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Items: 6


Evidence of epithelial to mesenchymal transition associated with increased tumorigenic potential in an immortalized normal prostate epithelial cell line.

Marian CO, Yang L, Zou YS, Gore C, Pong RC, Shay JW, Kabbani W, Hsieh JT, Raj GV.

Prostate. 2011 May;71(6):626-36. doi: 10.1002/pros.21278. Epub 2010 Oct 13.


The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth.

Marian CO, Cho SK, McEllin BM, Maher EA, Hatanpaa KJ, Madden CJ, Mickey BE, Wright WE, Shay JW, Bachoo RM.

Clin Cancer Res. 2010 Jan 1;16(1):154-63. doi: 10.1158/1078-0432.CCR-09-2850.


The effects of telomerase inhibition on prostate tumor-initiating cells.

Marian CO, Wright WE, Shay JW.

Int J Cancer. 2010 Jul 15;127(2):321-31. doi: 10.1002/ijc.25043.


Prostate tumor-initiating cells: a new target for telomerase inhibition therapy?

Marian CO, Shay JW.

Biochim Biophys Acta. 2009 Apr;1792(4):289-96. doi: 10.1016/j.bbadis.2009.02.012. Epub 2009 Mar 2. Review.


The maize Single myb histone 1 gene, Smh1, belongs to a novel gene family and encodes a protein that binds telomere DNA repeats in vitro.

Marian CO, Bordoli SJ, Goltz M, Santarella RA, Jackson LP, Danilevskaya O, Beckstette M, Meeley R, Bass HW.

Plant Physiol. 2003 Nov;133(3):1336-50. Epub 2003 Oct 23.

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