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Items: 1 to 50 of 188

1.

Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients With Heart Failure With Reduced Ejection Fraction: The DEFINE-HF Trial.

Nassif ME, Windsor S, Tang F, Khariton Y, Husain M, Inzucchi SE, McGuire D, Pitt B, Scirica BM, Austin B, Drazner M, Fong M, Givertz MM, Gordon R, Jermyn R, Katz S, Lamba S, Lanfear D, LaRue S, Lindenfeld J, Malone M, Margulies KB, Mentz R, Mutharasan RK, Pursley M, Umpierrez G, Kosiborod M; DEFINE-HF Investigators.

Circulation. 2019 Sep 16. doi: 10.1161/CIRCULATIONAHA.119.042929. [Epub ahead of print] No abstract available.

PMID:
31524498
2.

Targeting cardiac fibrosis with engineered T cells.

Aghajanian H, Kimura T, Rurik JG, Hancock AS, Leibowitz MS, Li L, Scholler J, Monslow J, Lo A, Han W, Wang T, Bedi K, Morley MP, Linares Saldana RA, Bolar NA, McDaid K, Assenmacher CA, Smith CL, Wirth D, June CH, Margulies KB, Jain R, Puré E, Albelda SM, Epstein JA.

Nature. 2019 Sep;573(7774):430-433. doi: 10.1038/s41586-019-1546-z. Epub 2019 Sep 11.

PMID:
31511695
3.

Cardiomyocyte d-dopachrome tautomerase protects against heart failure.

Ma Y, Su KN, Pfau D, Rao VS, Wu X, Hu X, Leng L, Du X, Piecychna M, Bedi K, Campbell SG, Eichmann A, Testani JM, Margulies KB, Bucala R, Young LH.

JCI Insight. 2019 Sep 5;4(17). pii: 128900. doi: 10.1172/jci.insight.128900.

4.

Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.

Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC Jr, Margulies KB, Sanz-Moreno V, Hobbs A, Hodivala-Dilke K.

J Pathol. 2019 Aug 19. doi: 10.1002/path.5340. [Epub ahead of print]

PMID:
31424556
5.

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.

Cordero P, Parikh VN, Chin ET, Erbilgin A, Gloudemans MJ, Shang C, Huang Y, Chang AC, Smith KS, Dewey F, Zaleta K, Morley M, Brandimarto J, Glazer N, Waggott D, Pavlovic A, Zhao M, Moravec CS, Tang WHW, Skreen J, Malloy C, Hannenhalli S, Li H, Ritter S, Li M, Bernstein D, Connolly A, Hakonarson H, Lusis AJ, Margulies KB, Depaoli-Roach AA, Montgomery SB, Wheeler MT, Cappola T, Ashley EA.

Nat Commun. 2019 Jun 24;10(1):2760. doi: 10.1038/s41467-019-10591-5.

6.

Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants.

Haggerty CM, Damrauer SM, Levin MG, Birtwell D, Carey DJ, Golden AM, Hartzel DN, Hu Y, Judy R, Kelly MA, Kember RL, Lester Kirchner H, Leader JB, Liang L, McDermott-Roe C, Babu A, Morley M, Nealy Z, Person TN, Pulenthiran A, Small A, Smelser DT, Stahl RC, Sturm AC, Williams H, Baras A, Margulies KB, Cappola TP, Dewey FE, Verma A, Zhang X, Correa A, Hall ME, Wilson JG, Ritchie MD, Rader DJ, Murray MF, Fornwalt BK, Arany Z.

Circulation. 2019 Jul 2;140(1):42-54. doi: 10.1161/CIRCULATIONAHA.119.039573. Epub 2019 Jun 20.

PMID:
31216868
7.

Tunable and Reversible Substrate Stiffness Reveals a Dynamic Mechanosensitivity of Cardiomyocytes.

Corbin EA, Vite A, Peyster EG, Bhoopalam M, Brandimarto J, Wang X, Bennett AI, Clark AT, Cheng X, Turner KT, Musunuru K, Margulies KB.

ACS Appl Mater Interfaces. 2019 Jun 12;11(23):20603-20614. doi: 10.1021/acsami.9b02446. Epub 2019 May 30.

PMID:
31074953
8.

Cardioprotective Effects of MTSS1 Enhancer Variants.

Morley MP, Wang X, Hu R, Brandimarto J, Tucker NR, Felix JF, Smith NL, van der Harst P, Ellinor PT, Margulies KB, Musunuru K, Cappola TP.

Circulation. 2019 Apr 23;139(17):2073-2076. doi: 10.1161/CIRCULATIONAHA.118.037939. No abstract available.

PMID:
31070942
9.

C-type natriuretic peptide co-ordinates cardiac structure and function.

Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS, Hobbs AJ.

Eur Heart J. 2019 Mar 21. pii: ehz093. doi: 10.1093/eurheartj/ehz093. [Epub ahead of print]

PMID:
30903134
10.

Targeting MRTF/SRF in CAP2-dependent dilated cardiomyopathy delays disease onset.

Xiong Y, Bedi K, Berritt S, Attipoe BK, Brooks TG, Wang K, Margulies KB, Field J.

JCI Insight. 2019 Mar 21;4(6). pii: 124629. doi: 10.1172/jci.insight.124629. eCollection 2019 Mar 21.

11.

Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial.

Borlaug BA, Anstrom KJ, Lewis GD, Shah SJ, Levine JA, Koepp GA, Givertz MM, Felker GM, LeWinter MM, Mann DL, Margulies KB, Smith AL, Tang WHW, Whellan DJ, Chen HH, Davila-Roman VG, McNulty S, Desvigne-Nickens P, Hernandez AF, Braunwald E, Redfield MM; National Heart, Lung, and Blood Institute Heart Failure Clinical Research Network.

JAMA. 2018 Nov 6;320(17):1764-1773. doi: 10.1001/jama.2018.14852.

12.

Microtubules Provide a Viscoelastic Resistance to Myocyte Motion.

Caporizzo MA, Chen CY, Salomon AK, Margulies KB, Prosser BL.

Biophys J. 2018 Nov 6;115(9):1796-1807. doi: 10.1016/j.bpj.2018.09.019. Epub 2018 Sep 28.

PMID:
30322798
13.

Targeting Calpain for Heart Failure Therapy: Implications From Multiple Murine Models.

Wang Y, Chen B, Huang CK, Guo A, Wu J, Zhang X, Chen R, Chen C, Kutschke W, Weiss RM, Boudreau RL, Margulies KB, Hong J, Song LS.

JACC Basic Transl Sci. 2018 Aug 28;3(4):503-517. doi: 10.1016/j.jacbts.2018.05.004. eCollection 2018 Aug.

14.

Liraglutide and weight loss among patients with advanced heart failure and a reduced ejection fraction: insights from the FIGHT trial.

Sharma A, Ambrosy AP, DeVore AD, Margulies KB, McNulty SE, Mentz RJ, Hernandez AF, Michael Felker G, Cooper LB, Lala A, Vader J, Groake JD, Borlaug BA, Velazquez EJ.

ESC Heart Fail. 2018 Dec;5(6):1035-1043. doi: 10.1002/ehf2.12334. Epub 2018 Aug 17.

15.

Increased Afterload Augments Sunitinib-Induced Cardiotoxicity in an Engineered Cardiac Microtissue Model.

Truitt R, Mu A, Corbin EA, Vite A, Brandimarto J, Ky B, Margulies KB.

JACC Basic Transl Sci. 2018 May 30;3(2):265-276. doi: 10.1016/j.jacbts.2017.12.007. eCollection 2018 Apr.

16.

Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure.

Chen CY, Caporizzo MA, Bedi K, Vite A, Bogush AI, Robison P, Heffler JG, Salomon AK, Kelly NA, Babu A, Morley MP, Margulies KB, Prosser BL.

Nat Med. 2018 Aug;24(8):1225-1233. doi: 10.1038/s41591-018-0046-2. Epub 2018 Jun 11.

17.

Multi-ethnic genome-wide association study for atrial fibrillation.

Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, März W, McManus DD, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, Müller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Paré G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribasés M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Seppälä I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH, Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Thériault S, Trompet S, Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, Völker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT.

Nat Genet. 2018 Jun 11;50(9):1225-1233. doi: 10.1038/s41588-018-0133-9.

18.

Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction.

Macri V, Brody JA, Arking DE, Hucker WJ, Yin X, Lin H, Mills RW, Sinner MF, Lubitz SA, Liu CT, Morrison AC, Alonso A, Li N, Fedorov VV, Janssen PM, Bis JC, Heckbert SR, Dolmatova EV, Lumley T, Sitlani CM, Cupples LA, Pulit SL, Newton-Cheh C, Barnard J, Smith JD, Van Wagoner DR, Chung MK, Vlahakes GJ, O'Donnell CJ, Rotter JI, Margulies KB, Morley MP, Cappola TP, Benjamin EJ, Muzny D, Gibbs RA, Jackson RD, Magnani JW, Herndon CN, Rich SS, Psaty BM, Milan DJ, Boerwinkle E, Mohler PJ, Sotoodehnia N, Ellinor PT.

Circ Genom Precis Med. 2018 May;11(5):e001663. doi: 10.1161/CIRCGEN.116.001663.

19.

A deep-learning classifier identifies patients with clinical heart failure using whole-slide images of H&E tissue.

Nirschl JJ, Janowczyk A, Peyster EG, Frank R, Margulies KB, Feldman MD, Madabhushi A.

PLoS One. 2018 Apr 3;13(4):e0192726. doi: 10.1371/journal.pone.0192726. eCollection 2018.

20.

Advanced Morphologic Analysis for Diagnosing Allograft Rejection: The Case of Cardiac Transplant Rejection.

Peyster EG, Madabhushi A, Margulies KB.

Transplantation. 2018 Aug;102(8):1230-1239. doi: 10.1097/TP.0000000000002189. Review.

21.

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects.

Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP.

Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901.

22.

Predicting Long Term Outcome in Patients Treated With Continuous Flow Left Ventricular Assist Device: The Penn-Columbia Risk Score.

Birati EY, Hanff TC, Maldonado D, Grandin EW, Kennel PJ, Mazurek JA, Vorovich E, Seigerman M, Howard JLL, Acker MA, Naka Y, Wald J, Goldberg LR, Jessup M, Atluri P, Margulies KB, Schulze PC, Rame JE.

J Am Heart Assoc. 2018 Mar 7;7(6). pii: e006408. doi: 10.1161/JAHA.117.006408.

23.

Determinants of Diuretic Responsiveness and Associated Outcomes During Acute Heart Failure Hospitalization: An Analysis From the NHLBI Heart Failure Network Clinical Trials.

Kiernan MS, Stevens SR, Tang WHW, Butler J, Anstrom KJ, Birati EY, Grodin JL, Gupta D, Margulies KB, LaRue S, Dávila-Román VG, Hernandez AF, de Las Fuentes L; NHLBI Heart Failure Clinical Trials Network Investigators.

J Card Fail. 2018 Jul;24(7):428-438. doi: 10.1016/j.cardfail.2018.02.002. Epub 2018 Mar 1.

24.

A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality.

Zhang X, Yoon JY, Morley M, McLendon JM, Mapuskar KA, Gutmann R, Mehdi H, Bloom HL, Dudley SC, Ellinor PT, Shalaby AA, Weiss R, Tang WHW, Moravec CS, Singh M, Taylor AL, Yancy CW, Feldman AM, McNamara DM, Irani K, Spitz DR, Breheny P, Margulies KB, London B, Boudreau RL.

J Clin Invest. 2018 Mar 1;128(3):1154-1163. doi: 10.1172/JCI95710. Epub 2018 Feb 19.

25.

GLP-1 Receptor Expression Within the Human Heart.

Baggio LL, Yusta B, Mulvihill EE, Cao X, Streutker CJ, Butany J, Cappola TP, Margulies KB, Drucker DJ.

Endocrinology. 2018 Apr 1;159(4):1570-1584. doi: 10.1210/en.2018-00004.

26.

Sparse simultaneous signal detection for identifying genetically controlled disease genes.

Zhao SD, Cai TT, Cappola TP, Margulies KB, Li H.

J Am Stat Assoc. 2017;112(519):1032-1046. doi: 10.1080/01621459.2016.1270825. Epub 2017 Jan 5.

27.

Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension.

Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.

Circulation. 2018 May 29;137(22):2360-2370. doi: 10.1161/CIRCULATIONAHA.117.033147. Epub 2018 Jan 19.

28.

Abundance, localization, and functional correlates of the advanced glycation end-product carboxymethyl lysine in human myocardium.

LeWinter MM, Taatjes D, Ashikaga T, Palmer B, Bishop N, VanBuren P, Bell S, Donaldson C, Meyer M, Margulies KB, Redfield M, Bull DA, Zile M.

Physiol Rep. 2017 Nov;5(20). pii: e13462. doi: 10.14814/phy2.13462.

29.

Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia.

Romanelli F, Corbo A, Salehi M, Yadav MC, Salman S, Petrosian D, Rashidbaigi OJ, Chait J, Kuruvilla J, Plummer M, Radichev I, Margulies KB, Gerdes AM, Pinkerton AB, Millán JL, Savinov AY, Savinova OV.

PLoS One. 2017 Oct 12;12(10):e0186426. doi: 10.1371/journal.pone.0186426. eCollection 2017.

30.

Prognostic Implications of Changes in Albumin Following Left Ventricular Assist Device Implantation in Patients With Severe Heart Failure.

Gopal DJ, Hanff TC, Mazurek JA, Grandin WE, Howard J, Forde-McLean R, Wald J, King K, Acker MA, Goldberg LR, Jessup M, Atluri P, Margulies KB, Rame EJ, Birati EY.

Am J Cardiol. 2017 Dec 1;120(11):2003-2007. doi: 10.1016/j.amjcard.2017.08.005. Epub 2017 Aug 30.

PMID:
28947307
31.

Cardiomyocyte-Specific Telomere Shortening is a Distinct Signature of Heart Failure in Humans.

Sharifi-Sanjani M, Oyster NM, Tichy ED, Bedi KC Jr, Harel O, Margulies KB, Mourkioti F.

J Am Heart Assoc. 2017 Sep 7;6(9). pii: e005086. doi: 10.1161/JAHA.116.005086.

32.

Mechanically dynamic PDMS substrates to investigate changing cell environments.

Yeh YC, Corbin EA, Caliari SR, Ouyang L, Vega SL, Truitt R, Han L, Margulies KB, Burdick JA.

Biomaterials. 2017 Nov;145:23-32. doi: 10.1016/j.biomaterials.2017.08.033. Epub 2017 Aug 17.

33.

In vivo label-free structural and biochemical imaging of coronary arteries using an integrated ultrasound and multispectral fluorescence lifetime catheter system.

Bec J, Phipps JE, Gorpas D, Ma D, Fatakdawala H, Margulies KB, Southard JA, Marcu L.

Sci Rep. 2017 Aug 21;7(1):8960. doi: 10.1038/s41598-017-08056-0.

34.

Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial.

Butler J, Anstrom KJ, Felker GM, Givertz MM, Kalogeropoulos AP, Konstam MA, Mann DL, Margulies KB, McNulty SE, Mentz RJ, Redfield MM, Tang WHW, Whellan DJ, Shah M, Desvigne-Nickens P, Hernandez AF, Braunwald E; National Heart Lung and Blood Institute Heart Failure Clinical Research Network.

JAMA Cardiol. 2017 Sep 1;2(9):950-958. doi: 10.1001/jamacardio.2017.2198.

35.

Myocardial apoptosis and mesenchymal stem cells with acute exercise.

Arisi MF, Chirico EN, Sebeny R, Muthukumaran G, Mu A, De Jonghe BC, Margulies KB, Libonati JR.

Physiol Rep. 2017 Jun;5(11). pii: e13297. doi: 10.14814/phy2.13297.

36.

Effects of organic and inorganic nitrate on aortic and carotid haemodynamics in heart failure with preserved ejection fraction.

Chirinos JA, Londono-Hoyos F, Zamani P, Beraun M, Haines P, Vasim I, Varakantam S, Phan TS, Cappola TP, Margulies KB, Townsend RR, Segers P.

Eur J Heart Fail. 2017 Nov;19(11):1507-1515. doi: 10.1002/ejhf.885. Epub 2017 May 25.

37.

Low ejection fraction in donor hearts is not directly associated with increased recipient mortality.

Chen CW, Sprys MH, Gaffey AC, Chung JJ, Margulies KB, Acker MA, Atluri P.

J Heart Lung Transplant. 2017 Jun;36(6):611-615. doi: 10.1016/j.healun.2017.02.001. Epub 2017 Feb 4.

PMID:
28314504
38.

Cytomegalovirus-Responsive CD8+ T Cells Expand After Solid Organ Transplantation in the Absence of CMV Disease.

Higdon LE, Trofe-Clark J, Liu S, Margulies KB, Sahoo MK, Blumberg E, Pinsky BA, Maltzman JS.

Am J Transplant. 2017 Aug;17(8):2045-2054. doi: 10.1111/ajt.14227. Epub 2017 Mar 13.

39.

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.

Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K.

Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13.

40.

Development of dilated cardiomyopathy and impaired calcium homeostasis with cardiac-specific deletion of ESRRβ.

Rowe GC, Asimaki A, Graham EL, Martin KD, Margulies KB, Das S, Saffitz J, Arany Z.

Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H662-H671. doi: 10.1152/ajpheart.00446.2016. Epub 2017 Jan 27.

41.

Detailed Echocardiographic Phenotyping in Breast Cancer Patients: Associations With Ejection Fraction Decline, Recovery, and Heart Failure Symptoms Over 3 Years of Follow-Up.

Narayan HK, Finkelman B, French B, Plappert T, Hyman D, Smith AM, Margulies KB, Ky B.

Circulation. 2017 Apr 11;135(15):1397-1412. doi: 10.1161/CIRCULATIONAHA.116.023463. Epub 2017 Jan 19.

42.

Lack of Benefit for Liraglutide in Heart Failure-Reply.

Margulies KB, McNulty SE, Cappola TP.

JAMA. 2016 Dec 13;316(22):2429-2430. doi: 10.1001/jama.2016.15394. No abstract available.

PMID:
27959992
43.

Pharmacokinetics and Pharmacodynamics of Inorganic Nitrate in Heart Failure With Preserved Ejection Fraction.

Zamani P, Tan V, Soto-Calderon H, Beraun M, Brandimarto JA, Trieu L, Varakantam S, Doulias PT, Townsend RR, Chittams J, Margulies KB, Cappola TP, Poole DC, Ischiropoulos H, Chirinos JA.

Circ Res. 2017 Mar 31;120(7):1151-1161. doi: 10.1161/CIRCRESAHA.116.309832. Epub 2016 Dec 7.

44.

Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.

Butler J, Epstein SE, Greene SJ, Quyyumi AA, Sikora S, Kim RJ, Anderson AS, Wilcox JE, Tankovich NI, Lipinski MJ, Ko YA, Margulies KB, Cole RT, Skopicki HA, Gheorghiade M.

Circ Res. 2017 Jan 20;120(2):332-340. doi: 10.1161/CIRCRESAHA.116.309717. Epub 2016 Nov 16.

PMID:
27856497
45.

Heart Failure, Left Ventricular Remodeling, and Circulating Nitric Oxide Metabolites.

Chirinos JA, Akers SR, Trieu L, Ischiropoulos H, Doulias PT, Tariq A, Vasim I, Koppula MR, Syed AA, Soto-Calderon H, Townsend RR, Cappola TP, Margulies KB, Zamani P.

J Am Heart Assoc. 2016 Oct 14;5(10). pii: e004133. Erratum in: J Am Heart Assoc. 2017 Feb 14;6(2):.

46.

Effect of Heart Failure With Preserved Ejection Fraction on Nitric Oxide Metabolites.

Zamani P, French B, Brandimarto JA, Doulias PT, Javaheri A, Chirinos JA, Margulies KB, Townsend RR, Sweitzer NK, Fang JC, Ischiropoulos H, Cappola TP.

Am J Cardiol. 2016 Dec 15;118(12):1855-1860. doi: 10.1016/j.amjcard.2016.08.077. Epub 2016 Sep 15.

47.

Effects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.

Margulies KB, Hernandez AF, Redfield MM, Givertz MM, Oliveira GH, Cole R, Mann DL, Whellan DJ, Kiernan MS, Felker GM, McNulty SE, Anstrom KJ, Shah MR, Braunwald E, Cappola TP; NHLBI Heart Failure Clinical Research Network.

JAMA. 2016 Aug 2;316(5):500-8. doi: 10.1001/jama.2016.10260.

48.

Right ventricular response to pulsatile load is associated with early right heart failure and mortality after left ventricular assist device.

Grandin EW, Zamani P, Mazurek JA, Troutman GS, Birati EY, Vorovich E, Chirinos JA, Tedford RJ, Margulies KB, Atluri P, Rame JE.

J Heart Lung Transplant. 2017 Jan;36(1):97-105. doi: 10.1016/j.healun.2016.06.015. Epub 2016 Jun 24.

PMID:
27469015
49.

Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal Injury.

Liu M, Verma N, Peng X, Srodulski S, Morris A, Chow M, Hersh LB, Chen J, Zhu H, Netea MG, Margulies KB, Despa S, Despa F.

Diabetes. 2016 Sep;65(9):2772-83. doi: 10.2337/db16-0044. Epub 2016 Jun 22.

50.

Transcription Factor 7-like 2 Mediates Canonical Wnt/β-Catenin Signaling and c-Myc Upregulation in Heart Failure.

Hou N, Ye B, Li X, Margulies KB, Xu H, Wang X, Li F.

Circ Heart Fail. 2016 Jun;9(6). doi: 10.1161/CIRCHEARTFAILURE.116.003010 e003010. Epub 2016 Jun 14.

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