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Items: 15

1.

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM.

Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9.

2.

Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation in Saccharomyces cerevisiae.

Segura-Wang M, Onishi-Seebacher M, Stütz AM, Mardin BR, Korbel JO.

G3 (Bethesda). 2017 Oct 5;7(10):3269-3279. doi: 10.1534/g3.117.300165.

3.

Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation.

Buccitelli C, Salgueiro L, Rowald K, Sotillo R, Mardin BR, Korbel JO.

Genome Res. 2017 Apr;27(4):501-511. doi: 10.1101/gr.212225.116. Epub 2017 Mar 20.

4.

Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.

Weischenfeldt J, Dubash T, Drainas AP, Mardin BR, Chen Y, Stütz AM, Waszak SM, Bosco G, Halvorsen AR, Raeder B, Efthymiopoulos T, Erkek S, Siegl C, Brenner H, Brustugun OT, Dieter SM, Northcott PA, Petersen I, Pfister SM, Schneider M, Solberg SK, Thunissen E, Weichert W, Zichner T, Thomas R, Peifer M, Helland A, Ball CR, Jechlinger M, Sotillo R, Glimm H, Korbel JO.

Nat Genet. 2017 Jan;49(1):65-74. doi: 10.1038/ng.3722. Epub 2016 Nov 21.

5.

Immortalization capacity of HPV types is inversely related to chromosomal instability.

Schütze DM, Krijgsman O, Snijders PJ, Ylstra B, Weischenfeldt J, Mardin BR, Stütz AM, Korbel JO, de Winter JP, Meijer CJ, Quint WG, Bosch L, Wilting SM, Steenbergen RD.

Oncotarget. 2016 Jun 21;7(25):37608-37621. doi: 10.18632/oncotarget.8058.

6.

Using large-scale genome variation cohorts to decipher the molecular mechanism of cancer.

Habermann N, Mardin BR, Yakneen S, Korbel JO.

C R Biol. 2016 Jul-Aug;339(7-8):308-13. doi: 10.1016/j.crvi.2016.05.008. Epub 2016 Jun 21. Review.

PMID:
27342254
7.

Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth.

Rowald K, Mantovan M, Passos J, Buccitelli C, Mardin BR, Korbel JO, Jechlinger M, Sotillo R.

Cell Rep. 2016 Jun 21;15(12):2679-91. doi: 10.1016/j.celrep.2016.05.048. Epub 2016 Jun 9.

8.

Identification of ZCCHC8 as fusion partner of ROS1 in a case of congenital glioblastoma multiforme with a t(6;12)(q21;q24.3).

Coccé MC, Mardin BR, Bens S, Stütz AM, Lubieniecki F, Vater I, Korbel JO, Siebert R, Alonso CN, Gallego MS.

Genes Chromosomes Cancer. 2016 Sep;55(9):677-87. doi: 10.1002/gcc.22369. Epub 2016 Jun 23.

PMID:
27121553
9.

A cell-based model system links chromothripsis with hyperploidy.

Mardin BR, Drainas AP, Waszak SM, Weischenfeldt J, Isokane M, Stütz AM, Raeder B, Efthymiopoulos T, Buccitelli C, Segura-Wang M, Northcott P, Pfister SM, Lichter P, Ellenberg J, Korbel JO.

Mol Syst Biol. 2015 Sep 28;11(9):828. doi: 10.15252/msb.20156505.

10.

Separate to operate: control of centrosome positioning and separation.

Agircan FG, Schiebel E, Mardin BR.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650). pii: 20130461. doi: 10.1098/rstb.2013.0461. Review.

11.

EGF-induced centrosome separation promotes mitotic progression and cell survival.

Mardin BR, Isokane M, Cosenza MR, Krämer A, Ellenberg J, Fry AM, Schiebel E.

Dev Cell. 2013 May 13;25(3):229-40. doi: 10.1016/j.devcel.2013.03.012. Epub 2013 May 2.

12.

Tandem fluorescent protein timers for in vivo analysis of protein dynamics.

Khmelinskii A, Keller PJ, Bartosik A, Meurer M, Barry JD, Mardin BR, Kaufmann A, Trautmann S, Wachsmuth M, Pereira G, Huber W, Schiebel E, Knop M.

Nat Biotechnol. 2012 Jun 24;30(7):708-14. doi: 10.1038/nbt.2281.

PMID:
22729030
13.

Breaking the ties that bind: new advances in centrosome biology.

Mardin BR, Schiebel E.

J Cell Biol. 2012 Apr 2;197(1):11-8. doi: 10.1083/jcb.201108006. Review.

14.

Plk1 controls the Nek2A-PP1γ antagonism in centrosome disjunction.

Mardin BR, Agircan FG, Lange C, Schiebel E.

Curr Biol. 2011 Jul 12;21(13):1145-51. doi: 10.1016/j.cub.2011.05.047. Epub 2011 Jun 30.

15.

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction.

Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM, Schiebel E.

Nat Cell Biol. 2010 Dec;12(12):1166-76. doi: 10.1038/ncb2120. Epub 2010 Nov 14.

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