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Items: 1 to 50 of 177

1.

Deleterious Effects of Cold Air Inhalation on Coronary Physiological Indices in Patients With Obstructive Coronary Artery Disease.

Williams RP, Asrress KN, Lumley M, Arri S, Patterson T, Ellis H, Manou-Stathopoulou V, Macfarlane C, Chandran S, Moschonas K, Oakeshott P, Lockie T, Chiribiri A, Clapp B, Perera D, Plein S, Marber MS, Redwood SR.

J Am Heart Assoc. 2018 Jul 17;7(14):e008837. doi: 10.1161/JAHA.118.008837.

2.

The TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules.

De Nicola GF, Bassi R, Nichols C, Fernandez-Caggiano M, Golforoush PA, Thapa D, Anderson R, Martin ED, Verma S, Kleinjung J, Laing A, Hutchinson JP, Eaton P, Clark J, Marber MS.

JCI Insight. 2018 Aug 23;3(16). pii: 121144. doi: 10.1172/jci.insight.121144. eCollection 2018 Aug 23.

3.

Response by Asrress et al to Letter Regarding Article, "Physiology of Angina and Its Alleviation With Nitroglycerin: Insights From Invasive Catheter Laboratory Measurements During Exercise".

Asrress KN, Williams R, Lockie T, Khawaja MZ, Patterson T, Arri S, De Silva K, Perera D, Marber MS, Redwood SR.

Circulation. 2018 Feb 13;137(7):755-756. doi: 10.1161/CIRCULATIONAHA.117.031553. No abstract available.

PMID:
29440203
4.

Cardioprotection by an anti-MASP-2 antibody in a murine model of myocardial infarction.

Clark JE, Dudler T, Marber MS, Schwaeble W.

Open Heart. 2018 Jan 9;5(1):e000652. doi: 10.1136/openhrt-2017-000652. eCollection 2018.

5.

TAB1-Induced Autoactivation of p38α Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185.

Thapa D, Nichols C, Bassi R, Martin ED, Verma S, Conte MR, De Santis V, De Nicola GF, Marber MS.

Mol Cell Biol. 2018 Feb 12;38(5). pii: e00409-17. doi: 10.1128/MCB.00409-17. Print 2018 Mar 1.

6.

A single centre prospective cohort study addressing the effect of a rule-in/rule-out troponin algorithm on routine clinical practice.

Marjot J, Kaier TE, Henderson K, Hunter L, Marber MS, Perera D.

Eur Heart J Acute Cardiovasc Care. 2019 Aug;8(5):404-411. doi: 10.1177/2048872617746850. Epub 2017 Dec 4.

7.

Cardiac myosin-binding protein C is a novel marker of myocardial injury and fibrosis in aortic stenosis.

Anand A, Chin C, Shah ASV, Kwiecinski J, Vesey A, Cowell J, Weber E, Kaier T, Newby DE, Dweck M, Marber MS, Mills NL.

Heart. 2018 Jul;104(13):1101-1108. doi: 10.1136/heartjnl-2017-312257. Epub 2017 Dec 1.

8.

Contrast-enhanced magnetic resonance imaging for the detection of ruptured coronary plaques in patients with acute myocardial infarction.

Jansen CHP, Perera D, Wiethoff AJ, Phinikaridou A, Razavi RM, Rinaldi A, Marber MS, Greil GF, Nagel E, Maintz D, Redwood S, Botnar RM, Makowski MR.

PLoS One. 2017 Nov 30;12(11):e0188292. doi: 10.1371/journal.pone.0188292. eCollection 2017.

9.

Loss of Protein Kinase Novel 1 (PKN1) is associated with mild systolic and diastolic contractile dysfunction, increased phospholamban Thr17 phosphorylation, and exacerbated ischaemia-reperfusion injury.

Francois AA, Obasanjo-Blackshire K, Clark JE, Boguslavskyi A, Holt MR, Parker PJ, Marber MS, Heads RJ.

Cardiovasc Res. 2018 Jan 1;114(1):138-157. doi: 10.1093/cvr/cvx206.

10.

Cardiac troponins: from myocardial infarction to chronic disease.

Park KC, Gaze DC, Collinson PO, Marber MS.

Cardiovasc Res. 2017 Dec 1;113(14):1708-1718. doi: 10.1093/cvr/cvx183. Review.

11.

Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3.

Bassi R, Burgoyne JR, DeNicola GF, Rudyk O, DeSantis V, Charles RL, Eaton P, Marber MS.

J Biol Chem. 2017 Sep 29;292(39):16161-16173. doi: 10.1074/jbc.M117.785410. Epub 2017 Jul 24.

12.

Physiology of Angina and Its Alleviation With Nitroglycerin: Insights From Invasive Catheter Laboratory Measurements During Exercise.

Asrress KN, Williams R, Lockie T, Khawaja MZ, De Silva K, Lumley M, Patterson T, Arri S, Ihsan S, Ellis H, Guilcher A, Clapp B, Chowienczyk PJ, Plein S, Perera D, Marber MS, Redwood SR.

Circulation. 2017 Jul 4;136(1):24-34. doi: 10.1161/CIRCULATIONAHA.116.025856. Epub 2017 May 3.

13.

Quantifying the Release of Biomarkers of Myocardial Necrosis from Cardiac Myocytes and Intact Myocardium.

Marjot J, Kaier TE, Martin ED, Reji SS, Copeland O, Iqbal M, Goodson B, Hamren S, Harding SE, Marber MS.

Clin Chem. 2017 May;63(5):990-996. doi: 10.1373/clinchem.2016.264648. Epub 2017 Apr 4.

14.

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response.

Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamas K, Hadgraft N, Martin ED, Worthington J, Rudyk O, Rodriguez Cutillas P, Cuello F, Shattock MJ, Marber MS, Conte MR, Greenstein A, Greensmith DJ, Venetucci L, Timms JF, Eaton P.

Nat Commun. 2016 Oct 26;7:13187. doi: 10.1038/ncomms13187.

15.

From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research".

Cabrera-Fuentes HA, Aragones J, Bernhagen J, Boening A, Boisvert WA, Bøtker HE, Bulluck H, Cook S, Di Lisa F, Engel FB, Engelmann B, Ferrazzi F, Ferdinandy P, Fong A, Fleming I, Gnaiger E, Hernández-Reséndiz S, Kalkhoran SB, Kim MH, Lecour S, Liehn EA, Marber MS, Mayr M, Miura T, Ong SB, Peter K, Sedding D, Singh MK, Suleiman MS, Schnittler HJ, Schulz R, Shim W, Tello D, Vogel CW, Walker M, Li QO, Yellon DM, Hausenloy DJ, Preissner KT.

Basic Res Cardiol. 2016 Nov;111(6):69. Epub 2016 Oct 14. Review.

16.

Coronary Physiology During Exercise and Vasodilation in the Healthy Heart and in Severe Aortic Stenosis.

Lumley M, Williams R, Asrress KN, Arri S, Briceno N, Ellis H, Rajani R, Siebes M, Piek JJ, Clapp B, Redwood SR, Marber MS, Chambers JB, Perera D.

J Am Coll Cardiol. 2016 Aug 16;68(7):688-97. doi: 10.1016/j.jacc.2016.05.071.

17.

Mental stress-induced myocardial ischaemia.

Arri SS, Ryan M, Redwood SR, Marber MS.

Heart. 2016 Mar;102(6):472-80. doi: 10.1136/heartjnl-2014-307306. Epub 2016 Jan 4. Review. No abstract available.

PMID:
26729692
18.

The development and application of a high-sensitivity immunoassay for cardiac myosin-binding protein C.

Marjot J, Liebetrau C, Goodson RJ, Kaier T, Weber E, Heseltine P, Marber MS.

Transl Res. 2016 Apr;170:17-25.e5. doi: 10.1016/j.trsl.2015.11.008. Epub 2015 Dec 8.

19.

Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside.

Cabrera-Fuentes HA, Alba-Alba C, Aragones J, Bernhagen J, Boisvert WA, Bøtker HE, Cesarman-Maus G, Fleming I, Garcia-Dorado D, Lecour S, Liehn E, Marber MS, Marina N, Mayr M, Perez-Mendez O, Miura T, Ruiz-Meana M, Salinas-Estefanon EM, Ong SB, Schnittler HJ, Sanchez-Vega JT, Sumoza-Toledo A, Vogel CW, Yarullina D, Yellon DM, Preissner KT, Hausenloy DJ.

Basic Res Cardiol. 2016 Jan;111(1):7. doi: 10.1007/s00395-015-0527-0. Epub 2015 Dec 14.

20.

Gadd45γ regulates cardiomyocyte death and post-myocardial infarction left ventricular remodelling.

Lucas A, Mialet-Perez J, Daviaud D, Parini A, Marber MS, Sicard P.

Cardiovasc Res. 2015 Nov 1;108(2):254-67. doi: 10.1093/cvr/cvv219. Epub 2015 Sep 14.

PMID:
26370247
21.

Design and rationale for the randomised, double-blinded, placebo-controlled Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS) crossover study.

Myat A, Arri S, Bhatt DL, Gersh BJ, Redwood SR, Marber MS.

Cardiovasc Diabetol. 2015 Feb 19;14:27. doi: 10.1186/s12933-015-0193-4.

22.

Cardiac myosin-binding protein C: a potential early biomarker of myocardial injury.

Baker JO, Tyther R, Liebetrau C, Clark J, Howarth R, Patterson T, Möllmann H, Nef H, Sicard P, Kailey B, Devaraj R, Redwood SR, Kunst G, Weber E, Marber MS.

Basic Res Cardiol. 2015 May;110(3):23. doi: 10.1007/s00395-015-0478-5. Epub 2015 Apr 3.

23.

Pro-protein convertase subtilisin/kexin 9 concentrations correlate with coronary artery disease atheroma burden in a Pakistani cohort with chronic chest pain.

Walton TA, Nishtar S, Lumb PJ, Crook MA, Marber MS, Gill J, Wierzbicki AS.

Int J Clin Pract. 2015 Jul;69(7):738-42. doi: 10.1111/ijcp.12615. Epub 2015 Feb 24.

PMID:
25707773
24.

The effects of cold and exercise on the cardiovascular system.

Manou-Stathopoulou V, Goodwin CD, Patterson T, Redwood SR, Marber MS, Williams RP.

Heart. 2015 May 15;101(10):808-20. doi: 10.1136/heartjnl-2014-306276. Epub 2015 Feb 11. Review. No abstract available.

PMID:
25673528
25.

Republished: 'Warm-Up Angina': harnessing the benefits of exercise and myocardial ischaemia.

Williams RP, Manou-Stathopoulou V, Redwood SR, Marber MS.

Postgrad Med J. 2014 Nov;90(1069):648-56. doi: 10.1136/postgradmedj-2013-304187rep. Review.

PMID:
25335796
26.

Angiographic coronary artery disease and high-sensitivity troponin-T in a native Pakistani cohort presenting with chronic chest pain.

Walton TA, Nishtar S, Lumb PJ, Crook MA, Marber MS, Gill J, Wierzbicki AS.

Int J Clin Pract. 2014 Dec;68(12):1473-7. doi: 10.1111/ijcp.12520. Epub 2014 Oct 6.

PMID:
25283732
27.

p38 MAPK in cardioprotection - are we there yet?

Martin ED, Bassi R, Marber MS.

Br J Pharmacol. 2015 Apr;172(8):2101-13. doi: 10.1111/bph.12901. Epub 2014 Nov 24. Review.

28.

Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial.

Newby LK, Marber MS, Melloni C, Sarov-Blat L, Aberle LH, Aylward PE, Cai G, de Winter RJ, Hamm CW, Heitner JF, Kim R, Lerman A, Patel MR, Tanguay JF, Lepore JJ, Al-Khalidi HR, Sprecher DL, Granger CB; SOLSTICE Investigators.

Lancet. 2014 Sep 27;384(9949):1187-95. doi: 10.1016/S0140-6736(14)60417-7. Epub 2014 Jun 12. Erratum in: Lancet. 2014 Sep 27;384(9949):1186.

PMID:
24930728
29.

In vivo assessment of aortic aneurysm wall integrity using elastin-specific molecular magnetic resonance imaging.

Botnar RM, Wiethoff AJ, Ebersberger U, Lacerda S, Blume U, Warley A, Jansen CH, Onthank DC, Cesati RR, Razavi R, Marber MS, Hamm B, Schaeffter T, Robinson SP, Makowski MR.

Circ Cardiovasc Imaging. 2014 Jul;7(4):679-89. doi: 10.1161/CIRCIMAGING.113.001131. Epub 2014 May 28.

PMID:
24871347
30.

Diabetes, incretin hormones and cardioprotection.

Myat A, Redwood SR, Gersh BJ, Yellon DM, Marber MS.

Heart. 2014 Oct;100(19):1550-61. doi: 10.1136/heartjnl-2012-303242. Epub 2014 Apr 19. No abstract available.

PMID:
24747994
31.

Protein kinase Cε-calcineurin cosignaling downstream of toll-like receptor 4 downregulates fibrosis and induces wound healing gene expression in cardiac myofibroblasts.

Mesquita RF, Paul MA, Valmaseda A, Francois A, Jabr R, Anjum S, Marber MS, Budhram-Mahadeo V, Heads RJ.

Mol Cell Biol. 2014 Feb;34(4):574-94. doi: 10.1128/MCB.01098-13. Epub 2013 Dec 2.

32.

Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1.

DeNicola GF, Martin ED, Chaikuad A, Bassi R, Clark J, Martino L, Verma S, Sicard P, Tata R, Atkinson RA, Knapp S, Conte MR, Marber MS.

Nat Struct Mol Biol. 2013 Oct;20(10):1182-90. doi: 10.1038/nsmb.2668. Epub 2013 Sep 15.

33.

Future treatment strategies in ST-segment elevation myocardial infarction.

Windecker S, Bax JJ, Myat A, Stone GW, Marber MS.

Lancet. 2013 Aug 17;382(9892):644-57. doi: 10.1016/S0140-6736(13)61452-X. Review.

PMID:
23953388
34.

'Warm-up Angina': harnessing the benefits of exercise and myocardial ischaemia.

Williams RP, Manou-Stathopoulou V, Redwood SR, Marber MS.

Heart. 2014 Jan;100(2):106-14. doi: 10.1136/heartjnl-2013-304187. Epub 2013 Jun 18. Review.

PMID:
23781112
35.

The study of LoSmapimod treatment on inflammation and InfarCtSizE (SOLSTICE): design and rationale.

Melloni C, Sprecher DL, Sarov-Blat L, Patel MR, Heitner JF, Hamm CW, Aylward P, Tanguay JF, DeWinter RJ, Marber MS, Lerman A, Hasselblad V, Granger CB, Newby LK.

Am Heart J. 2012 Nov;164(5):646-653.e3. doi: 10.1016/j.ahj.2012.07.030. Epub 2012 Oct 16.

PMID:
23137494
36.

Synergistic adaptations to exercise in the systemic and coronary circulations that underlie the warm-up angina phenomenon.

Lockie TP, Rolandi MC, Guilcher A, Perera D, De Silva K, Williams R, Asrress KN, Patel K, Plein S, Chowienczyk P, Siebes M, Redwood SR, Marber MS.

Circulation. 2012 Nov 27;126(22):2565-74. doi: 10.1161/CIRCULATIONAHA.112.094292. Epub 2012 Nov 1.

PMID:
23124033
37.

Advancements in pressure-volume catheter technology - stress remodelling after infarction.

Clark JE, Marber MS.

Exp Physiol. 2013 Mar;98(3):614-21. doi: 10.1113/expphysiol.2012.064733. Epub 2012 Oct 12. Review.

38.

Design and rationale of the MR-INFORM study: stress perfusion cardiovascular magnetic resonance imaging to guide the management of patients with stable coronary artery disease.

Hussain ST, Paul M, Plein S, McCann GP, Shah AM, Marber MS, Chiribiri A, Morton G, Redwood S, MacCarthy P, Schuster A, Ishida M, Westwood MA, Perera D, Nagel E.

J Cardiovasc Magn Reson. 2012 Sep 19;14:65. doi: 10.1186/1532-429X-14-65.

39.

Effects of p38 mitogen-activated protein kinase inhibition on vascular and systemic inflammation in patients with atherosclerosis.

Elkhawad M, Rudd JH, Sarov-Blat L, Cai G, Wells R, Davies LC, Collier DJ, Marber MS, Choudhury RP, Fayad ZA, Tawakol A, Gleeson FV, Lepore JJ, Davis B, Willette RN, Wilkinson IB, Sprecher DL, Cheriyan J.

JACC Cardiovasc Imaging. 2012 Sep;5(9):911-22. doi: 10.1016/j.jcmg.2012.02.016.

40.

Remote ischaemic preconditioning in coronary artery bypass surgery: a meta-analysis.

D'Ascenzo F, Cavallero E, Moretti C, Omedè P, Sciuto F, Rahman IA, Bonser RS, Yunseok J, Wagner R, Freiberger T, Kunst G, Marber MS, Thielmann M, Ji B, Amr YM, Modena MG, Zoccai GB, Sheiban I, Gaita F.

Heart. 2012 Sep;98(17):1267-71. doi: 10.1136/heartjnl-2011-301551. Review.

PMID:
22875822
41.

New therapeutic targets in cardiology: p38 alpha mitogen-activated protein kinase for ischemic heart disease.

Denise Martin E, De Nicola GF, Marber MS.

Circulation. 2012 Jul 17;126(3):357-68. doi: 10.1161/CIRCULATIONAHA.111.071886. Review. No abstract available.

PMID:
22801653
42.

Heartbreak ridge: multimodality imaging of an apical intramural hematoma.

Bajwa SK, Rajani R, Child N, Marber MS, Chiribiri A, Wright MJ.

Int J Cardiol. 2013 Feb 10;163(1):e4-6. doi: 10.1016/j.ijcard.2012.06.109. Epub 2012 Jul 15. No abstract available.

PMID:
22800619
43.

Ruptured aneurysm of the sinus of valsalva insights from magnetic resonance first-pass myocardial perfusion imaging.

Schuster A, Hedström E, Blauth C, Marber MS, Nagel E, Carr-White G.

J Am Coll Cardiol. 2012 Jan 31;59(5):538. doi: 10.1016/j.jacc.2011.04.053. No abstract available.

44.

Detection of intracoronary thrombus by magnetic resonance imaging in patients with acute myocardial infarction.

Jansen CH, Perera D, Makowski MR, Wiethoff AJ, Phinikaridou A, Razavi RM, Marber MS, Greil GF, Nagel E, Maintz D, Redwood S, Botnar RM.

Circulation. 2011 Jul 26;124(4):416-24. doi: 10.1161/CIRCULATIONAHA.110.965442. Epub 2011 Jul 11.

PMID:
21747055
45.

Collateral formation in the absence of obstructive coronary artery disease: potential new pathways in cardioprotection.

Asrress KN, Redwood SR, Marber MS.

Cardiology. 2011;118(3):195-7. doi: 10.1159/000328653. Epub 2011 Jun 22. No abstract available.

PMID:
21701168
46.

Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation?

Karuppasamy P, Chaubey S, Dew T, Musto R, Sherwood R, Desai J, John L, Shah AM, Marber MS, Kunst G.

Basic Res Cardiol. 2011 Jun;106(4):511-9. doi: 10.1007/s00395-011-0185-9. Epub 2011 May 5.

PMID:
21544683
47.

Limitations of the MRL mouse as a model for cardiac regeneration.

Moseley FL, Faircloth ME, Lockwood W, Marber MS, Bicknell KA, Valasek P, Brooks G.

J Pharm Pharmacol. 2011 May;63(5):648-56. doi: 10.1111/j.2042-7158.2011.01261.x.

PMID:
21492166
48.

Will o' the WISP1: a novel mediator of Ang-II induced cardiomyocyte hypertrophy.

Martin ED, Marber MS.

J Mol Cell Cardiol. 2011 Jun;50(6):925-7. doi: 10.1016/j.yjmcc.2011.03.006. Epub 2011 Apr 1. No abstract available.

PMID:
21439967
49.

Assessment of atherosclerotic plaque burden with an elastin-specific magnetic resonance contrast agent.

Makowski MR, Wiethoff AJ, Blume U, Cuello F, Warley A, Jansen CH, Nagel E, Razavi R, Onthank DC, Cesati RR, Marber MS, Schaeffter T, Smith A, Robinson SP, Botnar RM.

Nat Med. 2011 Mar;17(3):383-8. doi: 10.1038/nm.2310. Epub 2011 Feb 20.

PMID:
21336283
50.

Developing small molecules to inhibit kinases unkind to the heart: p38 MAPK as a case in point.

Marber MS, Molkentin JD, Force T.

Drug Discov Today Dis Mech. 2010 Summer;7(2):e123-e127.

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