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Items: 1 to 50 of 139

1.

Displaced by Deceivers: Prevention of Biosensor Cross-Talk Is Pivotal for Successful Biosensor-Based High-Throughput Screening Campaigns.

Flachbart LK, Sokolowsky S, Marienhagen J.

ACS Synth Biol. 2019 Aug 16;8(8):1847-1857. doi: 10.1021/acssynbio.9b00149. Epub 2019 Jul 23.

2.

Alone at last! - Heterologous expression of a single gene is sufficient for establishing the five-step Weimberg pathway in Corynebacterium glutamicum.

Brüsseler C, Späth A, Sokolowsky S, Marienhagen J.

Metab Eng Commun. 2019 Apr 10;9:e00090. doi: 10.1016/j.mec.2019.e00090. eCollection 2019 Dec.

3.

Tailoring Corynebacterium glutamicum towards increased malonyl-CoA availability for efficient synthesis of the plant pentaketide noreugenin.

Milke L, Kallscheuer N, Kappelmann J, Marienhagen J.

Microb Cell Fact. 2019 Apr 11;18(1):71. doi: 10.1186/s12934-019-1117-x.

4.

Modulation of the central carbon metabolism of Corynebacterium glutamicum improves malonyl-CoA availability and increases plant polyphenol synthesis.

Milke L, Ferreira P, Kallscheuer N, Braga A, Vogt M, Kappelmann J, Oliveira J, Silva AR, Rocha I, Bott M, Noack S, Faria N, Marienhagen J.

Biotechnol Bioeng. 2019 Jun;116(6):1380-1391. doi: 10.1002/bit.26939. Epub 2019 Feb 28.

PMID:
30684355
5.

Six versus eight doses of rituximab in patients with aggressive B cell lymphoma receiving six cycles of CHOP: results from the "Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin Lymphomas" (PETAL) trial.

Hüttmann A, Rekowski J, Müller SP, Hertenstein B, Franzius C, Mesters R, Weckesser M, Kroschinsky F, Kotzerke J, Ganser A, Bengel FM, La Rosée P, Freesmeyer M, Höffkes HG, Hertel A, Behringer D, Prange-Krex G, Griesshammer M, Holzinger J, Wilop S, Krohn T, Raghavachar A, Maschmeyer G, Brink I, Schroers R, Gaska T, Bernhard H, Giagounidis A, Schütte J, Dienst A, Hautzel H, Naumann R, Klein A, Hahn D, Pöpperl G, Grube M, Marienhagen J, Schwarzer A, Kurch L, Höhler T, Steiniger H, Nückel H, Südhoff T, Römer W, Brinkmann M, Ose C, Alashkar F, Schmitz C, Dürig J, Hoelzer D, Jöckel KH, Klapper W, Dührsen U.

Ann Hematol. 2019 Apr;98(4):897-907. doi: 10.1007/s00277-018-3578-0. Epub 2019 Jan 4.

PMID:
30610279
6.

Microbial Production of Natural and Unnatural Monolignols with Escherichia coli.

Aschenbrenner J, Marx P, Pietruszka J, Marienhagen J.

Chembiochem. 2019 Apr 1;20(7):949-954. doi: 10.1002/cbic.201800673. Epub 2019 Feb 19.

PMID:
30537293
7.

Identification and Microbial Production of the Raspberry Phenol Salidroside that Is Active against Huntington's Disease.

Kallscheuer N, Menezes R, Foito A, da Silva MH, Braga A, Dekker W, Sevillano DM, Rosado-Ramos R, Jardim C, Oliveira J, Ferreira P, Rocha I, Silva AR, Sousa M, Allwood JW, Bott M, Faria N, Stewart D, Ottens M, Naesby M, Nunes Dos Santos C, Marienhagen J.

Plant Physiol. 2019 Mar;179(3):969-985. doi: 10.1104/pp.18.01074. Epub 2018 Nov 5.

PMID:
30397021
8.

[Development of a national competency-based learning objective catalogue for undergraduate medical education in Germany].

Marienhagen J, Brenner W, Buck A, Franzius C, Freudenberg LS, Gotthardt M, Lindner O, Mottaghy FM, Hellwig D.

Nuklearmedizin. 2018 Aug;57(4):137-145. doi: 10.3413/Nukmed-0969-18-03. Epub 2018 Aug 20. German.

PMID:
30125926
9.

Production of plant metabolites with applications in the food industry using engineered microorganisms.

Kallscheuer N, Classen T, Drepper T, Marienhagen J.

Curr Opin Biotechnol. 2019 Apr;56:7-17. doi: 10.1016/j.copbio.2018.07.008. Epub 2018 Aug 13. Review.

PMID:
30114548
10.

Production of d-xylonic acid using a non-recombinant Corynebacterium glutamicum strain.

Tenhaef N, Brüsseler C, Radek A, Hilmes R, Unrean P, Marienhagen J, Noack S.

Bioresour Technol. 2018 Nov;268:332-339. doi: 10.1016/j.biortech.2018.07.127. Epub 2018 Jul 26.

PMID:
30092487
11.

Corynebacterium glutamicum as platform for the production of hydroxybenzoic acids.

Kallscheuer N, Marienhagen J.

Microb Cell Fact. 2018 May 12;17(1):70. doi: 10.1186/s12934-018-0923-x.

12.

Visualizing the Bayesian 2-test case: The effect of tree diagrams on medical decision making.

Binder K, Krauss S, Bruckmaier G, Marienhagen J.

PLoS One. 2018 Mar 27;13(3):e0195029. doi: 10.1371/journal.pone.0195029. eCollection 2018.

13.

Production of plant-derived polyphenols in microorganisms: current state and perspectives.

Milke L, Aschenbrenner J, Marienhagen J, Kallscheuer N.

Appl Microbiol Biotechnol. 2018 Feb;102(4):1575-1585. doi: 10.1007/s00253-018-8747-5. Epub 2018 Jan 16. Review.

PMID:
29340710
14.

OptPipe - a pipeline for optimizing metabolic engineering targets.

Hartmann A, Vila-Santa A, Kallscheuer N, Vogt M, Julien-Laferrière A, Sagot MF, Marienhagen J, Vinga S.

BMC Syst Biol. 2017 Dec 21;11(1):143. doi: 10.1186/s12918-017-0515-0.

15.

The myo-inositol/proton symporter IolT1 contributes to d-xylose uptake in Corynebacterium glutamicum.

Brüsseler C, Radek A, Tenhaef N, Krumbach K, Noack S, Marienhagen J.

Bioresour Technol. 2018 Feb;249:953-961. doi: 10.1016/j.biortech.2017.10.098. Epub 2017 Nov 1.

PMID:
29145122
16.

Impact of the cultivation strategy on resveratrol production from glucose in engineered Corynebacterium glutamicum.

Braga A, Oliveira J, Silva R, Ferreira P, Rocha I, Kallscheuer N, Marienhagen J, Faria N.

J Biotechnol. 2018 Jan 10;265:70-75. doi: 10.1016/j.jbiotec.2017.11.006. Epub 2017 Nov 12.

PMID:
29141192
17.

Miniaturized and automated adaptive laboratory evolution: Evolving Corynebacterium glutamicum towards an improved d-xylose utilization.

Radek A, Tenhaef N, Müller MF, Brüsseler C, Wiechert W, Marienhagen J, Polen T, Noack S.

Bioresour Technol. 2017 Dec;245(Pt B):1377-1385. doi: 10.1016/j.biortech.2017.05.055. Epub 2017 May 12.

PMID:
28552568
18.

Reversal of β-oxidative pathways for the microbial production of chemicals and polymer building blocks.

Kallscheuer N, Polen T, Bott M, Marienhagen J.

Metab Eng. 2017 Jul;42:33-42. doi: 10.1016/j.ymben.2017.05.004. Epub 2017 May 23. Review.

PMID:
28550000
19.

Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production.

Siedler S, Khatri NK, Zsohár A, Kjærbølling I, Vogt M, Hammar P, Nielsen CF, Marienhagen J, Sommer MOA, Joensson HN.

ACS Synth Biol. 2017 Oct 20;6(10):1860-1869. doi: 10.1021/acssynbio.7b00009. Epub 2017 Jun 21.

PMID:
28532147
20.

[Nuclear Medicine in Germany. Updated key data and trends from official statistics].

Hellwig D, Marienhagen J, Menhart K, Grosse J.

Nuklearmedizin. 2017 Apr 5;56(2):55-68. doi: 10.3413/Nukmed-0880-17-02. Epub 2017 Mar 7. German.

PMID:
28265641
21.

Functional expression of plant-derived O-methyltransferase, flavanone 3-hydroxylase, and flavonol synthase in Corynebacterium glutamicum for production of pterostilbene, kaempferol, and quercetin.

Kallscheuer N, Vogt M, Bott M, Marienhagen J.

J Biotechnol. 2017 Sep 20;258:190-196. doi: 10.1016/j.jbiotec.2017.01.006. Epub 2017 Jan 28.

PMID:
28143765
22.

Octreotide LAR and Prednisone as Neoadjuvant Treatment in Patients with Primary or Locally Recurrent Unresectable Thymic Tumors: A Phase II Study.

Kirzinger L, Boy S, Marienhagen J, Schuierer G, Neu R, Ried M, Hofmann HS, Wiebe K, Ströbel P, May C, Kleylein-Sohn J, Baierlein C, Bogdahn U, Marx A, Schalke B.

PLoS One. 2016 Dec 16;11(12):e0168215. doi: 10.1371/journal.pone.0168215. eCollection 2016.

23.

A Novel Synthetic Pathway Enables Microbial Production of Polyphenols Independent from the Endogenous Aromatic Amino Acid Metabolism.

Kallscheuer N, Vogt M, Marienhagen J.

ACS Synth Biol. 2017 Mar 17;6(3):410-415. doi: 10.1021/acssynbio.6b00291. Epub 2016 Dec 14.

PMID:
27936616
24.

Construction of a Corynebacterium glutamicum platform strain for the production of stilbenes and (2S)-flavanones.

Kallscheuer N, Vogt M, Stenzel A, Gätgens J, Bott M, Marienhagen J.

Metab Eng. 2016 Nov;38:47-55. doi: 10.1016/j.ymben.2016.06.003. Epub 2016 Jun 8.

PMID:
27288926
25.

Mutations in MurE, the essential UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase of Corynebacterium glutamicum: effect on L-lysine formation and analysis of systemic consequences.

Hochheim J, Kranz A, Krumbach K, Sokolowsky S, Eggeling L, Noack S, Bocola M, Bott M, Marienhagen J.

Biotechnol Lett. 2017 Feb;39(2):283-288. doi: 10.1007/s10529-016-2243-8. Epub 2016 Oct 25.

PMID:
27783176
26.

Production of 2-methyl-1-butanol and 3-methyl-1-butanol in engineered Corynebacterium glutamicum.

Vogt M, Brüsseler C, Ooyen JV, Bott M, Marienhagen J.

Metab Eng. 2016 Nov;38:436-445. doi: 10.1016/j.ymben.2016.10.007. Epub 2016 Oct 14.

PMID:
27746323
27.

Formation of xylitol and xylitol-5-phosphate and its impact on growth of d-xylose-utilizing Corynebacterium glutamicum strains.

Radek A, Müller MF, Gätgens J, Eggeling L, Krumbach K, Marienhagen J, Noack S.

J Biotechnol. 2016 Aug 10;231:160-166. doi: 10.1016/j.jbiotec.2016.06.009. Epub 2016 Jun 11.

PMID:
27297548
28.

Identification of the phd gene cluster responsible for phenylpropanoid utilization in Corynebacterium glutamicum.

Kallscheuer N, Vogt M, Kappelmann J, Krumbach K, Noack S, Bott M, Marienhagen J.

Appl Microbiol Biotechnol. 2016 Feb;100(4):1871-81. doi: 10.1007/s00253-015-7165-1. Epub 2015 Nov 26.

PMID:
26610800
29.

Combinatorial optimization of synthetic operons for the microbial production of p-coumaryl alcohol with Escherichia coli.

van Summeren-Wesenhagen PV, Voges R, Dennig A, Sokolowsky S, Noack S, Schwaneberg U, Marienhagen J.

Microb Cell Fact. 2015 Jun 11;14:79. doi: 10.1186/s12934-015-0274-9.

30.

Quality management of eLearning for medical education: current situation and outlook.

Abrusch J, Marienhagen J, Böckers A, Gerhardt-Szép S.

GMS Z Med Ausbild. 2015 May 13;32(2):Doc20. doi: 10.3205/zma000962. eCollection 2015.

31.

Metabolic engineering of Corynebacterium glutamicum for methanol metabolism.

Witthoff S, Schmitz K, Niedenführ S, Nöh K, Noack S, Bott M, Marienhagen J.

Appl Environ Microbiol. 2015 Mar;81(6):2215-25. doi: 10.1128/AEM.03110-14. Epub 2015 Jan 16.

32.

Novel screening methods--biosensors.

Eggeling L, Bott M, Marienhagen J.

Curr Opin Biotechnol. 2015 Dec;35:30-6. doi: 10.1016/j.copbio.2014.12.021. Epub 2015 Jan 9. Review.

PMID:
25578902
33.

Metabolic engineering of Escherichia coli for the synthesis of the plant polyphenol pinosylvin.

van Summeren-Wesenhagen PV, Marienhagen J.

Appl Environ Microbiol. 2015 Feb;81(3):840-9. doi: 10.1128/AEM.02966-14. Epub 2014 Nov 14.

34.

Engineering of Corynebacterium glutamicum for minimized carbon loss during utilization of D-xylose containing substrates.

Radek A, Krumbach K, Gätgens J, Wendisch VF, Wiechert W, Bott M, Noack S, Marienhagen J.

J Biotechnol. 2014 Dec 20;192 Pt A:156-60. doi: 10.1016/j.jbiotec.2014.09.026. Epub 2014 Oct 7.

PMID:
25304460
35.

OmniChange: simultaneous site saturation of up to five codons.

Dennig A, Marienhagen J, Ruff AJ, Schwaneberg U.

Methods Mol Biol. 2014;1179:139-49. doi: 10.1007/978-1-4939-1053-3_9.

PMID:
25055775
36.

Editorial overview: Food biotechnology.

Koffas MA, Marienhagen J.

Curr Opin Biotechnol. 2014 Apr;26:v-vii. doi: 10.1016/j.copbio.2014.02.005. Epub 2014 Mar 1. No abstract available.

PMID:
24594282
37.

The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron-sulfur cluster biogenesis and oxidative stress defence.

Rybniker J, Pojer F, Marienhagen J, Kolly GS, Chen JM, van Gumpel E, Hartmann P, Cole ST.

Biochem J. 2014 May 1;459(3):467-78. doi: 10.1042/BJ20130732.

PMID:
24548275
38.

Looking for the pick of the bunch: high-throughput screening of producing microorganisms with biosensors.

Schallmey M, Frunzke J, Eggeling L, Marienhagen J.

Curr Opin Biotechnol. 2014 Apr;26:148-54. doi: 10.1016/j.copbio.2014.01.005. Epub 2014 Jan 28. Review.

39.

Benzothiazinones mediate killing of Corynebacterineae by blocking decaprenyl phosphate recycling involved in cell wall biosynthesis.

Grover S, Alderwick LJ, Mishra AK, Krumbach K, Marienhagen J, Eggeling L, Bhatt A, Besra GS.

J Biol Chem. 2014 Feb 28;289(9):6177-87. doi: 10.1074/jbc.M113.522623. Epub 2014 Jan 20.

40.

C1 metabolism in Corynebacterium glutamicum: an endogenous pathway for oxidation of methanol to carbon dioxide.

Witthoff S, Mühlroth A, Marienhagen J, Bott M.

Appl Environ Microbiol. 2013 Nov;79(22):6974-83. doi: 10.1128/AEM.02705-13. Epub 2013 Sep 6.

41.

Putting bugs to the blush: metabolic engineering for phenylpropanoid-derived products in microorganisms.

van Summeren-Wesenhagen PV, Marienhagen J.

Bioengineered. 2013 Nov-Dec;4(6):355-62. doi: 10.4161/bioe.23885. Epub 2013 Nov 18.

42.

Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation.

Binder S, Siedler S, Marienhagen J, Bott M, Eggeling L.

Nucleic Acids Res. 2013 Jul;41(12):6360-9. doi: 10.1093/nar/gkt312. Epub 2013 Apr 28.

43.

Direct oxidation of cycloalkanes to cycloalkanones with oxygen in water.

Staudt S, Burda E, Giese C, Müller CA, Marienhagen J, Schwaneberg U, Hummel W, Drauz K, Gröger H.

Angew Chem Int Ed Engl. 2013 Feb 18;52(8):2359-63. doi: 10.1002/anie.201204464. Epub 2013 Jan 21. No abstract available.

PMID:
23339093
44.

MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes.

Braun A, Halwachs B, Geier M, Weinhandl K, Guggemos M, Marienhagen J, Ruff AJ, Schwaneberg U, Rabin V, Torres Pazmiño DE, Thallinger GG, Glieder A.

Database (Oxford). 2012 Jun 21;2012:bas028. doi: 10.1093/database/bas028. Print 2012.

45.

Metabolic engineering of microorganisms for the synthesis of plant natural products.

Marienhagen J, Bott M.

J Biotechnol. 2013 Jan 20;163(2):166-78. doi: 10.1016/j.jbiotec.2012.06.001. Epub 2012 Jun 9. Review.

PMID:
22687248
46.

Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease.

Leypoldt F, Buchert R, Kleiter I, Marienhagen J, Gelderblom M, Magnus T, Dalmau J, Gerloff C, Lewerenz J.

J Neurol Neurosurg Psychiatry. 2012 Jul;83(7):681-6. doi: 10.1136/jnnp-2011-301969. Epub 2012 May 7.

47.

Phosphorothioate-based DNA recombination: an enzyme-free method for the combinatorial assembly of multiple DNA fragments.

Marienhagen J, Dennig A, Schwaneberg U.

Biotechniques. 2012 May 1;52(5). doi: 10.2144/000113865.

48.

Biocatalytic hydroxylation of n-butane with in situ cofactor regeneration at low temperature and under normal pressure.

Staudt S, Müller CA, Marienhagen J, Böing C, Buchholz S, Schwaneberg U, Gröger H.

Beilstein J Org Chem. 2012;8:186-91. doi: 10.3762/bjoc.8.20. Epub 2012 Feb 2.

49.

OmniChange: the sequence independent method for simultaneous site-saturation of five codons.

Dennig A, Shivange AV, Marienhagen J, Schwaneberg U.

PLoS One. 2011;6(10):e26222. doi: 10.1371/journal.pone.0026222. Epub 2011 Oct 19.

50.

Neural correlates of tinnitus duration and distress: a positron emission tomography study.

Schecklmann M, Landgrebe M, Poeppl TB, Kreuzer P, Männer P, Marienhagen J, Wack DS, Kleinjung T, Hajak G, Langguth B.

Hum Brain Mapp. 2013 Jan;34(1):233-40. doi: 10.1002/hbm.21426. Epub 2011 Oct 22.

PMID:
22021023

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