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Items: 1 to 50 of 235

1.

PCSK9 Inhibitor Use in the Real World: Data From the National Patient-Centered Research Network.

Chamberlain AM, Gong Y, Shaw KM, Bian J, Song WL, Linton MF, Fonseca V, Price-Haywood E, Guhl E, King JB, Shah RU, Puro J, Shenkman E, Pawloski PA, Margolis KL, Hernandez AF, Cooper-DeHoff RM.

J Am Heart Assoc. 2019 May 7;8(9):e011246. doi: 10.1161/JAHA.118.011246.

2.

Priorities Wizard: Multisite Web-Based Primary Care Clinical Decision Support Improved Chronic Care Outcomes with High Use Rates and High Clinician Satisfaction Rates.

Sperl-Hillen JM, Rossom RC, Kharbanda EO, Gold R, Geissal ED, Elliott TE, Desai JR, Rindal DB, Saman DM, Waring SC, Margolis KL, O'Connor PJ.

EGEMS (Wash DC). 2019 Apr 3;7(1):9. doi: 10.5334/egems.284. Review.

3.

Blood Pressure Assessment in Adults in Clinical Practice and Clinic-Based Research: JACC Scientific Expert Panel.

Muntner P, Einhorn PT, Cushman WC, Whelton PK, Bello NA, Drawz PE, Green BB, Jones DW, Juraschek SP, Margolis KL, Miller ER 3rd, Navar AM, Ostchega Y, Rakotz MK, Rosner B, Schwartz JE, Shimbo D, Stergiou GS, Townsend RR, Williamson JD, Wright JT Jr, Appel LJ; 2017 National Heart, Lung, and Blood Institute Working Group.

J Am Coll Cardiol. 2019 Jan 29;73(3):317-335. doi: 10.1016/j.jacc.2018.10.069. Review.

PMID:
30678763
4.

Baseline Characteristics of Participants in the ASPREE (Aspirin in Reducing Events in the Elderly) Study.

McNeil JJ, Woods RL, Nelson MR, Murray AM, Reid CM, Kirpach B, Storey E, Shah RC, Wolfe RS, Tonkin AM, Newman AB, Williamson JD, Lockery JE, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Trevaks RE, Orchard SG, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Grimm RH; ASPREE Investigator Group.

J Gerontol A Biol Sci Med Sci. 2019 Jan 22. doi: 10.1093/gerona/gly278. [Epub ahead of print] No abstract available.

5.

Long-term Outcomes of the Effects of Home Blood Pressure Telemonitoring and Pharmacist Management on Blood Pressure Among Adults With Uncontrolled Hypertension: Follow-up of a Cluster Randomized Clinical Trial.

Margolis KL, Asche SE, Dehmer SP, Bergdall AR, Green BB, Sperl-Hillen JM, Nyboer RA, Pawloski PA, Maciosek MV, Trower NK, O'Connor PJ.

JAMA Netw Open. 2018 Sep 7;1(5):e181617. doi: 10.1001/jamanetworkopen.2018.1617.

6.

Blood pressure checks and diagnosing hypertension (BP-CHECK): Design and methods of a randomized controlled diagnostic study comparing clinic, home, kiosk, and 24-hour ambulatory BP monitoring.

Green BB, Anderson ML, Campbell J, Cook AJ, Ehrlich K, Evers S, Hall YN, Hsu C, Joseph D, Klasnja P, Margolis KL, McClure JB, Munson SA, Thompson MJ.

Contemp Clin Trials. 2019 Apr;79:1-13. doi: 10.1016/j.cct.2019.01.003. Epub 2019 Jan 8.

PMID:
30634036
7.

Hypertension Treatment and Control and Risk of Falls in Older Women.

Margolis KL, Buchner DM, LaMonte MJ, Zhang Y, Di C, Rillamas-Sun E, Hunt J, Ikramuddin F, Li W, Marshall S, Rosenberg D, Stefanick ML, Wallace R, LaCroix AZ.

J Am Geriatr Soc. 2019 Apr;67(4):726-733. doi: 10.1111/jgs.15732. Epub 2019 Jan 7.

PMID:
30614525
8.

Accuracy of self-reported weight in the Women's Health Initiative.

Luo J, Thomson CA, Hendryx M, Tinker LF, Manson JE, Li Y, Nelson DA, Vitolins MZ, Seguin RA, Eaton CB, Wactawski-Wende J, Margolis KL.

Public Health Nutr. 2019 Apr;22(6):1019-1028. doi: 10.1017/S1368980018003002. Epub 2018 Nov 19.

PMID:
30449294
9.

Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women's Health Initiative.

Jacobson LT, Hade EM, Collins TC, Margolis KL, Waring ME, Van Horn LV, Silver B, Sattari M, Bird CE, Kimminau K, Wambach K, Stefanick ML.

J Am Heart Assoc. 2018 Sep 4;7(17):e008739. doi: 10.1161/JAHA.118.008739.

10.

Smoking cessation, weight gain, and risk of stroke among postmenopausal women.

Dinh PC, Schrader LA, Svensson CJ, Margolis KL, Silver B, Luo J.

Prev Med. 2019 Jan;118:184-190. doi: 10.1016/j.ypmed.2018.10.018. Epub 2018 Oct 22.

PMID:
30359645
11.

Economic Evaluation of the Home Blood Pressure Telemonitoring and Pharmacist Case Management to Control Hypertension (Hyperlink) Trial.

Dehmer SP, Maciosek MV, Trower NK, Asche SE, Bergdall AR, Nyboer RA, O'Connor PJ, Pawloski PA, Sperl-Hillen JM, Green BB, Margolis KL.

J Am Coll Clin Pharm. 2018 Oct;1(1):21-30. doi: 10.1002/jac5.1001. Epub 2018 Apr 14.

PMID:
30320302
12.

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.

McNeil JJ, Wolfe R, Woods RL, Tonkin AM, Donnan GA, Nelson MR, Reid CM, Lockery JE, Kirpach B, Storey E, Shah RC, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Johnston CI, Ryan J, Radziszewska B, Jelinek M, Malik M, Eaton CB, Brauer D, Cloud G, Wood EM, Mahady SE, Satterfield S, Grimm R, Murray AM; ASPREE Investigator Group.

N Engl J Med. 2018 Oct 18;379(16):1509-1518. doi: 10.1056/NEJMoa1805819. Epub 2018 Sep 16.

13.

Effect of Aspirin on Disability-free Survival in the Healthy Elderly.

McNeil JJ, Woods RL, Nelson MR, Reid CM, Kirpach B, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Ryan J, Radziszewska B, Grimm R, Murray AM; ASPREE Investigator Group.

N Engl J Med. 2018 Oct 18;379(16):1499-1508. doi: 10.1056/NEJMoa1800722. Epub 2018 Sep 16.

14.

Effect of Aspirin on All-Cause Mortality in the Healthy Elderly.

McNeil JJ, Nelson MR, Woods RL, Lockery JE, Wolfe R, Reid CM, Kirpach B, Shah RC, Ives DG, Storey E, Ryan J, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Radziszewska B, Grimm R, Murray AM; ASPREE Investigator Group.

N Engl J Med. 2018 Oct 18;379(16):1519-1528. doi: 10.1056/NEJMoa1803955. Epub 2018 Sep 16.

15.

Pooled Analysis of Nine Cohorts Reveals Breast Cancer Risk Factors by Tumor Molecular Subtype.

Gaudet MM, Gierach GL, Carter BD, Luo J, Milne RL, Weiderpass E, Giles GG, Tamimi RM, Eliassen AH, Rosner B, Wolk A, Adami HO, Margolis KL, Gapstur SM, Garcia-Closas M, Brinton LA.

Cancer Res. 2018 Oct 15;78(20):6011-6021. doi: 10.1158/0008-5472.CAN-18-0502. Epub 2018 Sep 5.

PMID:
30185547
16.

Key components of success in a randomized trial of blood pressure telemonitoring with medication therapy management pharmacists.

Beran M, Asche SE, Bergdall AR, Crabtree B, Green BB, Groen SE, Klotzle KJ, Michels RD, Nyboer RA, O'Connor PJ, Pawloski PA, Rehrauer DJ, Sperl-Hillen JM, Trower NK, Margolis KL.

J Am Pharm Assoc (2003). 2018 Nov - Dec;58(6):614-621. doi: 10.1016/j.japh.2018.07.001. Epub 2018 Aug 1.

PMID:
30077564
17.

Evaluation of the Pooled Cohort Risk Equations for Cardiovascular Risk Prediction in a Multiethnic Cohort From the Women's Health Initiative.

Mora S, Wenger NK, Cook NR, Liu J, Howard BV, Limacher MC, Liu S, Margolis KL, Martin LW, Paynter NP, Ridker PM, Robinson JG, Rossouw JE, Safford MM, Manson JE.

JAMA Intern Med. 2018 Sep 1;178(9):1231-1240. doi: 10.1001/jamainternmed.2018.2875.

PMID:
30039172
18.

Development of a standardized definition for clinically significant bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) trial.

Margolis KL, Mahady SE, Nelson MR, Ives DG, Satterfield S, Britt C, Ekram S, Lockery J, Schwartz EC, Woods RL, McNeil JJ, Wood EM.

Contemp Clin Trials Commun. 2018 May 22;11:30-36. doi: 10.1016/j.conctc.2018.05.015. eCollection 2018 Sep.

19.

Physical activity and weight gain after smoking cessation in postmenopausal women.

Luo J, Manson JE, Hendryx M, Shadyab AH, Johnson KC, Dinh PC Jr, Going SB, Chlebowski R, Stefanick ML, Margolis KL.

Menopause. 2019 Jan;26(1):16-23. doi: 10.1097/GME.0000000000001168.

PMID:
29994975
20.

Clinical decision support directed to primary care patients and providers reduces cardiovascular risk: a randomized trial.

Sperl-Hillen JM, Crain AL, Margolis KL, Ekstrom HL, Appana D, Amundson G, Sharma R, Desai JR, O'Connor PJ.

J Am Med Inform Assoc. 2018 Sep 1;25(9):1137-1146. doi: 10.1093/jamia/ocy085.

PMID:
29982627
21.

Impact of hormone therapy on Medicare spending in the Women's Health Initiative randomized clinical trials.

Shreibati JB, Manson JE, Margolis KL, Chlebowski RT, Stefanick ML, Hlatky MA.

Am Heart J. 2018 Apr;198:108-114. doi: 10.1016/j.ahj.2017.12.016. Epub 2017 Dec 27.

22.

Inventing a New Model of Hypertension Care for Black Men.

Margolis KL.

N Engl J Med. 2018 Apr 5;378(14):1345-1347. doi: 10.1056/NEJMe1803106. No abstract available.

PMID:
29617583
23.

Genetic variants in sex hormone pathways and the risk of type 2 diabetes among African American, Hispanic American, and European American postmenopausal women in the US.

Goto A, Chen BH, Chan KK, Lee C, Nelson SC, Crenshaw A, Bookman E, Margolis KL, Sale MM; MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium, Ng MCY, Reiner AP, Liu S.

J Diabetes. 2018 Jun;10(6):524-533. doi: 10.1111/1753-0407.12648. Epub 2018 Apr 6.

24.

Self-monitoring of blood pressure in hypertension: A systematic review and individual patient data meta-analysis.

Tucker KL, Sheppard JP, Stevens R, Bosworth HB, Bove A, Bray EP, Earle K, George J, Godwin M, Green BB, Hebert P, Hobbs FDR, Kantola I, Kerry SM, Leiva A, Magid DJ, Mant J, Margolis KL, McKinstry B, McLaughlin MA, Omboni S, Ogedegbe O, Parati G, Qamar N, Tabaei BP, Varis J, Verberk WJ, Wakefield BJ, McManus RJ.

PLoS Med. 2017 Sep 19;14(9):e1002389. doi: 10.1371/journal.pmed.1002389. eCollection 2017 Sep. Review.

25.

Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women's Health Initiative Randomized Trials.

Manson JE, Aragaki AK, Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Chlebowski RT, Howard BV, Thomson CA, Margolis KL, Lewis CE, Stefanick ML, Jackson RD, Johnson KC, Martin LW, Shumaker SA, Espeland MA, Wactawski-Wende J; WHI Investigators.

JAMA. 2017 Sep 12;318(10):927-938. doi: 10.1001/jama.2017.11217.

26.

Use of Calcium Channel Blockers and Breast Cancer Risk in the Women's Health Initiative.

Brasky TM, Krok-Schoen JL, Liu J, Chlebowski RT, Freudenheim JL, Lavasani S, Margolis KL, Qi L, Reding KW, Shields PG, Simon MS, Wactawski-Wende J, Wang A, Womack C, Manson JE.

Cancer Epidemiol Biomarkers Prev. 2017 Aug;26(8):1345-1348. doi: 10.1158/1055-9965.EPI-17-0096.

27.

The Impact of Antihypertensive Medications on Bone Mineral Density and Fracture Risk.

Barzilay JI, Davis BR, Pressel SL, Ghosh A, Puttnam R, Margolis KL, Whelton PK.

Curr Cardiol Rep. 2017 Sep;19(9):76. doi: 10.1007/s11886-017-0888-0. Review.

PMID:
28752275
28.

Benign breast disease and risk of thyroid cancer.

Luo J, Hendryx M, Nassir R, Cheng TD, Lane D, Margolis KL.

Cancer Causes Control. 2017 Sep;28(9):913-920. doi: 10.1007/s10552-017-0918-7. Epub 2017 Jul 6.

PMID:
28681104
29.

Red blood cell polyunsaturated fatty acids and mortality in the Women's Health Initiative Memory Study.

Harris WS, Luo J, Pottala JV, Espeland MA, Margolis KL, Manson JE, Wang L, Brasky TM, Robinson JG.

J Clin Lipidol. 2017 Jan - Feb;11(1):250-259.e5. doi: 10.1016/j.jacl.2016.12.013. Epub 2017 Jan 12.

30.

Effect of depression before breast cancer diagnosis on mortality among postmenopausal women.

Liang X, Margolis KL, Hendryx M, Reeves K, Wassertheil-Smoller S, Weitlauf J, Danhauer SC, Chlebowski RT, Caan B, Qi L, Lane D, Lavasani S, Luo J.

Cancer. 2017 Aug 15;123(16):3107-3115. doi: 10.1002/cncr.30688. Epub 2017 Apr 7.

31.

Strategies to Prioritize Clinical Options in Primary Care.

O'Connor PJ, Sperl-Hillen JM, Margolis KL, Kottke TE.

Ann Fam Med. 2017 Jan;15(1):10-13. doi: 10.1370/afm.2027. Epub 2017 Jan 6. No abstract available.

32.

Risk of Diabetes After Hysterectomy With or Without Oophorectomy in Postmenopausal Women.

Luo J, Manson JE, Urrutia RP, Hendryx M, LeBlanc ES, Margolis KL.

Am J Epidemiol. 2017 May 1;185(9):777-785. doi: 10.1093/aje/kwx023.

33.

Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study.

McNeil JJ, Woods RL, Nelson MR, Murray AM, Reid CM, Kirpach B, Storey E, Shah RC, Wolfe RS, Tonkin AM, Newman AB, Williamson JD, Lockery JE, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Trevaks RE, Orchard SG, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Grimm RH; ASPREE Investigator Group.

J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1586-1593. doi: 10.1093/gerona/glw342. Erratum in: J Gerontol A Biol Sci Med Sci. 2019 Jan 22;:.

34.

Predicting Hypertension Among Children With Incident Elevated Blood Pressure.

Daley MF, Reifler LM, Johnson ES, Sinaiko AR, Margolis KL, Parker ED, Greenspan LC, Lo JC, O'Connor PJ, Magid DJ.

Acad Pediatr. 2017 Apr;17(3):275-282. doi: 10.1016/j.acap.2016.09.009. Epub 2017 Feb 21.

35.

Intentional Weight Loss and Endometrial Cancer Risk.

Luo J, Chlebowski RT, Hendryx M, Rohan T, Wactawski-Wende J, Thomson CA, Felix AS, Chen C, Barrington W, Coday M, Stefanick M, LeBlanc E, Margolis KL.

J Clin Oncol. 2017 Apr 10;35(11):1189-1193. doi: 10.1200/JCO.2016.70.5822. Epub 2017 Feb 6.

36.

Metabolic Phenotype and Risk of Colorectal Cancer in Normal-Weight Postmenopausal Women.

Liang X, Margolis KL, Hendryx M, Rohan TE, Groessl EJ, Thomson CA, Kroenke CH, Simon MS, Lane D, Stefanick M, Luo J.

Cancer Epidemiol Biomarkers Prev. 2017 Feb;26(2):155-161. doi: 10.1158/1055-9965.EPI-16-0761.

37.

Venous thromboembolism incidence, recurrence, and mortality based on Women's Health Initiative data and Medicare claims.

Burwen DR, Wu C, Cirillo D, Rossouw JE, Margolis KL, Limacher M, Wallace R, Allison M, Eaton CB, Safford M, Freiberg M.

Thromb Res. 2017 Feb;150:78-85. doi: 10.1016/j.thromres.2016.11.015. Epub 2016 Nov 15.

PMID:
28063368
38.

Pooled analysis of active cigarette smoking and invasive breast cancer risk in 14 cohort studies.

Gaudet MM, Carter BD, Brinton LA, Falk RT, Gram IT, Luo J, Milne RL, Nyante SJ, Weiderpass E, Beane Freeman LE, Sandler DP, Robien K, Anderson KE, Giles GG, Chen WY, Feskanich D, Braaten T, Isaacs C, Butler LM, Koh WP, Wolk A, Adami HO, White E, Margolis KL, Thun MJ, Gapstur SM.

Int J Epidemiol. 2017 Jun 1;46(3):881-893. doi: 10.1093/ije/dyw288.

39.

Association of 3 Different Antihypertensive Medications With Hip and Pelvic Fracture Risk in Older Adults: Secondary Analysis of a Randomized Clinical Trial.

Puttnam R, Davis BR, Pressel SL, Whelton PK, Cushman WC, Louis GT, Margolis KL, Oparil S, Williamson J, Ghosh A, Einhorn PT, Barzilay JI; Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Collaborative Research Group.

JAMA Intern Med. 2017 Jan 1;177(1):67-76. doi: 10.1001/jamainternmed.2016.6821.

PMID:
27893045
40.

Calcium Supplements and Cardiovascular Disease Risk: What Do Clinicians and Patients Need to Know?

Margolis KL, Manson JE.

Ann Intern Med. 2016 Dec 20;165(12):884-885. doi: 10.7326/M16-2193. Epub 2016 Oct 25. No abstract available.

PMID:
27776361
41.

Trends in Incidence of Hospitalized Acute Myocardial Infarction in the Cardiovascular Research Network (CVRN).

Reynolds K, Go AS, Leong TK, Boudreau DM, Cassidy-Bushrow AE, Fortmann SP, Goldberg RJ, Gurwitz JH, Magid DJ, Margolis KL, McNeal CJ, Newton KM, Novotny R, Quesenberry CP Jr, Rosamond WD, Smith DH, VanWormer JJ, Vupputuri S, Waring SC, Williams MS, Sidney S.

Am J Med. 2017 Mar;130(3):317-327. doi: 10.1016/j.amjmed.2016.09.014. Epub 2016 Oct 14.

42.

Patient characteristics associated with greater blood pressure control in a randomized trial of home blood pressure telemonitoring and pharmacist management.

Asche SE, O'Connor PJ, Dehmer SP, Green BB, Bergdall AR, Maciosek MV, Nyboer RA, Pawloski PA, Sperl-Hillen JM, Trower NK, Margolis KL.

J Am Soc Hypertens. 2016 Nov;10(11):873-880. doi: 10.1016/j.jash.2016.09.004. Epub 2016 Sep 25.

43.

Relationships Between Caffeine Intake and Risk for Probable Dementia or Global Cognitive Impairment: The Women's Health Initiative Memory Study.

Driscoll I, Shumaker SA, Snively BM, Margolis KL, Manson JE, Vitolins MZ, Rossom RC, Espeland MA.

J Gerontol A Biol Sci Med Sci. 2016 Dec;71(12):1596-1602. Epub 2016 Sep 27.

44.

Research Needs to Improve Hypertension Treatment and Control in African Americans.

Whelton PK, Einhorn PT, Muntner P, Appel LJ, Cushman WC, Diez Roux AV, Ferdinand KC, Rahman M, Taylor HA, Ard J, Arnett DK, Carter BL, Davis BR, Freedman BI, Cooper LA, Cooper R, Desvigne-Nickens P, Gavini N, Go AS, Hyman DJ, Kimmel PL, Margolis KL, Miller ER 3rd, Mills KT, Mensah GA, Navar AM, Ogedegbe G, Rakotz MK, Thomas G, Tobin JN, Wright JT, Yoon SS, Cutler JA; National Heart, Lung, and Blood Institute Working Group on Research Needs to Improve Hypertension Treatment and Control in African Americans.

Hypertension. 2016 Nov;68(5):1066-1072. Epub 2016 Sep 12. Review. No abstract available.

45.

Orthostatic Hypotension in the ACCORD (Action to Control Cardiovascular Risk in Diabetes) Blood Pressure Trial: Prevalence, Incidence, and Prognostic Significance.

Fleg JL, Evans GW, Margolis KL, Barzilay J, Basile JN, Bigger JT, Cutler JA, Grimm R, Pedley C, Peterson K, Pop-Busui R, Sperl-Hillen J, Cushman WC.

Hypertension. 2016 Oct;68(4):888-95. doi: 10.1161/HYPERTENSIONAHA.116.07474. Epub 2016 Aug 8.

46.

Calcium plus vitamin D supplementation and height loss: findings from the Women's Health Initiative Calcium and Vitamin D clinical trial.

Crandall CJ, Aragaki AK, LeBoff MS, Li W, Wactawski-Wende J, Cauley JA, Margolis KL, Manson JE.

Menopause. 2016 Dec;23(12):1277-1286.

47.

Hysterectomy, Oophorectomy, and Risk of Thyroid Cancer.

Luo J, Hendryx M, Manson JE, Liang X, Margolis KL.

J Clin Endocrinol Metab. 2016 Oct;101(10):3812-3819. Epub 2016 Jul 26.

48.

Circle of Care: Extending Beyond Primary Caregivers to Examine Collaborative Caretaking in Adolescent Development.

Margolis KL, Fosco GM, Stormshak EA.

J Fam Issues. 2016 Jun;37(9):1179-1202. Epub 2014 May 29.

49.

A substudy evaluating treatment intensification on medication adherence among hypertensive patients receiving home blood pressure telemonitoring and pharmacist management.

Pawloski PA, Asche SE, Trower NK, Bergdall AR, Dehmer SP, Maciosek MV, Nyboer RA, O'Connor PJ, Sperl-Hillen JM, Green BB, Margolis KL.

J Clin Pharm Ther. 2016 Oct;41(5):493-8. doi: 10.1111/jcpt.12414. Epub 2016 Jun 30.

50.

Pre-existing diabetes and lung cancer prognosis.

Luo J, Hendryx M, Qi L, Ho GY, Margolis KL.

Br J Cancer. 2016 Jun 28;115(1):76-9. doi: 10.1038/bjc.2016.141. Epub 2016 May 19.

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