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Items: 1 to 50 of 58

1.

Exosomal transfer of miR-126 promotes the anti-tumour response in malignant mesothelioma: Role of miR-126 in cancer-stroma communication.

Monaco F, Gaetani S, Alessandrini F, Tagliabracci A, Bracci M, Valentino M, Neuzil J, Amati M, Bovenzi M, Tomasetti M, Santarelli L.

Cancer Lett. 2019 Aug 7;463:27-36. doi: 10.1016/j.canlet.2019.08.001. [Epub ahead of print]

PMID:
31400405
2.

Effect of different anaesthetic techniques on gene expression profiles in patients who underwent hip arthroplasty.

Alleva R, Tognù A, Tomasetti M, Benassi MS, Pazzaglia L, van Oven H, Viganò E, De Simone N, Pacini I, Giannone S, Gagic S, Borghi R, Picone S, Borghi B.

PLoS One. 2019 Jul 25;14(7):e0219113. doi: 10.1371/journal.pone.0219113. eCollection 2019.

3.

Four-miRNA Signature to Identify Asbestos-Related Lung Malignancies.

Santarelli L, Gaetani S, Monaco F, Bracci M, Valentino M, Amati M, Rubini C, Sabbatini A, Pasquini E, Zanotta N, Comar M, Neuzil J, Tomasetti M, Bovenzi M.

Cancer Epidemiol Biomarkers Prev. 2019 Jan;28(1):119-126. doi: 10.1158/1055-9965.EPI-18-0453. Epub 2018 Sep 26.

PMID:
30257964
4.

MiR-126 in intestinal-type sinonasal adenocarcinomas: exosomal transfer of MiR-126 promotes anti-tumour responses.

Tomasetti M, Re M, Monaco F, Gaetani S, Rubini C, Bertini A, Pasquini E, Bersaglieri C, Bracci M, Staffolani S, Colomba M, Gregorini A, Valentino M, Tagliabracci A, Bovenzi M, Neuzil J, Amati M, Santarelli L.

BMC Cancer. 2018 Sep 17;18(1):896. doi: 10.1186/s12885-018-4801-z.

5.

DNA damage response in workers exposed to low-dose ionising radiation.

Gaetani S, Monaco F, Bracci M, Ciarapica V, Impollonia G, Valentino M, Tomasetti M, Santarelli L, Amati M.

Occup Environ Med. 2018 Oct;75(10):724-729. doi: 10.1136/oemed-2018-105094. Epub 2018 Aug 7.

PMID:
30087158
6.

Mechanism underlying the effect of long-term exposure to low dose of pesticides on DNA integrity.

Alleva R, Manzella N, Gaetani S, Bacchetti T, Bracci M, Ciarapica V, Monaco F, Borghi B, Amati M, Ferretti G, Tomasetti M.

Environ Toxicol. 2018 Apr;33(4):476-487. doi: 10.1002/tox.22534. Epub 2018 Jan 23. Erratum in: Environ Toxicol. 2018 Dec;33(12):1329.

PMID:
29359425
7.

Exosomal miR-126 as a circulating biomarker in non-small-cell lung cancer regulating cancer progression.

Grimolizzi F, Monaco F, Leoni F, Bracci M, Staffolani S, Bersaglieri C, Gaetani S, Valentino M, Amati M, Rubini C, Saccucci F, Neuzil J, Tomasetti M, Santarelli L.

Sci Rep. 2017 Nov 10;7(1):15277. doi: 10.1038/s41598-017-15475-6.

8.

Exosome-derived microRNAs in cancer metabolism: possible implications in cancer diagnostics and therapy.

Tomasetti M, Lee W, Santarelli L, Neuzil J.

Exp Mol Med. 2017 Jan 20;49(1):e285. doi: 10.1038/emm.2016.153. Review.

9.

Circulating epigenetic biomarkers in lung malignancies: From early diagnosis to therapy.

Tomasetti M, Amati M, Neuzil J, Santarelli L.

Lung Cancer. 2017 May;107:65-72. doi: 10.1016/j.lungcan.2016.05.023. Epub 2016 Jun 2. Review.

PMID:
27312601
10.

MicroRNA in Metabolic Re-Programming and Their Role in Tumorigenesis.

Tomasetti M, Amati M, Santarelli L, Neuzil J.

Int J Mol Sci. 2016 May 18;17(5). pii: E754. doi: 10.3390/ijms17050754. Review.

11.

Correction: Characterisation of Mesothelioma-Initiating Cells and Their Susceptibility to Anti-Cancer Agents.

Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J.

PLoS One. 2016 May 17;11(5):e0156012. doi: 10.1371/journal.pone.0156012. eCollection 2016.

12.

Organic honey supplementation reverses pesticide-induced genotoxicity by modulating DNA damage response.

Alleva R, Manzella N, Gaetani S, Ciarapica V, Bracci M, Caboni MF, Pasini F, Monaco F, Amati M, Borghi B, Tomasetti M.

Mol Nutr Food Res. 2016 Oct;60(10):2243-2255. doi: 10.1002/mnfr.201600005. Epub 2016 May 30.

PMID:
27129605
13.

Peripheral Skin Temperature and Circadian Biological Clock in Shift Nurses after a Day off.

Bracci M, Ciarapica V, Copertaro A, Barbaresi M, Manzella N, Tomasetti M, Gaetani S, Monaco F, Amati M, Valentino M, Rapisarda V, Santarelli L.

Int J Mol Sci. 2016 Apr 26;17(5). pii: E623. doi: 10.3390/ijms17050623.

14.

MicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma.

Tomasetti M, Monaco F, Manzella N, Rohlena J, Rohlenova K, Staffolani S, Gaetani S, Ciarapica V, Amati M, Bracci M, Valentino M, Goodwin J, Nguyen M, Truksa J, Sobol M, Hozak P, Dong LF, Santarelli L, Neuzil J.

Oncotarget. 2016 Jun 14;7(24):36338-36352. doi: 10.18632/oncotarget.8916.

15.

Combined circulating epigenetic markers to improve mesothelin performance in the diagnosis of malignant mesothelioma.

Santarelli L, Staffolani S, Strafella E, Nocchi L, Manzella N, Grossi P, Bracci M, Pignotti E, Alleva R, Borghi B, Pompili C, Sabbatini A, Rubini C, Zuccatosta L, Bichisecchi E, Valentino M, Horwood K, Comar M, Bovenzi M, Dong LF, Neuzil J, Amati M, Tomasetti M.

Lung Cancer. 2015 Dec;90(3):457-64. doi: 10.1016/j.lungcan.2015.09.021. Epub 2015 Sep 25.

PMID:
26431916
16.

Sub-apoptotic dosages of pro-oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysis.

Tremante E, Santarelli L, Lo Monaco E, Sampaoli C, Ingegnere T, Guerrieri R, Tomasetti M, Giacomini P.

Oncotarget. 2015 Oct 13;6(31):31039-49. doi: 10.18632/oncotarget.5024.

17.

Circadian Modulation of 8-Oxoguanine DNA Damage Repair.

Manzella N, Bracci M, Strafella E, Staffolani S, Ciarapica V, Copertaro A, Rapisarda V, Ledda C, Amati M, Valentino M, Tomasetti M, Stevens RG, Santarelli L.

Sci Rep. 2015 Sep 4;5:13752. doi: 10.1038/srep13752.

18.

Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents.

Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J.

PLoS One. 2015 May 1;10(5):e0119549. doi: 10.1371/journal.pone.0119549. eCollection 2015. Erratum in: PLoS One. 2016;11(5):e0156012.

19.

Wood dust exposure induces cell transformation through EGFR-mediated OGG1 inhibition.

Staffolani S, Manzella N, Strafella E, Nocchi L, Bracci M, Ciarapica V, Amati M, Rubini C, Re M, Pugnaloni A, Pasquini E, Tarchini P, Valentino M, Tomasetti M, Santarelli L.

Mutagenesis. 2015 Jul;30(4):487-97. doi: 10.1093/mutage/gev007. Epub 2015 Feb 23.

PMID:
25711499
20.

Raw and thermally treated cement asbestos exerts different cytotoxicity effects on A549 cells in vitro.

Pugnaloni A, Lucarini G, Rubini C, Smorlesi A, Tomasetti M, Strafella E, Armeni T, Gualtieri AF.

Acta Histochem. 2015 Jan;117(1):29-39. doi: 10.1016/j.acthis.2014.10.007. Epub 2014 Nov 22.

PMID:
25466987
21.

Role of nicotinamide N-methyltransferase in non-small cell lung cancer: in vitro effect of shRNA-mediated gene silencing on tumourigenicity.

Sartini D, Seta R, Pozzi V, Morganti S, Rubini C, Zizzi A, Tomasetti M, Santarelli L, Emanuelli M.

Biol Chem. 2015 Mar;396(3):225-34. doi: 10.1515/hsz-2014-0231.

PMID:
25204218
22.

MicroRNA regulation of cancer metabolism: role in tumour suppression.

Tomasetti M, Santarelli L, Neuzil J, Dong L.

Mitochondrion. 2014 Nov;19 Pt A:29-38. doi: 10.1016/j.mito.2014.06.004. Epub 2014 Jun 21.

PMID:
24960472
23.

MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial function.

Tomasetti M, Nocchi L, Staffolani S, Manzella N, Amati M, Goodwin J, Kluckova K, Nguyen M, Strafella E, Bajzikova M, Peterka M, Lettlova S, Truksa J, Lee W, Dong LF, Santarelli L, Neuzil J.

Antioxid Redox Signal. 2014 Nov 20;21(15):2109-25. doi: 10.1089/ars.2013.5215. Epub 2014 Apr 23.

24.

Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy.

Kovarova J, Bajzikova M, Vondrusova M, Stursa J, Goodwin J, Nguyen M, Zobalova R, Pesdar EA, Truksa J, Tomasetti M, Dong LF, Neuzil J.

Redox Rep. 2014 Jan;19(1):16-25. doi: 10.1179/1351000213Y.0000000064. Epub 2013 Nov 12.

PMID:
24225203
25.

Occupational styrene exposure induces stress-responsive genes involved in cytoprotective and cytotoxic activities.

Strafella E, Bracci M, Staffolani S, Manzella N, Giantomasi D, Valentino M, Amati M, Tomasetti M, Santarelli L.

PLoS One. 2013 Sep 23;8(9):e75401. doi: 10.1371/journal.pone.0075401. eCollection 2013.

26.

MicroRNAs as regulators of mitochondrial function: role in cancer suppression.

Tomasetti M, Neuzil J, Dong L.

Biochim Biophys Acta. 2014 Apr;1840(4):1441-53. doi: 10.1016/j.bbagen.2013.09.002. Epub 2013 Sep 7. Review.

PMID:
24016605
27.

RNA-mediated gene silencing of nicotinamide N-methyltransferase is associated with decreased tumorigenicity in human oral carcinoma cells.

Pozzi V, Sartini D, Morganti S, Giuliante R, Di Ruscio G, Santarelli A, Rocchetti R, Rubini C, Tomasetti M, Giannatempo G, Orlando F, Provinciali M, Lo Muzio L, Emanuelli M.

PLoS One. 2013 Aug 21;8(8):e71272. doi: 10.1371/journal.pone.0071272. eCollection 2013.

28.

Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death.

Tomasetti M, Nocchi L, Neuzil J, Goodwin J, Nguyen M, Dong L, Manzella N, Staffolani S, Milanese C, Garrone B, Alleva R, Borghi B, Santarelli L, Guerrieri R.

PLoS One. 2012;7(12):e52263. doi: 10.1371/journal.pone.0052263. Epub 2012 Dec 18.

29.

Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis.

Hollevoet K, Reitsma JB, Creaney J, Grigoriu BD, Robinson BW, Scherpereel A, Cristaudo A, Pass HI, Nackaerts K, Rodríguez Portal JA, Schneider J, Muley T, Di Serio F, Baas P, Tomasetti M, Rai AJ, van Meerbeeck JP.

J Clin Oncol. 2012 May 1;30(13):1541-9. doi: 10.1200/JCO.2011.39.6671. Epub 2012 Mar 12. Review.

30.

Clinical significance of circulating miR-126 quantification in malignant mesothelioma patients.

Tomasetti M, Staffolani S, Nocchi L, Neuzil J, Strafella E, Manzella N, Mariotti L, Bracci M, Valentino M, Amati M, Santarelli L.

Clin Biochem. 2012 May;45(7-8):575-81. doi: 10.1016/j.clinbiochem.2012.02.009. Epub 2012 Feb 21.

PMID:
22374169
31.

Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.

Alleva R, Di Donato F, Strafella E, Staffolani S, Nocchi L, Borghi B, Pignotti E, Santarelli L, Tomasetti M.

Br J Nutr. 2012 Jun;107(11):1645-54. doi: 10.1017/S0007114511004806. Epub 2011 Sep 16.

PMID:
21920059
32.

Angiogenic effect induced by mineral fibres.

Carbonari D, Campopiano A, Ramires D, Strafella E, Staffolani S, Tomasetti M, Curini R, Valentino M, Santarelli L, Amati M.

Toxicology. 2011 Oct 9;288(1-3):34-42. doi: 10.1016/j.tox.2011.06.016. Epub 2011 Jul 5.

PMID:
21762757
33.

Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis.

Tomasetti M, Amati M, Nocchi L, Saccucci F, Strafella E, Staffolani S, Tarquini LM, Carbonari D, Alleva R, Borghi B, Neuzil J, Bracci M, Santarelli L.

Mutagenesis. 2011 Sep;26(5):585-91. doi: 10.1093/mutage/ger020. Epub 2011 May 4.

PMID:
21543585
34.

Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism.

Nocchi L, Tomasetti M, Amati M, Neuzil J, Santarelli L, Saccucci F.

J Biol Chem. 2011 Jun 3;286(22):19478-88. doi: 10.1074/jbc.M110.217331. Epub 2011 Apr 12.

35.

Association of MiR-126 with soluble mesothelin-related peptides, a marker for malignant mesothelioma.

Santarelli L, Strafella E, Staffolani S, Amati M, Emanuelli M, Sartini D, Pozzi V, Carbonari D, Bracci M, Pignotti E, Mazzanti P, Sabbatini A, Ranaldi R, Gasparini S, Neuzil J, Tomasetti M.

PLoS One. 2011 Apr 1;6(4):e18232. doi: 10.1371/journal.pone.0018232.

36.

In vitro effect of aspartame in angiogenesis induction.

Alleva R, Borghi B, Santarelli L, Strafella E, Carbonari D, Bracci M, Tomasetti M.

Toxicol In Vitro. 2011 Feb;25(1):286-93. doi: 10.1016/j.tiv.2010.09.002. Epub 2010 Sep 17.

PMID:
20837131
37.

Biological effects and comparative cytotoxicity of thermal transformed asbestos-containing materials in a human alveolar epithelial cell line.

Giantomassi F, Gualtieri AF, Santarelli L, Tomasetti M, Lusvardi G, Lucarini G, Governa M, Pugnaloni A.

Toxicol In Vitro. 2010 Sep;24(6):1521-31. doi: 10.1016/j.tiv.2010.07.009. Epub 2010 Jul 15.

PMID:
20637854
38.

Biomarkers for early detection of malignant mesothelioma: diagnostic and therapeutic application.

Tomasetti M, Santarelli L.

Cancers (Basel). 2010 Apr 14;2(2):523-48. doi: 10.3390/cancers2020523.

39.

Relationship of job satisfaction, psychological distress and stress-related biological parameters among healthy nurses: a longitudinal study.

Amati M, Tomasetti M, Ciuccarelli M, Mariotti L, Tarquini LM, Bracci M, Baldassari M, Balducci C, Alleva R, Borghi B, Mocchegiani E, Copertaro A, Santarelli L.

J Occup Health. 2010;52(1):31-8. Epub 2009 Dec 22.

40.

Malignant mesothelioma: biology, diagnosis and therapeutic approaches.

Tomasetti M, Amati M, Santarelli L, Alleva R, Neuzil J.

Curr Mol Pharmacol. 2009 Jun;2(2):190-206. Review.

PMID:
20021458
41.

L-arginine reduces mercury accumulation in thymus of mercury-exposed mice: role of nitric oxide synthase activity and metallothioneins.

Bracci M, Tomasetti M, Malavolta M, Bonacucina V, Mocchegiani E, Santarelli L.

Ind Health. 2008 Dec;46(6):567-74.

42.

Assessment of biomarkers in asbestos-exposed workers as indicators of cancer risk.

Amati M, Tomasetti M, Mariotti L, Tarquini LM, Valentino M, Santarelli L.

Mutat Res. 2008 Aug-Sep;655(1-2):52-8. doi: 10.1016/j.mrgentox.2008.06.011.

PMID:
18638565
43.

Profiling tumor-associated markers for early detection of malignant mesothelioma: an epidemiologic study.

Amati M, Tomasetti M, Scartozzi M, Mariotti L, Alleva R, Pignotti E, Borghi B, Valentino M, Governa M, Neuzil J, Santarelli L.

Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):163-70. doi: 10.1158/1055-9965.EPI-07-0607.

44.

alpha-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapy.

Alleva R, Tomasetti M, Sartini D, Emanuelli M, Nasole E, Di Donato F, Borghi B, Santarelli L, Neuzil J.

Mol Med. 2008 Mar-Apr;14(3-4):175-83.

45.

Vitamin E analogues and immune response in cancer treatment.

Tomasetti M, Neuzil J.

Vitam Horm. 2007;76:463-91. Review.

PMID:
17628186
46.

Vitamin E analogs, a novel group of "mitocans," as anticancer agents: the importance of being redox-silent.

Neuzil J, Tomasetti M, Zhao Y, Dong LF, Birringer M, Wang XF, Low P, Wu K, Salvatore BA, Ralph SJ.

Mol Pharmacol. 2007 May;71(5):1185-99. Epub 2007 Jan 12. Review.

PMID:
17220355
47.

CD38 expression enhances sensitivity of lymphoma T and B cell lines to biochemical and receptor-mediated apoptosis.

Gregorini A, Tomasetti M, Cinti C, Colomba D, Colomba S.

Cell Biol Int. 2006 Sep;30(9):727-32. Epub 2006 May 16.

PMID:
16839787
48.

Vitamin E analogues as anticancer agents: lessons from studies with alpha-tocopheryl succinate.

Wang XF, Dong L, Zhao Y, Tomasetti M, Wu K, Neuzil J.

Mol Nutr Food Res. 2006 Aug;50(8):675-85. Review.

PMID:
16835868
49.

Alpha-tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: implication for sensitisation of resistant cancer cells to TRAIL apoptosis.

Tomasetti M, Andera L, Alleva R, Borghi B, Neuzil J, Procopio A.

FEBS Lett. 2006 Apr 3;580(8):1925-31. Epub 2006 Feb 28.

50.

Alpha-tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis.

Alleva R, Benassi MS, Pazzaglia L, Tomasetti M, Gellert N, Borghi B, Neuzil J, Picci P.

Cancer Lett. 2006 Feb 8;232(2):226-35.

PMID:
16458119

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