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Items: 24


Transcriptomics of Tasmanian Devil (Sarcophilus Harrisii) Ear Tissue Reveals Homogeneous Gene Expression Patterns across a Heterogeneous Landscape.

Fraik AK, Quackenbush C, Margres MJ, Comte S, Hamilton DG, Kozakiewicz CP, Jones M, Hamede R, Hohenlohe PA, Storfer A, Kelley JL.

Genes (Basel). 2019 Oct 12;10(10). pii: E801. doi: 10.3390/genes10100801.


Contemporary Demographic Reconstruction Methods Are Robust to Genome Assembly Quality: A Case Study in Tasmanian Devils.

Patton AH, Margres MJ, Stahlke AR, Hendricks S, Lewallen K, Hamede RK, Ruiz-Aravena M, Ryder O, McCallum HI, Jones ME, Hohenlohe PA, Storfer A.

Mol Biol Evol. 2019 Dec 1;36(12):2906-2921. doi: 10.1093/molbev/msz191.


Intraspecific sequence and gene expression variation contribute little to venom diversity in sidewinder rattlesnakes ( Crotalus cerastes).

Rautsaw RM, Hofmann EP, Margres MJ, Holding ML, Strickland JL, Mason AJ, Rokyta DR, Parkinson CL.

Proc Biol Sci. 2019 Jul 10;286(1906):20190810. doi: 10.1098/rspb.2019.0810. Epub 2019 Jul 3.


Tipping the Scales: The Migration-Selection Balance Leans toward Selection in Snake Venoms.

Margres MJ, Patton A, Wray KP, Hassinger ATB, Ward MJ, Lemmon EM, Lemmon AR, Rokyta DR.

Mol Biol Evol. 2019 Feb 1;36(2):271-282. doi: 10.1093/molbev/msy207.


The Genomic Basis of Tumor Regression in Tasmanian Devils (Sarcophilus harrisii).

Margres MJ, Ruiz-Aravena M, Hamede R, Jones ME, Lawrance MF, Hendricks SA, Patton A, Davis BW, Ostrander EA, McCallum H, Hohenlohe PA, Storfer A.

Genome Biol Evol. 2018 Nov 1;10(11):3012-3025. doi: 10.1093/gbe/evy229.


Large-effect loci affect survival in Tasmanian devils (Sarcophilus harrisii) infected with a transmissible cancer.

Margres MJ, Jones ME, Epstein B, Kerlin DH, Comte S, Fox S, Fraik AK, Hendricks SA, Huxtable S, Lachish S, Lazenby B, O'Rourke SM, Stahlke AR, Wiench CG, Hamede R, Schönfeld B, McCallum H, Miller MR, Hohenlohe PA, Storfer A.

Mol Ecol. 2018 Nov;27(21):4189-4199. doi: 10.1111/mec.14853. Epub 2018 Oct 5.


The devil is in the details: Genomics of transmissible cancers in Tasmanian devils.

Storfer A, Hohenlohe PA, Margres MJ, Patton A, Fraik AK, Lawrance M, Ricci LE, Stahlke AR, McCallum HI, Jones ME.

PLoS Pathog. 2018 Aug 2;14(8):e1007098. doi: 10.1371/journal.ppat.1007098. eCollection 2018 Aug. No abstract available.


Local prey community composition and genetic distance predict venom divergence among populations of the northern Pacific rattlesnake (Crotalus oreganus).

Holding ML, Margres MJ, Rokyta DR, Gibbs HL.

J Evol Biol. 2018 Oct;31(10):1513-1528. doi: 10.1111/jeb.13347. Epub 2018 Jul 22.


Evaluating the Performance of De Novo Assembly Methods for Venom-Gland Transcriptomics.

Holding ML, Margres MJ, Mason AJ, Parkinson CL, Rokyta DR.

Toxins (Basel). 2018 Jun 19;10(6). pii: E249. doi: 10.3390/toxins10060249.


Quantity, Not Quality: Rapid Adaptation in a Polygenic Trait Proceeded Exclusively through Expression Differentiation.

Margres MJ, Wray KP, Hassinger ATB, Ward MJ, McGivern JJ, Moriarty Lemmon E, Lemmon AR, Rokyta DR.

Mol Biol Evol. 2017 Dec 1;34(12):3099-3110. doi: 10.1093/molbev/msx231.


Selection To Increase Expression, Not Sequence Diversity, Precedes Gene Family Origin and Expansion in Rattlesnake Venom.

Margres MJ, Bigelow AT, Lemmon EM, Lemmon AR, Rokyta DR.

Genetics. 2017 Jul;206(3):1569-1580. doi: 10.1534/genetics.117.202655. Epub 2017 May 5.


The genetics of venom ontogeny in the eastern diamondback rattlesnake (Crotalus adamanteus).

Rokyta DR, Margres MJ, Ward MJ, Sanchez EE.

PeerJ. 2017 Apr 27;5:e3249. doi: 10.7717/peerj.3249. eCollection 2017.


Functional characterizations of venom phenotypes in the eastern diamondback rattlesnake (Crotalus adamanteus) and evidence for expression-driven divergence in toxic activities among populations.

Margres MJ, Walls R, Suntravat M, Lucena S, Sánchez EE, Rokyta DR.

Toxicon. 2016 Sep 1;119:28-38. doi: 10.1016/j.toxicon.2016.05.005. Epub 2016 May 11.


Expression Differentiation Is Constrained to Low-Expression Proteins over Ecological Timescales.

Margres MJ, Wray KP, Seavy M, McGivern JJ, Herrera ND, Rokyta DR.

Genetics. 2016 Jan;202(1):273-83. doi: 10.1534/genetics.115.180547. Epub 2015 Nov 6.


Post-transcriptional Mechanisms Contribute Little to Phenotypic Variation in Snake Venoms.

Rokyta DR, Margres MJ, Calvin K.

G3 (Bethesda). 2015 Sep 9;5(11):2375-82. doi: 10.1534/g3.115.020578.


Phenotypic integration in the feeding system of the eastern diamondback rattlesnake (Crotalus adamanteus).

Margres MJ, Wray KP, Seavy M, McGivern JJ, Sanader D, Rokyta DR.

Mol Ecol. 2015 Jul;24(13):3405-20. doi: 10.1111/mec.13240. Epub 2015 Jun 15.


The transcriptomic and proteomic basis for the evolution of a novel venom phenotype within the Timber Rattlesnake (Crotalus horridus).

Rokyta DR, Wray KP, McGivern JJ, Margres MJ.

Toxicon. 2015 May;98:34-48. doi: 10.1016/j.toxicon.2015.02.015. Epub 2015 Feb 26.


Early significant ontogenetic changes in snake venoms.

Wray KP, Margres MJ, Seavy M, Rokyta DR.

Toxicon. 2015 Mar;96:74-81. doi: 10.1016/j.toxicon.2015.01.010. Epub 2015 Jan 16.


RNA-seq and high-definition mass spectrometry reveal the complex and divergent venoms of two rear-fanged colubrid snakes.

McGivern JJ, Wray KP, Margres MJ, Couch ME, Mackessy SP, Rokyta DR.

BMC Genomics. 2014 Dec 3;15:1061. doi: 10.1186/1471-2164-15-1061.


Contrasting modes and tempos of venom expression evolution in two snake species.

Margres MJ, McGivern JJ, Seavy M, Wray KP, Facente J, Rokyta DR.

Genetics. 2015 Jan;199(1):165-76. doi: 10.1534/genetics.114.172437. Epub 2014 Nov 11.


Linking the transcriptome and proteome to characterize the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

Margres MJ, McGivern JJ, Wray KP, Seavy M, Calvin K, Rokyta DR.

J Proteomics. 2014 Jan 16;96:145-58. doi: 10.1016/j.jprot.2013.11.001. Epub 2013 Nov 12.


The venom-gland transcriptome of the eastern coral snake (Micrurus fulvius) reveals high venom complexity in the intragenomic evolution of venoms.

Margres MJ, Aronow K, Loyacano J, Rokyta DR.

BMC Genomics. 2013 Aug 2;14:531. doi: 10.1186/1471-2164-14-531.


The venom-gland transcriptome of the eastern diamondback rattlesnake (Crotalus adamanteus).

Rokyta DR, Lemmon AR, Margres MJ, Aronow K.

BMC Genomics. 2012 Jul 16;13:312. doi: 10.1186/1471-2164-13-312.

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