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Items: 24


Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay.

Hammoud L, Adams JR, Loch AJ, Marcellus RC, Uehling DE, Aman A, Fladd C, McKee TD, Jo CEB, Al-Awar R, Egan SE, Rossant J.

Stem Cell Reports. 2016 Oct 11;7(4):787-801. doi: 10.1016/j.stemcr.2016.08.004. Epub 2016 Sep 8.


Interaction between the human mitochondrial import receptors Tom20 and Tom70 in vitro suggests a chaperone displacement mechanism.

Fan AC, Kozlov G, Hoegl A, Marcellus RC, Wong MJ, Gehring K, Young JC.

J Biol Chem. 2011 Sep 16;286(37):32208-19. doi: 10.1074/jbc.M111.280446. Epub 2011 Jul 19.


Genetic analysis of B55alpha/Cdc55 protein phosphatase 2A subunits: association with the adenovirus E4orf4 protein.

Zhang Z, Mui MZ, Chan F, Roopchand DE, Marcellus RC, Blanchette P, Li S, Berghuis AM, Branton PE.

J Virol. 2011 Jan;85(1):286-95. doi: 10.1128/JVI.01381-10. Epub 2010 Nov 3.


An RNA aptamer that selectively inhibits the enzymatic activity of protein tyrosine phosphatase 1B in vitro.

Townshend B, Aubry I, Marcellus RC, Gehring K, Tremblay ML.

Chembiochem. 2010 Jul 26;11(11):1583-93. doi: 10.1002/cbic.201000208.


Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis.

Nguyen M, Marcellus RC, Roulston A, Watson M, Serfass L, Murthy Madiraju SR, Goulet D, Viallet J, BĂ©lec L, Billot X, Acoca S, Purisima E, Wiegmans A, Cluse L, Johnstone RW, Beauparlant P, Shore GC.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19512-7. Epub 2007 Nov 26.


Proapoptotic BID is an ATM effector in the DNA-damage response.

Kamer I, Sarig R, Zaltsman Y, Niv H, Oberkovitz G, Regev L, Haimovich G, Lerenthal Y, Marcellus RC, Gross A.

Cell. 2005 Aug 26;122(4):593-603.


BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts.

Sarig R, Zaltsman Y, Marcellus RC, Flavell R, Mak TW, Gross A.

J Biol Chem. 2003 Mar 21;278(12):10707-15. Epub 2003 Jan 7. Erratum in: J Biol Chem. 2013 Apr 19;288(16):11503.


Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.

Mathai JP, Germain M, Marcellus RC, Shore GC.

Oncogene. 2002 Apr 11;21(16):2534-44.


Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A.

Marcellus RC, Chan H, Paquette D, Thirlwell S, Boivin D, Branton PE.

J Virol. 2000 Sep;74(17):7869-77.


Viruses and apoptosis.

Roulston A, Marcellus RC, Branton PE.

Annu Rev Microbiol. 1999;53:577-628. Review.


RBP1 induces growth arrest by repression of E2F-dependent transcription.

Lai A, Marcellus RC, Corbeil HB, Branton PE.

Oncogene. 1999 Mar 25;18(12):2091-100.


The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis.

Marcellus RC, Lavoie JN, Boivin D, Shore GC, Ketner G, Branton PE.

J Virol. 1998 Sep;72(9):7144-53.


E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk.

Lavoie JN, Nguyen M, Marcellus RC, Branton PE, Shore GC.

J Cell Biol. 1998 Feb 9;140(3):637-45.


Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.

Querido E, Marcellus RC, Lai A, Charbonneau R, Teodoro JG, Ketner G, Branton PE.

J Virol. 1997 May;71(5):3788-98.


Expression of p53 in Saos-2 osteosarcoma cells induces apoptosis which can be inhibited by Bcl-2 or the adenovirus E1B-55 kDa protein.

Marcellus RC, Teodoro JG, Charbonneau R, Shore GC, Branton PE.

Cell Growth Differ. 1996 Dec;7(12):1643-50.


Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis.

Marcellus RC, Teodoro JG, Wu T, Brough DE, Ketner G, Shore GC, Branton PE.

J Virol. 1996 Sep;70(9):6207-15.


Role of phosphorylation near the amino terminus of adenovirus type 5 early region 1A proteins.

Dumont DJ, Marcellus RC, Bayley ST, Branton PE.

J Gen Virol. 1993 Apr;74 ( Pt 4):583-95.


Quantitative analysis of regions of adenovirus E1A products involved in interactions with cellular proteins.

Barbeau D, Marcellus RC, Bacchetti S, Bayley ST, Branton PE.

Biochem Cell Biol. 1992 Oct-Nov;70(10-11):1123-34. Review.


Transforming signals generated by the polyoma virus tumor antigens.

Raptis L, Marcellus RC, Whitfield JF.

Adv Enzyme Regul. 1990;30:133-42. Review.


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