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Associations between QT interval subcomponents, HIV serostatus, and inflammation.

Wu KC, Bhondoekhan F, Haberlen SA, Ashikaga H, Brown TT, Budoff MJ, D'Souza G, Magnani JW, Kingsley LA, Palella FJ, Margolick JB, Martínez-Maza O, Altekruse SF, Soliman EZ, Post WS.

Ann Noninvasive Electrocardiol. 2019 Sep 19:e12705. doi: 10.1111/anec.12705. [Epub ahead of print]


Human Immunodeficiency Virus (HIV) Infection and Use of Illicit Substances Promote Secretion of Semen Exosomes that Enhance Monocyte Adhesion and Induce Actin Reorganization and Chemotactic Migration.

Lyu Y, Kaddour H, Kopcho S, Panzner TD, Shouman N, Kim EY, Martinson J, McKay H, Martinez-Maza O, Margolick JB, Stapleton JT, Okeoma CM.

Cells. 2019 Sep 3;8(9). pii: E1027. doi: 10.3390/cells8091027.


Current Challenges and Solutions in Research and Clinical Care of Older Persons Living with HIV: Findings Presented at the 9th International Workshop on HIV and Aging.

Sundermann EE, Erlandson KM, Pope CN, Rubtsova A, Montoya J, Moore AA, Marzolini C, O'Brien KK, Pahwa S, Payne BAI, Rubin LH, Walmsley S, Haughey NJ, Montano M, Karris MY, Margolick JB, Moore DJ.

AIDS Res Hum Retroviruses. 2019 Sep 10. doi: 10.1089/AID.2019.0100. [Epub ahead of print]


Risk Factors for Falls, Falls With Injury, and Falls With Fracture Among Older Men With or at Risk of HIV Infection.

Erlandson KM, Zhang L, Ng DK, Althoff KN, Palella FJ Jr, Kingsley LA, Jacobson LP, Margolick JB, Lake JE, Brown TT.

J Acquir Immune Defic Syndr. 2019 Aug 1;81(4):e117-e126. doi: 10.1097/QAI.0000000000002074.


T-cell immunity against cytomegalovirus in HIV infection and aging: relationships with inflammation, immune activation, and frailty.

Tavenier J, Margolick JB, Leng SX.

Med Microbiol Immunol. 2019 Aug;208(3-4):289-294. doi: 10.1007/s00430-019-00591-z. Epub 2019 Mar 21. Review.


Impaired insulin sensitivity is associated with worsening cognition in HIV-infected patients.

Khuder SS, Chen S, Letendre S, Marcotte T, Grant I, Franklin D, Rubin LH, Margolick JB, Jacobson LP, Sacktor N, D'Souza G, Stosor V, Lake JE, Rapocciolo G, McArthur JC, Dickens AM, Haughey NJ.

Neurology. 2019 Mar 19;92(12):e1344-e1353. doi: 10.1212/WNL.0000000000007125. Epub 2019 Feb 20.


A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.

Bruner KM, Wang Z, Simonetti FR, Bender AM, Kwon KJ, Sengupta S, Fray EJ, Beg SA, Antar AAR, Jenike KM, Bertagnolli LN, Capoferri AA, Kufera JT, Timmons A, Nobles C, Gregg J, Wada N, Ho YC, Zhang H, Margolick JB, Blankson JN, Deeks SG, Bushman FD, Siliciano JD, Laird GM, Siliciano RF.

Nature. 2019 Feb;566(7742):120-125. doi: 10.1038/s41586-019-0898-8. Epub 2019 Jan 30.


Viremia copy-years and mortality among combination antiretroviral therapy-initiating HIV-positive individuals: how much viral load history is enough?

Wang R, Haberlen SA, Palella FJ Jr, Mugavero MJ, Margolick JB, Macatangay BJC, Martínez-Maza O, Jacobson LP, Abraham AG.

AIDS. 2018 Nov 13;32(17):2547-2556. doi: 10.1097/QAD.0000000000001986.


Predictors of electrocardiographic QT interval prolongation in men with HIV.

Wu KC, Zhang L, Haberlen SA, Ashikaga H, Brown TT, Budoff MJ, D'Souza G, Kingsley LA, Palella FJ, Margolick JB, Martínez-Maza O, Soliman EZ, Post WS.

Heart. 2019 Apr;105(7):559-565. doi: 10.1136/heartjnl-2018-313667. Epub 2018 Oct 26.


Effect of Testosterone Use on Bone Mineral Density in HIV-Infected Men.

Grant PM, Li X, Jacobson LP, Palella FJ Jr, Kingsley LA, Margolick JB, Dobs AS, Lake JE, Althoff KN, Brown TT.

AIDS Res Hum Retroviruses. 2019 Jan;35(1):75-80. doi: 10.1089/AID.2018.0150. Epub 2018 Nov 1.


Vitamin D Metabolites in Aging HIV-Infected Men: Does Inflammation Play a Role?

Zhang L, Brown TT, Margolick JB, Witt MD, Palella FJ Jr, Kingsley LA, Hoofnagle AN, Tin A, Jacobson LP, Abraham AG.

AIDS Res Hum Retroviruses. 2018 Oct 30. doi: 10.1089/AID.2018.0101. [Epub ahead of print]


The role of CD32 during HIV-1 infection.

Bertagnolli LN, White JA, Simonetti FR, Beg SA, Lai J, Tomescu C, Murray AJ, Antar AAR, Zhang H, Margolick JB, Hoh R, Deeks SG, Tebas P, Montaner LJ, Siliciano RF, Laird GM, Siliciano JD.

Nature. 2018 Sep;561(7723):E17-E19. doi: 10.1038/s41586-018-0494-3. Epub 2018 Sep 19. No abstract available.


Sexual role and HIV-1 set point viral load among men who have sex with men.

Stansfield SE, Mittler JE, Gottlieb GS, Murphy JT, Hamilton DT, Detels R, Wolinsky SM, Jacobson LP, Margolick JB, Rinaldo CR, Herbeck JT, Goodreau SM.

Epidemics. 2019 Mar;26:68-76. doi: 10.1016/j.epidem.2018.08.006. Epub 2018 Aug 30.


Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection.

Shan Z, Clish CB, Hua S, Scott JM, Hanna DB, Burk RD, Haberlen SA, Shah SJ, Margolick JB, Sears CL, Post WS, Landay AL, Lazar JM, Hodis HN, Anastos K, Kaplan RC, Qi Q.

J Infect Dis. 2018 Sep 22;218(9):1474-1479. doi: 10.1093/infdis/jiy356.


Abdominal obesity, sarcopenia, and osteoporosis are associated with frailty in men living with and without HIV.

Hawkins KL, Zhang L, Ng DK, Althoff KN, Palella FJ Jr, Kingsley LA, Jacobson LP, Margolick JB, Lake JE, Brown TT, Erlandson KM.

AIDS. 2018 Jun 19;32(10):1257-1266. doi: 10.1097/QAD.0000000000001829.


Long-term kidney function, proteinuria, and associated risks among HIV-infected and uninfected men.

Palella FJ Jr, Li X, Gupta SK, Estrella MM, Phair JP, Margolick JB, Detels R, Kingsley L, Jacobson LP.

AIDS. 2018 Jun 19;32(10):1247-1256. doi: 10.1097/QAD.0000000000001807.


Relationship Between T-Cell Responses to CMV, Markers of Inflammation, and Frailty in HIV-uninfected and HIV-infected Men in the Multicenter AIDS Cohort Study.

Margolick JB, Bream JH, Nilles TL, Li H, Langan SJ, Deng S, Wang R, Wada N, Leng SX.

J Infect Dis. 2018 Jun 20;218(2):249-258. doi: 10.1093/infdis/jiy005.


The Role of Mitochondrial DNA Variation in Age-Related Decline in Gait Speed Among Older Men Living With Human Immunodeficiency Virus.

Sun J, Brown TT, Samuels DC, Hulgan T, D'Souza G, Jamieson BD, Erlandson KM, Martinson J, Palella FJ Jr, Margolick JB, Kirk GD, Schrack JA.

Clin Infect Dis. 2018 Aug 16;67(5):778-784. doi: 10.1093/cid/ciy151.


A prospective study of serum microbial translocation biomarkers and risk of AIDS-related non-Hodgkin lymphoma.

Epeldegui M, Magpantay L, Guo Y, Halec G, Cumberland WG, Yen PK, Macatangay B, Margolick JB, Rositch AF, Wolinsky S, Martinez-Maza O, Hussain SK.

AIDS. 2018 Apr 24;32(7):945-954. doi: 10.1097/QAD.0000000000001771.


Low thigh muscle mass is associated with coronary artery stenosis among HIV-infected and HIV-uninfected men: The Multicenter AIDS Cohort Study (MACS).

Tibuakuu M, Zhao D, Saxena A, Brown TT, Jacobson LP, Palella FJ Jr, Witt MD, Koletar SL, Margolick JB, Guallar E, Korada SKC, Budoff MJ, Post WS, Michos ED.

J Cardiovasc Comput Tomogr. 2018 Mar - Apr;12(2):131-138. doi: 10.1016/j.jcct.2018.01.007. Epub 2018 Jan 31.


Differential Relationships among Circulating Inflammatory and Immune Activation Biomediators and Impact of Aging and Human Immunodeficiency Virus Infection in a Cohort of Injection Drug Users.

Kirk GD, Dandorf S, Li H, Chen Y, Mehta SH, Piggott DA, Margolick JB, Leng SX.

Front Immunol. 2017 Oct 19;8:1343. doi: 10.3389/fimmu.2017.01343. eCollection 2017.


HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells.

Veenhuis RT, Freeman ZT, Korleski J, Cohen LK, Massaccesi G, Tomasi A, Boesch AW, Ackerman ME, Margolick JB, Blankson JN, Chattergoon MA, Cox AL.

J Clin Invest. 2017 Dec 1;127(12):4352-4364. doi: 10.1172/JCI95375. Epub 2017 Oct 30.


Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection.

Shan L, Deng K, Gao H, Xing S, Capoferri AA, Durand CM, Rabi SA, Laird GM, Kim M, Hosmane NN, Yang HC, Zhang H, Margolick JB, Li L, Cai W, Ke R, Flavell RA, Siliciano JD, Siliciano RF.

Immunity. 2017 Oct 17;47(4):766-775.e3. doi: 10.1016/j.immuni.2017.09.014.


Frailty and subclinical coronary atherosclerosis: The Multicenter AIDS Cohort Study (MACS).

Korada SKC, Zhao D, Tibuakuu M, Brown TT, Jacobson LP, Guallar E, Bolan RK, Palella FJ, Margolick JB, Martinson JJ, Budoff MJ, Post WS, Michos ED.

Atherosclerosis. 2017 Nov;266:240-247. doi: 10.1016/j.atherosclerosis.2017.08.026. Epub 2017 Aug 26.


Geriatric syndromes: new frontiers in HIV and sarcopenia.

Hawkins KL, Brown TT, Margolick JB, Erlandson KM.

AIDS. 2017 Jun 1;31 Suppl 2:S137-S146. doi: 10.1097/QAD.0000000000001444. Review.


Effect of prolonged freezing of semen on exosome recovery and biologic activity.

Welch JL, Madison MN, Margolick JB, Galvin S, Gupta P, Martínez-Maza O, Dash C, Okeoma CM.

Sci Rep. 2017 Mar 24;7:45034. doi: 10.1038/srep45034.


Frailty and Circulating Markers of Inflammation in HIV+ and HIV- Men in the Multicenter AIDS Cohort Study.

Margolick JB, Bream JH, Martínez-Maza O, Lopez J, Li X, Phair JP, Koletar SL, Jacobson LP.

J Acquir Immune Defic Syndr. 2017 Apr 1;74(4):407-417. doi: 10.1097/QAI.0000000000001261.


Multiplex assay reliability and long-term intra-individual variation of serologic inflammatory biomarkers.

McKay HS, Margolick JB, Martínez-Maza O, Lopez J, Phair J, Rappocciolo G, Denny TN, Magpantay LI, Jacobson LP, Bream JH.

Cytokine. 2017 Feb;90:185-192. doi: 10.1016/j.cyto.2016.09.018. Epub 2016 Dec 9.


Identification of the transcripts associated with spontaneous HCV clearance in individuals co-infected with HIV and HCV.

Chen Y, Shen C, Guha D, Ding M, Kulich S, Ashimkhanova A, Rinaldo C, Seaberg E, Margolick JB, Stosor V, Martínez-Maza O, Gupta P.

BMC Infect Dis. 2016 Nov 22;16(1):693.


Changes in weight and weight distribution across the lifespan among HIV-infected and -uninfected men and women.

Erlandson KM, Zhang L, Lake JE, Schrack J, Althoff K, Sharma A, Tien PC, Margolick JB, Jacobson LP, Brown TT.

Medicine (Baltimore). 2016 Nov;95(46):e5399.


The association of medication use with clearance or persistence of oral HPV infection.

Lam JO, Sugar EA, Cranston RD, Weber KM, Burk RD, Wiley DJ, Reddy S, Margolick JB, Strickler HD, Wentz A, Jacobson L, Coles CL, Bream JH, Rositch AF, Guo Y, Xiao W, Gillison ML, D'Souza G.

Cancer Causes Control. 2016 Dec;27(12):1491-1498. Epub 2016 Nov 1.


Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men With or at Risk for HIV Infection.

Erlandson KM, Ng DK, Jacobson LP, Margolick JB, Dobs AS, Palella FJ Jr, Lake JE, Bui H, Kingsley L, Brown TT.

J Infect Dis. 2017 Jan 15;215(2):228-237. doi: 10.1093/infdis/jiw523.


Effect of HIV-infection and cumulative viral load on age-related decline in grip strength.

Schrack JA, Jacobson LP, Althoff KN, Erlandson KM, Jamieson BD, Koletar SL, Phair J, Brown TT, Margolick JB; Multicenter AIDS Cohort Study.

AIDS. 2016 Nov 13;30(17):2645-2652.


Vitamin D Deficiency and Metabolism in HIV-Infected and HIV-Uninfected Men in the Multicenter AIDS Cohort Study.

Zhang L, Tin A, Brown TT, Margolick JB, Witt MD, Palella FJ Jr, Kingsley LA, Hoofnagle AN, Jacobson LP, Abraham AG.

AIDS Res Hum Retroviruses. 2017 Mar;33(3):261-270. doi: 10.1089/AID.2016.0144. Epub 2016 Nov 17.


Data on serologic inflammatory biomarkers assessed using multiplex assays and host characteristics in the Multicenter AIDS Cohort Study (MACS).

McKay HS, Bream JH, Margolick JB, Martínez-Maza O, Magpantay LI, Phair JP, Rinaldo CR, Abraham AG, Jacobson LP.

Data Brief. 2016 Aug 16;9:262-70. doi: 10.1016/j.dib.2016.08.019. eCollection 2016 Dec.


Speech audiometry findings from HIV+ and HIV- adults in the MACS and WIHS longitudinal cohort studies.

Torre P 3rd, Hoffman HJ, Springer G, Cox C, Young MA, Margolick JB, Plankey M.

J Commun Disord. 2016 Nov - Dec;64:103-109. doi: 10.1016/j.jcomdis.2016.07.004. Epub 2016 Jul 25.


Inflammatory Biomarkers and Mortality Risk Among HIV-Suppressed Men: A Multisite Prospective Cohort Study.

Wada NI, Bream JH, Martínez-Maza O, Macatangay B, Galvin SR, Margolick JB, Jacobson LP.

Clin Infect Dis. 2016 Oct 1;63(7):984-990. doi: 10.1093/cid/ciw409. Epub 2016 Jun 25.


Host factors associated with serologic inflammatory markers assessed using multiplex assays.

McKay HS, Bream JH, Margolick JB, Martínez-Maza O, Phair JP, Rinaldo CR, Abraham AG, Jacobson LP.

Cytokine. 2016 Sep;85:71-9. doi: 10.1016/j.cyto.2016.05.016. Epub 2016 Jun 10.


Association of serum cytokines with oral HPV clearance.

Lam JO, Bream JH, Sugar EA, Coles CL, Weber KM, Burk RD, Wiley DJ, Cranston RD, Reddy S, Margolick JB, Strickler HD, Wentz A, Jacobson L, Guo Y, Xiao W, Gillison ML, D'Souza G.

Cytokine. 2016 Jul;83:85-91. doi: 10.1016/j.cyto.2016.04.002. Epub 2016 Apr 8.


Development and Evaluation of a Modified Fourth-Generation Human Immunodeficiency Virus Enzyme Immunoassay for Cross-Sectional Incidence Estimation in Clade B Populations.

Kirkpatrick AR, Patel EU, Celum CL, Moore RD, Blankson JN, Mehta SH, Kirk GD, Margolick JB, Quinn TC, Eshleman SH, Laeyendecker O.

AIDS Res Hum Retroviruses. 2016 Aug;32(8):756-62. doi: 10.1089/AID.2015.0198. Epub 2016 May 5.


The effect of cellular isolation and cryopreservation on the expression of markers identifying subsets of regulatory T cells.

Zhang W, Nilles TL, Johnson JR, Margolick JB.

J Immunol Methods. 2016 Apr;431:31-7. doi: 10.1016/j.jim.2016.02.004. Epub 2016 Feb 19.


Brief Report: Intestinal Microbiota-Produced Trimethylamine-N-Oxide and Its Association With Coronary Stenosis and HIV Serostatus.

Miller PE, Haberlen SA, Brown TT, Margolick JB, DiDonato JA, Hazen SL, Witt MD, Kingsley LA, Palella FJ Jr, Budoff M, Jacobson LP, Post WS, Sears CL.

J Acquir Immune Defic Syndr. 2016 May 1;72(1):114-8. doi: 10.1097/QAI.0000000000000937.


Longitudinal Changes Over 10 Years in Free Testosterone Among HIV-Infected and HIV-Uninfected Men.

Slama L, Jacobson LP, Li X, Palella FJ Jr, Margolick JB, Kingsley LA, Wiley DJ, Pialoux G, Dobs AS, Brown TT; Multicenter AIDS Cohort Study.

J Acquir Immune Defic Syndr. 2016 Jan 1;71(1):57-64. doi: 10.1097/QAI.0000000000000821.


Long-term impact of HIV wasting on physical function.

Erlandson KM, Li X, Abraham AG, Margolick JB, Lake JE, Palella FJ Jr, Koletar SL, Brown TT.

AIDS. 2016 Jan 28;30(3):445-54. doi: 10.1097/QAD.0000000000000932. Erratum in: AIDS. 2016 Jul 31;30(12):2007.


A Randomized Trial of Time-Limited Antiretroviral Therapy in Acute/Early HIV Infection.

Margolick JB, Apuzzo L, Singer J, Wong H, Lee T, Gallant JE, El-Helou P, Loutfy MR, Rachlis A, Fraser C, Kasper K, Tremblay C, Tossonian H, Conway B.

PLoS One. 2015 Nov 24;10(11):e0143259. doi: 10.1371/journal.pone.0143259. eCollection 2015.


Regulatory T Cells, Frailty, and Immune Activation in Men Who Have Sex With Men in the Multicenter AIDS Cohort Study.

Zhang W, Nilles TL, Johnson JR, Margolick JB.

J Gerontol A Biol Sci Med Sci. 2015 Dec;70(12):1533-41. doi: 10.1093/gerona/glv132. Epub 2015 Aug 22.


Spontaneous Clearance of the Hepatitis C Virus Among Men Who Have Sex With Men.

Seaberg EC, Witt MD, Jacobson LP, Detels R, Rinaldo CR, Margolick JB, Young S, Phair JP, Thio CL.

Clin Infect Dis. 2015 Nov 1;61(9):1381-8. doi: 10.1093/cid/civ562. Epub 2015 Jul 14.


Accelerated Longitudinal Gait Speed Decline in HIV-Infected Older Men.

Schrack JA, Althoff KN, Jacobson LP, Erlandson KM, Jamieson BD, Koletar SL, Phair J, Ferrucci L, Brown TT, Margolick JB; Multicenter AIDS Cohort Study.

J Acquir Immune Defic Syndr. 2015 Dec 1;70(4):370-6. doi: 10.1097/QAI.0000000000000731.


Osteoprotegerin, but Not Receptor Activator for Nuclear Factor-κB Ligand, is Associated With Subclinical Coronary Atherosclerosis in HIV-Infected Men.

Ketlogetswe KS, McKibben R, Jacobson LP, Li X, Dobs AS, Budoff M, Witt MD, Palella FJ Jr, Kingsley L, Margolick JB, Post WS, Brown TT.

J Acquir Immune Defic Syndr. 2015 Dec 1;70(4):362-9. doi: 10.1097/QAI.0000000000000725.


High Oral Human Papillomavirus Type 16 Load Predicts Long-term Persistence in Individuals With or at Risk for HIV Infection.

Beachler DC, Guo Y, Xiao W, Burk RD, Minkoff H, Strickler HD, Cranston RD, Wiley DJ, Jacobson LP, Weber KM, Margolick JB, Sugar EA, Reddy S, Gillison ML, D'Souza G.

J Infect Dis. 2015 Nov 15;212(10):1588-91. doi: 10.1093/infdis/jiv273. Epub 2015 May 7.

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