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Fast and accurate bacterial species identification in urine specimens using LC-MS/MS mass spectrometry and machine learning.

Roux-Dalvai F, Gotti C, Leclercq M, Hélie MC, Boissinot M, Arrey TN, Dauly C, Fournier F, Kelly I, Marcoux J, Bestman-Smith J, Bergeron MG, Droit A.

Mol Cell Proteomics. 2019 Oct 4. pii: mcp.TIR119.001559. doi: 10.1074/mcp.TIR119.001559. [Epub ahead of print]


Top-Down and Intact Protein Mass Spectrometry Data Visualization for Proteoform Analysis Using VisioProt-MS.

Lesne J, Bousquet MP, Marcoux J, Locard-Paulet M.

Bioinform Biol Insights. 2019 Aug 16;13:1177932219868223. doi: 10.1177/1177932219868223. eCollection 2019.


Combination Olaparib and Temozolomide in Relapsed Small-Cell Lung Cancer.

Farago AF, Yeap BY, Stanzione M, Hung YP, Heist RS, Marcoux JP, Zhong J, Rangachari D, Barbie DA, Phat S, Myers DT, Morris R, Kem M, Dubash TD, Kennedy EA, Digumarthy SR, Sequist LV, Hata AN, Maheswaran S, Haber DA, Lawrence MS, Shaw AT, Mino-Kenudson M, Dyson NJ, Drapkin BJ.

Cancer Discov. 2019 Oct;9(10):1372-1387. doi: 10.1158/2159-8290.CD-19-0582. Epub 2019 Aug 15.


HDX-Viewer: interactive 3D visualization of hydrogen-deuterium exchange data.

Bouyssié D, Lesne J, Locard-Paulet M, Albigot R, Burlet-Schiltz O, Marcoux J.

Bioinformatics. 2019 Jul 9. pii: btz550. doi: 10.1093/bioinformatics/btz550. [Epub ahead of print]


Antithrombotic agents and traumatic brain injury in the elderly population: hemorrhage patterns and outcomes.

Scotti P, Séguin C, Lo BWY, de Guise E, Troquet JM, Marcoux J.

J Neurosurg. 2019 Jul 5:1-10. doi: 10.3171/2019.4.JNS19252. [Epub ahead of print]


Publisher Correction: Structural insights into chaperone addiction of toxin-antitoxin systems.

Guillet V, Bordes P, Bon C, Marcoux J, Gervais V, Sala AJ, Dos Reis S, Slama N, Mares-Mejía I, Cirinesi AM, Maveyraud L, Genevaux P, Mourey L.

Nat Commun. 2019 Mar 7;10(1):1187. doi: 10.1038/s41467-019-09110-3.


Structural insights into chaperone addiction of toxin-antitoxin systems.

Guillet V, Bordes P, Bon C, Marcoux J, Gervais V, Sala AJ, Dos Reis S, Slama N, Mares-Mejía I, Cirinesi AM, Maveyraud L, Genevaux P, Mourey L.

Nat Commun. 2019 Feb 15;10(1):782. doi: 10.1038/s41467-019-08747-4. Erratum in: Nat Commun. 2019 Mar 7;10(1):1187.


Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding.

Trcka F, Durech M, Vankova P, Chmelik J, Martinkova V, Hausner J, Kadek A, Marcoux J, Klumpler T, Vojtesek B, Muller P, Man P.

Mol Cell Proteomics. 2019 Feb;18(2):320-337. doi: 10.1074/mcp.RA118.001044. Epub 2018 Nov 20.


Effect of Intrawound Vancomycin on Surgical Site Infections in Nonspinal Neurosurgical Procedures: A Systematic Review and Meta-Analysis.

Bokhari R, You E, Zeiler FA, Bakhaidar M, Bajunaid K, Lasry O, Baeesa S, Marcoux J.

World Neurosurg. 2019 Mar;123:409-417.e7. doi: 10.1016/j.wneu.2018.10.168. Epub 2018 Nov 2.


VisioProt-MS: interactive 2D maps from intact protein mass spectrometry.

Locard-Paulet M, Parra J, Albigot R, Mouton-Barbosa E, Bardi L, Burlet-Schiltz O, Marcoux J.

Bioinformatics. 2019 Feb 15;35(4):679-681. doi: 10.1093/bioinformatics/bty680.


Small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity represents a potential strategy for anticancer therapy.

Gervais V, Muller I, Mari PO, Mourcet A, Movellan KT, Ramos P, Marcoux J, Guillet V, Javaid S, Burlet-Schiltz O, Czaplicki G, Milon A, Giglia-Mari G.

J Biol Chem. 2018 Sep 28;293(39):14974-14988. doi: 10.1074/jbc.RA118.003444. Epub 2018 Aug 1.


Plasminogen activation triggers transthyretin amyloidogenesis in vitro.

Mangione PP, Verona G, Corazza A, Marcoux J, Canetti D, Giorgetti S, Raimondi S, Stoppini M, Esposito M, Relini A, Canale C, Valli M, Marchese L, Faravelli G, Obici L, Hawkins PN, Taylor GW, Gillmore JD, Pepys MB, Bellotti V.

J Biol Chem. 2018 Sep 14;293(37):14192-14199. doi: 10.1074/jbc.RA118.003990. Epub 2018 Jul 17.


Accuracy of Administrative Health Data for Surveillance of Traumatic Brain Injury: A Bayesian Latent Class Analysis.

Lasry O, Dendukuri N, Marcoux J, Buckeridge DL.

Epidemiology. 2018 Nov;29(6):876-884. doi: 10.1097/EDE.0000000000000888.


CT Perfusion to Guide Placement of Invasive Cerebral Perfusion Monitor in Subarachnoid Hemorrhage Induced Vasospasm.

Al-Jehani H, Marcoux J, Hadhiah K, Alabbas F, Angle M, Teitelbaum J.

Case Rep Neurol Med. 2018 Apr 4;2018:5162629. doi: 10.1155/2018/5162629. eCollection 2018.


Acute prediction of outcome and cognitive-communication impairments following traumatic brain injury: The influence of age, education and site of lesion.

Gauthier S, LeBlanc J, Seresova A, Laberge-Poirier A, A Correa J, Alturki AY, Marcoux J, Maleki M, Feyz M, de Guise E.

J Commun Disord. 2018 May - Jun;73:77-90. doi: 10.1016/j.jcomdis.2018.04.003. Epub 2018 Apr 14.


The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S.

Sbardella D, Tundo GR, Coletta A, Marcoux J, Koufogeorgou EI, Ciaccio C, Santoro AM, Milardi D, Grasso G, Cozza P, Bousquet-Dubouch MP, Marini S, Coletta M.

Cell Mol Life Sci. 2018 Sep;75(18):3441-3456. doi: 10.1007/s00018-018-2807-y. Epub 2018 Mar 28.


Frontal assessment battery (FAB) performance following traumatic brain injury hospitalized in an acute care setting.

Rojas N, Laguë-Beauvais M, Belisle A, Lamoureux J, AlSideiri G, Marcoux J, Maleki M, Alturki AY, Anchouche S, Alquraini H, Feyz M, de Guise E.

Appl Neuropsychol Adult. 2019 Jul-Aug;26(4):319-330. doi: 10.1080/23279095.2017.1422506. Epub 2018 Jan 19.


Early abnormal transient hyperemic response test can predict delayed ischemic neurologic deficit in subarachnoid hemorrhage.

Al-Jehani H, Angle M, Marcoux J, Teitelbaum J.

Crit Ultrasound J. 2018 Jan 4;10(1):1. doi: 10.1186/s13089-017-0079-7.


Rare Aggressive Calvarial Osteoblastoma with Dural Invasion.

Jacques L, Mousseau I, Al Hinai Q, Santos J, Nahal A, Marcoux J.

Cureus. 2017 Sep 30;9(9):e1733. doi: 10.7759/cureus.1733.


Epidemiology of recurrent traumatic brain injury in the general population: A systematic review.

Lasry O, Liu EY, Powell GA, Ruel-Laliberté J, Marcoux J, Buckeridge DL.

Neurology. 2017 Nov 21;89(21):2198-2209. doi: 10.1212/WNL.0000000000004671. Epub 2017 Oct 25. Review.


Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane.

Chiaradia L, Lefebvre C, Parra J, Marcoux J, Burlet-Schiltz O, Etienne G, Tropis M, Daffé M.

Sci Rep. 2017 Oct 9;7(1):12807. doi: 10.1038/s41598-017-12718-4.


The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.

Radu L, Schoenwetter E, Braun C, Marcoux J, Koelmel W, Schmitt DR, Kuper J, Cianférani S, Egly JM, Poterszman A, Kisker C.

Nucleic Acids Res. 2017 Oct 13;45(18):10872-10883. doi: 10.1093/nar/gkx743.


Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces.

Ambrose S, Housden NG, Gupta K, Fan J, White P, Yen HY, Marcoux J, Kleanthous C, Hopper JTS, Robinson CV.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14463-14468. doi: 10.1002/anie.201704849. Epub 2017 Sep 18.


Placement accuracy of external ventricular drain when comparing freehand insertion to neuronavigation guidance in severe traumatic brain injury.

AlAzri A, Mok K, Chankowsky J, Mullah M, Marcoux J.

Acta Neurochir (Wien). 2017 Aug;159(8):1399-1411. doi: 10.1007/s00701-017-3201-5. Epub 2017 May 29.


Traumatic Brain Injury in the Workplace.

Paci M, Infante-Rivard C, Marcoux J.

Can J Neurol Sci. 2017 Sep;44(5):518-524. doi: 10.1017/cjn.2017.43. Epub 2017 May 22.


A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.

Raimondi S, Porcari R, Mangione PP, Verona G, Marcoux J, Giorgetti S, Taylor GW, Ellmerich S, Ballico M, Zanini S, Pardon E, Al-Shawi R, Simons JP, Corazza A, Fogolari F, Leri M, Stefani M, Bucciantini M, Gillmore JD, Hawkins PN, Valli M, Stoppini M, Robinson CV, Steyaert J, Esposito G, Bellotti V.

Sci Rep. 2017 Apr 21;7:46711. doi: 10.1038/srep46711.


Identification of specific posttranslational O-mycoloylations mediating protein targeting to the mycomembrane.

Carel C, Marcoux J, Réat V, Parra J, Latgé G, Laval F, Demange P, Burlet-Schiltz O, Milon A, Daffé M, Tropis MG, Renault MAM.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4231-4236. doi: 10.1073/pnas.1617888114. Epub 2017 Apr 3.


Scrutiny of Mycobacterium tuberculosis 19 kDa antigen proteoforms provides new insights in the lipoglycoprotein biogenesis paradigm.

Parra J, Marcoux J, Poncin I, Canaan S, Herrmann JL, Nigou J, Burlet-Schiltz O, Rivière M.

Sci Rep. 2017 Mar 8;7:43682. doi: 10.1038/srep43682.


Rare Pedal Manifestation of Diffuse Multiple Myeloma Lesions.

Saviet BM, Marcoux JT, Narayanasami U.

J Foot Ankle Surg. 2017 Mar - Apr;56(2):357-361. doi: 10.1053/j.jfas.2016.11.020.


Antithrombotic agents intake prior to injury does not affect outcome after a traumatic brain injury in hospitalized elderly patients.

Julien J, Alsideiri G, Marcoux J, Hasen M, Correa JA, Feyz M, Maleki M, de Guise E.

J Clin Neurosci. 2017 Apr;38:122-125. doi: 10.1016/j.jocn.2016.12.032. Epub 2017 Jan 16.


Activation mode of the eukaryotic m2G10 tRNA methyltransferase Trm11 by its partner protein Trm112.

Bourgeois G, Marcoux J, Saliou JM, Cianférani S, Graille M.

Nucleic Acids Res. 2017 Feb 28;45(4):1971-1982. doi: 10.1093/nar/gkw1271.


Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.

Mehmood S, Marcoux J, Gault J, Quigley A, Michaelis S, Young SG, Carpenter EP, Robinson CV.

Nat Chem. 2016 Dec;8(12):1152-1158. doi: 10.1038/nchem.2591. Epub 2016 Aug 15.


Interdomain electron transfer in cellobiose dehydrogenase is governed by surface electrostatics.

Kadek A, Kavan D, Marcoux J, Stojko J, Felice AK, Cianférani S, Ludwig R, Halada P, Man P.

Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):157-167. doi: 10.1016/j.bbagen.2016.11.016. Epub 2016 Nov 13.


Traumatic brain injury in a rural indigenous population in Canada: a community-based approach to surveillance.

Lasry O, Dudley RW, Fuhrer R, Torrie J, Carlin R, Marcoux J.

CMAJ Open. 2016 May 25;4(2):E249-59. doi: 10.9778/cmajo.20150105. eCollection 2016 Apr-Jun.



Marcoux J, Saluja RS.

J Neurosurg. 2016 Feb;124(2):587. No abstract available.


Discharge Against Medical Advice in Traumatic Brain Injury: Follow-Up and Readmission Rate.

Marcoux J, Alkutbi M, Lamoureux J, Feyz M, Saluja RS, de Guise E.

Can J Neurol Sci. 2017 May;44(3):311-317. doi: 10.1017/cjn.2016.241. Epub 2016 May 26.


Rare Proximal Diaphyseal Stress Fractures of the Fifth Metatarsal Associated With Metatarsus Adductus.

Wamelink KE, Marcoux JT, Walrath SM.

J Foot Ankle Surg. 2016 Jul-Aug;55(4):788-93. doi: 10.1053/j.jfas.2016.03.005. Epub 2016 Apr 5.


Case report of tracheobronchial squamous cell carcinoma treated with radiation therapy and concurrent chemotherapy.

Agrawal V, Marcoux JP, Rabin MS, Vernovsky I, Wee JO, Mak RH.

Adv Radiat Oncol. 2016 Apr 1;1(2):127-131. doi: 10.1016/j.adro.2016.03.003. eCollection 2016 Apr-Jun. No abstract available.


Anti-PD-1 Inhibitor-Related Pneumonitis in Non-Small Cell Lung Cancer.

Nishino M, Chambers ES, Chong CR, Ramaiya NH, Gray SW, Marcoux JP, Hatabu H, Jänne PA, Hodi FS, Awad MM.

Cancer Immunol Res. 2016 Apr;4(4):289-93. doi: 10.1158/2326-6066.CIR-15-0267. Epub 2016 Feb 10.


Factor V Leiden and Cardiopulmonary Bypass.

Uppal V, Rosin M, Marcoux JA, Olson M, Bezaire J, Dalshaug G.

J Extra Corpor Technol. 2015 Dec;47(4):223-7.


Epidural Hematoma Treated Conservatively: When to Expect the Worst.

Basamh M, Robert A, Lamoureux J, Saluja RS, Marcoux J.

Can J Neurol Sci. 2016 Jan;43(1):74-81. doi: 10.1017/cjn.2015.232.


Temporal delays in trauma craniotomies.

Marcoux J, Bracco D, Saluja RS.

J Neurosurg. 2016 Sep;125(3):642-7. doi: 10.3171/2015.6.JNS15175. Epub 2016 Jan 1.


Olfactory function in acute traumatic brain injury.

Frasnelli J, Laguë-Beauvais M, LeBlanc J, Alturki AY, Champoux MC, Couturier C, Anderson K, Lamoureux J, Marcoux J, Tinawi S, Dagher J, Maleki M, Feyz M, de Guise E.

Clin Neurol Neurosurg. 2016 Jan;140:68-72. doi: 10.1016/j.clineuro.2015.11.013. Epub 2015 Nov 24.


Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.

Beck A, Terral G, Debaene F, Wagner-Rousset E, Marcoux J, Janin-Bussat MC, Colas O, Van Dorsselaer A, Cianférani S.

Expert Rev Proteomics. 2016;13(2):157-83. doi: 10.1586/14789450.2016.1132167. Epub 2016 Jan 22. Review.


Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C-ring assembly in T3SS.

McDowell MA, Marcoux J, McVicker G, Johnson S, Fong YH, Stevens R, Bowman LA, Degiacomi MT, Yan J, Wise A, Friede ME, Benesch JL, Deane JE, Tang CM, Robinson CV, Lea SM.

Mol Microbiol. 2016 Feb;99(4):749-66. doi: 10.1111/mmi.13267. Epub 2015 Dec 23.


A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.

Marcoux J, Mangione PP, Porcari R, Degiacomi MT, Verona G, Taylor GW, Giorgetti S, Raimondi S, Sanglier-Cianférani S, Benesch JL, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Stoppini M, Robinson CV, Pepys MB, Bellotti V.

EMBO Mol Med. 2015 Oct;7(10):1337-49. doi: 10.15252/emmm.201505357.


Towards integrative structural mass spectrometry: Benefits from hybrid approaches.

Marcoux J, Cianférani S.

Methods. 2015 Nov 1;89:4-12. doi: 10.1016/j.ymeth.2015.05.024. Epub 2015 May 29. Review.


Nonsurgical acute traumatic subdural hematoma: what is the risk?

Bajsarowicz P, Prakash I, Lamoureux J, Saluja RS, Feyz M, Maleki M, Marcoux J.

J Neurosurg. 2015 Nov;123(5):1176-83. doi: 10.3171/2014.10.JNS141728. Epub 2015 May 8.


Bivalirudin as an adjunctive anticoagulant to heparin in the treatment of heparin resistance during cardiopulmonary bypass-assisted cardiac surgery.

McNair E, Marcoux JA, Bally C, Gamble J, Thomson D.

Perfusion. 2016 Apr;31(3):189-99. doi: 10.1177/0267659115583525. Epub 2015 May 1. Review.


Differences in access to services in rural emergency departments of Quebec and Ontario.

Fleet R, Pelletier C, Marcoux J, Maltais-Giguère J, Archambault P, Audette LD, Plant J, Bégin F, Tounkara FK, Poitras J.

PLoS One. 2015 Apr 15;10(4):e0123746. doi: 10.1371/journal.pone.0123746. eCollection 2015.

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