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Items: 1 to 50 of 96


Changing the academic culture: valuing patents and commercialization toward tenure and career advancement.

Sanberg PR, Gharib M, Harker PT, Kaler EW, Marchase RB, Sands TD, Arshadi N, Sarkar S.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6542-7. doi: 10.1073/pnas.1404094111. Epub 2014 Apr 28.


Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function.

Collins HE, He L, Zou L, Qu J, Zhou L, Litovsky SH, Yang Q, Young ME, Marchase RB, Chatham JC.

Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1231-9. doi: 10.1152/ajpheart.00075.2014. Epub 2014 Feb 28.


O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses.

Taylor EW, Wang K, Nelson AR, Bredemann TM, Fraser KB, Clinton SM, Puckett R, Marchase RB, Chatham JC, McMahon LL.

J Neurosci. 2014 Jan 1;34(1):10-21. doi: 10.1523/JNEUROSCI.4761-12.2014.


STIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathology.

Collins HE, Zhu-Mauldin X, Marchase RB, Chatham JC.

Am J Physiol Heart Circ Physiol. 2013 Aug 15;305(4):H446-58. doi: 10.1152/ajpheart.00104.2013. Epub 2013 Jun 21. Review.


Modification of STIM1 by O-linked N-acetylglucosamine (O-GlcNAc) attenuates store-operated calcium entry in neonatal cardiomyocytes.

Zhu-Mauldin X, Marsh SA, Zou L, Marchase RB, Chatham JC.

J Biol Chem. 2012 Nov 9;287(46):39094-106. doi: 10.1074/jbc.M112.383778. Epub 2012 Sep 19.


Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependent.

Zou L, Zhu-Mauldin X, Marchase RB, Paterson AJ, Liu J, Yang Q, Chatham JC.

J Biol Chem. 2012 Oct 5;287(41):34419-31. doi: 10.1074/jbc.M112.393207. Epub 2012 Aug 20.


Protein O-GlcNAcylation: A critical regulator of the cellular response to stress.

Chatham JC, Marchase RB.

Curr Signal Transduct Ther. 2010 Jan;5(1):49-59.


Increased O-linked beta-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats.

Nöt LG, Brocks CA, Vámhidy L, Marchase RB, Chatham JC.

Crit Care Med. 2010 Feb;38(2):562-71. doi: 10.1097/CCM.0b013e3181cb10b3.


The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses.

Chatham JC, Marchase RB.

Biochim Biophys Acta. 2010 Feb;1800(2):57-66. doi: 10.1016/j.bbagen.2009.07.004. Epub 2009 Jul 14. Review.


Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling.

Zou L, Yang S, Champattanachai V, Hu S, Chaudry IH, Marchase RB, Chatham JC.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H515-23. doi: 10.1152/ajpheart.01025.2008. Epub 2008 Dec 19.


Retraction: Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients.

Marchase RB.

Transplantation. 2008 Aug 15;86(3):482. doi: 10.1097/TP0b013e318186833F. No abstract available.


Retraction: Peritransplant tolerance induction in macaques: early events reflecting the unique synergy between immunotoxin and deoxyspergualin.

Marchase RB.

Transplantation. 2008 Aug 15;86(3):482. doi: 10.1097/ No abstract available.


Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2.

Champattanachai V, Marchase RB, Chatham JC.

Am J Physiol Cell Physiol. 2008 Jun;294(6):C1509-20. doi: 10.1152/ajpcell.00456.2007. Epub 2008 Mar 26.


Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats.

Fülöp N, Feng W, Xing D, He K, Nőt LG, Brocks CA, Marchase RB, Miller AP, Chatham JC.

Biogerontology. 2008 Jun;9(3):139. doi: 10.1007/s10522-007-9123-5. Epub 2008 Jan 10.


Overexpression of TRPC3 increases apoptosis but not necrosis in response to ischemia-reperfusion in adult mouse cardiomyocytes.

Shan D, Marchase RB, Chatham JC.

Am J Physiol Cell Physiol. 2008 Mar;294(3):C833-41. doi: 10.1152/ajpcell.00313.2007. Epub 2008 Jan 9.


Hexosamine biosynthesis and protein O-glycosylation: the first line of defense against stress, ischemia, and trauma.

Chatham JC, Nöt LG, Fülöp N, Marchase RB.

Shock. 2008 Apr;29(4):431-40. Review.


Increased O-GlcNAc levels during reperfusion lead to improved functional recovery and reduced calpain proteolysis.

Liu J, Marchase RB, Chatham JC.

Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1391-9. Epub 2007 Jun 15.


Glucosamine administration improves survival rate after severe hemorrhagic shock combined with trauma in rats.

Nöt LG, Marchase RB, Fülöp N, Brocks CA, Chatham JC.

Shock. 2007 Sep;28(3):345-52.


The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels.

Zou L, Yang S, Hu S, Chaudry IH, Marchase RB, Chatham JC.

Shock. 2007 Apr;27(4):402-8.


Glucosamine cardioprotection in perfused rat hearts associated with increased O-linked N-acetylglucosamine protein modification and altered p38 activation.

Fülöp N, Zhang Z, Marchase RB, Chatham JC.

Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2227-36. Epub 2007 Jan 5.


Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart.

Fülöp N, Mason MM, Dutta K, Wang P, Davidoff AJ, Marchase RB, Chatham JC.

Am J Physiol Cell Physiol. 2007 Apr;292(4):C1370-8. Epub 2006 Nov 29.


Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system.

Fülöp N, Marchase RB, Chatham JC.

Cardiovasc Res. 2007 Jan 15;73(2):288-97. Epub 2006 Jul 29. Review.


Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc.

Champattanachai V, Marchase RB, Chatham JC.

Am J Physiol Cell Physiol. 2007 Jan;292(1):C178-87. Epub 2006 Aug 9.


Glucosamine administration during resuscitation improves organ function after trauma hemorrhage.

Yang S, Zou LY, Bounelis P, Chaudry I, Chatham JC, Marchase RB.

Shock. 2006 Jun;25(6):600-7.


Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia.

Liu J, Pang Y, Chang T, Bounelis P, Chatham JC, Marchase RB.

J Mol Cell Cardiol. 2006 Feb;40(2):303-12. Epub 2005 Dec 9.


Glucosamine inhibits angiotensin II-induced cytoplasmic Ca2+ elevation in neonatal cardiomyocytes via protein-associated O-linked N-acetylglucosamine.

Nagy T, Champattanachai V, Marchase RB, Chatham JC.

Am J Physiol Cell Physiol. 2006 Jan;290(1):C57-65. Epub 2005 Aug 17.


A store-operated nonselective cation channel in human lymphocytes.

Su Z, Guo X, Barker DS, Shoemaker RL, Marchase RB, Blalock JE.

Cell Mol Neurobiol. 2005 Jun;25(3-4):625-47.


Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils.

Kneass ZT, Marchase RB.

J Biol Chem. 2005 Apr 15;280(15):14579-85. Epub 2005 Feb 9.


Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc.

Kneass ZT, Marchase RB.

J Biol Chem. 2004 Oct 29;279(44):45759-65. Epub 2004 Aug 20.


Hexosamine pathway is responsible for inhibition by diabetes of phenylephrine-induced inotropy.

Pang Y, Bounelis P, Chatham JC, Marchase RB.

Diabetes. 2004 Apr;53(4):1074-81.


Adult rat cardiomyocytes exhibit capacitative calcium entry.

Hunton DL, Zou L, Pang Y, Marchase RB.

Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1124-32. Epub 2003 Nov 20.


Hyperglycemia inhibits capacitative calcium entry and hypertrophy in neonatal cardiomyocytes.

Pang Y, Hunton DL, Bounelis P, Marchase RB.

Diabetes. 2002 Dec;51(12):3461-7.


Regulation of Ca2+ release-activated Ca2+ channels by INAD and Ca2+ influx factor.

Su Z, Barker DS, Csutora P, Chang T, Shoemaker RL, Marchase RB, Blalock JE.

Am J Physiol Cell Physiol. 2003 Feb;284(2):C497-505. Epub 2002 Oct 16.


Calnexin is associated with and induced by overexpressed human complement protein C2.

Tsukamoto H, Tousson A, Circolo A, Marchase RB, Volanakis JE.

Anat Rec. 2002 May 1;267(1):7-16.


Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes.

Hunton DL, Lucchesi PA, Pang Y, Cheng X, Dell'Italia LJ, Marchase RB.

J Biol Chem. 2002 Apr 19;277(16):14266-73. Epub 2002 Feb 4.


A store-operated nonselective cation channel in lymphocytes is activated directly by Ca(2+) influx factor and diacylglycerol.

Su Z, Csutora P, Hunton D, Shoemaker RL, Marchase RB, Blalock JE.

Am J Physiol Cell Physiol. 2001 May;280(5):C1284-92.


Calcium influx factor directly activates store-operated cation channels in vascular smooth muscle cells.

Trepakova ES, Csutora P, Hunton DL, Marchase RB, Cohen RA, Bolotina VM.

J Biol Chem. 2000 Aug 25;275(34):26158-63.


Preparation and use of a photoactivatable glucose-6-phosphate analogue.

Peng J, Chen PY, Marchase RB, Prestwich GD.

Bioorg Med Chem Lett. 2000 Mar 20;10(6):535-9.


Measuring contributions to the research mission of medical schools.

Holmes EW, Burks TF, Dzau V, Hindery MA, Jones RF, Kaye CI, Korn D, Limbird LE, Marchase RB, Perlmutter R, Sanfilippo F, Strom BL.

Acad Med. 2000 Mar;75(3):303-13.


Loss of the major isoform of phosphoglucomutase results in altered calcium homeostasis in Saccharomyces cerevisiae.

Fu L, Miseta A, Hunton D, Marchase RB, Bedwell DM.

J Biol Chem. 2000 Feb 25;275(8):5431-40.


Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal.

Prince LS, Peter K, Hatton SR, Zaliauskiene L, Cotlin LF, Clancy JP, Marchase RB, Collawn JF.

J Biol Chem. 1999 Feb 5;274(6):3602-9.


Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores.

Csutora P, Su Z, Kim HY, Bugrim A, Cunningham KW, Nuccitelli R, Keizer JE, Hanley MR, Blalock JE, Marchase RB.

Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):121-6.


Glucose-6-phosphate and Ca2+ sequestration are mutually enhanced in microsomes from liver, brain, and heart.

Chen PY, Csutora P, Veyna-Burke NA, Marchase RB.

Diabetes. 1998 Jun;47(6):874-81.


Pathophysiology of diabetic complications.

Polak M, Newfield RS, Fioretto P, Czernichow P, Marchase R.

Diabetologia. 1997 Oct;40 Suppl 3:B65-7. No abstract available.


Epidemiology and genetics of diabetic complications.

Newfield RS, Polak M, Marchase R, Czernichow P.

Diabetologia. 1997 Oct;40 Suppl 3:B62-4. No abstract available.


Down-regulation of secretion of human complement component C2 by the product of an alternatively spliced C2 messenger RNA.

Tsukamoto H, Tousson A, Marchase RB, Volanakis JE.

J Immunol. 1996 Jun 15;156(12):4901-8.


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