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Thyrotropin Causes Dose-dependent Biphasic Regulation of cAMP Production Mediated by Gs and Gi/o Proteins.
Neumann S, Malik SS, Marcus-Samuels B, Eliseeva E, Jang D, Klubo-Gwiezdzinska J, Krieger CC, Gershengorn MC.
Mol Pharmacol. 2020 Jan;97(1):2-8. doi: 10.1124/mol.119.117382. Epub 2019 Nov 8.
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Evidence That Graves' Ophthalmopathy Immunoglobulins Do Not Directly Activate IGF-1 Receptors.
Marcus-Samuels B, Krieger CC, Boutin A, Kahaly GJ, Neumann S, Gershengorn MC.
Thyroid. 2018 May;28(5):650-655. doi: 10.1089/thy.2018.0089. Epub 2018 Apr 30.
TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis.
Krieger CC, Neumann S, Marcus-Samuels B, Gershengorn MC.
Thyroid. 2017 May;27(5):746-747. doi: 10.1089/thy.2017.0105. Epub 2017 Mar 27. No abstract available.
Thyrotropin Stimulates Differentiation Not Proliferation of Normal Human Thyrocytes in Culture.
Morgan SJ, Neumann S, Marcus-Samuels B, Gershengorn MC.
Front Endocrinol (Lausanne). 2016 Dec 26;7:168. doi: 10.3389/fendo.2016.00168. eCollection 2016.
Thyrotropin and Insulin-Like Growth Factor 1 Receptor Crosstalk Upregulates Sodium-Iodide Symporter Expression in Primary Cultures of Human Thyrocytes.
Thyroid. 2016 Dec;26(12):1794-1803. Epub 2016 Oct 18.
TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis.
Krieger CC, Place RF, Bevilacqua C, Marcus-Samuels B, Abel BS, Skarulis MC, Kahaly GJ, Neumann S, Gershengorn MC.
J Clin Endocrinol Metab. 2016 Jun;101(6):2340-7. doi: 10.1210/jc.2016-1315. Epub 2016 Apr 4.
Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobins.
Krieger CC, Neumann S, Place RF, Marcus-Samuels B, Gershengorn MC.
J Clin Endocrinol Metab. 2015 Mar;100(3):1071-7. doi: 10.1210/jc.2014-3566. Epub 2014 Dec 8.
Persistent cAMP signaling by thyrotropin (TSH) receptors is not dependent on internalization.
Neumann S, Geras-Raaka E, Marcus-Samuels B, Gershengorn MC.
FASEB J. 2010 Oct;24(10):3992-9. doi: 10.1096/fj.10-161745. Epub 2010 Jun 10.
Human islet-derived precursor cells are mesenchymal stromal cells that differentiate and mature to hormone-expressing cells in vivo.
Davani B, Ikonomou L, Raaka BM, Geras-Raaka E, Morton RA, Marcus-Samuels B, Gershengorn MC.
Stem Cells. 2007 Dec;25(12):3215-22. Epub 2007 Sep 27.
Trypsin and thrombin accelerate aggregation of human endocrine pancreas precursor cells.
Wei C, Geras-Raaka E, Marcus-Samuels B, Oron Y, Gershengorn MC.
J Cell Physiol. 2006 Feb;206(2):322-8.
Epithelial-to-mesenchymal transition generates proliferative human islet precursor cells.
Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM.
Science. 2004 Dec 24;306(5705):2261-4. Epub 2004 Nov 25.
Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates.
Hardikar AA, Marcus-Samuels B, Geras-Raaka E, Raaka BM, Gershengorn MC.
Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7117-22. Epub 2003 May 30.
Opposite effects of background genotype on muscle and liver insulin sensitivity of lipoatrophic mice. Role of triglyceride clearance.
Colombo C, Haluzik M, Cutson JJ, Dietz KR, Marcus-Samuels B, Vinson C, Gavrilova O, Reitman ML.
J Biol Chem. 2003 Feb 7;278(6):3992-9. Epub 2002 Nov 26.
Adrenalectomy improves diabetes in A-ZIP/F-1 lipoatrophic mice by increasing both liver and muscle insulin sensitivity.
Haluzik M, Dietz KR, Kim JK, Marcus-Samuels B, Shulman GI, Gavrilova O, Reitman ML.
Diabetes. 2002 Jul;51(7):2113-8.
Characterization of adiposity and metabolism in Lmna-deficient mice.
Cutler DA, Sullivan T, Marcus-Samuels B, Stewart CL, Reitman ML.
Biochem Biophys Res Commun. 2002 Mar 1;291(3):522-7.
Leptin and its role in pregnancy and fetal development--an overview.
Reitman ML, Bi S, Marcus-Samuels B, Gavrilova O.
Biochem Soc Trans. 2001 May;29(Pt 2):68-72. Review.
Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones.
Chao L, Marcus-Samuels B, Mason MM, Moitra J, Vinson C, Arioglu E, Gavrilova O, Reitman ML.
J Clin Invest. 2000 Nov;106(10):1221-8.
Lack of responses to a beta3-adrenergic agonist in lipoatrophic A-ZIP/F-1 mice.
Gavrilova O, Marcus-Samuels B, Reitman ML.
Diabetes. 2000 Nov;49(11):1910-6.
Transgenic mice lacking white fat: models for understanding human lipoatrophic diabetes.
Reitman ML, Mason MM, Moitra J, Gavrilova O, Marcus-Samuels B, Eckhaus M, Vinson C.
Ann N Y Acad Sci. 1999 Nov 18;892:289-96. Review.
Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3.
Gong DW, Monemdjou S, Gavrilova O, Leon LR, Marcus-Samuels B, Chou CJ, Everett C, Kozak LP, Li C, Deng C, Harper ME, Reitman ML.
J Biol Chem. 2000 May 26;275(21):16251-7.
Leptin and diabetes in lipoatrophic mice.
Gavrilova O, Marcus-Samuels B, Leon LR, Vinson C, Reitman ML.
Nature. 2000 Feb 24;403(6772):850; discussion 850-1. No abstract available.
Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice.
Gavrilova O, Marcus-Samuels B, Graham D, Kim JK, Shulman GI, Castle AL, Vinson C, Eckhaus M, Reitman ML.
J Clin Invest. 2000 Feb;105(3):271-8.
Torpor in mice is induced by both leptin-dependent and -independent mechanisms.
Gavrilova O, Leon LR, Marcus-Samuels B, Mason MM, Castle AL, Refetoff S, Vinson C, Reitman ML.
Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14623-8.
Life without white fat: a transgenic mouse.
Moitra J, Mason MM, Olive M, Krylov D, Gavrilova O, Marcus-Samuels B, Feigenbaum L, Lee E, Aoyama T, Eckhaus M, Reitman ML, Vinson C.
Genes Dev. 1998 Oct 15;12(20):3168-81.
Hyperleptinemia of pregnancy associated with the appearance of a circulating form of the leptin receptor.
Gavrilova O, Barr V, Marcus-Samuels B, Reitman M.
J Biol Chem. 1997 Nov 28;272(48):30546-51.
Mutagenesis of lysine 460 in the human insulin receptor. Effects upon receptor recycling and cooperative interactions among binding sites.
Kadowaki H, Kadowaki T, Cama A, Marcus-Samuels B, Rovira A, Bevins CL, Taylor SI.
J Biol Chem. 1990 Dec 5;265(34):21285-96.
Mutations in the insulin receptor gene in genetic forms of insulin resistance.
Taylor SI, Kadowaki T, Accili D, Cama A, Kadowaki H, McKeon C, Moncada V, Marcus-Samuels B, Bevins C, Ojamaa K, et al.
Recent Prog Horm Res. 1990;46:185-213; discussion 213-7. Review. No abstract available.
Atypical antiinsulin receptor antibodies in a patient with type B insulin resistance and scleroderma.
Bloise W, Wajchenberg BL, Moncada VY, Marcus-Samuels B, Taylor SI.
J Clin Endocrinol Metab. 1989 Jan;68(1):227-31.
Immunological abnormalities in insulin receptors on cultured EBV-transformed lymphocytes from insulin-resistant patient with leprechaunism.
Cama A, Marcus-Samuels B, Taylor SI.
Diabetes. 1988 Jul;37(7):982-8.
Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance.
Kadowaki T, Bevins CL, Cama A, Ojamaa K, Marcus-Samuels B, Kadowaki H, Beitz L, McKeon C, Taylor SI.
Science. 1988 May 6;240(4853):787-90.
Insulin stimulates phosphorylation of a 120-kDa glycoprotein substrate (pp120) for the receptor-associated protein kinase in intact H-35 hepatoma cells.
Perrotti N, Accili D, Marcus-Samuels B, Rees-Jones RW, Taylor SI.
Proc Natl Acad Sci U S A. 1987 May;84(10):3137-40.
Receptors for insulin and growth hormone on lymphoid cells.
Lesniak MA, Hedo JA, Grunberger G, Marcus-Samuels B, Roth J, Gorden P.
Methods Enzymol. 1987;150:701-23. No abstract available.
Genetics of the insulin receptor defect in a patient with extreme insulin resistance.
Taylor SI, Marcus-Samuels B, Ryan-Young J, Leventhal S, Elders MJ.
J Clin Endocrinol Metab. 1986 Jun;62(6):1130-5.
Assay of antibodies directed against cell surface receptors.
Taylor SI, Underhill LH, Marcus-Samuels B.
Methods Enzymol. 1985;109:656-67. No abstract available.
Binding of insulin to its receptor impairs recognition by monoclonal anti-insulin antibodies.
Taylor SI, Schroer JA, Marcus-Samuels B, McElduff A, Bender TP.
Diabetes. 1984 Aug;33(8):778-84.
Anti-receptor antibodies mimic the effect of insulin to down-regulate insulin receptors in cultured human lymphoblastoid (IM-9) cells.
Taylor SI, Marcus-Samuels B.
J Clin Endocrinol Metab. 1984 Jan;58(1):182-6.
Hypoglycemia associated with antibodies to the insulin receptor.
Taylor SI, Grunberger G, Marcus-Samuels B, Underhill LH, Dons RF, Ryan J, Roddam RF, Rupe CE, Gorden P.
N Engl J Med. 1982 Dec 2;307(23):1422-6.
Receptor affinity and biological potency of thyroid hormones in thyrotropic cells.
Gershengorn MC, Geras E, Marcus-Samuels BE, Rebecchi MJ.
Am J Physiol. 1979 Aug;237(2):E142-6.
Estrogens increase the number of thyrotropin-releasing hormone receptors on mammotropic cells in culture.
Gershengorn MC, Marcus-Samuels BE, Geras E.
Endocrinology. 1979 Jul;105(1):171-6.
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