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Items: 48


Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells.

Wilkat M, Bast H, Drees R, Dünser J, Mahr A, Azoitei N, Marienfeld R, Frank F, Brhel M, Ushmorov A, Greve J, Goldberg-Bockhorn E, Theodoraki MN, Doescher J, Laban S, Schuler PJ, Hoffmann TK, Brunner C.

Int J Cancer. 2019 Dec 17. doi: 10.1002/ijc.32835. [Epub ahead of print]


Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information.

Ettrich TJ, Schwerdel D, Dolnik A, Beuter F, Blätte TJ, Schmidt SA, Stanescu-Siegmund N, Steinacker J, Marienfeld R, Kleger A, Bullinger L, Seufferlein T, Berger AW.

Sci Rep. 2019 Sep 13;9(1):13261. doi: 10.1038/s41598-019-49860-0.


Antibody Responses to Cancer Antigens Identify Patients with a Poor Prognosis among HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Patients.

Laban S, Gangkofner DS, Holzinger D, Schroeder L, Eichmüller SB, Zörnig I, Jäger D, Wichmann G, Dietz A, Broglie MA, Herold-Mende CC, Dyckhoff G, Boscolo-Rizzo P, Ezić J, Marienfeld R, Möller P, Kraus JM, Völkel G, Kestler HA, Brunner C, Schuler PJ, Wigand MC, Theodoraki MN, Doescher J, Hoffmann TK, Pawlita M, Waterboer T, Butt J.

Clin Cancer Res. 2019 Dec 15;25(24):7405-7412. doi: 10.1158/1078-0432.CCR-19-1490. Epub 2019 Aug 23.


Patterns of antibody responses to nonviral cancer antigens in head and neck squamous cell carcinoma patients differ by human papillomavirus status.

Gangkofner DS, Holzinger D, Schroeder L, Eichmüller SB, Zörnig I, Jäger D, Wichmann G, Dietz A, Broglie MA, Herold-Mende C, Dyckhoff G, Boscolo-Rizzo P, Ezic J, Marienfeld RB, Möller P, Völkel G, Kraus JM, Kestler HA, Brunner C, Schuler PJ, Wigand M, Theodoraki MN, Doescher J, Hoffmann TK, Pawlita M, Butt J, Waterboer T, Laban S.

Int J Cancer. 2019 Dec 15;145(12):3436-3444. doi: 10.1002/ijc.32623. Epub 2019 Aug 26.


Characterization of Three Novel H3F3A-mutated Giant Cell Tumor Cell Lines and Targeting of Their Wee1 Pathway.

Lübbehüsen C, Lüke J, Seeling C, Mellert K, Marienfeld R, von Baer A, Schultheiss M, Möller P, Barth TFE.

Sci Rep. 2019 Apr 23;9(1):6458. doi: 10.1038/s41598-019-42611-1.


Variant classification in precision oncology.

Leichsenring J, Horak P, Kreutzfeldt S, Heining C, Christopoulos P, Volckmar AL, Neumann O, Kirchner M, Ploeger C, Budczies J, Heilig CE, Hutter B, Fröhlich M, Uhrig S, Kazdal D, Allgäuer M, Harms A, Rempel E, Lehmann U, Thomas M, Pfarr N, Azoitei N, Bonzheim I, Marienfeld R, Möller P, Werner M, Fend F, Boerries M, von Bubnoff N, Lassmann S, Longerich T, Bitzer M, Seufferlein T, Malek N, Weichert W, Schirmacher P, Penzel R, Endris V, Brors B, Klauschen F, Glimm H, Fröhling S, Stenzinger A.

Int J Cancer. 2019 Dec 1;145(11):2996-3010. doi: 10.1002/ijc.32358. Epub 2019 May 21.


Analysis of the CDK4/6 Cell Cycle Pathway in Leiomyosarcomas as a Potential Target for Inhibition by Palbociclib.

Böhm MJ, Marienfeld R, Jäger D, Mellert K, von Witzleben A, Brüderlein S, Wittau M, von Baer A, Schultheiss M, Mayer-Steinacker R, Rücker FG, Möller P, Bullinger L, Barth TFE.

Sarcoma. 2019 Jan 21;2019:3914232. doi: 10.1155/2019/3914232. eCollection 2019.


[H3F3A mutated multicentric giant cell tumor of bone : A very rare primary bone disease].

Giesche JP, von Baer A, Breining T, Marienfeld R, Mellert K, Lüke J, Schultheiss M, Möller P, Barth TFE.

Pathologe. 2018 Sep;39(5):451-456. doi: 10.1007/s00292-018-0460-8. German.


Targeted deep sequencing of circulating tumor DNA in metastatic pancreatic cancer.

Berger AW, Schwerdel D, Ettrich TJ, Hann A, Schmidt SA, Kleger A, Marienfeld R, Seufferlein T.

Oncotarget. 2017 Dec 16;9(2):2076-2085. doi: 10.18632/oncotarget.23330. eCollection 2018 Jan 5.


GSK3β modulates NF-κB activation and RelB degradation through site-specific phosphorylation of BCL10.

Abd-Ellah A, Voogdt C, Krappmann D, Möller P, Marienfeld RB.

Sci Rep. 2018 Jan 22;8(1):1352. doi: 10.1038/s41598-018-19822-z.


Trail (TNF-related apoptosis-inducing ligand) induces an inflammatory response in human adipocytes.

Zoller V, Funcke JB, Roos J, Dahlhaus M, Abd El Hay M, Holzmann K, Marienfeld R, Kietzmann T, Debatin KM, Wabitsch M, Fischer-Posovszky P.

Sci Rep. 2017 Jul 18;7(1):5691. doi: 10.1038/s41598-017-05932-7.


Treatment monitoring in metastatic colorectal cancer patients by quantification and KRAS genotyping of circulating cell-free DNA.

Berger AW, Schwerdel D, Welz H, Marienfeld R, Schmidt SA, Kleger A, Ettrich TJ, Seufferlein T.

PLoS One. 2017 Mar 22;12(3):e0174308. doi: 10.1371/journal.pone.0174308. eCollection 2017.


H3F3A mutation in giant cell tumour of the bone is detected by immunohistochemistry using a monoclonal antibody against the G34W mutated site of the histone H3.3 variant.

Lüke J, von Baer A, Schreiber J, Lübbehüsen C, Breining T, Mellert K, Marienfeld R, Schultheiss M, Möller P, Barth TFE.

Histopathology. 2017 Jul;71(1):125-133. doi: 10.1111/his.13190. Epub 2017 Apr 10.


A novel PTPN1 splice variant upregulates JAK/STAT activity in classical Hodgkin lymphoma cells.

Zahn M, Marienfeld R, Melzner I, Heinrich J, Renner B, Wegener S, Mießner A, Barth TF, Dorsch K, Brüderlein S, Möller P.

Blood. 2017 Mar 16;129(11):1480-1490. doi: 10.1182/blood-2016-06-720516. Epub 2017 Jan 12.


Automation of DNA and miRNA co-extraction for miRNA-based identification of human body fluids and tissues.

Kulstein G, Marienfeld R, Miltner E, Wiegand P.

Electrophoresis. 2016 Oct;37(21):2742-2750. doi: 10.1002/elps.201600365. Epub 2016 Sep 19.


Silencer of Cytokine Signaling 1 gene is not hypermethylated in diffuse large B-cell lymphoma.

Lennerz JK, Weissinger SE, Gerstenmaier U, Marienfeld R, Möller P; network project Molecular Mechanisms in Malignant Lymphomas.

Br J Haematol. 2017 Oct;179(1):158-160. doi: 10.1111/bjh.14188. Epub 2016 Jun 15. No abstract available.


Preclinical Characterization of Novel Chordoma Cell Systems and Their Targeting by Pharmocological Inhibitors of the CDK4/6 Cell-Cycle Pathway.

von Witzleben A, Goerttler LT, Marienfeld R, Barth H, Lechel A, Mellert K, Böhm M, Kornmann M, Mayer-Steinacker R, von Baer A, Schultheiss M, Flanagan AM, Möller P, Brüderlein S, Barth TF.

Cancer Res. 2015 Sep 15;75(18):3823-31. doi: 10.1158/0008-5472.CAN-14-3270. Epub 2015 Jul 16.


Validation of a Manual Protocol for BRAF V600E Mutation-specific Immunohistochemistry.

Dinges HC, Capper D, Ritz O, Brüderlein S, Marienfeld R, von Deimling A, Möller P, Lennerz JK.

Appl Immunohistochem Mol Morphol. 2015 May-Jun;23(5):382-8. doi: 10.1097/PAI.0000000000000092.


NF-κB factors control the induction of NFATc1 in B lymphocytes.

Muhammad K, Alrefai H, Marienfeld R, Pham DA, Murti K, Patra AK, Avots A, Bukur V, Sahin U, Kondo E, Klein-Hessling S, Serfling E.

Eur J Immunol. 2014 Nov;44(11):3392-402. doi: 10.1002/eji.201444756. Epub 2014 Sep 26.


KIT mutations in primary mediastinal B-cell lymphoma.

Nagel PD, Stenzinger A, Feld FM, Herrmann MD, Brüderlein S, Barth TF, Marienfeld R, Endris V, Weichert W, Debatin KM, Westhoff MA, Lessel D, Möller P, Lennerz JK.

Blood Cancer J. 2014 Aug 22;4:e241. doi: 10.1038/bcj.2014.61. No abstract available.


SUMOylation attenuates the transcriptional activity of the NF-κB subunit RelB.

Leidner J, Voogdt C, Niedenthal R, Möller P, Marienfeld U, Marienfeld RB.

J Cell Biochem. 2014 Aug;115(8):1430-40. doi: 10.1002/jcb.24794.


STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL).

Ritz O, Rommel K, Dorsch K, Kelsch E, Melzner J, Buck M, Leroy K, Papadopoulou V, Wagner S, Marienfeld R, Brüderlein S, Lennerz JK, Möller P.

Oncotarget. 2013 Jul;4(7):1093-102.


FTO deficiency induces UCP-1 expression and mitochondrial uncoupling in adipocytes.

Tews D, Fischer-Posovszky P, Fromme T, Klingenspor M, Fischer J, Rüther U, Marienfeld R, Barth TF, Möller P, Debatin KM, Wabitsch M.

Endocrinology. 2013 Sep;154(9):3141-51. doi: 10.1210/en.2012-1873. Epub 2013 Jun 10.


Octamer-dependent transcription in T cells is mediated by NFAT and NF-κB.

Mueller K, Quandt J, Marienfeld RB, Weihrich P, Fiedler K, Claussnitzer M, Laumen H, Vaeth M, Berberich-Siebelt F, Serfling E, Wirth T, Brunner C.

Nucleic Acids Res. 2013 Feb 1;41(4):2138-54. doi: 10.1093/nar/gks1349. Epub 2013 Jan 4.


IκB kinases modulate the activity of the androgen receptor in prostate carcinoma cell lines.

Jain G, Voogdt C, Tobias A, Spindler KD, Möller P, Cronauer MV, Marienfeld RB.

Neoplasia. 2012 Mar;14(3):178-89.


Pyrosequencing of BRAF V600E in routine samples of hairy cell leukaemia identifies CD5+ variant hairy cell leukaemia that lacks V600E.

Lennerz JK, Klaus BM, Marienfeld RB, Möller P.

Br J Haematol. 2012 Apr;157(2):267-9. doi: 10.1111/j.1365-2141.2011.08963.x. Epub 2011 Dec 7. No abstract available.


NF-κB signaling in prostate cancer: a promising therapeutic target?

Jain G, Cronauer MV, Schrader M, Möller P, Marienfeld RB.

World J Urol. 2012 Jun;30(3):303-10. doi: 10.1007/s00345-011-0792-y. Epub 2011 Nov 16. Review.


The Ca2+-dependent phosphatase calcineurin controls the formation of the Carma1-Bcl10-Malt1 complex during T cell receptor-induced NF-kappaB activation.

Palkowitsch L, Marienfeld U, Brunner C, Eitelhuber A, Krappmann D, Marienfeld RB.

J Biol Chem. 2011 Mar 4;286(9):7522-34. doi: 10.1074/jbc.M110.155895. Epub 2011 Jan 3.


Exogenous CNTF stimulates axon regeneration of retinal ganglion cells partially via endogenous CNTF.

Müller A, Hauk TG, Leibinger M, Marienfeld R, Fischer D.

Mol Cell Neurosci. 2009 Jun;41(2):233-46. doi: 10.1016/j.mcn.2009.03.002. Epub 2009 Mar 28.


Identification of lysine residues critical for the transcriptional activity and polyubiquitination of the NF-kappaB family member RelB.

Leidner J, Palkowitsch L, Marienfeld U, Fischer D, Marienfeld R.

Biochem J. 2008 Nov 15;416(1):117-27. doi: 10.1042/BJ20080432.


Sustained JNK activation in response to tumor necrosis factor is mediated by caspases in a cell type-specific manner.

Wicovsky A, Müller N, Daryab N, Marienfeld R, Kneitz C, Kavuri S, Leverkus M, Baumann B, Wajant H.

J Biol Chem. 2007 Jan 26;282(4):2174-83. Epub 2006 Nov 22.


Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity.

Marienfeld RB, Palkowitsch L, Ghosh S.

Mol Cell Biol. 2006 Dec;26(24):9209-19. Epub 2006 Sep 25.


Yersinia enterocolitica leads to transient induction of TNF-alpha and activates NF-kappaB in synovial fibroblasts.

Meyer-Bahlburg A, Greil S, Kruse N, Marienfeld R, Serfling E, Huppertz HI.

Clin Exp Rheumatol. 2004 May-Jun;22(3):278-84.


Critical role of RelB serine 368 for dimerization and p100 stabilization.

Maier HJ, Marienfeld R, Wirth T, Baumann B.

J Biol Chem. 2003 Oct 3;278(40):39242-50. Epub 2003 Jul 21.


RelB forms transcriptionally inactive complexes with RelA/p65.

Marienfeld R, May MJ, Berberich I, Serfling E, Ghosh S, Neumann M.

J Biol Chem. 2003 May 30;278(22):19852-60. Epub 2003 Mar 25.


Characterization of the Ikappa B-kinase NEMO binding domain.

May MJ, Marienfeld RB, Ghosh S.

J Biol Chem. 2002 Nov 29;277(48):45992-6000. Epub 2002 Sep 19.


Signal-specific and phosphorylation-dependent RelB degradation: a potential mechanism of NF-kappaB control.

Marienfeld R, Berberich-Siebelt F, Berberich I, Denk A, Serfling E, Neumann M.

Oncogene. 2001 Dec 6;20(56):8142-7.


Induction of nuclear factor-kappa B during primary B cell differentiation.

Kistler B, Rolink A, Marienfeld R, Neumann M, Wirth T.

J Immunol. 1998 Mar 1;160(5):2308-17.


Rel/NF-kappa B transcription factors and cancer.

Neumann M, Marienfeld R, Serfling E.

Int J Oncol. 1997 Dec;11(6):1335-47.


Cyclosporin A interferes with the inducible degradation of NF-kappa B inhibitors, but not with the processing of p105/NF-kappa B1 in T cells.

Marienfeld R, Neumann M, Chuvpilo S, Escher C, Kneitz B, Avots A, Schimpl A, Serfling E.

Eur J Immunol. 1997 Jul;27(7):1601-9.


Cloning of chicken interferon regulatory factor-2 (IRF-2) cDNA: expression and mapping of the IRF-2 gene.

Marienfeld R, Nanda I, Zöller B, Schmid M, Rebbert M, Jungwirth C.

J Interferon Cytokine Res. 1997 Apr;17(4):219-27.


Adult respiratory distress syndrome secondary to tularemia pneumonia.

Sunderrajan EV, Hutton J, Marienfeld RD.

Arch Intern Med. 1985 Aug;145(8):1435-7.


Six-year documentation of the easy grader in the medical clerkship setting.

Marienfeld RD, Reid JC.

J Med Educ. 1984 Jul;59(7):589-91. No abstract available.


The dean's letter: the preclinical years neglected.

Marienfeld RD, Mengel CE.

J Med Educ. 1981 Apr;56(4):354-6. No abstract available.


Subjective vs. objective evaluation of clinical clerks.

Marienfeld RD, Reid JC.

N Engl J Med. 1980 May 1;302(18):1036-7. No abstract available.


Comparison of initial house staff goals with eventual career plans in internal medicine.

Marienfeld RD.

J Med Educ. 1977 Oct;52(10):853-5. No abstract available.


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