Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 57

1.

"MPNST Epigenetics"-Letter.

Wassef M, Pasmant E, Margueron R.

Mol Cancer Res. 2019 Oct;17(10):2139. doi: 10.1158/1541-7786.MCR-19-0680. No abstract available.

PMID:
31575727
2.

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.

Ragazzini R, Pérez-Palacios R, Baymaz IH, Diop S, Ancelin K, Zielinski D, Michaud A, Givelet M, Borsos M, Aflaki S, Legoix P, Jansen PWTC, Servant N, Torres-Padilla ME, Bourc'his D, Fouchet P, Vermeulen M, Margueron R.

Nat Commun. 2019 Aug 26;10(1):3858. doi: 10.1038/s41467-019-11800-x.

3.

A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome.

Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, Droin N, Cagnard N, Kaltenbach S, Winter S, Kubasch AS, Bouscary D, Santini V, Toma A, Hunault M, Stamatoullas A, Gyan E, Cluzeau T, Platzbecker U, Adès L, Puy H, Stern MH, Karim Z, Mayeux P, Nemeth E, Park S, Ganz T, Kautz L, Kosmider O, Fontenay M.

Sci Transl Med. 2019 Jul 10;11(500). pii: eaav5467. doi: 10.1126/scitranslmed.aav5467.

PMID:
31292266
4.

The Polycomb protein Ezl1 mediates H3K9 and H3K27 methylation to repress transposable elements in Paramecium.

Frapporti A, Miró Pina C, Arnaiz O, Holoch D, Kawaguchi T, Humbert A, Eleftheriou E, Lombard B, Loew D, Sperling L, Guitot K, Margueron R, Duharcourt S.

Nat Commun. 2019 Jun 20;10(1):2710. doi: 10.1038/s41467-019-10648-5.

5.

EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.

Wassef M, Luscan A, Aflaki S, Zielinski D, Jansen PWTC, Baymaz HI, Battistella A, Kersouani C, Servant N, Wallace MR, Romero P, Kosmider O, Just PA, Hivelin M, Jacques S, Vincent-Salomon A, Vermeulen M, Vidaud M, Pasmant E, Margueron R.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6075-6080. doi: 10.1073/pnas.1814634116. Epub 2019 Mar 13.

6.

BAP1 complex promotes transcription by opposing PRC1-mediated H2A ubiquitylation.

Campagne A, Lee MK, Zielinski D, Michaud A, Le Corre S, Dingli F, Chen H, Shahidian LZ, Vassilev I, Servant N, Loew D, Pasmant E, Postel-Vinay S, Wassef M, Margueron R.

Nat Commun. 2019 Jan 21;10(1):348. doi: 10.1038/s41467-018-08255-x.

7.

Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells.

Wang Y, Long H, Yu J, Dong L, Wassef M, Zhuo B, Li X, Zhao J, Wang M, Liu C, Wen Z, Chang L, Chen P, Wang QF, Xu X, Margueron R, Li G.

BMC Biol. 2018 Sep 24;16(1):107. doi: 10.1186/s12915-018-0568-6.

8.

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, Deevy O, Glancy E, Fitzpatrick DJ, Mucha M, Watson A, Rice AM, Chammas P, Huang C, Pratt-Kelly I, Koseki Y, Nakayama M, Ishikura T, Streubel G, Wynne K, Hokamp K, McLysaght A, Ciferri C, Di Croce L, Cagney G, Margueron R, Koseki H, Bracken AP.

Mol Cell. 2018 May 3;70(3):408-421.e8. doi: 10.1016/j.molcel.2018.03.005. Epub 2018 Apr 5.

9.

A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation.

De Muyt A, Pyatnitskaya A, Andréani J, Ranjha L, Ramus C, Laureau R, Fernandez-Vega A, Holoch D, Girard E, Govin J, Margueron R, Couté Y, Cejka P, Guérois R, Borde V.

Genes Dev. 2018 Feb 1;32(3-4):283-296. doi: 10.1101/gad.308510.117. Epub 2018 Feb 9.

10.

Modulating BAP1 expression affects ROS homeostasis, cell motility and mitochondrial function.

Hebert L, Bellanger D, Guillas C, Campagne A, Dingli F, Loew D, Fievet A, Jacquemin V, Popova T, Jean D, Mechta-Grigoriou F, Margueron R, Stern MH.

Oncotarget. 2017 Aug 3;8(42):72513-72527. doi: 10.18632/oncotarget.19872. eCollection 2017 Sep 22.

11.

Histone propionylation is a mark of active chromatin.

Kebede AF, Nieborak A, Shahidian LZ, Le Gras S, Richter F, Gómez DA, Baltissen MP, Meszaros G, Magliarelli HF, Taudt A, Margueron R, Colomé-Tatché M, Ricci R, Daujat S, Vermeulen M, Mittler G, Schneider R.

Nat Struct Mol Biol. 2017 Dec;24(12):1048-1056. doi: 10.1038/nsmb.3490. Epub 2017 Oct 23.

PMID:
29058708
12.

Versatile and precise gene-targeting strategies for functional studies in mammalian cell lines.

Wassef M, Luscan A, Battistella A, Le Corre S, Li H, Wallace MR, Vidaud M, Margueron R.

Methods. 2017 May 15;121-122:45-54. doi: 10.1016/j.ymeth.2017.05.003. Epub 2017 May 10. Review.

PMID:
28499832
13.

Mechanisms Regulating PRC2 Recruitment and Enzymatic Activity.

Holoch D, Margueron R.

Trends Biochem Sci. 2017 Jul;42(7):531-542. doi: 10.1016/j.tibs.2017.04.003. Epub 2017 May 5. Review.

PMID:
28483375
14.

PRC2 is dispensable for HOTAIR-mediated transcriptional repression.

Portoso M, Ragazzini R, Brenčič Ž, Moiani A, Michaud A, Vassilev I, Wassef M, Servant N, Sargueil B, Margueron R.

EMBO J. 2017 Apr 13;36(8):981-994. doi: 10.15252/embj.201695335. Epub 2017 Feb 6.

15.

Chromatin biology: Breaking into the PRC2 cage.

Holoch D, Margueron R.

Nat Chem Biol. 2017 Apr;13(4):345-346. doi: 10.1038/nchembio.2313. Epub 2017 Jan 30. No abstract available.

PMID:
28135238
16.

The Multiple Facets of PRC2 Alterations in Cancers.

Wassef M, Margueron R.

J Mol Biol. 2017 Jun 30;429(13):1978-1993. doi: 10.1016/j.jmb.2016.10.012. Epub 2016 Oct 12. Review.

PMID:
27742591
17.

Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors.

Wassef M, Michaud A, Margueron R.

Cell Cycle. 2016 Sep;15(17):2256-62. doi: 10.1080/15384101.2016.1208872. Epub 2016 Jul 15.

18.

Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status.

Schoumacher M, Le Corre S, Houy A, Mulugeta E, Stern MH, Roman-Roman S, Margueron R.

Nat Med. 2016 Jun 7;22(6):577-8. doi: 10.1038/nm.4098. No abstract available.

PMID:
27270772
19.

Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis.

Wassef M, Rodilla V, Teissandier A, Zeitouni B, Gruel N, Sadacca B, Irondelle M, Charruel M, Ducos B, Michaud A, Caron M, Marangoni E, Chavrier P, Le Tourneau C, Kamal M, Pasmant E, Vidaud M, Servant N, Reyal F, Meseure D, Vincent-Salomon A, Fre S, Margueron R.

Genes Dev. 2015 Dec 15;29(24):2547-62. doi: 10.1101/gad.269522.115. Epub 2015 Dec 4.

20.

Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive.

Maupetit-Méhouas S, Montibus B, Nury D, Tayama C, Wassef M, Kota SK, Fogli A, Cerqueira Campos F, Hata K, Feil R, Margueron R, Nakabayashi K, Court F, Arnaud P.

Nucleic Acids Res. 2016 Jan 29;44(2):621-35. doi: 10.1093/nar/gkv960. Epub 2015 Sep 22.

21.

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.

Sanulli S, Justin N, Teissandier A, Ancelin K, Portoso M, Caron M, Michaud A, Lombard B, da Rocha ST, Offer J, Loew D, Servant N, Wassef M, Burlina F, Gamblin SJ, Heard E, Margueron R.

Mol Cell. 2015 Mar 5;57(5):769-783. doi: 10.1016/j.molcel.2014.12.020. Epub 2015 Jan 22.

22.

Transdifferentiation. Sequential histone-modifying activities determine the robustness of transdifferentiation.

Zuryn S, Ahier A, Portoso M, White ER, Morin MC, Margueron R, Jarriault S.

Science. 2014 Aug 15;345(6198):826-9. doi: 10.1126/science.1255885.

23.

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome.

da Rocha ST, Boeva V, Escamilla-Del-Arenal M, Ancelin K, Granier C, Matias NR, Sanulli S, Chow J, Schulz E, Picard C, Kaneko S, Helin K, Reinberg D, Stewart AF, Wutz A, Margueron R, Heard E.

Mol Cell. 2014 Jan 23;53(2):301-16. doi: 10.1016/j.molcel.2014.01.002.

24.

The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.

Mozzetta C, Pontis J, Fritsch L, Robin P, Portoso M, Proux C, Margueron R, Ait-Si-Ali S.

Mol Cell. 2014 Jan 23;53(2):277-89. doi: 10.1016/j.molcel.2013.12.005. Epub 2014 Jan 2.

25.

Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.

Son J, Shen SS, Margueron R, Reinberg D.

Genes Dev. 2013 Dec 15;27(24):2663-77. doi: 10.1101/gad.225888.113. Erratum in: Genes Dev. 2014 Apr 15;28(8):921.

26.

[Host epigenetic targeting by Legionella pneumophila].

Rolando M, Rusniok C, Margueron R, Buchrieser C.

Med Sci (Paris). 2013 Oct;29(10):843-5. doi: 10.1051/medsci/20132910010. Epub 2013 Oct 18. French. No abstract available.

27.

Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2.

Escamilla-Del-Arenal M, da Rocha ST, Spruijt CG, Masui O, Renaud O, Smits AH, Margueron R, Vermeulen M, Heard E.

Mol Cell Biol. 2013 Dec;33(24):5005-20. doi: 10.1128/MCB.00866-13. Epub 2013 Oct 21.

28.

Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication.

Rolando M, Sanulli S, Rusniok C, Gomez-Valero L, Bertholet C, Sahr T, Margueron R, Buchrieser C.

Cell Host Microbe. 2013 Apr 17;13(4):395-405. doi: 10.1016/j.chom.2013.03.004.

29.

Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer.

Tropberger P, Pott S, Keller C, Kamieniarz-Gdula K, Caron M, Richter F, Li G, Mittler G, Liu ET, Bühler M, Margueron R, Schneider R.

Cell. 2013 Feb 14;152(4):859-72. doi: 10.1016/j.cell.2013.01.032.

30.

Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.

Pinheiro I, Margueron R, Shukeir N, Eisold M, Fritzsch C, Richter FM, Mittler G, Genoud C, Goyama S, Kurokawa M, Son J, Reinberg D, Lachner M, Jenuwein T.

Cell. 2012 Aug 31;150(5):948-60. doi: 10.1016/j.cell.2012.06.048.

31.

EZH2 couples pancreatic regeneration to neoplastic progression.

Mallen-St Clair J, Soydaner-Azeloglu R, Lee KE, Taylor L, Livanos A, Pylayeva-Gupta Y, Miller G, Margueron R, Reinberg D, Bar-Sagi D.

Genes Dev. 2012 Mar 1;26(5):439-44. doi: 10.1101/gad.181800.111.

32.

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells.

Stojic L, Jasencakova Z, Prezioso C, Stützer A, Bodega B, Pasini D, Klingberg R, Mozzetta C, Margueron R, Puri PL, Schwarzer D, Helin K, Fischle W, Orlando V.

Epigenetics Chromatin. 2011 Sep 5;4:16. doi: 10.1186/1756-8935-4-16.

33.

Chromatin in the nuclear landscape.

Beck DB, Bonasio R, Kaneko S, Li G, Li G, Margueron R, Oda H, Sarma K, Sims RJ 3rd, Son J, Trojer P, Reinberg D.

Cold Spring Harb Symp Quant Biol. 2010;75:11-22. doi: 10.1101/sqb.2010.75.052. Epub 2011 Apr 18. Review.

34.

The Polycomb complex PRC2 and its mark in life.

Margueron R, Reinberg D.

Nature. 2011 Jan 20;469(7330):343-9. doi: 10.1038/nature09784. Review.

35.

Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA.

Kaneko S, Li G, Son J, Xu CF, Margueron R, Neubert TA, Reinberg D.

Genes Dev. 2010 Dec 1;24(23):2615-20. doi: 10.1101/gad.1983810.

36.

Highly compacted chromatin formed in vitro reflects the dynamics of transcription activation in vivo.

Li G, Margueron R, Hu G, Stokes D, Wang YH, Reinberg D.

Mol Cell. 2010 Apr 9;38(1):41-53. doi: 10.1016/j.molcel.2010.01.042.

37.

Chromatin structure and the inheritance of epigenetic information.

Margueron R, Reinberg D.

Nat Rev Genet. 2010 Apr;11(4):285-96. doi: 10.1038/nrg2752. Review.

38.

Jarid2 and PRC2, partners in regulating gene expression.

Li G, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D.

Genes Dev. 2010 Feb 15;24(4):368-80. doi: 10.1101/gad.1886410. Epub 2010 Feb 1.

39.

Role of the polycomb protein EED in the propagation of repressive histone marks.

Margueron R, Justin N, Ohno K, Sharpe ML, Son J, Drury WJ 3rd, Voigt P, Martin SR, Taylor WR, De Marco V, Pirrotta V, Reinberg D, Gamblin SJ.

Nature. 2009 Oct 8;461(7265):762-7. doi: 10.1038/nature08398. Epub 2009 Sep 20.

40.

Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.

Margueron R, Li G, Sarma K, Blais A, Zavadil J, Woodcock CL, Dynlacht BD, Reinberg D.

Mol Cell. 2008 Nov 21;32(4):503-18. doi: 10.1016/j.molcel.2008.11.004.

41.

Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo.

Sarma K, Margueron R, Ivanov A, Pirrotta V, Reinberg D.

Mol Cell Biol. 2008 Apr;28(8):2718-31. doi: 10.1128/MCB.02017-07. Epub 2008 Feb 19.

42.

Retinoblastoma tumor suppressor protein-dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit.

Blais A, van Oevelen CJ, Margueron R, Acosta-Alvear D, Dynlacht BD.

J Cell Biol. 2007 Dec 31;179(7):1399-412. doi: 10.1083/jcb.200705051.

43.

Suz12 binds to silenced regions of the genome in a cell-type-specific manner.

Squazzo SL, O'Geen H, Komashko VM, Krig SR, Jin VX, Jang SW, Margueron R, Reinberg D, Green R, Farnham PJ.

Genome Res. 2006 Jul;16(7):890-900. Epub 2006 Jun 2.

44.

ERalpha and ERbeta expression and transcriptional activity are differentially regulated by HDAC inhibitors.

Duong V, Licznar A, Margueron R, Boulle N, Busson M, Lacroix M, Katzenellenbogen BS, Cavaillès V, Lazennec G.

Oncogene. 2006 Mar 16;25(12):1799-806.

45.

Steps toward understanding the inheritance of repressive methyl-lysine marks in histones.

Reinberg D, Chuikov S, Farnham P, Karachentsev D, Kirmizis A, Kuzmichev A, Margueron R, Nishioka K, Preissner TS, Sarma K, Abate-Shen C, Steward R, Vaquero A.

Cold Spring Harb Symp Quant Biol. 2004;69:171-82. Review. No abstract available.

PMID:
16117647
46.

EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells.

Koyanagi M, Baguet A, Martens J, Margueron R, Jenuwein T, Bix M.

J Biol Chem. 2005 Sep 9;280(36):31470-7. Epub 2005 Jul 11.

47.

The key to development: interpreting the histone code?

Margueron R, Trojer P, Reinberg D.

Curr Opin Genet Dev. 2005 Apr;15(2):163-76. Review.

PMID:
15797199
48.

The nuclear receptor coactivator PGC-1alpha exhibits modes of interaction with the estrogen receptor distinct from those of SRC-1.

Bourdoncle A, Labesse G, Margueron R, Castet A, Cavaillès V, Royer CA.

J Mol Biol. 2005 Apr 15;347(5):921-34.

PMID:
15784253
49.

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation.

Kuzmichev A, Margueron R, Vaquero A, Preissner TS, Scher M, Kirmizis A, Ouyang X, Brockdorff N, Abate-Shen C, Farnham P, Reinberg D.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1859-64. Epub 2005 Jan 31.

50.

Transcriptional and posttranscriptional regulation of fibulin-1 by estrogens leads to differential induction of messenger ribonucleic acid variants in ovarian and breast cancer cells.

Bardin A, Moll F, Margueron R, Delfour C, Chu ML, Maudelonde T, Cavailles V, Pujol P.

Endocrinology. 2005 Feb;146(2):760-8. Epub 2004 Nov 4.

PMID:
15528301

Supplemental Content

Loading ...
Support Center