Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 71

1.

Prediction of response to drug therapy in psychiatric disorders.

Stern S, Linker S, Vadodaria KC, Marchetto MC, Gage FH.

Open Biol. 2018 May;8(5). pii: 180031. doi: 10.1098/rsob.180031. Review.

2.

Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro.

Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH.

Cell Stem Cell. 2018 May 3;22(5):684-697.e9. doi: 10.1016/j.stem.2018.04.009.

PMID:
29727680
3.

Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein.

Vőfély G, Berecz T, Szabó E, Szebényi K, Hathy E, Orbán TI, Sarkadi B, Homolya L, Marchetto MC, Réthelyi JM, Apáti Á.

Mol Cell Neurosci. 2018 Apr;88:222-230. doi: 10.1016/j.mcn.2018.02.003. Epub 2018 Feb 6.

PMID:
29425968
4.

Modeling psychiatric disorders using patient stem cell-derived neurons: a way forward.

Vadodaria KC, Amatya DN, Marchetto MC, Gage FH.

Genome Med. 2018 Jan 4;10(1):1. doi: 10.1186/s13073-017-0512-3.

5.

Serotonin in psychiatry: in vitro disease modeling using patient-derived neurons.

Vadodaria KC, Stern S, Marchetto MC, Gage FH.

Cell Tissue Res. 2018 Jan;371(1):161-170. doi: 10.1007/s00441-017-2670-4. Epub 2017 Aug 15. Review.

PMID:
28812143
6.

Examining non-LTR retrotransposons in the context of the evolving primate brain.

Linker SB, Marchetto MC, Narvaiza I, Denli AM, Gage FH.

BMC Biol. 2017 Aug 11;15(1):68. doi: 10.1186/s12915-017-0409-z. Review.

7.

Intact piRNA pathway prevents L1 mobilization in male meiosis.

Newkirk SJ, Lee S, Grandi FC, Gaysinskaya V, Rosser JM, Vanden Berg N, Hogarth CA, Marchetto MCN, Muotri AR, Griswold MD, Ye P, Bortvin A, Gage FH, Boeke JD, An W.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5635-E5644. doi: 10.1073/pnas.1701069114. Epub 2017 Jun 19.

8.

Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells.

Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, Ku M, Denli AM, Kerman BE, Charnay P, Kelsoe JR, Marchetto MC, Gage FH.

Stem Cell Reports. 2017 Jun 6;8(6):1757-1769. doi: 10.1016/j.stemcr.2017.05.011.

9.

Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin.

Franks TM, Benner C, Narvaiza I, Marchetto MCN, Young JM, Malik HS, Gage FH, Hetzer MW.

Genes Dev. 2017 Apr 15;31(8):845. doi: 10.1101/gad.300699.117. No abstract available.

10.

Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges.

Kim Y, Santos R, Gage FH, Marchetto MC.

Front Cell Neurosci. 2017 Feb 14;11:30. doi: 10.3389/fncel.2017.00030. eCollection 2017. Review.

11.

Conserved expression of transposon-derived non-coding transcripts in primate stem cells.

Ramsay L, Marchetto MC, Caron M, Chen SH, Busche S, Kwan T, Pastinen T, Gage FH, Bourque G.

BMC Genomics. 2017 Feb 28;18(1):214. doi: 10.1186/s12864-017-3568-y.

12.

Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium.

Stern S, Santos R, Marchetto MC, Mendes APD, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH.

Mol Psychiatry. 2018 Jun;23(6):1453-1465. doi: 10.1038/mp.2016.260. Epub 2017 Feb 28.

13.

Generating human serotonergic neurons in vitro: Methodological advances.

Vadodaria KC, Marchetto MC, Mertens J, Gage FH.

Bioessays. 2016 Nov;38(11):1123-1129. doi: 10.1002/bies.201600127. Epub 2016 Sep 22. Review.

PMID:
27716980
14.

A human neurodevelopmental model for Williams syndrome.

Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR.

Nature. 2016 Aug 18;536(7616):338-43. Epub 2016 Aug 10.

15.

Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility.

Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, Denman L, Harshman L, Baker C, Raja A, Penewit K, Janke N, Tang WJ, Ventura M, Banci L, Antonacci F, Akey JM, Amemiya CT, Gage FH, Reymond A, Eichler EE.

Nature. 2016 Aug 11;536(7615):205-9. Epub 2016 Aug 3.

16.

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals.

Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria K, Beltrao-Braga P, Trujillo CA, Mendes APD, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand K, Pierce K, Eichenfield L, Pramparo T, Eyler L, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR.

Mol Psychiatry. 2017 Jun;22(6):820-835. doi: 10.1038/mp.2016.95. Epub 2016 Jul 5.

17.

Evolution of a transcriptional regulator from a transmembrane nucleoporin.

Franks TM, Benner C, Narvaiza I, Marchetto MC, Young JM, Malik HS, Gage FH, Hetzer MW.

Genes Dev. 2016 May 15;30(10):1155-71. doi: 10.1101/gad.280941.116. Epub 2016 May 19. Erratum in: Genes Dev. 2017 Apr 15;31(8):845.

18.

Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience.

Mertens J, Marchetto MC, Bardy C, Gage FH.

Nat Rev Neurosci. 2016 Jul;17(7):424-37. doi: 10.1038/nrn.2016.46. Epub 2016 May 19. Review.

PMID:
27194476
19.

2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size.

Otani T, Marchetto MC, Gage FH, Simons BD, Livesey FJ.

Cell Stem Cell. 2016 Apr 7;18(4):467-80. doi: 10.1016/j.stem.2016.03.003. Epub 2016 Mar 31.

20.

KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome.

Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):751-6. doi: 10.1073/pnas.1524013113. Epub 2016 Jan 5.

21.

Synaptic activity: An emerging player in schizophrenia.

Sarkar A, Marchetto MC, Gage FH.

Brain Res. 2017 Feb 1;1656:68-75. doi: 10.1016/j.brainres.2015.12.028. Epub 2015 Dec 23. Review.

PMID:
26723567
22.

The different moods of human serotonergic neurons.

Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH.

Mol Psychiatry. 2016 Jan;21(1):3. doi: 10.1038/mp.2015.202. No abstract available.

PMID:
26678308
23.

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.

Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R.

Stem Cell Reports. 2015 Dec 8;5(6):933-945. doi: 10.1016/j.stemcr.2015.10.011. Epub 2015 Nov 21.

24.

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.

Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Oedegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM; Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J.

Nature. 2016 Feb 11;530(7589):242. doi: 10.1038/nature16182. Epub 2015 Nov 25. No abstract available.

PMID:
26605530
25.

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.

Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM; Pharmacogenomics of Bipolar Disorder Study, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J.

Nature. 2015 Nov 5;527(7576):95-9. doi: 10.1038/nature15526. Epub 2015 Oct 28. Erratum in: Nature. 2016 Feb 11;530(7589):242. Alba, Martin [Corrected to Alda, Martin].

26.

Generation of functional human serotonergic neurons from fibroblasts.

Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH.

Mol Psychiatry. 2016 Jan;21(1):49-61. doi: 10.1038/mp.2015.161. Epub 2015 Oct 27.

PMID:
26503761
27.

Primate-specific ORF0 contributes to retrotransposon-mediated diversity.

Denli AM, Narvaiza I, Kerman BE, Pena M, Benner C, Marchetto MC, Diedrich JK, Aslanian A, Ma J, Moresco JJ, Moore L, Hunter T, Saghatelian A, Gage FH.

Cell. 2015 Oct 22;163(3):583-93. doi: 10.1016/j.cell.2015.09.025. Epub 2015 Oct 22.

28.

Enhancer divergence and cis-regulatory evolution in the human and chimp neural crest.

Prescott SL, Srinivasan R, Marchetto MC, Grishina I, Narvaiza I, Selleri L, Gage FH, Swigut T, Wysocka J.

Cell. 2015 Sep 24;163(1):68-83. doi: 10.1016/j.cell.2015.08.036. Epub 2015 Sep 10.

29.

Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons.

Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR.

Mol Psychiatry. 2015 Nov;20(11):1350-65. doi: 10.1038/mp.2014.141. Epub 2014 Nov 11.

30.

Your brain under the microscope: the promise of stem cells.

Marchetto MC, Gage FH.

Cerebrum. 2014 Jan 1;2014:1. eCollection 2014 Jan.

31.

Mobile DNA elements in the generation of diversity and complexity in the brain.

Erwin JA, Marchetto MC, Gage FH.

Nat Rev Neurosci. 2014 Aug;15(8):497-506. doi: 10.1038/nrn3730. Epub 2014 Jul 9. Review.

32.

A quantitative framework to evaluate modeling of cortical development by neural stem cells.

Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH.

Neuron. 2014 Jul 2;83(1):69-86. doi: 10.1016/j.neuron.2014.05.035.

33.

How to make a hippocampal dentate gyrus granule neuron.

Yu DX, Marchetto MC, Gage FH.

Development. 2014 Jun;141(12):2366-75. doi: 10.1242/dev.096776. Review.

34.

Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease.

Winner B, Marchetto MC, Winkler J, Gage FH.

Hum Mol Genet. 2014 Sep 15;23(R1):R27-34. doi: 10.1093/hmg/ddu205. Epub 2014 May 12. Review.

PMID:
24821704
35.

Modeling hippocampal neurogenesis using human pluripotent stem cells.

Yu DX, Di Giorgio FP, Yao J, Marchetto MC, Brennand K, Wright R, Mei A, McHenry L, Lisuk D, Grasmick JM, Silberman P, Silberman G, Jappelli R, Gage FH.

Stem Cell Reports. 2014 Feb 27;2(3):295-310. doi: 10.1016/j.stemcr.2014.01.009. eCollection 2014 Mar 11. Erratum in: Stem Cell Reports. 2014 Jul 8;3(1):217.

36.

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons.

Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, Schlötzer-Schrehardt U, Winkler J, Gage FH, Winner B.

Hum Mol Genet. 2014 May 15;23(10):2527-41. doi: 10.1093/hmg/ddt644. Epub 2013 Dec 30.

37.

Differential L1 regulation in pluripotent stem cells of humans and apes.

Marchetto MCN, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola ACM, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH.

Nature. 2013 Nov 28;503(7477):525-529. doi: 10.1038/nature12686. Epub 2013 Oct 23.

38.

Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells.

Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR.

Biol Psychiatry. 2014 Jun 15;75(12):929-35. doi: 10.1016/j.biopsych.2013.08.007. Epub 2013 Sep 14. Review.

PMID:
24041506
39.

Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells.

Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G.

Stem Cell Res. 2013 Sep;11(2):743-57. doi: 10.1016/j.scr.2013.05.002. Epub 2013 May 16.

40.

Therapeutic translation of iPSCs for treating neurological disease.

Yu DX, Marchetto MC, Gage FH.

Cell Stem Cell. 2013 Jun 6;12(6):678-88. doi: 10.1016/j.stem.2013.05.018.

41.

Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2013 Jun 5;5(188):188lr2. doi: 10.1126/scitranslmed.3005697.

42.

Dynamic association of NUP98 with the human genome.

Liang Y, Franks TM, Marchetto MC, Gage FH, Hetzer MW.

PLoS Genet. 2013;9(2):e1003308. doi: 10.1371/journal.pgen.1003308. Epub 2013 Feb 28.

43.

Induced pluripotent stem cells: the new patient?

Bellin M, Marchetto MC, Gage FH, Mummery CL.

Nat Rev Mol Cell Biol. 2012 Nov;13(11):713-26. doi: 10.1038/nrm3448. Epub 2012 Oct 4. Review.

PMID:
23034453
44.

The role of DNA repair in the pluripotency and differentiation of human stem cells.

Rocha CR, Lerner LK, Okamoto OK, Marchetto MC, Menck CF.

Mutat Res. 2013 Jan-Mar;752(1):25-35. doi: 10.1016/j.mrrev.2012.09.001. Epub 2012 Sep 23. Review.

PMID:
23010441
45.

Drug screening for ALS using patient-specific induced pluripotent stem cells.

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2012 Aug 1;4(145):145ra104. doi: 10.1126/scitranslmed.3004052.

46.

Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc.

Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH, Izpisua Belmonte JC.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12556-61. doi: 10.1073/pnas.1209523109. Epub 2012 Jul 18.

47.

Modeling brain disease in a dish: really?

Marchetto MC, Gage FH.

Cell Stem Cell. 2012 Jun 14;10(6):642-5. doi: 10.1016/j.stem.2012.05.008.

48.

Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells.

Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20382-7. doi: 10.1073/pnas.1100273108. Epub 2011 Dec 9.

49.

Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises.

Marchetto MC, Brennand KJ, Boyer LF, Gage FH.

Hum Mol Genet. 2011 Oct 15;20(R2):R109-15. doi: 10.1093/hmg/ddr336. Epub 2011 Aug 9. Review.

50.

Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients.

Mitne-Neto M, Machado-Costa M, Marchetto MC, Bengtson MH, Joazeiro CA, Tsuda H, Bellen HJ, Silva HC, Oliveira AS, Lazar M, Muotri AR, Zatz M.

Hum Mol Genet. 2011 Sep 15;20(18):3642-52. doi: 10.1093/hmg/ddr284. Epub 2011 Jun 17.

Supplemental Content

Loading ...
Support Center