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Items: 25


Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases.

Akoumianakis I, Sanna F, Margaritis M, Badi I, Akawi N, Herdman L, Coutinho P, Fagan H, Antonopoulos AS, Oikonomou EK, Thomas S, Chiu AP, Chuaiphichai S, Kotanidis CP, Christodoulides C, Petrou M, Krasopoulos G, Sayeed R, Lv L, Hale A, Naeimi Kararoudi M, McNeill E, Douglas G, George S, Tousoulis D, Channon KM, Antoniades C.

Sci Transl Med. 2019 Sep 18;11(510). pii: eaav5055. doi: 10.1126/scitranslmed.aav5055.


Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.

Adlam D, Olson TM, Combaret N, Kovacic JC, Iismaa SE, Al-Hussaini A, O'Byrne MM, Bouajila S, Georges A, Mishra K, Braund PS, d'Escamard V, Huang S, Margaritis M, Nelson CP, de Andrade M, Kadian-Dodov D, Welch CA, Mazurkiewicz S, Jeunemaitre X; DISCO Consortium, Wong CMY, Giannoulatou E, Sweeting M, Muller D, Wood A, McGrath-Cadell L, Fatkin D, Dunwoodie SL, Harvey R, Holloway C, Empana JP, Jouven X; CARDIoGRAMPlusC4D Study Group, Olin JW, Gulati R, Tweet MS, Hayes SN, Samani NJ, Graham RM, Motreff P, Bouatia-Naji N.

J Am Coll Cardiol. 2019 Jan 8;73(1):58-66. doi: 10.1016/j.jacc.2018.09.085.


Improvement of home composting process of food waste using different minerals.

Margaritis M, Psarras K, Panaretou V, Thanos AG, Malamis D, Sotiropoulos A.

Waste Manag. 2018 Mar;73:87-100. doi: 10.1016/j.wasman.2017.12.009. Epub 2017 Dec 13.


Perivascular adipose tissue as an endocrine organ: the role of statins.

Sanna F, Margaritis M, Antoniades C.

Curr Pharm Des. 2017 Sep 26. doi: 10.2174/1381612823666170926133843. [Epub ahead of print]


Statins and oxidative stress in the cardiovascular system.

Margaritis M, Sanna F, Antoniades C.

Curr Pharm Des. 2017 Sep 26. doi: 10.2174/1381612823666170926130338. [Epub ahead of print]


Detecting human coronary inflammation by imaging perivascular fat.

Antonopoulos AS, Sanna F, Sabharwal N, Thomas S, Oikonomou EK, Herdman L, Margaritis M, Shirodaria C, Kampoli AM, Akoumianakis I, Petrou M, Sayeed R, Krasopoulos G, Psarros C, Ciccone P, Brophy CM, Digby J, Kelion A, Uberoi R, Anthony S, Alexopoulos N, Tousoulis D, Achenbach S, Neubauer S, Channon KM, Antoniades C.

Sci Transl Med. 2017 Jul 12;9(398). pii: eaal2658. doi: 10.1126/scitranslmed.aal2658.


Predictive value of telomere length on outcome following acute myocardial infarction: evidence for contrasting effects of vascular vs. blood oxidative stress.

Margaritis M, Sanna F, Lazaros G, Akoumianakis I, Patel S, Antonopoulos AS, Duke C, Herdman L, Psarros C, Oikonomou EK, Shirodaria C, Petrou M, Sayeed R, Krasopoulos G, Lee R, Tousoulis D, Channon KM, Antoniades C.

Eur Heart J. 2017 Nov 1;38(41):3094-3104. doi: 10.1093/eurheartj/ehx177.


Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-γ/Adiponectin Signalling.

Antonopoulos AS, Margaritis M, Verheule S, Recalde A, Sanna F, Herdman L, Psarros C, Nasrallah H, Coutinho P, Akoumianakis I, Brewer AC, Sayeed R, Krasopoulos G, Petrou M, Tarun A, Tousoulis D, Shah AM, Casadei B, Channon KM, Antoniades C.

Circ Res. 2016 Mar 4;118(5):842-55. doi: 10.1161/CIRCRESAHA.115.307856. Epub 2016 Jan 21.


Adiponectin as a link between type 2 diabetes and vascular NADPH oxidase activity in the human arterial wall: the regulatory role of perivascular adipose tissue.

Antonopoulos AS, Margaritis M, Coutinho P, Shirodaria C, Psarros C, Herdman L, Sanna F, De Silva R, Petrou M, Sayeed R, Krasopoulos G, Lee R, Digby J, Reilly S, Bakogiannis C, Tousoulis D, Kessler B, Casadei B, Channon KM, Antoniades C.

Diabetes. 2015 Jun;64(6):2207-19. doi: 10.2337/db14-1011. Epub 2014 Dec 31.


Reciprocal effects of systemic inflammation and brain natriuretic peptide on adiponectin biosynthesis in adipose tissue of patients with ischemic heart disease.

Antonopoulos AS, Margaritis M, Coutinho P, Digby J, Patel R, Psarros C, Ntusi N, Karamitsos TD, Lee R, De Silva R, Petrou M, Sayeed R, Demosthenous M, Bakogiannis C, Wordsworth PB, Tousoulis D, Neubauer S, Channon KM, Antoniades C.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2151-9. doi: 10.1161/ATVBAHA.114.303828. Epub 2014 Jul 24.


Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering.

Margaritis M, Channon KM, Antoniades C.

Antioxid Redox Signal. 2014 Mar 10;20(8):1198-215. doi: 10.1089/ars.2013.5430. Epub 2014 Jan 3. Review.


Interactions between vascular wall and perivascular adipose tissue reveal novel roles for adiponectin in the regulation of endothelial nitric oxide synthase function in human vessels.

Margaritis M, Antonopoulos AS, Digby J, Lee R, Reilly S, Coutinho P, Shirodaria C, Sayeed R, Petrou M, De Silva R, Jalilzadeh S, Demosthenous M, Bakogiannis C, Tousoulis D, Stefanadis C, Choudhury RP, Casadei B, Channon KM, Antoniades C.

Circulation. 2013 Jun 4;127(22):2209-21. doi: 10.1161/CIRCULATIONAHA.112.001133. Epub 2013 Apr 26.


Artifactual elevation of plasma sCD40L by residual platelets in patients with coronary artery disease.

Lee R, Antonopoulos AS, Alexopoulou Z, Margaritis M, Kharbanda RK, Choudhury RP, Antoniades C, Channon KM.

Int J Cardiol. 2013 Sep 30;168(2):1648-50. doi: 10.1016/j.ijcard.2013.03.019. Epub 2013 Apr 8. No abstract available.


Translating the effects of statins: from redox regulation to suppression of vascular wall inflammation.

Antonopoulos AS, Margaritis M, Shirodaria C, Antoniades C.

Thromb Haemost. 2012 Nov;108(5):840-8. doi: 10.1160/TH12-05-0337. Epub 2012 Aug 7. Review.


Nanomedicine for the prevention, treatment and imaging of atherosclerosis.

Psarros C, Lee R, Margaritis M, Antoniades C.

Nanomedicine. 2012 Sep;8 Suppl 1:S59-68. doi: 10.1016/j.nano.2012.05.006. Epub 2012 May 26. Review.


Evaluating oxidative stress in human cardiovascular disease: methodological aspects and considerations.

Lee R, Margaritis M, Channon KM, Antoniades C.

Curr Med Chem. 2012;19(16):2504-20. Review.


Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials.

Antonopoulos AS, Margaritis M, Lee R, Channon K, Antoniades C.

Curr Pharm Des. 2012;18(11):1519-30. Review.


Statins and vein graft failure in coronary bypass surgery.

Margaritis M, Channon KM, Antoniades C.

Curr Opin Pharmacol. 2012 Apr;12(2):172-80. doi: 10.1016/j.coph.2012.01.009. Epub 2012 Feb 10. Review.


Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease.

Cunnington C, Van Assche T, Shirodaria C, Kylintireas I, Lindsay AC, Lee JM, Antoniades C, Margaritis M, Lee R, Cerrato R, Crabtree MJ, Francis JM, Sayeed R, Ratnatunga C, Pillai R, Choudhury RP, Neubauer S, Channon KM.

Circulation. 2012 Mar 20;125(11):1356-66. doi: 10.1161/CIRCULATIONAHA.111.038919. Epub 2012 Feb 7.


Nanomedicine for the prevention, treatment and imaging of atherosclerosis.

Psarros C, Lee R, Margaritis M, Antoniades C.

Maturitas. 2012 Sep;73(1):52-60. doi: 10.1016/j.maturitas.2011.12.014. Epub 2012 Jan 18. Review.


Myocardial redox state predicts in-hospital clinical outcome after cardiac surgery effects of short-term pre-operative statin treatment.

Antoniades C, Demosthenous M, Reilly S, Margaritis M, Zhang MH, Antonopoulos A, Marinou K, Nahar K, Jayaram R, Tousoulis D, Bakogiannis C, Sayeed R, Triantafyllou C, Koumallos N, Psarros C, Miliou A, Stefanadis C, Channon KM, Casadei B.

J Am Coll Cardiol. 2012 Jan 3;59(1):60-70. doi: 10.1016/j.jacc.2011.08.062.


Statins in coronary artery bypass grafting surgery: lipid lowering and beyond.

Margaritis M, Antoniades C.

Expert Rev Cardiovasc Ther. 2012 Jan;10(1):5-8. doi: 10.1586/erc.11.174. No abstract available.


Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.

Antoniades C, Cunnington C, Antonopoulos A, Neville M, Margaritis M, Demosthenous M, Bendall J, Hale A, Cerrato R, Tousoulis D, Bakogiannis C, Marinou K, Toutouza M, Vlachopoulos C, Leeson P, Stefanadis C, Karpe F, Channon KM.

Circulation. 2011 Oct 25;124(17):1860-70. doi: 10.1161/CIRCULATIONAHA.111.029272. Epub 2011 Oct 3.


Adiponectin as a regulator of vascular redox state: therapeutic implications.

Antonopoulos AS, Lee R, Margaritis M, Antoniades C.

Recent Pat Cardiovasc Drug Discov. 2011 May;6(2):78-88. Review.


Effects of adult-onset choline deprivation on the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase in crucial rat brain regions.

Liapi C, Kyriakaki A, Zarros A, Al-Humadi H, Stolakis V, Gkrouzman E, Anifantaki F, Skandali N, Margaritis M, Tsakiris S.

Food Chem Toxicol. 2009 Jan;47(1):82-5. doi: 10.1016/j.fct.2008.10.012. Epub 2008 Oct 17.


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