):1632-1647. doi: 10.1002/hep.30348. Epub 2019 Mar 4.

PMID:
30411380
19.

Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis.

Banales JM, Iñarrairaegui M, Arbelaiz A, Milkiewicz P, Muntané J, Muñoz-Bellvis L, La Casta A, Gonzalez LM, Arretxe E, Alonso C, Martínez-Arranz I, Lapitz A, Santos-Laso A, Avila MA, Martínez-Chantar ML, Bujanda L, Marin JJG, Sangro B, Macias RIR.

Hepatology. 2019 Aug;70(2):547-562. doi: 10.1002/hep.30319. Epub 2019 Feb 14.

20.

Cervical Spine Assessment Using Passive and Active Mobilization Recorded Through an Optical Motion Capture.

Moreno AJ, Utrilla G, Marin J, Marin JJ, Sanchez-Valverde MB, Royo AC.

J Chiropr Med. 2018 Sep;17(3):167-181. doi: 10.1016/j.jcm.2017.12.004. Epub 2018 Sep 15.

21.

Role of drug transporters in the sensitivity of acute myeloid leukemia to sorafenib.

Macias RIR, Sánchez-Martín A, Rodríguez-Macías G, Sánchez-Abarca LI, Lozano E, Herraez E, Odero MD, Díez-Martín JL, Marin JJG, Briz O.

Oncotarget. 2018 Jun 19;9(47):28474-28485. doi: 10.18632/oncotarget.25494. eCollection 2018 Jun 19.

22.

Role of the placenta in serum autotaxin elevation during maternal cholestasis.

Macias RIR, Matilla S, Lozano E, Estiú MC, Oude Elferink RP, Marin JJG.

Am J Physiol Gastrointest Liver Physiol. 2018 Sep 1;315(3):G399-G407. doi: 10.1152/ajpgi.00112.2018. Epub 2018 Jun 21.

23.

Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk.

Al-Aqil FA, Monte MJ, Peleteiro-Vigil A, Briz O, Rosales R, González R, Aranda CJ, Ocón B, Uriarte I, de Medina FS, Martinez-Augustín O, Avila MA, Marín JJG, Romero MR.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2927-2937. doi: 10.1016/j.bbadis.2018.06.003. Epub 2018 Jun 6.

24.

Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.

Lozano E, Briz O, Macias RIR, Serrano MA, Marin JJG, Herraez E.

J Pers Med. 2018 Apr 16;8(2). pii: E14. doi: 10.3390/jpm8020014. Review.

25.

Dysregulation of autophagy in rat liver with mitochondrial DNA depletion induced by the nucleoside analogue zidovudine.

Santos-Llamas A, Monte MJ, Marin JJG, Perez MJ.

Arch Toxicol. 2018 Jun;92(6):2109-2118. doi: 10.1007/s00204-018-2200-5. Epub 2018 Mar 28.

PMID:
29594326
26.

Molecular bases of the poor response of liver cancer to chemotherapy.

Marin JJG, Briz O, Herraez E, Lozano E, Asensio M, Di Giacomo S, Romero MR, Osorio-Padilla LM, Santos-Llamas AI, Serrano MA, Armengol C, Efferth T, Macias RIR.

Clin Res Hepatol Gastroenterol. 2018 Jun;42(3):182-192. doi: 10.1016/j.clinre.2017.12.006. Epub 2018 Mar 12. Review.

PMID:
29544679
27.

Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer.

Verdugo-Sivianes EM, Navas L, Molina-Pinelo S, Ferrer I, Quintanal-Villalonga A, Peinado J, Garcia-Heredia JM, Felipe-Abrio B, Muñoz-Galvan S, Marin JJ, Montuenga L, Paz-Ares L, Carnero A.

Oncotarget. 2017 Oct 26;8(62):105196-105210. doi: 10.18632/oncotarget.22111. eCollection 2017 Dec 1.

28.

Balance study in asymptomatic subjects: Determination of significant variables and reference patterns to improve clinical application.

de la Torre J, Marin J, Marin JJ, Auria JM, Sanchez-Valverde MB.

J Biomech. 2017 Dec 8;65:161-168. doi: 10.1016/j.jbiomech.2017.10.013. Epub 2017 Nov 7.

PMID:
29126606
29.

MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation.

Erice O, Munoz-Garrido P, Vaquero J, Perugorria MJ, Fernandez-Barrena MG, Saez E, Santos-Laso A, Arbelaiz A, Jimenez-Agüero R, Fernandez-Irigoyen J, Santamaria E, Torrano V, Carracedo A, Ananthanarayanan M, Marzioni M, Prieto J, Beuers U, Oude Elferink RP, LaRusso NF, Bujanda L, Marin JJG, Banales JM.

Hepatology. 2018 Apr;67(4):1420-1440. doi: 10.1002/hep.29533. Epub 2018 Feb 21.

30.

Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression.

Erice O, Labiano I, Arbelaiz A, Santos-Laso A, Munoz-Garrido P, Jimenez-Agüero R, Olaizola P, Caro-Maldonado A, Martín-Martín N, Carracedo A, Lozano E, Marin JJ, O'Rourke CJ, Andersen JB, Llop J, Gómez-Vallejo V, Padro D, Martin A, Marzioni M, Adorini L, Trauner M, Bujanda L, Perugorria MJ, Banales JM.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1335-1344. doi: 10.1016/j.bbadis.2017.08.016. Epub 2017 Sep 13.

31.

Octopus: A Design Methodology for Motion Capture Wearables.

Marin J, Blanco T, Marin JJ.

Sensors (Basel). 2017 Aug 15;17(8). pii: E1875. doi: 10.3390/s17081875.

32.

Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland.

Blazquez AMG, Macias RIR, Cives-Losada C, de la Iglesia A, Marin JJG, Monte MJ.

Sci Rep. 2017 Aug 7;7(1):7475. doi: 10.1038/s41598-017-06315-8.

33.

The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma.

Macias RIR, Banales JM, Sangro B, Muntané J, Avila MA, Lozano E, Perugorria MJ, Padillo FJ, Bujanda L, Marin JJG.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1468-1477. doi: 10.1016/j.bbadis.2017.08.002. Epub 2017 Aug 4. Review.

34.

Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver.

Nuñez-Garcia M, Gomez-Santos B, Buqué X, García-Rodriguez JL, Romero MR, Marin JJG, Arteta B, García-Monzón C, Castaño L, Syn WK, Fresnedo O, Aspichueta P.

J Lipid Res. 2017 Sep;58(9):1903-1915. doi: 10.1194/jlr.M078980. Epub 2017 Jul 28.

35.

Chemoresistance and chemosensitization in cholangiocarcinoma.

Marin JJG, Lozano E, Herraez E, Asensio M, Di Giacomo S, Romero MR, Briz O, Serrano MA, Efferth T, Macias RIR.

Biochim Biophys Acta Mol Basis Dis. 2018 Apr;1864(4 Pt B):1444-1453. doi: 10.1016/j.bbadis.2017.06.005. Epub 2017 Jul 7. Review.

36.

Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma.

Arbelaiz A, Azkargorta M, Krawczyk M, Santos-Laso A, Lapitz A, Perugorria MJ, Erice O, Gonzalez E, Jimenez-Agüero R, Lacasta A, Ibarra C, Sanchez-Campos A, Jimeno JP, Lammert F, Milkiewicz P, Marzioni M, Macias RIR, Marin JJG, Patel T, Gores GJ, Martinez I, Elortza F, Falcon-Perez JM, Bujanda L, Banales JM.

Hepatology. 2017 Oct;66(4):1125-1143. doi: 10.1002/hep.29291. Epub 2017 Aug 26.

PMID:
28555885
37.

Relationship between early onset severe intrahepatic cholestasis of pregnancy and higher risk of meconium-stained fluid.

Estiú MC, Frailuna MA, Otero C, Dericco M, Williamson C, Marin JJG, Macias RIR.

PLoS One. 2017 Apr 24;12(4):e0176504. doi: 10.1371/journal.pone.0176504. eCollection 2017.

38.

Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1.

Herraez E, Sanchez-Vicente L, Macias RIR, Briz O, Marin JJG.

Oncotarget. 2017 May 23;8(21):34617-34629. doi: 10.18632/oncotarget.16119.

39.

Bile Acids in Polycystic Liver Diseases: Triggers of Disease Progression and Potential Solution for Treatment.

Perugorria MJ, Labiano I, Esparza-Baquer A, Marzioni M, Marin JJ, Bujanda L, Banales JM.

Dig Dis. 2017;35(3):275-281. doi: 10.1159/000450989. Epub 2017 Mar 1. Review.

PMID:
28249268
40.

SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma.

Merino-Azpitarte M, Lozano E, Perugorria MJ, Esparza-Baquer A, Erice O, Santos-Laso Á, O'Rourke CJ, Andersen JB, Jiménez-Agüero R, Lacasta A, D'Amato M, Briz Ó, Jalan-Sakrikar N, Huebert RC, Thelen KM, Gradilone SA, Aransay AM, Lavín JL, Fernández-Barrena MG, Matheu A, Marzioni M, Gores GJ, Bujanda L, Marin JJG, Banales JM.

J Hepatol. 2017 Jul;67(1):72-83. doi: 10.1016/j.jhep.2017.02.017. Epub 2017 Feb 22.

41.

New Advances in Polycystic Liver Diseases.

Santos-Laso A, Izquierdo-Sánchez L, Lee-Law PY, Perugorria MJ, Marzioni M, Marin JJ, Bujanda L, Banales JM.

Semin Liver Dis. 2017 Feb;37(1):45-55. doi: 10.1055/s-0036-1597817. Epub 2017 Feb 15. Review.

PMID:
28201848
42.

The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma.

Geier A, Macias RI, Bettinger D, Weiss J, Bantel H, Jahn D, Al-Abdulla R, Marin JJ.

Oncotarget. 2017 Feb 28;8(9):15846-15857. doi: 10.18632/oncotarget.15029.

43.

ACOX2 deficiency: An inborn error of bile acid synthesis identified in an adolescent with persistent hypertransaminasemia.

Monte MJ, Alonso-Peña M, Briz O, Herraez E, Berasain C, Argemi J, Prieto J, Marin JJG.

J Hepatol. 2017 Mar;66(3):581-588. doi: 10.1016/j.jhep.2016.11.005. Epub 2016 Nov 21.

PMID:
27884763
44.

Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1α.

Marin JJG, Lozano E, Perez MJ.

Free Radic Biol Med. 2016 Dec;101:71-84. doi: 10.1016/j.freeradbiomed.2016.09.025. Epub 2016 Sep 26.

PMID:
27687210
45.

Pharmacogenomic analyzis of the responsiveness of gastrointestinal tumor cell lines to drug therapy: A transportome approach.

Grañé-Boladeras N, Pérez-Torras S, Lozano JJ, Romero MR, Mazo A, Marín JJG, Pastor-Anglada M.

Pharmacol Res. 2016 Nov;113(Pt A):364-375. doi: 10.1016/j.phrs.2016.09.007. Epub 2016 Sep 9.

PMID:
27620070
46.

Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice.

Nuño-Lámbarri N, Domínguez-Pérez M, Baulies-Domenech A, Monte MJ, Marin JJ, Rosales-Cruz P, Souza V, Miranda RU, Bucio L, Montalvo-Jave EE, Concepción Gutiérrez-Ruiz M, García-Ruiz C, Fernández-Checa JC, Gomez-Quiroz LE.

Oxid Med Cell Longev. 2016;2016:9895176. doi: 10.1155/2016/9895176. Epub 2016 Aug 21.

47.

Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation.

Rau M, Stieger B, Monte MJ, Schmitt J, Jahn D, Frey-Wagner I, Raselli T, Marin JJ, Müllhaupt B, Rogler G, Geier A.

Inflamm Bowel Dis. 2016 Oct;22(10):2382-9. doi: 10.1097/MIB.0000000000000879.

48.

Protective role of biliverdin against bile acid-induced oxidative stress in liver cells.

Gonzalez-Sanchez E, Perez MJ, Nytofte NS, Briz O, Monte MJ, Lozano E, Serrano MA, Marin JJG.

Free Radic Biol Med. 2016 Aug;97:466-477. doi: 10.1016/j.freeradbiomed.2016.06.016. Epub 2016 Jul 5.

PMID:
27387768
49.

Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).

Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D.

Nat Rev Gastroenterol Hepatol. 2016 May;13(5):261-80. doi: 10.1038/nrgastro.2016.51. Epub 2016 Apr 20.

50.

Biodetection of potential genotoxic pollutants entering the human food chain through ashes used in livestock diets.

Sanchez-Vicente L, Herraez E, Briz O, Nogales R, Molina-Alcaide E, Marin JJ.

Food Chem. 2016 Aug 15;205:81-8. doi: 10.1016/j.foodchem.2016.02.160. Epub 2016 Mar 3.

PMID:
27006217

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