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Items: 41

1.

Brugada phenocopy secondary to extensive inferior wall ischemia induced by coronary steal effect.

Guamán Valdivieso C, Ferrando-Castagnetto F, Marichal P, Acquistapace F, Trujillo P, Baranchuk A.

Ann Noninvasive Electrocardiol. 2019 Sep 9:e12689. doi: 10.1111/anec.12689. [Epub ahead of print]

PMID:
31498498
2.

[Ischemic T wave distortion associated with vasodilator-stress myocardial perfusion imaging].

Nogara R, Ferrando-Castagnetto F, Ricca-Mallada R, Ferrando R, Marichal P.

Medicina (B Aires). 2017;77(2):130-134. Spanish.

3.

Tachycardia-dependent bilateral bundle branch block in ischemic heart disease with systolic dysfunction: case report and review of prognostic implications.

Ferrando-Castagnetto F, Vidal A, Ricca-Mallada R, Nogara R, Marichal P, Martínez F.

Medwave. 2015 Oct 16;15(9):e6285. doi: 10.5867/medwave.2015.09.6285. Review. English, Spanish.

PMID:
26523696
4.

Synthesis and in vitro and in vivo antifungal activity of the hydroxy metabolites of saperconazole.

Meerpoel L, Heeres J, Backx LJ, Van der Veken LJ, Hendrickx R, Corens D, De Groot A, Leurs S, Van der Eycken L, Weerts J, Luyts P, Van Gerven F, Woestenborghs FA, Van Breda A, Oris M, van Dorsselaer P, Willemsens GH, Bellens D, Marichal PJ, Vanden Bossche HF, Odds FC.

ChemMedChem. 2010 May 3;5(5):757-69. doi: 10.1002/cmdc.201000040.

PMID:
20379992
5.

Advanced biological and chemical discovery (ABCD): centralizing discovery knowledge in an inherently decentralized world.

Agrafiotis DK, Alex S, Dai H, Derkinderen A, Farnum M, Gates P, Izrailev S, Jaeger EP, Konstant P, Leung A, Lobanov VS, Marichal P, Martin D, Rassokhin DN, Shemanarev M, Skalkin A, Stong J, Tabruyn T, Vermeiren M, Wan J, Xu XY, Yao X.

J Chem Inf Model. 2007 Nov-Dec;47(6):1999-2014. Epub 2007 Nov 1.

PMID:
17973472
6.

Data reduction and representation in drug discovery.

Howe TJ, Mahieu G, Marichal P, Tabruyn T, Vugts P.

Drug Discov Today. 2007 Jan;12(1-2):45-53. Epub 2006 Nov 13. Review.

PMID:
17198972
7.

Pyrrolo[1,2-a][1,4]benzodiazepine: a novel class of non-azole anti-dermatophyte anti-fungal agents.

Meerpoel L, Van Gestel J, Van Gerven F, Woestenborghs F, Marichal P, Sipido V, Terence G, Nash R, Corens D, Richards RD.

Bioorg Med Chem Lett. 2005 Jul 15;15(14):3453-8.

PMID:
15950472
8.

Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology.

Meerpoel L, Backx LJ, Van der Veken LJ, Heeres J, Corens D, De Groot A, Odds FC, Van Gerven F, Woestenborghs FA, Van Breda A, Oris M, van Dorsselaer P, Willemsens GH, Vermuyten KJ, Marichal PJ, Vanden Bossche HF, Ausma J, Borgers M.

J Med Chem. 2005 Mar 24;48(6):2184-93.

PMID:
15771461
9.

REALISIS: a medicinal chemistry-oriented reagent selection, library design, and profiling platform.

Yasri A, Berthelot D, Gijsen H, Thielemans T, Marichal P, Engels M, Hoflack J.

J Chem Inf Comput Sci. 2004 Nov-Dec;44(6):2199-206.

PMID:
15554690
10.

The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp., and Microsporum canis.

Vanden Bossche H, Ausma J, Bohets H, Vermuyten K, Willemsens G, Marichal P, Meerpoel L, Odds F, Borgers M.

Antimicrob Agents Chemother. 2004 Sep;48(9):3272-8.

11.
12.

Novel antifungals based on 4-substituted imidazole: a combinatorial chemistry approach to lead discovery and optimization.

Saha AK, Liu L, Simoneaux RL, Kukla MJ, Marichal P, Odds F.

Bioorg Med Chem Lett. 2000 Oct 2;10(19):2175-8.

PMID:
11012023
13.

Accumulation of 3-ketosteroids induced by itraconazole in azole-resistant clinical Candida albicans isolates.

Marichal P, Gorrens J, Laurijssens L, Vermuyten K, Van Hove C, Le Jeune L, Verhasselt P, Sanglard D, Borgers M, Ramaekers FC, Odds F, Vanden Bossche H.

Antimicrob Agents Chemother. 1999 Nov;43(11):2663-70.

14.

Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans.

Marichal P, Koymans L, Willemsens S, Bellens D, Verhasselt P, Luyten W, Borgers M, Ramaekers FCS, Odds FC, Vanden Bossche H.

Microbiology. 1999 Oct;145 ( Pt 10):2701-2713. doi: 10.1099/00221287-145-10-2701.

PMID:
10537192
15.

Rhodamine 6G efflux for the detection of CDR1-overexpressing azole-resistant Candida albicans strains.

Maesaki S, Marichal P, Vanden Bossche H, Sanglard D, Kohno S.

J Antimicrob Chemother. 1999 Jul;44(1):27-31.

PMID:
10459807
16.

Synergic effects of tactolimus and azole antifungal agents against azole-resistant Candida albican strains.

Maesaki S, Marichal P, Hossain MA, Sanglard D, Vanden Bossche H, Kohno S.

J Antimicrob Chemother. 1998 Dec;42(6):747-53.

PMID:
10052898
17.

Molecular biological characterization of an azole-resistant Candida glabrata isolate.

Marichal P, Vanden Bossche H, Odds FC, Nobels G, Warnock DW, Timmerman V, Van Broeckhoven C, Fay S, Mose-Larsen P.

Antimicrob Agents Chemother. 1997 Oct;41(10):2229-37.

18.

Hypothesis on the mechanism of resistance to fluconazole in Histoplasma capsulatum.

Wheat J, Marichal P, Vanden Bossche H, Le Monte A, Connolly P.

Antimicrob Agents Chemother. 1997 Feb;41(2):410-4.

19.

Use of a pedicled omental flap in the treatment of an infected vascular prosthetic graft.

Van Krunckelsven L, Marichal P, Hubens A.

Eur J Vasc Endovasc Surg. 1995 Aug;10(2):256-7. No abstract available.

20.

Origin of differences in susceptibility of Candida krusei to azole antifungal agents.

Marichal P, Gorrens J, Coene MC, Le Jeune L, Vanden Bossche H.

Mycoses. 1995 Mar-Apr;38(3-4):111-7.

PMID:
7477085
21.

Mechanisms of resistance to azole antifungals.

Marichal P, Vanden Bossche H.

Acta Biochim Pol. 1995;42(4):509-16. Review.

22.

Molecular mechanisms of drug resistance in fungi.

Vanden Bossche H, Marichal P, Odds FC.

Trends Microbiol. 1994 Oct;2(10):393-400. Review.

PMID:
7850208
23.

Mechanisms and clinical impact of antifungal drug resistance.

Vanden Bossche H, Warnock DW, Dupont B, Kerridge D, Sen Gupta S, Improvisi L, Marichal P, Odds FC, Provost F, Ronin O.

J Med Vet Mycol. 1994;32 Suppl 1:189-202. Review. No abstract available.

PMID:
7722785
24.

Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans.

Vanden Bossche H, Marichal P, Le Jeune L, Coene MC, Gorrens J, Cools W.

Antimicrob Agents Chemother. 1993 Oct;37(10):2101-5.

25.

Characterization of an azole-resistant Candida glabrata isolate.

vanden Bossche H, Marichal P, Odds FC, Le Jeune L, Coene MC.

Antimicrob Agents Chemother. 1992 Dec;36(12):2602-10.

26.

Mode of action of anti-Candida drugs: focus on terconazole and other ergosterol biosynthesis inhibitors.

Vanden Bossche H, Marichal P.

Am J Obstet Gynecol. 1991 Oct;165(4 Pt 2):1193-9.

PMID:
1951574
27.

Lipid-itraconazole interaction in lipid model membranes.

Brasseur R, Goormaghtigh E, Ruysschaert JM, Duquenoy PH, Marichal P, Vanden Bossche H.

J Pharm Pharmacol. 1991 Mar;43(3):167-71.

PMID:
1675272
28.

Biochemical basis for the activity and selectivity of oral antifungal drugs.

Vanden Bossche H, Marichal P, Gorrens J, Coene MC.

Br J Clin Pract Suppl. 1990 Sep;71:41-6. Review.

PMID:
2091733
29.

Saperconazole: a selective inhibitor of the cytochrome P-450-dependent ergosterol synthesis in Candida albicans, Aspergillus fumigatus and Trichophyton mentagrophytes.

Vanden Bossche H, Marichal P, Willemsens G, Bellens D, Gorrens J, Roels I, Coene MC, Le Jeune L, Janssen PA.

Mycoses. 1990 Jul-Aug;33(7-8):335-52.

PMID:
2090934
30.

Mutation in cytochrome P-450-dependent 14 alpha-demethylase results in decreased affinity for azole antifungals.

Vanden Bossche H, Marichal P, Gorrens J, Bellens D, Moereels H, Janssen PA.

Biochem Soc Trans. 1990 Feb;18(1):56-9. Review. No abstract available.

PMID:
2185088
31.

Biochemical approaches to selective antifungal activity. Focus on azole antifungals.

Vanden Bossche H, Marichal P, Gorrens J, Coene MC, Willemsens G, Bellens D, Roels I, Moereels H, Janssen PA.

Mycoses. 1989;32 Suppl 1:35-52. Review.

PMID:
2561184
32.

[Management, marketing, AIDS ... current issues in dentistry].

Bourguignon R, Marichal P.

Dent News. 1988 Feb;10(64):7, 9, 11 passim. French. No abstract available.

PMID:
3233796
33.

Mode of action studies. Basis for the search of new antifungal drugs.

Vanden Bossche H, Marichal P, Gorrens J, Geerts H, Janssen PA.

Ann N Y Acad Sci. 1988;544:191-207. No abstract available.

PMID:
2850749
34.

Anti-Candida drugs--the biochemical basis for their activity.

Vanden Bossche H, Willemsens G, Marichal P.

Crit Rev Microbiol. 1987;15(1):57-72. Review.

PMID:
3319421
35.

Effects of ketoconazole and itraconazole on growth and sterol synthesis in Pityrosporum ovale.

Marichal P, Gorrens J, Van Cutsem J, Van Gerven F, Vanden Bossche H.

J Med Vet Mycol. 1986 Dec;24(6):487-9.

PMID:
3033190
36.

Culture media for the study of the effects of azole derivatives on germ tube formation and hyphal growth of C. albicans.

Marichal P, Gorrens J, Van Cutsem J, Vanden Bossche H.

Mykosen. 1986 Feb;29(2):76-81. No abstract available.

PMID:
3515172
37.

A hemodynamic study of epidural versus intravenous anesthesia for aortofemoral bypass surgery.

Rosseel P, Marichal P, Lauwers LF, Baute L, Hanegreefs G.

Acta Anaesthesiol Belg. 1985 Dec;36(4):345-63.

PMID:
4096193
38.
39.

[Fever 13 years following an aortofemoral bypass operation].

Lins RL, Daelemans R, Marichal P, De Broe ME.

Acta Clin Belg. 1984;39(3):167-70. Dutch. No abstract available.

PMID:
6333130
40.

Hypothesis on the molecular basis of the antifungal activity of N-substituted imidazoles and triazoles.

Van den Bossche H, Willemsens G, Cools W, Marichal P, Lauwers W.

Biochem Soc Trans. 1983 Dec;11(6):665-7. No abstract available.

PMID:
6667774
41.

The interaction of miconazole and ketoconazole with lipids.

Van den Bossche H, Ruysschaert JM, Defrise-Quertain F, Willemsens G, Cornelissen F, Marichal P, Cools W, Van Cutsem J.

Biochem Pharmacol. 1982 Aug 15;31(16):2609-17.

PMID:
6291539

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