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Items: 1 to 50 of 89

1.

Mutation of Respiratory Syncytial Virus G Protein's CX3C Motif Attenuates Infection in Cotton Rats and Primary Human Airway Epithelial Cells.

Ha B, Chirkova T, Boukhvalova MS, Sun HY, Walsh EE, Anderson CS, Mariani TJ, Anderson LJ.

Vaccines (Basel). 2019 Jul 19;7(3). pii: E69. doi: 10.3390/vaccines7030069.

2.

Integration of transcriptomic and proteomic data identifies biological functions in cell populations from human infant lung.

Du Y, Clair GC, Al Alam D, Danopoulos S, Schnell D, Kitzmiller JA, Misra RS, Bhattacharya S, Warburton D, Mariani TJ, Pryhuber GS, Whitsett JA, Ansong C, Xu Y.

Am J Physiol Lung Cell Mol Physiol. 2019 Sep 1;317(3):L347-L360. doi: 10.1152/ajplung.00475.2018. Epub 2019 Jul 3.

PMID:
31268347
3.

Aims, Study Design, and Enrollment Results From the Assessing Predictors of Infant Respiratory Syncytial Virus Effects and Severity Study.

Walsh EE, Mariani TJ, Chu C, Grier A, Gill SR, Qiu X, Wang L, Holden-Wiltse J, Corbett A, Thakar J, Benoodt L, McCall MN, Topham DJ, Falsey AR, Caserta MT.

JMIR Res Protoc. 2019 Jun 6;8(6):e12907. doi: 10.2196/12907.

4.

A novel in vitro model of primary human pediatric lung epithelial cells.

Wang Q, Bhattacharya S, Mereness JA, Anderson C, Lillis JA, Misra RS, Romas S, Huyck H, Howell A, Bandyopadhyay G, Donlon K, Myers JR, Ashton J, Pryhuber GS, Mariani TJ.

Pediatr Res. 2019 Feb 18. doi: 10.1038/s41390-019-0340-9. [Epub ahead of print]

5.

Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia.

Ryan RM, Feng R, Bazacliu C, Ferkol TW, Ren CL, Mariani TJ, Poindexter BB, Wang F, Moore PE; Prematurity and Respiratory Outcome Program (PROP) Investigators.

J Pediatr. 2019 Apr;207:130-135.e2. doi: 10.1016/j.jpeds.2018.11.025. Epub 2019 Jan 4.

PMID:
30612812
6.

Type VI collagen promotes lung epithelial cell spreading and wound-closure.

Mereness JA, Bhattacharya S, Wang Q, Ren Y, Pryhuber GS, Mariani TJ.

PLoS One. 2018 Dec 14;13(12):e0209095. doi: 10.1371/journal.pone.0209095. eCollection 2018.

7.

Exome sequencing identifies gene variants and networks associated with extreme respiratory outcomes following preterm birth.

Hamvas A, Feng R, Bi Y, Wang F, Bhattacharya S, Mereness J, Kaushal M, Cotten CM, Ballard PL, Mariani TJ; PROP Investigators.

BMC Genet. 2018 Oct 20;19(1):94. doi: 10.1186/s12863-018-0679-7.

8.

Host Gene Expression in Nose and Blood for the Diagnosis of Viral Respiratory Infection.

Yu J, Peterson DR, Baran AM, Bhattacharya S, Wylie TN, Falsey AR, Mariani TJ, Storch GA.

J Infect Dis. 2019 Apr 1;219(7):1151-1161. doi: 10.1093/infdis/jiy608.

PMID:
30339221
9.

PPARα-mediated peroxisome induction compensates PPARγ-deficiency in bronchiolar club cells.

Karnati S, Oruqaj G, Janga H, Tumpara S, Colasante C, Van Veldhoven PP, Braverman N, Pilatz A, Mariani TJ, Baumgart-Vogt E.

PLoS One. 2018 Sep 13;13(9):e0203466. doi: 10.1371/journal.pone.0203466. eCollection 2018.

10.

Cell type-resolved human lung lipidome reveals cellular cooperation in lung function.

Kyle JE, Clair G, Bandyopadhyay G, Misra RS, Zink EM, Bloodsworth KJ, Shukla AK, Du Y, Lillis J, Myers JR, Ashton J, Bushnell T, Cochran M, Deutsch G, Baker ES, Carson JP, Mariani TJ, Xu Y, Whitsett JA, Pryhuber G, Ansong C.

Sci Rep. 2018 Sep 7;8(1):13455. doi: 10.1038/s41598-018-31640-x.

11.

Dissociation, cellular isolation, and initial molecular characterization of neonatal and pediatric human lung tissues.

Bandyopadhyay G, Huyck HL, Misra RS, Bhattacharya S, Wang Q, Mereness J, Lillis J, Myers JR, Ashton J, Bushnell T, Cochran M, Holden-Wiltse J, Katzman P, Deutsch G, Whitsett JA, Xu Y, Mariani TJ, Pryhuber GS.

Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L576-L583. doi: 10.1152/ajplung.00041.2018. Epub 2018 Jul 5.

PMID:
29975103
12.

Virus-Specific Antibody, Viral Load, and Disease Severity in Respiratory Syncytial Virus Infection.

Walsh EE, Wang L, Falsey AR, Qiu X, Corbett A, Holden-Wiltse J, Mariani TJ, Topham DJ, Caserta MT.

J Infect Dis. 2018 Jun 20;218(2):208-217. doi: 10.1093/infdis/jiy106.

13.

T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy.

Scheible KM, Emo J, Laniewski N, Baran AM, Peterson DR, Holden-Wiltse J, Bandyopadhyay S, Straw AG, Huyck H, Ashton JM, Tripi KS, Arul K, Werner E, Scalise T, Maffett D, Caserta M, Ryan RM, Reynolds AM, Ren CL, Topham DJ, Mariani TJ, Pryhuber GS.

JCI Insight. 2018 Feb 22;3(4). pii: 96724. doi: 10.1172/jci.insight.96724. eCollection 2018 Feb 22.

14.

Impact of prematurity and nutrition on the developing gut microbiome and preterm infant growth.

Grier A, Qiu X, Bandyopadhyay S, Holden-Wiltse J, Kessler HA, Gill AL, Hamilton B, Huyck H, Misra S, Mariani TJ, Ryan RM, Scholer L, Scheible KM, Lee YH, Caserta MT, Pryhuber GS, Gill SR.

Microbiome. 2017 Dec 11;5(1):158. doi: 10.1186/s40168-017-0377-0.

15.

Association of Dynamic Changes in the CD4 T-Cell Transcriptome With Disease Severity During Primary Respiratory Syncytial Virus Infection in Young Infants.

Mariani TJ, Qiu X, Chu C, Wang L, Thakar J, Holden-Wiltse J, Corbett A, Topham DJ, Falsey AR, Caserta MT, Walsh EE.

J Infect Dis. 2017 Nov 15;216(8):1027-1037. doi: 10.1093/infdis/jix400.

16.

LungMAP: The Molecular Atlas of Lung Development Program.

Ardini-Poleske ME, Clark RF, Ansong C, Carson JP, Corley RA, Deutsch GH, Hagood JS, Kaminski N, Mariani TJ, Potter SS, Pryhuber GS, Warburton D, Whitsett JA, Palmer SM, Ambalavanan N; LungMAP Consortium.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L733-L740. doi: 10.1152/ajplung.00139.2017. Epub 2017 Aug 10. Review.

17.

Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.

Bhattacharya S, Rosenberg AF, Peterson DR, Grzesik K, Baran AM, Ashton JM, Gill SR, Corbett AM, Holden-Wiltse J, Topham DJ, Walsh EE, Mariani TJ, Falsey AR.

Sci Rep. 2017 Jul 26;7(1):6548. doi: 10.1038/s41598-017-06738-3.

18.

MicroRNA expression profiling defines the impact of electronic cigarettes on human airway epithelial cells.

Solleti SK, Bhattacharya S, Ahmad A, Wang Q, Mereness J, Rangasamy T, Mariani TJ.

Sci Rep. 2017 Apr 24;7(1):1081. doi: 10.1038/s41598-017-01167-8.

19.

Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development.

Du Y, Kitzmiller JA, Sridharan A, Perl AK, Bridges JP, Misra RS, Pryhuber GS, Mariani TJ, Bhattacharya S, Guo M, Potter SS, Dexheimer P, Aronow B, Jobe AH, Whitsett JA, Xu Y.

Thorax. 2017 May;72(5):481-484. doi: 10.1136/thoraxjnl-2016-209598. Epub 2017 Jan 9.

20.

The Healthy Infant Nasal Transcriptome: A Benchmark Study.

Chu CY, Qiu X, Wang L, Bhattacharya S, Lofthus G, Corbett A, Holden-Wiltse J, Grier A, Tesini B, Gill SR, Falsey AR, Caserta MT, Walsh EE, Mariani TJ.

Sci Rep. 2016 Sep 23;6:33994. doi: 10.1038/srep33994.

21.

Flow-based sorting of neonatal lymphocyte populations for transcriptomics analysis.

Misra RS, Bhattacharya S, Huyck HL, Wang JC, Slaunwhite CG, Slaunwhite SL, Wightman TR, Secor-Socha S, Misra SK, Bushnell TP, Reynolds AM, Ryan RM, Quataert SA, Pryhuber GS, Mariani TJ.

J Immunol Methods. 2016 Oct;437:13-20. doi: 10.1016/j.jim.2016.07.001. Epub 2016 Jul 18.

22.

Serpine2 deficiency results in lung lymphocyte accumulation and bronchus-associated lymphoid tissue formation.

Solleti SK, Srisuma S, Bhattacharya S, Rangel-Moreno J, Bijli KM, Randall TD, Rahman A, Mariani TJ.

FASEB J. 2016 Jul;30(7):2615-26. doi: 10.1096/fj.201500159R. Epub 2016 Apr 8.

23.

Recurrent copy number variants associated with bronchopulmonary dysplasia.

Ahmad A, Bhattacharya S, Sridhar A, Iqbal AM, Mariani TJ.

Pediatr Res. 2016 Jun;79(6):940-5. doi: 10.1038/pr.2016.23. Epub 2016 Mar 14.

PMID:
26974307
24.

Respiratory disorders: Ironing out smoking-related airway disease.

Mariani TJ.

Nature. 2016 Mar 31;531(7596):586-7. doi: 10.1038/nature17309. Epub 2016 Mar 9. No abstract available.

PMID:
26958829
25.

The Oxygen Environment at Birth Specifies the Population of Alveolar Epithelial Stem Cells in the Adult Lung.

Yee M, Gelein R, Mariani TJ, Lawrence BP, O'Reilly MA.

Stem Cells. 2016 May;34(5):1396-406. doi: 10.1002/stem.2330. Epub 2016 Mar 7.

26.

Postnatal development of the bronchiolar club cells of distal airways in the mouse lung: stereological and molecular biological studies.

Karnati S, Graulich T, Oruqaj G, Pfreimer S, Seimetz M, Stamme C, Mariani TJ, Weissmann N, Mühlfeld C, Baumgart-Vogt E.

Cell Tissue Res. 2016 Jun;364(3):543-557. doi: 10.1007/s00441-015-2354-x. Epub 2016 Jan 21.

PMID:
26796206
27.

Update on Molecular Biology of Lung Development--Transcriptomics.

Mariani TJ.

Clin Perinatol. 2015 Dec;42(4):685-95. doi: 10.1016/j.clp.2015.08.001. Review.

28.

CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.

Legoux FP, Lim JB, Cauley AW, Dikiy S, Ertelt J, Mariani TJ, Sparwasser T, Way SS, Moon JJ.

Immunity. 2015 Nov 17;43(5):896-908. doi: 10.1016/j.immuni.2015.10.011. Epub 2015 Nov 10.

29.

Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants.

Scheible KM, Emo J, Yang H, Holden-Wiltse J, Straw A, Huyck H, Misra S, Topham DJ, Ryan RM, Reynolds AM, Mariani TJ, Pryhuber GS.

Clin Immunol. 2015 Dec;161(2):65-74. doi: 10.1016/j.clim.2015.07.003. Epub 2015 Jul 29.

30.

Airway epithelial cell PPARγ modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice.

Solleti SK, Simon DM, Srisuma S, Arikan MC, Bhattacharya S, Rangasamy T, Bijli KM, Rahman A, Crossno JT Jr, Shapiro SD, Mariani TJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 1;309(3):L293-304. doi: 10.1152/ajplung.00287.2014. Epub 2015 May 29.

31.

Prematurity and respiratory outcomes program (PROP): study protocol of a prospective multicenter study of respiratory outcomes of preterm infants in the United States.

Pryhuber GS, Maitre NL, Ballard RA, Cifelli D, Davis SD, Ellenberg JH, Greenberg JM, Kemp J, Mariani TJ, Panitch H, Ren C, Shaw P, Taussig LM, Hamvas A; Prematurity and Respiratory Outcomes Program Investigators.

BMC Pediatr. 2015 Apr 10;15:37. doi: 10.1186/s12887-015-0346-3.

32.

Integrated genomic analyses in bronchopulmonary dysplasia.

Ambalavanan N, Cotten CM, Page GP, Carlo WA, Murray JC, Bhattacharya S, Mariani TJ, Cuna AC, Faye-Petersen OM, Kelly D, Higgins RD; Genomics and Cytokine Subcommittees of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.

J Pediatr. 2015 Mar;166(3):531-7.e13. doi: 10.1016/j.jpeds.2014.09.052. Epub 2014 Nov 6.

33.

Alterations in gene expression and DNA methylation during murine and human lung alveolar septation.

Cuna A, Halloran B, Faye-Petersen O, Kelly D, Crossman DK, Cui X, Pandit K, Kaminski N, Bhattacharya S, Ahmad A, Mariani TJ, Ambalavanan N.

Am J Respir Cell Mol Biol. 2015 Jul;53(1):60-73. doi: 10.1165/rcmb.2014-0160OC.

34.

The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator.

Bhattacharya S, Zhou Z, Yee M, Chu CY, Lopez AM, Lunger VA, Solleti SK, Resseguie E, Buczynski B, Mariani TJ, O'Reilly MA.

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L516-23. doi: 10.1152/ajplung.00200.2014. Epub 2014 Aug 22.

35.

Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis.

Qiu W, Rogers AJ, Damask A, Raby BA, Klanderman BJ, Duan QL, Tyagi S, Niu S, Anderson C, Cahir-Mcfarland E, Mariani TJ, Carey V, Tantisira KG.

Hum Mol Genet. 2014 Sep 15;23(18):5017-24. doi: 10.1093/hmg/ddu191. Epub 2014 Apr 25.

36.

HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium.

Eckle T, Brodsky K, Bonney M, Packard T, Han J, Borchers CH, Mariani TJ, Kominsky DJ, Mittelbronn M, Eltzschig HK.

PLoS Biol. 2013 Sep;11(9):e1001665. doi: 10.1371/journal.pbio.1001665. Epub 2013 Sep 24.

37.

Chronic obstructive pulmonary disease genomics: yesterday, discovering population biomarkers; tomorrow, defining disease clusters.

Mariani TJ, Martinez F.

Am J Respir Crit Care Med. 2013 May 1;187(9):900-2. doi: 10.1164/rccm.201302-0340ED. No abstract available.

PMID:
23634854
38.

Molecular determinants of lung development.

Morrisey EE, Cardoso WV, Lane RH, Rabinovitch M, Abman SH, Ai X, Albertine KH, Bland RD, Chapman HA, Checkley W, Epstein JA, Kintner CR, Kumar M, Minoo P, Mariani TJ, McDonald DM, Mukouyama YS, Prince LS, Reese J, Rossant J, Shi W, Sun X, Werb Z, Whitsett JA, Gail D, Blaisdell CJ, Lin QS.

Ann Am Thorac Soc. 2013 Apr;10(2):S12-6. doi: 10.1513/AnnalsATS.201207-036OT. Review.

39.

Systems biology approaches to identify developmental bases for lung diseases.

Bhattacharya S, Mariani TJ.

Pediatr Res. 2013 Apr;73(4 Pt 2):514-22. doi: 10.1038/pr.2013.7. Epub 2013 Jan 11. Review.

40.

Stability of T cell phenotype and functional assays following heparinized umbilical cord blood collection.

Scheible K, Secor-Socha S, Wightman T, Wang H, Mariani TJ, Topham DJ, Pryhuber G, Quataert S.

Cytometry A. 2012 Nov;81(11):937-49. doi: 10.1002/cyto.a.22203. Epub 2012 Oct 1.

41.

Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia.

Bhattacharya S, Go D, Krenitsky DL, Huyck HL, Solleti SK, Lunger VA, Metlay L, Srisuma S, Wert SE, Mariani TJ, Pryhuber GS.

Am J Respir Crit Care Med. 2012 Aug 15;186(4):349-58. doi: 10.1164/rccm.201203-0406OC. Epub 2012 Jun 21.

42.

Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.

Brehm JM, Hagiwara K, Tesfaigzi Y, Bruse S, Mariani TJ, Bhattacharya S, Boutaoui N, Ziniti JP, Soto-Quiros ME, Avila L, Cho MH, Himes B, Litonjua AA, Jacobson F, Bakke P, Gulsvik A, Anderson WH, Lomas DA, Forno E, Datta S, Silverman EK, Celedón JC.

Thorax. 2011 Dec;66(12):1085-90. doi: 10.1136/thoraxjnl-2011-200017. Epub 2011 Sep 15.

43.

Peripheral blood gene expression profiles in COPD subjects.

Bhattacharya S, Tyagi S, Srisuma S, Demeo DL, Shapiro SD, Bueno R, Silverman EK, Reilly JJ, Mariani TJ.

J Clin Bioinforma. 2011 Apr 24;1(1):12. doi: 10.1186/2043-9113-1-12.

44.

Expression analysis of asthma candidate genes during human and murine lung development.

Melén E, Kho AT, Sharma S, Gaedigk R, Leeder JS, Mariani TJ, Carey VJ, Weiss ST, Tantisira KG.

Respir Res. 2011 Jun 23;12:86. doi: 10.1186/1465-9921-12-86.

45.

Conditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation.

Reddy NM, Potteti HR, Mariani TJ, Biswal S, Reddy SP.

Am J Respir Cell Mol Biol. 2011 Dec;45(6):1161-8. doi: 10.1165/rcmb.2011-0144OC. Epub 2011 Jun 9.

46.

Association of SERPINE2 with asthma.

Himes BE, Klanderman B, Ziniti J, Senter-Sylvia J, Soto-Quiros ME, Avila L, Celedón JC, Lange C, Mariani TJ, Lasky-Su J, Hersh CP, Raby BA, Silverman EK, Weiss ST, DeMeo DL.

Chest. 2011 Sep;140(3):667-674. doi: 10.1378/chest.10-2973. Epub 2011 Mar 24.

47.

SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development.

Hersh CP, Silverman EK, Gascon J, Bhattacharya S, Klanderman BJ, Litonjua AA, Lefebvre V, Sparrow D, Reilly JJ, Anderson WH, Lomas DA, Mariani TJ.

Am J Respir Crit Care Med. 2011 Jun 1;183(11):1482-9. doi: 10.1164/rccm.201010-1751OC. Epub 2011 Feb 17.

48.

PPARgamma deficiency results in reduced lung elastic recoil and abnormalities in airspace distribution.

Simon DM, Tsai LW, Ingenito EP, Starcher BC, Mariani TJ.

Respir Res. 2010 Jun 2;11:69. doi: 10.1186/1465-9921-11-69.

49.

Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis.

Srisuma S, Bhattacharya S, Simon DM, Solleti SK, Tyagi S, Starcher B, Mariani TJ.

Am J Respir Crit Care Med. 2010 Apr 15;181(8):838-50. doi: 10.1164/rccm.200904-0544OC. Epub 2010 Jan 21.

50.

Transcriptomic analysis of human lung development.

Kho AT, Bhattacharya S, Tantisira KG, Carey VJ, Gaedigk R, Leeder JS, Kohane IS, Weiss ST, Mariani TJ.

Am J Respir Crit Care Med. 2010 Jan 1;181(1):54-63. doi: 10.1164/rccm.200907-1063OC. Epub 2009 Oct 8.

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