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Items: 47

1.

Identification of Novel Predictive Biomarkers for Endometrial Malignancies: N-Acylethanolamines.

Ayakannu T, Taylor AH, Marczylo TH, Maccarrone M, Konje JC.

Front Oncol. 2019 Jun 11;9:430. doi: 10.3389/fonc.2019.00430. eCollection 2019.

2.

New Insights of Uterine Leiomyoma Pathogenesis: Endocannabinoid System.

Ayakannu T, Taylor AH, Marczylo TH, Konje JC.

Med Sci Monit Basic Res. 2019 Mar 7;25:76-87. doi: 10.12659/MSMBR.914019.

3.

Relationship between seminal plasma levels of anandamide congeners palmitoylethanolamide and oleoylethanolamide and semen quality.

Amoako AA, Marczylo TH, Elson J, Taylor AH, Willets JM, Konje JC.

Fertil Steril. 2014 Nov;102(5):1260-7. doi: 10.1016/j.fertnstert.2014.07.767. Epub 2014 Sep 8.

PMID:
25212838
4.

The effect of mifepristone (RU486) on the endocannabinoid system in human plasma and first-trimester trophoblast of women undergoing termination of pregnancy.

Karasu T, Marczylo TH, Marczylo EL, Taylor AH, Oloto E, Konje JC.

J Clin Endocrinol Metab. 2014 Mar;99(3):871-80. doi: 10.1210/jc.2013-2922. Epub 2013 Jan 1.

PMID:
24423290
5.

The endocannabinoid system and sex steroid hormone-dependent cancers.

Ayakannu T, Taylor AH, Marczylo TH, Willets JM, Konje JC.

Int J Endocrinol. 2013;2013:259676. doi: 10.1155/2013/259676. Epub 2013 Nov 27. Review.

6.

Plasma anandamide and related n-acylethanolamide levels are not elevated in pregnancies complicated by hyperemesis gravidarum.

Gebeh AK, Willets JM, Marczylo TH, Konje JC.

J Matern Fetal Neonatal Med. 2014 Jun;27(9):954-9. doi: 10.3109/14767058.2013.847413. Epub 2013 Oct 22.

PMID:
24117326
7.

Anandamide produced by Ca(2+)-insensitive enzymes induces excitation in primary sensory neurons.

Varga A, Jenes A, Marczylo TH, Sousa-Valente J, Chen J, Austin J, Selvarajah S, Piscitelli F, Andreou AP, Taylor AH, Kyle F, Yaqoob M, Brain S, White JP, Csernoch L, Di Marzo V, Buluwela L, Nagy I.

Pflugers Arch. 2014 Jul;466(7):1421-35. doi: 10.1007/s00424-013-1360-7. Epub 2013 Oct 10.

8.

Anandamide levels fluctuate in the bovine oviduct during the oestrous cycle.

Gervasi MG, Marczylo TH, Lam PM, Rana S, Franchi AM, Konje JC, Perez-Martinez S.

PLoS One. 2013 Aug 16;8(8):e72521. doi: 10.1371/journal.pone.0072521. eCollection 2013.

9.

Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia.

Amoako AA, Marczylo TH, Marczylo EL, Elson J, Willets JM, Taylor AH, Konje JC.

Hum Reprod. 2013 Aug;28(8):2058-66. doi: 10.1093/humrep/det232. Epub 2013 May 21.

PMID:
23697839
10.

Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity.

Gebeh AK, Willets JM, Bari M, Hirst RA, Marczylo TH, Taylor AH, Maccarrone M, Konje JC.

J Clin Endocrinol Metab. 2013 Mar;98(3):1226-34. doi: 10.1210/jc.2012-3390. Epub 2013 Jan 31.

PMID:
23372171
11.

Impact of reference gene selection for type 2 cannabinoid receptor gene expression studies in human spermatozoa.

Amoako AA, Gebeh AK, Marczylo EL, Willets JM, Elson J, Marczylo TH, Konje JC.

Andrologia. 2013 Aug;45(4):278-84. doi: 10.1111/and.12006. Epub 2012 Aug 29.

PMID:
22928818
12.

Dietary intake of rosmarinic acid by Apc(Min) mice, a model of colorectal carcinogenesis: levels of parent agent in the target tissue and effect on adenoma development.

Karmokar A, Marczylo TH, Cai H, Steward WP, Gescher AJ, Brown K.

Mol Nutr Food Res. 2012 May;56(5):775-83. doi: 10.1002/mnfr.201100617.

PMID:
22648624
13.

Characterisation of the endocannabinoid system in rat haemochorial placenta.

Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Konje JC, Teixeira NA.

Reprod Toxicol. 2012 Nov;34(3):347-56. doi: 10.1016/j.reprotox.2012.05.036. Epub 2012 May 18.

PMID:
22613199
14.

Rapid measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine in human biological matrices using ultra-high-performance liquid chromatography-tandem mass spectrometry.

Lam PM, Mistry V, Marczylo TH, Konje JC, Evans MD, Cooke MS.

Free Radic Biol Med. 2012 May 15;52(10):2057-63. doi: 10.1016/j.freeradbiomed.2012.03.004. Epub 2012 Apr 15.

15.

Diagnostic accuracy of maternal serum macrophage inhibitory cytokine-1 and pregnancy-associated plasma protein-A at 6-10 weeks of gestation to predict miscarriage.

Tong S, Ngian GL, Onwude JL, Permezel M, Saglam B, Hay S, Konje JC, Marczylo TH, Fleming G, Walker SP, Lappas M.

Obstet Gynecol. 2012 May;119(5):1000-8. doi: 10.1097/AOG.0b013e3182518fd3.

PMID:
22525911
16.

Smoking induces differential miRNA expression in human spermatozoa: a potential transgenerational epigenetic concern?

Marczylo EL, Amoako AA, Konje JC, Gant TW, Marczylo TH.

Epigenetics. 2012 May;7(5):432-9. doi: 10.4161/epi.19794. Epub 2012 May 1.

PMID:
22441141
17.

Characterization of the endocannabinoid system, CB(1) receptor signalling and desensitization in human myometrium.

Brighton PJ, Marczylo TH, Rana S, Konje JC, Willets JM.

Br J Pharmacol. 2011 Nov;164(5):1479-94. doi: 10.1111/j.1476-5381.2011.01425.x.

18.

Anthocyanin-rich extracts suppress the DNA-damaging effects of topoisomerase poisons in human colon cancer cells.

Esselen M, Fritz J, Hutter M, Teller N, Baechler S, Boettler U, Marczylo TH, Gescher AJ, Marko D.

Mol Nutr Food Res. 2011 May;55 Suppl 1:S143-53. doi: 10.1002/mnfr.201000315. Epub 2011 Jan 31.

PMID:
21280204
19.

The role of sex steroid hormones, cytokines and the endocannabinoid system in female fertility.

Karasu T, Marczylo TH, Maccarrone M, Konje JC.

Hum Reprod Update. 2011 May-Jun;17(3):347-61. doi: 10.1093/humupd/dmq058. Epub 2011 Jan 12. Review.

PMID:
21227997
20.

Quantitative analysis of anandamide and related acylethanolamides in human seminal plasma by ultra performance liquid chromatography tandem mass spectrometry.

Amoako AA, Marczylo TH, Lam PM, Willets JM, Derry A, Elson J, Konje JC.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Dec 1;878(31):3231-7. doi: 10.1016/j.jchromb.2010.09.024. Epub 2010 Oct 1.

PMID:
21056015
21.

Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry.

Lam PM, Marczylo TH, Konje JC.

Anal Bioanal Chem. 2010 Nov;398(5):2089-97. doi: 10.1007/s00216-010-4103-z. Epub 2010 Sep 12.

PMID:
20835819
22.

From Fertilisation to Implantation in Mammalian Pregnancy-Modulation of Early Human Reproduction by the Endocannabinoid System.

Bambang KN, Karasu T, Gebeh A, Taylor AH, Marczylo TH, Lam P, Willets JM, Konje JC.

Pharmaceuticals (Basel). 2010 Sep 2;3(9):2910-2929. Review.

23.

The endocannabinoid 2-arachidonoylglycerol (2-AG) and metabolizing enzymes during rat fetoplacental development: a role in uterine remodelling.

Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Bell SC, Konje JC, Teixeira NA.

Int J Biochem Cell Biol. 2010 Nov;42(11):1884-92. doi: 10.1016/j.biocel.2010.08.006. Epub 2010 Aug 19.

PMID:
20727980
24.

N-acylethanolamine levels and expression of their metabolizing enzymes during pregnancy.

Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Konje JC, Bell SC, Teixeira NA.

Endocrinology. 2010 Aug;151(8):3965-74. doi: 10.1210/en.2009-1424. Epub 2010 Jun 9.

PMID:
20534733
25.

The plasma levels of the endocannabinoid, anandamide, increase with the induction of labour.

Nallendran V, Lam PM, Marczylo TH, Bankart MJ, Taylor AH, Taylor DJ, Konje JC.

BJOG. 2010 Jun;117(7):863-9. doi: 10.1111/j.1471-0528.2010.02555.x. Epub 2010 Apr 20.

26.

Anthocyanin-rich red grape extract impedes adenoma development in the Apc(Min) mouse: pharmacodynamic changes and anthocyanin levels in the murine biophase.

Cai H, Marczylo TH, Teller N, Brown K, Steward WP, Marko D, Gescher AJ.

Eur J Cancer. 2010 Mar;46(4):811-7. doi: 10.1016/j.ejca.2009.12.017. Epub 2010 Jan 7.

PMID:
20060287
27.

Anandamide levels in human female reproductive tissues: solid-phase extraction and measurement by ultraperformance liquid chromatography tandem mass spectrometry.

Marczylo TH, Lam PM, Amoako AA, Konje JC.

Anal Biochem. 2010 May 15;400(2):155-62. doi: 10.1016/j.ab.2009.12.025. Epub 2009 Dec 22.

PMID:
20026294
28.

Pilot study of oral anthocyanins for colorectal cancer chemoprevention.

Thomasset S, Berry DP, Cai H, West K, Marczylo TH, Marsden D, Brown K, Dennison A, Garcea G, Miller A, Hemingway D, Steward WP, Gescher AJ.

Cancer Prev Res (Phila). 2009 Jul;2(7):625-33. doi: 10.1158/1940-6207.CAPR-08-0201.

29.

Pharmacokinetics and metabolism of the putative cancer chemopreventive agent cyanidin-3-glucoside in mice.

Marczylo TH, Cooke D, Brown K, Steward WP, Gescher AJ.

Cancer Chemother Pharmacol. 2009 Nov;64(6):1261-8. doi: 10.1007/s00280-009-0996-7. Epub 2009 Apr 11.

PMID:
19363608
30.

Suppression of the kinase activity of receptor tyrosine kinases by anthocyanin-rich mixtures extracted from bilberries and grapes.

Teller N, Thiele W, Marczylo TH, Gescher AJ, Boettler U, Sleeman J, Marko D.

J Agric Food Chem. 2009 Apr 22;57(8):3094-101. doi: 10.1021/jf803094a.

PMID:
19323506
31.

Rapid analysis of curcumin and curcumin metabolites in rat biomatrices using a novel ultraperformance liquid chromatography (UPLC) method.

Marczylo TH, Steward WP, Gescher AJ.

J Agric Food Chem. 2009 Feb 11;57(3):797-803. doi: 10.1021/jf803038f.

PMID:
19152267
32.

Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.

Warrilow AG, Jackson CJ, Parker JE, Marczylo TH, Kelly DE, Lamb DC, Kelly SL.

Antimicrob Agents Chemother. 2009 Mar;53(3):1157-64. doi: 10.1128/AAC.01237-08. Epub 2008 Dec 15.

33.

A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices.

Marczylo TH, Lam PM, Nallendran V, Taylor AH, Konje JC.

Anal Biochem. 2009 Jan 1;384(1):106-13. doi: 10.1016/j.ab.2008.08.040. Epub 2008 Sep 18.

PMID:
18823934
34.

Ultra performance liquid chromatography tandem mass spectrometry method for the measurement of anandamide in human plasma.

Lam PM, Marczylo TH, El-Talatini M, Finney M, Nallendran V, Taylor AH, Konje JC.

Anal Biochem. 2008 Sep 15;380(2):195-201. doi: 10.1016/j.ab.2008.05.033. Epub 2008 May 27.

PMID:
18555789
35.

Breast cancer prevention by green tea catechins and black tea theaflavins in the C3(1) SV40 T,t antigen transgenic mouse model is accompanied by increased apoptosis and a decrease in oxidative DNA adducts.

Kaur S, Greaves P, Cooke DN, Edwards R, Steward WP, Gescher AJ, Marczylo TH.

J Agric Food Chem. 2007 May 2;55(9):3378-85. Epub 2007 Apr 4.

PMID:
17407311
36.

A review of phase III clinical trials of prostate cancer chemoprevention.

Thorpe JF, Jain S, Marczylo TH, Gescher AJ, Steward WP, Mellon JK.

Ann R Coll Surg Engl. 2007 Apr;89(3):207-11. Review.

37.

Quantitation of silibinin, a putative cancer chemopreventive agent derived from milk thistle (Silybum marianum), in human plasma by high-performance liquid chromatography and identification of possible metabolites.

Hoh CS, Boocock DJ, Marczylo TH, Brown VA, Cai H, Steward WP, Berry DP, Gescher AJ.

J Agric Food Chem. 2007 Apr 4;55(7):2532-5. Epub 2007 Mar 14.

PMID:
17355141
38.

Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography.

Boocock DJ, Patel KR, Faust GE, Normolle DP, Marczylo TH, Crowell JA, Brenner DE, Booth TD, Gescher A, Steward WP.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Apr 1;848(2):182-7. Epub 2006 Nov 9.

39.

Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine.

Marczylo TH, Verschoyle RD, Cooke DN, Morazzoni P, Steward WP, Gescher AJ.

Cancer Chemother Pharmacol. 2007 Jul;60(2):171-7. Epub 2006 Oct 19.

PMID:
17051370
40.

Development of analyses by high-performance liquid chromatography and liquid chromatography/tandem mass spectrometry of bilberry (Vaccinium myrtilus) anthocyanins in human plasma and urine.

Cooke DN, Thomasset S, Boocock DJ, Schwarz M, Winterhalter P, Steward WP, Gescher AJ, Marczylo TH.

J Agric Food Chem. 2006 Sep 20;54(19):7009-13.

PMID:
16968056
41.
42.

Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance.

Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, Hewitt HR, Marczylo TH, Morgan B, Hemingway D, Plummer SM, Pirmohamed M, Gescher AJ, Steward WP.

Clin Cancer Res. 2004 Oct 15;10(20):6847-54.

43.

Conservation and cloning of CYP51: a sterol 14 alpha-demethylase from Mycobacterium smegmatis.

Jackson CJ, Lamb DC, Marczylo TH, Parker JE, Manning NL, Kelly DE, Kelly SL.

Biochem Biophys Res Commun. 2003 Feb 7;301(2):558-63.

PMID:
12565899
44.

A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily.

Jackson CJ, Lamb DC, Marczylo TH, Warrilow AG, Manning NJ, Lowe DJ, Kelly DE, Kelly SL.

J Biol Chem. 2002 Dec 6;277(49):46959-65. Epub 2002 Sep 13.

45.

Preventive effects of anthraquinone food pigments on the DNA damage induced by carcinogens in Drosophila.

Takahashi E, Marczylo TH, Watanabe T, Nagai S, Hayatsu H, Negishi T.

Mutat Res. 2001 Sep 1;480-481:139-45.

PMID:
11506807
46.

Protection against the bacterial mutagenicity of heterocyclic amines by purpurin, a natural anthraquinone pigment.

Marczylo TH, Hayatsu T, Arimoto-Kobayashi S, Tada M, Fujita K, Kamataki T, Nakayama K, Hayatsu H.

Mutat Res. 1999 Aug 18;444(2):451-61.

PMID:
10521685
47.

Effects of sublethal exposure to an organophosphate on the flying performance of captive starlings.

Fryday SL, Hart AD, Marczylo TH.

Bull Environ Contam Toxicol. 1995 Sep;55(3):366-73. No abstract available.

PMID:
8520142

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