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Items: 1 to 50 of 64

1.

Intrafamilial Variability of ADPKD.

Lanktree MB, Guiard E, Li W, Akbari P, Haghighi A, Iliuta IA, Shi B, Chen C, He N, Song X, Margetts PJ, Ingram AJ, Khalili K, Paterson AD, Pei Y.

Kidney Int Rep. 2019 May 7;4(7):995-1003. doi: 10.1016/j.ekir.2019.04.018. eCollection 2019 Jul.

2.

SMAD3-dependent and -independent pathways in glomerular injury associated with experimental glomerulonephritis.

Ghayur A, Padwal MK, Liu L, Zhang J, Margetts PJ.

Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F152-F162. doi: 10.1152/ajprenal.00406.2018. Epub 2019 May 29.

PMID:
31141397
3.

WNT signaling is required for peritoneal membrane angiogenesis.

Padwal M, Cheng G, Liu L, Boivin F, Gangji AS, Brimble KS, Bridgewater D, Margetts PJ.

Am J Physiol Renal Physiol. 2018 Jun 1;314(6):F1036-F1045. doi: 10.1152/ajprenal.00497.2017. Epub 2018 Jan 24.

4.

Characteristics and outcomes of Canadian MD/PhD program graduates: a cross-sectional survey.

Skinnider MA, Squair JW, Twa DDW, Ji JX, Kuzyk A, Wang X, Steadman PE, Zaslavsky K, Dey AK, Eisenberg MJ, Gagné ÈR, HayGlass KT, Lewis JF, Margetts PJ, Underhill DA, Rosenblum ND, Raymond LA.

CMAJ Open. 2017 Apr 25;5(2):E308-E314. doi: 10.9778/cmajo.20160152.

5.

Experimental systems to study the origin of the myofibroblast in peritoneal fibrosis.

Padwal M, Margetts PJ.

Kidney Res Clin Pract. 2016 Sep;35(3):133-41. doi: 10.1016/j.krcp.2016.07.003. Epub 2016 Jul 27. Review.

6.

Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study.

Rochwerg B, Cheung JH, Ribic CM, Lalji F, Clarke FJ, Gantareddy S, Ranganath N, Walele A, McDonald E, Meade MO, Cook DJ, Wilkieson TT, Clase CM, Margetts PJ, Gangji AS.

Can Respir J. 2016;2016:8671742. doi: 10.1155/2016/8671742. Epub 2016 Aug 15.

7.

Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling.

Padwal M, Siddique I, Wu L, Tang K, Boivin F, Liu L, Robertson J, Bridgewater D, West-Mays J, Gangji A, Brimble KS, Margetts PJ.

Nephrol Dial Transplant. 2017 Jan 1;32(1):50-61. doi: 10.1093/ndt/gfw076.

8.

Peritoneal Dialysis Catheter Increases Leukocyte Recruitment in the Mouse Parietal Peritoneum Microcirculation and Causes Fibrosis.

Kowalewska PM, Margetts PJ, Fox-Robichaud AE.

Perit Dial Int. 2016 Jan-Feb;36(1):7-15. doi: 10.3747/pdi.2014.00211. Epub 2015 Oct 16.

9.

Genetic Polymorphisms and Peritoneal Membrane Function.

Siddique I, Brimble KS, Walkin L, Summers A, Brenchley P, Herrick S, Margetts PJ.

Perit Dial Int. 2015 Sep-Oct;35(5):517-29. doi: 10.3747/pdi.2014.00049. Epub 2014 Nov 13. Review.

10.

Gremlin promotes peritoneal membrane injury in an experimental mouse model and is associated with increased solute transport in peritoneal dialysis patients.

Siddique I, Curran SP, Ghayur A, Liu L, Shi W, Hoff CM, Gangji AS, Brimble KS, Margetts PJ.

Am J Pathol. 2014 Nov;184(11):2976-84. doi: 10.1016/j.ajpath.2014.07.018. Epub 2014 Sep 3.

11.

The role of mouse strain differences in the susceptibility to fibrosis: a systematic review.

Walkin L, Herrick SE, Summers A, Brenchley PE, Hoff CM, Korstanje R, Margetts PJ.

Fibrogenesis Tissue Repair. 2013 Sep 25;6(1):18. doi: 10.1186/1755-1536-6-18.

12.

Peritoneal dialysis-moving from current status to the future.

Oh KH, Kim YL, Lo WK, Margetts PJ.

Int J Nephrol. 2013;2013:530713. doi: 10.1155/2013/530713. Epub 2013 Oct 24. No abstract available.

13.

Estimated GFR reporting influences recommendations for dialysis initiation.

Brimble KS, Mehrotra R, Tonelli M, Hawley CM, Castledine C, McDonald SP, Levidiotis V, Gangji AS, Treleaven DJ, Margetts PJ, Walsh M.

J Am Soc Nephrol. 2013 Nov;24(11):1737-42. doi: 10.1681/ASN.2013010035. Epub 2013 Aug 29.

14.

Transforming growth factor-beta and the glomerular filtration barrier.

Ghayur A, Margetts PJ.

Kidney Res Clin Pract. 2013 Mar 1;32(1):3-10.

15.

Twist: a new player in the epithelial-mesenchymal transition of the peritoneal mesothelial cells.

Margetts PJ.

Nephrol Dial Transplant. 2012 Nov;27(11):3978-81. doi: 10.1093/ndt/gfs172. Epub 2012 Jul 13.

PMID:
22798507
16.

Transforming growth factor β-induced peritoneal fibrosis is mouse strain dependent.

Margetts PJ, Hoff C, Liu L, Korstanje R, Walkin L, Summers A, Herrick S, Brenchley P.

Nephrol Dial Transplant. 2013 Aug;28(8):2015-27. doi: 10.1093/ndt/gfs289. Epub 2012 Jul 10.

PMID:
22785109
17.

Differentiation of bone marrow-derived cells into regenerated mesothelial cells in peritoneal remodeling using a peritoneal fibrosis mouse model.

Sekiguchi Y, Hamada C, Ro Y, Nakamoto H, Inaba M, Shimaoka T, Io H, Koyanagi I, Aruga S, Inuma J, Kaneko K, Hotta Y, Margetts PJ, Mochizuki H, Horikoshi S, Tomino Y.

J Artif Organs. 2012 Sep;15(3):272-82. doi: 10.1007/s10047-012-0648-2. Epub 2012 May 24.

PMID:
22622710
18.

TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium.

Carlisle RE, Heffernan A, Brimble E, Liu L, Jerome D, Collins CA, Mohammed-Ali Z, Margetts PJ, Austin RC, Dickhout JG.

Am J Physiol Renal Physiol. 2012 Aug 1;303(3):F467-81. doi: 10.1152/ajprenal.00481.2011. Epub 2012 May 16.

19.

Adenovirus-mediated gene transfer of TGF-β1 to the renal glomeruli leads to proteinuria.

Ghayur A, Liu L, Kolb M, Chawla A, Lambe S, Kapoor A, Margetts PJ.

Am J Pathol. 2012 Mar;180(3):940-51. doi: 10.1016/j.ajpath.2011.11.023. Epub 2011 Dec 25.

PMID:
22203053
20.

Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response.

Sekiguchi Y, Zhang J, Patterson S, Liu L, Hamada C, Tomino Y, Margetts PJ.

J Cell Mol Med. 2012 Aug;16(8):1934-45. doi: 10.1111/j.1582-4934.2011.01493.x.

21.

Management of hypophosphatemia in nocturnal hemodialysis with phosphate-containing enema: a technical study.

Su WS, Lekas P, Carlisle EJ, Cowin R, Bellamy J, Margetts PJ, Brimble KS, Clase CM, Gangji AS.

Hemodial Int. 2011 Apr;15(2):219-25. doi: 10.1111/j.1542-4758.2011.00533.x. Epub 2011 Mar 13.

PMID:
21395970
22.

Waist-to-Hip Ratio, Cardiovascular Outcomes, and Death in Peritoneal Dialysis Patients.

Su WS, Clase CM, Brimble KS, Margetts PJ, Wilkieson TJ, Gangji AS.

Int J Nephrol. 2010 Jul 5;2010:831243. doi: 10.4061/2010/831243.

23.

Renal tubular angiogenic dysregulation in anti-Thy1.1 glomerulonephritis.

Cina DP, Xu H, Liu L, Farkas L, Farkas D, Kolb M, Margetts PJ.

Am J Physiol Renal Physiol. 2011 Feb;300(2):F488-98. doi: 10.1152/ajprenal.00214.2010. Epub 2010 Nov 3.

24.

The pathophysiology of the peritoneal membrane.

Devuyst O, Margetts PJ, Topley N.

J Am Soc Nephrol. 2010 Jul;21(7):1077-85. doi: 10.1681/ASN.2009070694. Epub 2010 May 6. Review.

25.

Smad3-dependent and -independent pathways are involved in peritoneal membrane injury.

Patel P, Sekiguchi Y, Oh KH, Patterson SE, Kolb MR, Margetts PJ.

Kidney Int. 2010 Feb;77(4):319-28. doi: 10.1038/ki.2009.436. Epub 2009 Dec 2.

26.

Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells.

Patel P, West-Mays J, Kolb M, Rodrigues JC, Hoff CM, Margetts PJ.

Matrix Biol. 2010 Mar;29(2):97-106. doi: 10.1016/j.matbio.2009.10.004. Epub 2009 Nov 5.

PMID:
19896531
27.

Prolonged peritoneal gene expression using a helper-dependent adenovirus.

Liu L, Shi CX, Ghayur A, Zhang C, Su JY, Hoff CM, Margetts PJ.

Perit Dial Int. 2009 Sep-Oct;29(5):508-16.

PMID:
19776043
28.

Association between markers of inflammation, fibrosis and hypervolemia in peritoneal dialysis patients.

Gangji AS, Brimble KS, Margetts PJ.

Blood Purif. 2009;28(4):354-8. doi: 10.1159/000232937. Epub 2009 Sep 1.

PMID:
19729905
29.

Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis.

Moeller A, Gilpin SE, Ask K, Cox G, Cook D, Gauldie J, Margetts PJ, Farkas L, Dobranowski J, Boylan C, O'Byrne PM, Strieter RM, Kolb M.

Am J Respir Crit Care Med. 2009 Apr 1;179(7):588-94. doi: 10.1164/rccm.200810-1534OC. Epub 2009 Jan 16.

PMID:
19151190
30.

Temporal changes in MMP mRNA expression in the lens epithelium during anterior subcapsular cataract formation.

Nathu Z, Dwivedi DJ, Reddan JR, Sheardown H, Margetts PJ, West-Mays JA.

Exp Eye Res. 2009 Feb;88(2):323-30. doi: 10.1016/j.exer.2008.08.014. Epub 2008 Sep 6.

31.

Peritoneal morphological and functional changes associated with platelet-derived growth factor B.

Cina D, Patel P, Bethune JC, Thoma J, Rodriguez-Lecompte JC, Hoff CM, Liu L, Margetts PJ.

Nephrol Dial Transplant. 2009 Feb;24(2):448-57. doi: 10.1093/ndt/gfn498. Epub 2008 Sep 4.

PMID:
18775895
32.

Vascular endothelial growth factor expression in peritoneal mesothelial cells undergoing transdifferentiation.

Zhang J, Oh KH, Xu H, Margetts PJ.

Perit Dial Int. 2008 Sep-Oct;28(5):497-504.

PMID:
18708543
33.

Association between N-terminal propeptide B-type natriuretic peptide and markers of hypervolemia.

Gangji AS, Helal BA, Churchill DN, Brimble KS, Margetts PJ.

Perit Dial Int. 2008 May-Jun;28(3):308-11. No abstract available.

PMID:
18474925
34.

TGF-beta1 induces progressive pleural scarring and subpleural fibrosis.

Decologne N, Kolb M, Margetts PJ, Menetrier F, Artur Y, Garrido C, Gauldie J, Camus P, Bonniaud P.

J Immunol. 2007 Nov 1;179(9):6043-51.

35.

Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3.

Ask K, Bonniaud P, Maass K, Eickelberg O, Margetts PJ, Warburton D, Groffen J, Gauldie J, Kolb M.

Int J Biochem Cell Biol. 2008;40(3):484-95. Epub 2007 Sep 6.

36.

Peritoneal dialysis, membranes and beyond.

Margetts PJ, Brimble KS.

Curr Opin Nephrol Hypertens. 2006 Nov;15(6):571-6. Review.

PMID:
17053469
37.

Adenovirus-based transient expression systems for peritoneal membrane research.

Hoff CM, Margetts PJ.

Perit Dial Int. 2006 Sep-Oct;26(5):547-58. Review.

PMID:
16973508
38.

Meta-analysis: peritoneal membrane transport, mortality, and technique failure in peritoneal dialysis.

Brimble KS, Walker M, Margetts PJ, Kundhal KK, Rabbat CG.

J Am Soc Nephrol. 2006 Sep;17(9):2591-8. Epub 2006 Aug 2.

39.

TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis.

Bonniaud P, Margetts PJ, Ask K, Flanders K, Gauldie J, Kolb M.

J Immunol. 2005 Oct 15;175(8):5390-5.

40.

Transforming growth factor-beta: importance in long-term peritoneal membrane changes.

Margetts PJ, Oh KH, Kolb M.

Perit Dial Int. 2005 Feb;25 Suppl 3:S15-7. Review.

PMID:
16048248
41.

Benefit of continuous renal replacement therapy in subgroups of acutely ill patients: a retrospective analysis.

Gangji AS, Rabbat CG, Margetts PJ.

Clin Nephrol. 2005 Apr;63(4):267-75.

PMID:
15847253
42.

Cytokines and growth factors involved in peritoneal fibrosis of peritoneal dialysis patients.

Oh KH, Margetts PJ.

Int J Artif Organs. 2005 Feb;28(2):129-34. Review.

PMID:
15770592
43.

Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum.

Margetts PJ, Bonniaud P, Liu L, Hoff CM, Holmes CJ, West-Mays JA, Kelly MM.

J Am Soc Nephrol. 2005 Feb;16(2):425-36. Epub 2004 Dec 8.

44.

Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor.

Bonniaud P, Margetts PJ, Kolb M, Schroeder JA, Kapoun AM, Damm D, Murphy A, Chakravarty S, Dugar S, Higgins L, Protter AA, Gauldie J.

Am J Respir Crit Care Med. 2005 Apr 15;171(8):889-98. Epub 2004 Nov 24.

PMID:
15563636
45.

The gene transfer of soluble VEGF type I receptor (Flt-1) attenuates peritoneal fibrosis formation in mice but not soluble TGF-beta type II receptor gene transfer.

Motomura Y, Kanbayashi H, Khan WI, Deng Y, Blennerhassett PA, Margetts PJ, Gauldie J, Egashira K, Collins SM.

Am J Physiol Gastrointest Liver Physiol. 2005 Jan;288(1):G143-50. Epub 2004 Aug 5.

46.

Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis.

Bonniaud P, Kolb M, Galt T, Robertson J, Robbins C, Stampfli M, Lavery C, Margetts PJ, Roberts AB, Gauldie J.

J Immunol. 2004 Aug 1;173(3):2099-108.

47.

Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs.

Bonniaud P, Martin G, Margetts PJ, Ask K, Robertson J, Gauldie J, Kolb M.

Am J Respir Cell Mol Biol. 2004 Nov;31(5):510-6. Epub 2004 Jul 15.

PMID:
15256388
48.

Basic mechanisms and clinical implications of peritoneal fibrosis.

Margetts PJ, Bonniaud P.

Perit Dial Int. 2003 Nov-Dec;23(6):530-41. Review.

PMID:
14703193
49.
50.

Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis.

Bonniaud P, Margetts PJ, Kolb M, Haberberger T, Kelly M, Robertson J, Gauldie J.

Am J Respir Crit Care Med. 2003 Oct 1;168(7):770-8. Epub 2003 Jun 19.

PMID:
12816739

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