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Items: 35

1.

Alternative splicing of the vitamin D receptor modulates target gene expression and promotes ligand-independent functions.

Annalora AJ, Jozic M, Marcus CB, Iversen PL.

Toxicol Appl Pharmacol. 2019 Feb 1;364:55-67. doi: 10.1016/j.taap.2018.12.009. Epub 2018 Dec 12.

PMID:
30552932
2.

A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors.

Annalora AJ, O'Neil S, Bushman JD, Summerton JE, Marcus CB, Iversen PL.

Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17.

3.

Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism.

Annalora AJ, Marcus CB, Iversen PL.

Drug Metab Dispos. 2017 Apr;45(4):375-389. doi: 10.1124/dmd.116.073254. Epub 2017 Feb 10. Review.

PMID:
28188297
4.

Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes.

Borland MG, Krishnan P, Lee C, Albrecht PP, Shan W, Bility MT, Marcus CB, Lin JM, Amin S, Gonzalez FJ, Perdew GH, Peters JM.

Carcinogenesis. 2014 Jul;35(7):1602-12. doi: 10.1093/carcin/bgu067. Epub 2014 Mar 17.

5.

Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation.

Hughes D, Guttenplan JB, Marcus CB, Subbaramaiah K, Dannenberg AJ.

Cancer Prev Res (Phila). 2008 Nov;1(6):485-93. doi: 10.1158/1940-6207.CAPR-08-0149.

6.

Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress.

Conway DE, Sakurai Y, Weiss D, Vega JD, Taylor WR, Jo H, Eskin SG, Marcus CB, McIntire LV.

Cardiovasc Res. 2009 Mar 1;81(4):669-77. doi: 10.1093/cvr/cvn360. Epub 2009 Jan 6.

7.

CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression.

Tang Y, Scheef EA, Wang S, Sorenson CM, Marcus CB, Jefcoate CR, Sheibani N.

Blood. 2009 Jan 15;113(3):744-54. doi: 10.1182/blood-2008-03-145219. Epub 2008 Nov 12.

8.

Evidence for an aryl hydrocarbon receptor-mediated cytochrome p450 autoregulatory pathway.

Chiaro CR, Patel RD, Marcus CB, Perdew GH.

Mol Pharmacol. 2007 Nov;72(5):1369-79. Epub 2007 Aug 24.

PMID:
17720764
9.

Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: insights into substrate specificity and membrane bound structure-function.

Annalora AJ, Bobrovnikov-Marjon E, Serda R, Pastuszyn A, Graham SE, Marcus CB, Omdahl JL.

Arch Biochem Biophys. 2007 Apr 15;460(2):262-73. Epub 2006 Dec 3.

10.

In vitro exposure to environmental tobacco smoke induces CYP1B1 expression in human luteinized granulosa cells.

Vidal JD, VandeVoort CA, Marcus CB, Lazarewicz NR, Conley AJ.

Reprod Toxicol. 2006 Nov;22(4):731-7. Epub 2006 Jun 18.

PMID:
16996243
11.

2,3,7,8-tetrachlorodibenzo-p-dioxin induces CYP1B1 expression in human luteinized granulosa cells.

Vidal JD, Vandevoort CA, Marcus CB, Lazarewicz NR, Conley AJ.

Arch Biochem Biophys. 2005 Jul 1;439(1):53-60.

PMID:
15953582
12.

Tobacco smoke induces CYP1B1 in the aerodigestive tract.

Port JL, Yamaguchi K, Du B, De Lorenzo M, Chang M, Heerdt PM, Kopelovich L, Marcus CB, Altorki NK, Subbaramaiah K, Dannenberg AJ.

Carcinogenesis. 2004 Nov;25(11):2275-81. Epub 2004 Aug 5.

PMID:
15297370
13.

Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity.

Annalora A, Bobrovnikova-Marjon E, Serda R, Lansing L, Chiu ML, Pastuszyn A, Iyer S, Marcus CB, Omdahl JL.

Arch Biochem Biophys. 2004 May 15;425(2):133-46.

PMID:
15111121
14.

Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies.

Doctrow SR, Huffman K, Marcus CB, Tocco G, Malfroy E, Adinolfi CA, Kruk H, Baker K, Lazarowych N, Mascarenhas J, Malfroy B.

J Med Chem. 2002 Sep 26;45(20):4549-58.

PMID:
12238934
15.

Digital toxicology education tools: education, training, case studies, and tutorials.

Sharpe JF, Eaton DL, Marcus CB.

Toxicology. 2001 Jan 12;157(1-2):141-52.

PMID:
11164980
16.

Differential induction of cytochrome P450 gene expression by 4n-alkyl-methylenedioxybenzenes in primary rat hepatocyte cultures.

Sidhu JS, Marcus CB, Parkinson A, Omiecinski CJ.

J Biochem Mol Toxicol. 1998;12(5):253-62.

PMID:
9664231
17.
18.
19.

Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.

Einolf HJ, Story WT, Marcus CB, Larsen MC, Jefcoate CR, Greenlee WF, Yagi H, Jerina DM, Amin S, Park SS, Gelboin HV, Baird WM.

Chem Res Toxicol. 1997 May;10(5):609-17.

PMID:
9168260
20.

Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy.

Doctrow SR, Huffman K, Marcus CB, Musleh W, Bruce A, Baudry M, Malfroy B.

Adv Pharmacol. 1997;38:247-69. Review. No abstract available.

PMID:
8895812
21.

Cytochrome P450 1B1 expression in human malignant tumours.

Taylor MC, McKay JA, Murray GI, Greenlee WF, Marcus CB, Burke MD, Melvin WT.

Biochem Soc Trans. 1996 May;24(2):328S. No abstract available.

PMID:
8736986
22.

Differential expression of CYP1A1 and CYP1B1 in human breast cancer.

McKay JA, Murray GI, Ah-See AK, Greenlee WF, Marcus CB, Burke MD, Melvin WT.

Biochem Soc Trans. 1996 May;24(2):327S. No abstract available.

PMID:
8736985
23.

Expression of cytochrome P450 CYP1B1 in breast cancer.

McKay JA, Melvin WT, Ah-See AK, Ewen SW, Greenlee WF, Marcus CB, Burke MD, Murray GI.

FEBS Lett. 1995 Oct 30;374(2):270-2.

24.

Inhibition of benzo[a]pyrene metabolism by insulin, FITC-insulin and an FITC-insulin-antibody conjugate in the human hepatoma cell line HepG2.

Polzer RJ, Coffing SL, Marcus CB, Park SS, Gelboin HV, Baird WM.

Chem Biol Interact. 1995 Aug 18;97(3):307-18.

PMID:
7671346
26.

Effect of p-xylene inhalation on the bioactivation of bromobenzene in rat lung and liver.

Day BJ, DeNicola DB, Marcus CB, Carlson GP.

Fundam Appl Toxicol. 1992 Jul;19(1):50-6.

PMID:
1397801
27.

Effects of synthetic and naturally occurring flavonoids on metabolic activation of benzo[a]pyrene in hamster embryo cell cultures.

Chae YH, Ho DK, Cassady JM, Cook VM, Marcus CB, Baird WM.

Chem Biol Interact. 1992 Apr 15;82(2):181-93.

PMID:
1568269
29.

3-Methylindole-induced splenotoxicity: functional analysis of immune parameters and lymphocyte phenotyping by flow cytometry.

Updyke LW, Yoon HL, Robinson JP, Kiorpes AL, Marcus CB, Pfeifer RW.

Toxicol Appl Pharmacol. 1991 Jul;109(3):391-8.

PMID:
1853341
30.

3-Methylindole-induced splenotoxicity: biochemical mechanisms of cytotoxicity.

Updyke LW, Yoon HL, Kiorpes AL, Robinson JP, Pfeifer RW, Marcus CB.

Toxicol Appl Pharmacol. 1991 Jul;109(3):375-90.

PMID:
1853340
31.

Selective induction of cytochrome P450 isozymes in rat liver by 4-n-alkyl-methylenedioxybenzenes.

Marcus CB, Wilson NM, Jefcoate CR, Wilkinson CF, Omiecinski CJ.

Arch Biochem Biophys. 1990 Feb 15;277(1):8-16.

PMID:
2306127
32.

Selective expression of cytochrome P450 isozymes by 4-n-alkyl-methylenedioxybenzenes in rat lung cells.

Marcus CB, Wilson NM, Keith IM, Jefcoate CR, Omiecinski CJ.

Arch Biochem Biophys. 1990 Feb 15;277(1):17-25.

PMID:
2306118
33.

Selectivity in the binding of hydroxylated benzo[a]pyrene derivatives to purified cytochrome P-450c.

Turner CR, Marcus CB, Jefcoate CR.

Biochemistry. 1985 Sep 10;24(19):5124-30.

PMID:
4074683
34.

Binding of benzo[a]pyrene by purified cytochrome P-450c.

Marcus CB, Turner CR, Jefcoate CR.

Biochemistry. 1985 Sep 10;24(19):5115-23.

PMID:
4074682
35.

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