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A simple ex vivo model of human renal allograft preservation using the gonadal vein.

Ries WP, Marie Y, Patel K, Turnbull C, Smith TB, Jamil N, Caldwell H, Telfer R, Neil D, Nath J, Inston NG.

Ann R Coll Surg Engl. 2019 Sep 11:1-8. doi: 10.1308/rcsann.2019.0107. [Epub ahead of print]


Juvenile myoclonic epilepsy phenotype in a family with Unverricht-Lundborg disease.

Berrechid AG, Bendjebara M, Bouteiller D, Nasri A, Peuvion JN, Marie Y, Baulac S, Mrabet S, Ribierre T, Cazeneuve C, Imenkacem, Leguern E, Gouider R.

Epileptic Disord. 2019 Aug 1;21(4):359-365. doi: 10.1684/epd.2019.1078.


Molecular Profiling Reclassifies Adult Astroblastoma into Known and Clinically Distinct Tumor Entities with Frequent Mitogen-Activated Protein Kinase Pathway Alterations.

Boisseau W, Euskirchen P, Mokhtari K, Dehais C, Touat M, Hoang-Xuan K, Sanson M, Capelle L, Nouet A, Karachi C, Bielle F, Guégan J, Marie Y, Martin-Duverneuil N, Taillandier L, Rousseau A, Delattre JY, Idbaih A.

Oncologist. 2019 Jul 25. pii: theoncologist.2019-0223. doi: 10.1634/theoncologist.2019-0223. [Epub ahead of print]


Treatment of transplant renal artery pseudoaneurysm using expandable hydrogel coils: A case report and review of literature.

Marie Y, Kumar A, Hinchliffe S, Curran S, Brown P, Turner D, Shrestha B.

World J Transplant. 2018 Oct 22;8(6):232-236. doi: 10.5500/wjt.v8.i6.232.


Posterior fossa recurrence of WHO grade II and III supratentorial gliomas.

Terziev R, Petrirena G, Marie Y, Mueller WC, Bielle F, Delattre JY.

Rev Neurol (Paris). 2018 Dec;174(10):705-710. doi: 10.1016/j.neurol.2017.10.018. Epub 2018 Oct 9.


Machine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma.

Rosenberg S, Ducray F, Alentorn A, Dehais C, Elarouci N, Kamoun A, Marie Y, Tanguy ML, De Reynies A, Mokhtari K, Figarella-Branger D, Delattre JY, Idbaih A; POLA Network.

Oncologist. 2018 Dec;23(12):1500-1510. doi: 10.1634/theoncologist.2017-0495. Epub 2018 Jul 17.


A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas.

Rosenberg S, Simeonova I, Bielle F, Verreault M, Bance B, Le Roux I, Daniau M, Nadaradjane A, Gleize V, Paris S, Marie Y, Giry M, Polivka M, Figarella-Branger D, Aubriot-Lorton MH, Villa C, Vasiljevic A, Lechapt-Zalcman E, Kalamarides M, Sharif A, Mokhtari K, Pagnotta SM, Iavarone A, Lasorella A, Huillard E, Sanson M.

Nat Commun. 2018 Jun 18;9(1):2371. doi: 10.1038/s41467-018-04622-w.


Diffuse gliomas classified by 1p/19q co-deletion, TERT promoter and IDH mutation status are associated with specific genetic risk loci.

Labreche K, Kinnersley B, Berzero G, Di Stefano AL, Rahimian A, Detrait I, Marie Y, Grenier-Boley B, Hoang-Xuan K, Delattre JY, Idbaih A, Houlston RS, Sanson M.

Acta Neuropathol. 2018 May;135(5):743-755. doi: 10.1007/s00401-018-1825-z. Epub 2018 Feb 19.


EGFR Amplification and IDH Mutations in Glioblastoma Patients of the Northeast of Morocco.

Senhaji N, Louati S, Chbani L, El Fatemi H, Hammas N, Mikou K, Maaroufi M, Benzagmout M, Boujraf S, El Bardai S, Giry M, Marie Y, Chaoui El Faiz M, Mokhtari K, Idbaih A, Amarti A, Bennis S.

Biomed Res Int. 2017;2017:8045859. doi: 10.1155/2017/8045859. Epub 2017 Jul 13.


Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing.

Euskirchen P, Bielle F, Labreche K, Kloosterman WP, Rosenberg S, Daniau M, Schmitt C, Masliah-Planchon J, Bourdeaut F, Dehais C, Marie Y, Delattre JY, Idbaih A.

Acta Neuropathol. 2017 Nov;134(5):691-703. doi: 10.1007/s00401-017-1743-5. Epub 2017 Jun 21.


Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.

Bielle F, Ducray F, Mokhtari K, Dehais C, Adle-Biassette H, Carpentier C, Chanut A, Polivka M, Poggioli S, Rosenberg S, Giry M, Marie Y, Duyckaerts C, Sanson M, Figarella-Branger D, Idbaih A; Pola Network.

Brain Pathol. 2017 Sep;27(5):567-579. doi: 10.1111/bpa.12434. Epub 2016 Oct 28.


Multi-omics analysis of primary glioblastoma cell lines shows recapitulation of pivotal molecular features of parental tumors.

Rosenberg S, Verreault M, Schmitt C, Guegan J, Guehennec J, Levasseur C, Marie Y, Bielle F, Mokhtari K, Hoang-Xuan K, Ligon K, Sanson M, Delattre JY, Idbaih A.

Neuro Oncol. 2017 Feb 1;19(2):219-228. doi: 10.1093/neuonc/now160.


Randomized clinical trial of the use of glyceryl trinitrate patches to aid arteriovenous fistula maturation.

Field M, McGrogan D, Marie Y, Joinson M, Andujar C, Dutton M, Krishnan H, Hodson J, van Dellen D, Inston NG.

Br J Surg. 2016 Sep;103(10):1269-75. doi: 10.1002/bjs.10217. Epub 2016 Jul 29.


Prevalence of IDH1/2 Mutations in Different Subtypes of Glioma in the North-East Population of Morocco.

Senhaji N, Louati S, Chbani L, Bardai SE, Mikou K, Maaroufi M, Benzagmout M, Faiz MC, Marie Y, Mokhtari K, Idbaih A, Amarti A, Bennis S.

Asian Pac J Cancer Prev. 2016;17(5):2649-53.


Genetic and neurodevelopmental spectrum of SYNGAP1-associated intellectual disability and epilepsy.

Mignot C, von Stülpnagel C, Nava C, Ville D, Sanlaville D, Lesca G, Rastetter A, Gachet B, Marie Y, Korenke GC, Borggraefe I, Hoffmann-Zacharska D, Szczepanik E, Rudzka-Dybała M, Yiş U, Çağlayan H, Isapof A, Marey I, Panagiotakaki E, Korff C, Rossier E, Riess A, Beck-Woedl S, Rauch A, Zweier C, Hoyer J, Reis A, Mironov M, Bobylova M, Mukhin K, Hernandez-Hernandez L, Maher B, Sisodiya S, Kuhn M, Glaeser D, Weckhuysen S, Myers CT, Mefford HC, Hörtnagel K, Biskup S; EuroEPINOMICS-RES MAE working group, Lemke JR, Héron D, Kluger G, Depienne C.

J Med Genet. 2016 Aug;53(8):511-22. doi: 10.1136/jmedgenet-2015-103451. Epub 2016 Mar 17. Erratum in: J Med Genet. 2016 Oct;53(10):720.


Mechanistic signatures of HPV insertions in cervical carcinomas.

Holmes A, Lameiras S, Jeannot E, Marie Y, Castera L, Sastre-Garau X, Nicolas A.

NPJ Genom Med. 2016 Mar 16;1:16004. doi: 10.1038/npjgenmed.2016.4. eCollection 2016.


Quantifying the heritability of glioma using genome-wide complex trait analysis.

Kinnersley B, Mitchell JS, Gousias K, Schramm J, Idbaih A, Labussière M, Marie Y, Rahimian A, Wichmann HE, Schreiber S, Hoang-Xuan K, Delattre JY, Nöthen MM, Mokhtari K, Lathrop M, Bondy M, Simon M, Sanson M, Houlston RS.

Sci Rep. 2015 Dec 2;5:17267. doi: 10.1038/srep17267.


Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas.

Verreault M, Schmitt C, Goldwirt L, Pelton K, Haidar S, Levasseur C, Guehennec J, Knoff D, Labussière M, Marie Y, Ligon AH, Mokhtari K, Hoang-Xuan K, Sanson M, Alexander BM, Wen PY, Delattre JY, Ligon KL, Idbaih A.

Clin Cancer Res. 2016 Mar 1;22(5):1185-96. doi: 10.1158/1078-0432.CCR-15-1015. Epub 2015 Oct 19. Erratum in: Clin Cancer Res. 2016 May 1;22(9):2313.


LRP1B deletion is associated with poor outcome for glioblastoma patients.

Tabouret E, Labussière M, Alentorn A, Schmitt Y, Marie Y, Sanson M.

J Neurol Sci. 2015 Nov 15;358(1-2):440-3. doi: 10.1016/j.jns.2015.09.345. Epub 2015 Sep 11.


Differential gene methylation in paired glioblastomas suggests a role of immune response pathways in tumor progression.

Alentorn A, Durán-Peña A, Malousi A, Marie Y, Mokhtari K, Sanson M, Hoang-Xuan K, Delattre JY, Idbaih A, Vecht C.

J Neurooncol. 2015 Sep;124(3):385-92. doi: 10.1007/s11060-015-1869-z. Epub 2015 Jul 30.


Patient survival following arteriovenous fistula formation.

McGrogan DG, Field MA, Maxwell AP, Marie Y, Inston NG.

J Vasc Access. 2015 May-Jun;16(3):195-9. doi: 10.5301/jva.5000343. Epub 2015 Jan 27.


Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma.

Di Stefano AL, Fucci A, Frattini V, Labussiere M, Mokhtari K, Zoppoli P, Marie Y, Bruno A, Boisselier B, Giry M, Savatovsky J, Touat M, Belaid H, Kamoun A, Idbaih A, Houillier C, Luo FR, Soria JC, Tabernero J, Eoli M, Paterra R, Yip S, Petrecca K, Chan JA, Finocchiaro G, Lasorella A, Sanson M, Iavarone A.

Clin Cancer Res. 2015 Jul 15;21(14):3307-17. doi: 10.1158/1078-0432.CCR-14-2199. Epub 2015 Jan 21.


VEGFA SNP rs2010963 is associated with vascular toxicity in recurrent glioblastomas and longer response to bevacizumab.

Di Stefano AL, Labussiere M, Lombardi G, Eoli M, Bianchessi D, Pasqualetti F, Farina P, Cuzzubbo S, Gallego-Perez-Larraya J, Boisselier B, Ducray F, Cheneau C, Moglia A, Finocchiaro G, Marie Y, Rahimian A, Hoang-Xuan K, Delattre JY, Mokhtari K, Sanson M.

J Neurooncol. 2015 Feb;121(3):499-504. doi: 10.1007/s11060-014-1677-x. Epub 2014 Dec 7.


TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations.

Labussière M, Di Stefano AL, Gleize V, Boisselier B, Giry M, Mangesius S, Bruno A, Paterra R, Marie Y, Rahimian A, Finocchiaro G, Houlston RS, Hoang-Xuan K, Idbaih A, Delattre JY, Mokhtari K, Sanson M.

Br J Cancer. 2014 Nov 11;111(10):2024-32. doi: 10.1038/bjc.2014.538. Epub 2014 Oct 14.


DGKI methylation status modulates the prognostic value of MGMT in glioblastoma patients treated with combined radio-chemotherapy with temozolomide.

Etcheverry A, Aubry M, Idbaih A, Vauleon E, Marie Y, Menei P, Boniface R, Figarella-Branger D, Karayan-Tapon L, Quillien V, Sanson M, de Tayrac M, Delattre JY, Mosser J.

PLoS One. 2014 Sep 18;9(9):e104455. doi: 10.1371/journal.pone.0104455. eCollection 2014.


Genetic analysis of matrin 3 gene in French amyotrophic lateral sclerosis patients and frontotemporal lobar degeneration with amyotrophic lateral sclerosis patients.

Millecamps S, De Septenville A, Teyssou E, Daniau M, Camuzat A, Albert M, LeGuern E, Galimberti D; French research network on FTD and FTD-ALS, Brice A, Marie Y, Le Ber I.

Neurobiol Aging. 2014 Dec;35(12):2882.e13-2882.e15. doi: 10.1016/j.neurobiolaging.2014.07.016. Epub 2014 Jul 18.


Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes.

Labussière M, Boisselier B, Mokhtari K, Di Stefano AL, Rahimian A, Rossetto M, Ciccarino P, Saulnier O, Paterra R, Marie Y, Finocchiaro G, Sanson M.

Neurology. 2014 Sep 23;83(13):1200-6. doi: 10.1212/WNL.0000000000000814. Epub 2014 Aug 22.


Diagnostic and prognostic value of preoperative combined GFAP, IGFBP-2, and YKL-40 plasma levels in patients with glioblastoma.

Gállego Pérez-Larraya J, Paris S, Idbaih A, Dehais C, Laigle-Donadey F, Navarro S, Capelle L, Mokhtari K, Marie Y, Sanson M, Hoang-Xuan K, Delattre JY, Mallet A.

Cancer. 2014 Dec 15;120(24):3972-80. doi: 10.1002/cncr.28949. Epub 2014 Aug 19.


Mutational analysis of primary central nervous system lymphoma.

Bruno A, Boisselier B, Labreche K, Marie Y, Polivka M, Jouvet A, Adam C, Figarella-Branger D, Miquel C, Eimer S, Houillier C, Soussain C, Mokhtari K, Daveau R, Hoang-Xuan K.

Oncotarget. 2014 Jul 15;5(13):5065-75.


IDH mutations: genotype-phenotype correlation and prognostic impact.

Wang XW, Ciccarino P, Rossetto M, Boisselier B, Marie Y, Desestret V, Gleize V, Mokhtari K, Sanson M, Labussière M.

Biomed Res Int. 2014;2014:540236. doi: 10.1155/2014/540236. Epub 2014 Apr 30.


Tumor and endothelial cell hybrids participate in glioblastoma vasculature.

El Hallani S, Colin C, El Houfi Y, Idbaih A, Boisselier B, Marie Y, Ravassard P, Labussière M, Mokhtari K, Thomas JL, Delattre JY, Eichmann A, Sanson M.

Biomed Res Int. 2014;2014:827327. doi: 10.1155/2014/827327. Epub 2014 Apr 24.


Patterns of blood flow as a predictor of maturation of arteriovenous fistula for haemodialysis.

Marie Y, Guy A, Tullett K, Krishnan H, Jones RG, Inston NG.

J Vasc Access. 2014 May-Jun;15(3):169-74. doi: 10.5301/jva.5000214. Epub 2014 Apr 7.


An ANOCEF genomic and transcriptomic microarray study of the response to irinotecan and bevacizumab in recurrent glioblastomas.

Laffaire J, Di Stefano AL, Chinot O, Idbaih A, Gallego Perez-Larraya J, Marie Y, Vintonenko N, Boisselier B, Farina P, Delattre JY, Figarella-Branger D, Honnorat J, Sanson M, Ducray F.

Biomed Res Int. 2014;2014:282815. doi: 10.1155/2014/282815. Epub 2014 Apr 2.


De novo mutations in HCN1 cause early infantile epileptic encephalopathy.

Nava C, Dalle C, Rastetter A, Striano P, de Kovel CG, Nabbout R, Cancès C, Ville D, Brilstra EH, Gobbi G, Raffo E, Bouteiller D, Marie Y, Trouillard O, Robbiano A, Keren B, Agher D, Roze E, Lesage S, Nicolas A, Brice A, Baulac M, Vogt C, El Hajj N, Schneider E, Suls A, Weckhuysen S, Gormley P, Lehesjoki AE, De Jonghe P, Helbig I, Baulac S, Zara F, Koeleman BP; EuroEPINOMICS RES Consortium, Haaf T, LeGuern E, Depienne C.

Nat Genet. 2014 Jun;46(6):640-5. doi: 10.1038/ng.2952. Epub 2014 Apr 20.


TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas.

Gillet E, Alentorn A, Doukouré B, Mundwiller E, van Thuijl HF, Reijneveld JC, Medina JA, Liou A, Marie Y, Mokhtari K, Hoang-Xuan K, Sanson M, Delattre JY, Idbaih A.

J Neurooncol. 2014 May;118(1):131-9. doi: 10.1007/s11060-014-1407-4. Epub 2014 Mar 4. Erratum in: J Neurooncol. 2014 Aug;119(1):225. Van Thuij, Hinke [corrected to van Thuijl, Hinke F].


Clinical value of chromosome arms 19q and 11p losses in low-grade gliomas.

Alentorn A, van Thuijl HF, Marie Y, Alshehhi H, Carpentier C, Boisselier B, Laigle-Donadey F, Mokhtari K, Scheinin I, Wesseling P, Ylstra B, Capelle L, Hoang-Xuan K, Sanson M, Delattre JY, Reijneveld JC, Idbaih A.

Neuro Oncol. 2014 Mar;16(3):400-8. doi: 10.1093/neuonc/not227. Epub 2013 Dec 12.


Ongoing and prolonged response in adult low-grade gliomas treated with radiotherapy.

Ducray F, Kaloshi G, Houillier C, Idbaih A, Ribba B, Psimaras D, Marie Y, Boisselier B, Alentorn A, Dainese L, Navarro S, Mokhtari K, Sanson M, Hoang-Xuan K, Delattre JY.

J Neurooncol. 2013 Nov;115(2):261-5. doi: 10.1007/s11060-013-1224-1. Epub 2013 Aug 17.


Transcranial high intensity focused ultrasound therapy guided by 7 TESLA MRI in a rat brain tumour model: a feasibility study.

Dervishi E, Larrat B, Pernot M, Adam C, Marie Y, Fink M, Delattre JY, Boch AL, Tanter M, Aubry JF.

Int J Hyperthermia. 2013 Sep;29(6):598-608. doi: 10.3109/02656736.2013.820357. Epub 2013 Aug 13.


Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity.

Viotti J, Duplan E, Caillava C, Condat J, Goiran T, Giordano C, Marie Y, Idbaih A, Delattre JY, Honnorat J, Checler F, Alves da Costa C.

Oncogene. 2014 Apr 3;33(14):1764-75. doi: 10.1038/onc.2013.124. Epub 2013 May 6.


Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222.

Enciso-Mora V, Hosking FJ, Di Stefano AL, Zelenika D, Shete S, Broderick P, Idbaih A, Delattre JY, Hoang-Xuan K, Marie Y, Labussière M, Alentorn A, Ciccarino P, Rossetto M, Armstrong G, Liu Y, Gousias K, Schramm J, Lau C, Hepworth SJ, Schoemaker M, Strauch K, Müller-Nurasyid M, Schreiber S, Franke A, Moebus S, Eisele L, Swerdlow A, Simon M, Bondy M, Lathrop M, Sanson M, Houlston RS.

Br J Cancer. 2013 May 28;108(10):2178-85. doi: 10.1038/bjc.2013.155. Epub 2013 Apr 9.


Deciphering the 8q24.21 association for glioma.

Enciso-Mora V, Hosking FJ, Kinnersley B, Wang Y, Shete S, Zelenika D, Broderick P, Idbaih A, Delattre JY, Hoang-Xuan K, Marie Y, Di Stefano AL, Labussière M, Dobbins S, Boisselier B, Ciccarino P, Rossetto M, Armstrong G, Liu Y, Gousias K, Schramm J, Lau C, Hepworth SJ, Strauch K, Müller-Nurasyid M, Schreiber S, Franke A, Moebus S, Eisele L, Forsti A, Hemminki K, Tomlinson IP, Swerdlow A, Lathrop M, Simon M, Bondy M, Sanson M, Houlston RS.

Hum Mol Genet. 2013 Jun 1;22(11):2293-302. doi: 10.1093/hmg/ddt063. Epub 2013 Feb 11.


Prognostic impact of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in malignant gliomas.

Wang XW, Boisselier B, Rossetto M, Marie Y, Idbaih A, Mokhtari K, Gousias K, Hoang-Xuan K, Delattre JY, Simon M, Labussière M, Sanson M.

Cancer. 2013 Feb 15;119(4):806-13. doi: 10.1002/cncr.27798. Epub 2012 Nov 26.


Association between glioma susceptibility loci and tumour pathology defines specific molecular etiologies.

Di Stefano AL, Enciso-Mora V, Marie Y, Desestret V, Labussière M, Boisselier B, Mokhtari K, Idbaih A, Hoang-Xuan K, Delattre JY, Houlston RS, Sanson M.

Neuro Oncol. 2013 May;15(5):542-7. doi: 10.1093/neuonc/nos284. Epub 2012 Nov 16.


Prevalence, clinico-pathological value, and co-occurrence of PDGFRA abnormalities in diffuse gliomas.

Alentorn A, Marie Y, Carpentier C, Boisselier B, Giry M, Labussière M, Mokhtari K, Hoang-Xuan K, Sanson M, Delattre JY, Idbaih A.

Neuro Oncol. 2012 Nov;14(11):1393-403. doi: 10.1093/neuonc/nos217. Epub 2012 Oct 16. Erratum in: Neuro Oncol. 2013 Mar;15(3):403.


Detection of IDH1 mutation in the plasma of patients with glioma.

Boisselier B, Gállego Pérez-Larraya J, Rossetto M, Labussière M, Ciccarino P, Marie Y, Delattre JY, Sanson M.

Neurology. 2012 Oct 16;79(16):1693-8. doi: 10.1212/WNL.0b013e31826e9b0a. Epub 2012 Oct 3.


Recurrent mutations of MYD88 and TBL1XR1 in primary central nervous system lymphomas.

Gonzalez-Aguilar A, Idbaih A, Boisselier B, Habbita N, Rossetto M, Laurenge A, Bruno A, Jouvet A, Polivka M, Adam C, Figarella-Branger D, Miquel C, Vital A, Ghesquières H, Gressin R, Delwail V, Taillandier L, Chinot O, Soubeyran P, Gyan E, Choquet S, Houillier C, Soussain C, Tanguy ML, Marie Y, Mokhtari K, Hoang-Xuan K.

Clin Cancer Res. 2012 Oct 1;18(19):5203-11. doi: 10.1158/1078-0432.CCR-12-0845. Epub 2012 Jul 26.


Insights revealed by high-throughput genomic arrays in nonglial primary brain tumors.

Alentorn A, Sanson M, Mokhtari K, Marie Y, Hoang-Xuan K, Delattre JY, Idbaih A.

Expert Rev Mol Diagn. 2012 Apr;12(3):265-77. doi: 10.1586/erm.12.17. Review.


The renal v-ATPase a4 subunit is expressed in specific subtypes of human gliomas.

Gleize V, Boisselier B, Marie Y, Poëa-Guyon S, Sanson M, Morel N.

Glia. 2012 May;60(6):1004-12. doi: 10.1002/glia.22332. Epub 2012 Mar 27.


RAD51 haploinsufficiency causes congenital mirror movements in humans.

Depienne C, Bouteiller D, Méneret A, Billot S, Groppa S, Klebe S, Charbonnier-Beaupel F, Corvol JC, Saraiva JP, Brueggemann N, Bhatia K, Cincotta M, Brochard V, Flamand-Roze C, Carpentier W, Meunier S, Marie Y, Gaussen M, Stevanin G, Wehrle R, Vidailhet M, Klein C, Dusart I, Brice A, Roze E.

Am J Hum Genet. 2012 Feb 10;90(2):301-7. doi: 10.1016/j.ajhg.2011.12.002. Epub 2012 Feb 2.


NFKBIA deletion in glioblastomas.

Idbaih A, Marie Y, Sanson M.

N Engl J Med. 2011 Jul 21;365(3):277; author reply 277-8. doi: 10.1056/NEJMc1103354. No abstract available.


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