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Items: 1 to 50 of 143

1.

Mutations in Influenza A Virus Neuraminidase and Hemagglutinin Confer Resistance against a Broadly Neutralizing Hemagglutinin Stem Antibody.

Prachanronarong KL, Canale AS, Liu P, Somasundaran M, Hou S, Poh YP, Han T, Zhu Q, Renzette N, Zeldovich KB, Kowalik TF, Kurt-Yilmaz N, Jensen JD, Bolon DNA, Marasco WA, Finberg RW, Schiffer CA, Wang JP.

J Virol. 2019 Jan 4;93(2). pii: e01639-18. doi: 10.1128/JVI.01639-18. Print 2019 Jan 15.

2.

Alcohol consumption increase susceptibility to pneumococcal pneumonia in a humanized murine HIV model mediated by intestinal dysbiosis.

Samuelson DR, Siggins RW, Ruan S, Amedee AM, Sun J, Zhu QK, Marasco WA, Taylor CM, Luo M, Welsh DA, Shellito JE.

Alcohol. 2018 Sep 10. pii: S0741-8329(18)30166-6. doi: 10.1016/j.alcohol.2018.08.012. [Epub ahead of print]

PMID:
30213614
3.

Synonymous Mutations at the Beginning of the Influenza A Virus Hemagglutinin Gene Impact Experimental Fitness.

Canale AS, Venev SV, Whitfield TW, Caffrey DR, Marasco WA, Schiffer CA, Kowalik TF, Jensen JD, Finberg RW, Zeldovich KB, Wang JP, Bolon DNA.

J Mol Biol. 2018 Apr 13;430(8):1098-1115. doi: 10.1016/j.jmb.2018.02.009. Epub 2018 Feb 18.

PMID:
29466705
4.

The latest animal models of ovarian cancer for novel drug discovery.

Magnotti E, Marasco WA.

Expert Opin Drug Discov. 2018 Mar;13(3):249-257. doi: 10.1080/17460441.2018.1426567. Epub 2018 Jan 17. Review.

5.

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope.

Avnir Y, Prachanronarong KL, Zhang Z, Hou S, Peterson EC, Sui J, Zayed H, Kurella VB, McGuire AT, Stamatatos L, Hilbert BJ, Bohn MF, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Goodall M, Jefferis R, Zhu Q, Kurt Yilmaz N, Schiffer CA, Marasco WA.

Cell Rep. 2017 Dec 12;21(11):3243-3255. doi: 10.1016/j.celrep.2017.11.056.

6.

Immunocapture isotope dilution mass spectrometry in response to a pandemic influenza threat.

Pierce CL, Williams TL, Santana WI, Levine M, Chen LM, Cooper HC, Solano MI, Woolfitt AR, Marasco WA, Fang H, Donis RO, Barr JR.

Vaccine. 2017 Sep 5;35(37):5011-5018. doi: 10.1016/j.vaccine.2017.07.049. Epub 2017 Jul 31.

7.

The Individual and Population Genetics of Antibody Immunity.

Watson CT, Glanville J, Marasco WA.

Trends Immunol. 2017 Jul;38(7):459-470. doi: 10.1016/j.it.2017.04.003. Epub 2017 May 20. Review.

8.

A mouse model for MERS coronavirus-induced acute respiratory distress syndrome.

Cockrell AS, Yount BL, Scobey T, Jensen K, Douglas M, Beall A, Tang XC, Marasco WA, Heise MT, Baric RS.

Nat Microbiol. 2016 Nov 28;2:16226. doi: 10.1038/nmicrobiol.2016.226.

9.

Antibody Prophylaxis Against Dengue Virus 2 Infection in Non-Human Primates.

Simmons M, Putnak R, Sun P, Burgess T, Marasco WA.

Am J Trop Med Hyg. 2016 Nov 2;95(5):1148-1156. Epub 2016 Sep 19.

10.

A broadly neutralizing anti-influenza antibody reveals ongoing capacity of haemagglutinin-specific memory B cells to evolve.

Fu Y, Zhang Z, Sheehan J, Avnir Y, Ridenour C, Sachnik T, Sun J, Hossain MJ, Chen LM, Zhu Q, Donis RO, Marasco WA.

Nat Commun. 2016 Sep 13;7:12780. doi: 10.1038/ncomms12780.

11.

Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model.

Suarez ER, Chang de K, Sun J, Sui J, Freeman GJ, Signoretti S, Zhu Q, Marasco WA.

Oncotarget. 2016 Jun 7;7(23):34341-55. doi: 10.18632/oncotarget.9114.

12.

Anti-CCR4 monoclonal antibody enhances antitumor immunity by modulating tumor-infiltrating Tregs in an ovarian cancer xenograft humanized mouse model.

Chang DK, Peterson E, Sun J, Goudie C, Drapkin RI, Liu JF, Matulonis U, Zhu Q, Marasco WA.

Oncoimmunology. 2015 Dec 10;5(3):e1090075. eCollection 2016 Mar.

13.

Erratum: IGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicity.

Avnir Y, Watson CT, Glanville J, Peterson EC, Tallarico AS, Bennett AS, Qin K, Fu Y, Huang CY, Beigel JH, Breden F, Zhu Q, Marasco WA.

Sci Rep. 2016 Apr 29;6:23876. doi: 10.1038/srep23876. No abstract available.

14.

Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.

Menachery VD, Yount BL Jr, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS.

Nat Med. 2016 Apr;22(4):446. doi: 10.1038/nm0416-446d. No abstract available.

PMID:
27050591
15.

SARS-like WIV1-CoV poised for human emergence.

Menachery VD, Yount BL Jr, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, Lanzavecchia A, Marasco WA, Baric RS.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3048-53. doi: 10.1073/pnas.1517719113. Epub 2016 Mar 14.

16.

Humanized mouse G6 anti-idiotypic monoclonal antibody has therapeutic potential against IGHV1-69 germline gene-based B-CLL.

Chang DK, Kurella VB, Biswas S, Avnir Y, Sui J, Wang X, Sun J, Wang Y, Panditrao M, Peterson E, Tallarico A, Fernandes S, Goodall M, Zhu Q, Brown JR, Jefferis R, Marasco WA.

MAbs. 2016 May-Jun;8(4):787-98. doi: 10.1080/19420862.2016.1159365. Epub 2016 Mar 10.

17.

IGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicity.

Avnir Y, Watson CT, Glanville J, Peterson EC, Tallarico AS, Bennett AS, Qin K, Fu Y, Huang CY, Beigel JH, Breden F, Zhu Q, Marasco WA.

Sci Rep. 2016 Feb 16;6:20842. doi: 10.1038/srep20842. Erratum in: Sci Rep. 2016 Apr 29;6:23876.

18.

3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012.

Johnson RF, Bagci U, Keith L, Tang X, Mollura DJ, Zeitlin L, Qin J, Huzella L, Bartos CJ, Bohorova N, Bohorov O, Goodman C, Kim DH, Paulty MH, Velasco J, Whaley KJ, Johnson JC, Pettitt J, Ork BL, Solomon J, Oberlander N, Zhu Q, Sun J, Holbrook MR, Olinger GG, Baric RS, Hensley LE, Jahrling PB, Marasco WA.

Virology. 2016 Mar;490:49-58. doi: 10.1016/j.virol.2016.01.004. Epub 2016 Jan 30.

19.

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.

Menachery VD, Yount BL Jr, Debbink K, Agnihothram S, Gralinski LE, Plante JA, Graham RL, Scobey T, Ge XY, Donaldson EF, Randell SH, Lanzavecchia A, Marasco WA, Shi ZL, Baric RS.

Nat Med. 2015 Dec;21(12):1508-13. doi: 10.1038/nm.3985. Epub 2015 Nov 9. Erratum in: Nat Med. 2016 Apr;22(4):446.

20.

Reconstitution of the receptor-binding motif of the SARS coronavirus.

Freund NT, Roitburd-Berman A, Sui J, Marasco WA, Gershoni JM.

Protein Eng Des Sel. 2015 Dec;28(12):567-75. doi: 10.1093/protein/gzv052. Epub 2015 Oct 20.

PMID:
26487711
21.

Phage and Yeast Display.

Sheehan J, Marasco WA.

Microbiol Spectr. 2015 Feb;3(1):AID-0028-2014. doi: 10.1128/microbiolspec.AID-0028-2014. Review.

PMID:
26104550
22.

Human neutralizing antibodies against MERS coronavirus: implications for future immunotherapy.

Tang XC, Marasco WA.

Immunotherapy. 2015;7(6):591-4. doi: 10.2217/imt.15.33. Epub 2015 Jun 22. No abstract available.

23.

Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo.

Chang DK, Moniz RJ, Xu Z, Sun J, Signoretti S, Zhu Q, Marasco WA.

Mol Cancer. 2015 Jun 11;14:119. doi: 10.1186/s12943-015-0384-3.

24.

Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme.

Huang X, Dong W, Milewska A, Golda A, Qi Y, Zhu QK, Marasco WA, Baric RS, Sims AC, Pyrc K, Li W, Sui J.

J Virol. 2015 Jul;89(14):7202-13. doi: 10.1128/JVI.00854-15. Epub 2015 Apr 29.

25.

Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3.

Goettel JA, Biswas S, Lexmond WS, Yeste A, Passerini L, Patel B, Yang S, Sun J, Ouahed J, Shouval DS, McCann KJ, Horwitz BH, Mathis D, Milford EL, Notarangelo LD, Roncarolo MG, Fiebiger E, Marasco WA, Bacchetta R, Quintana FJ, Pai SY, Klein C, Muise AM, Snapper SB.

Blood. 2015 Jun 18;125(25):3886-95. doi: 10.1182/blood-2014-12-618363. Epub 2015 Apr 1.

26.

Anti-tat Hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages.

Kang W, Marasco WA, Tong HI, Byron MM, Wu C, Shi Y, Sun S, Sun Y, Lu Y.

J Neuroinflammation. 2014 Nov 22;11:195. doi: 10.1186/s12974-014-0195-2.

27.

Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness.

Sui J, Deming M, Rockx B, Liddington RC, Zhu QK, Baric RS, Marasco WA.

J Virol. 2014 Dec;88(23):13769-80. doi: 10.1128/JVI.02232-14. Epub 2014 Sep 17.

28.

Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaque lower genital tract by AAV gene transfer.

Abdel-Motal UM, Harbison C, Han T, Pudney J, Anderson DJ, Zhu Q, Westmoreland S, Marasco WA.

Gene Ther. 2014 Sep;21(9):802-10. doi: 10.1038/gt.2014.56. Epub 2014 Jun 26.

29.

Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses.

Avnir Y, Tallarico AS, Zhu Q, Bennett AS, Connelly G, Sheehan J, Sui J, Fahmy A, Huang CY, Cadwell G, Bankston LA, McGuire AT, Stamatatos L, Wagner G, Liddington RC, Marasco WA.

PLoS Pathog. 2014 May 1;10(5):e1004103. doi: 10.1371/journal.ppat.1004103. eCollection 2014 May.

30.

Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution.

Tang XC, Agnihothram SS, Jiao Y, Stanhope J, Graham RL, Peterson EC, Avnir Y, Tallarico AS, Sheehan J, Zhu Q, Baric RS, Marasco WA.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):E2018-26. doi: 10.1073/pnas.1402074111. Epub 2014 Apr 28.

31.

Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.

Almagro JC, Gilliland GL, Breden F, Scott JK, Sok D, Pauthner M, Reichert JM, Helguera G, Andrabi R, Mabry R, Bléry M, Voss JE, Laurén J, Abuqayyas L, Barghorn S, Ben-Jacob E, Crowe JE Jr, Huston JS, Johnston SA, Krauland E, Lund-Johansen F, Marasco WA, Parren PW, Xu KY.

MAbs. 2014 May-Jun;6(3):577-618. doi: 10.4161/mabs.28421. Epub 2014 Mar 3.

32.

Regression of established renal cell carcinoma in nude mice using lentivirus-transduced human T cells expressing a human anti-CAIX chimeric antigen receptor.

Lo AS, Xu C, Murakami A, Marasco WA.

Mol Ther Oncolytics. 2014 Dec 10;1:14003. doi: 10.1038/mto.2014.3. eCollection 2014.

33.

Identification and isolation of small CD44-negative mesenchymal stem/progenitor cells from human bone marrow using elutriation and polychromatic flow cytometry.

Hall SR, Jiang Y, Leary E, Yavanian G, Eminli S, O'Neill DW, Marasco WA.

Stem Cells Transl Med. 2013 Aug;2(8):567-78. doi: 10.5966/sctm.2012-0155. Epub 2013 Jul 11.

34.

Identification of inhibitory scFv antibodies targeting fibroblast activation protein utilizing phage display functional screens.

Zhang J, Valianou M, Simmons H, Robinson MK, Lee HO, Mullins SR, Marasco WA, Adams GP, Weiner LM, Cheng JD.

FASEB J. 2013 Feb;27(2):581-9. doi: 10.1096/fj.12-210377. Epub 2012 Oct 26.

35.

Human anti-CCR4 minibody gene transfer for the treatment of cutaneous T-cell lymphoma.

Han T, Abdel-Motal UM, Chang DK, Sui J, Muvaffak A, Campbell J, Zhu Q, Kupper TS, Marasco WA.

PLoS One. 2012;7(9):e44455. doi: 10.1371/journal.pone.0044455. Epub 2012 Sep 4.

36.

Fatal fulminant hepatic failure from adenovirus in allogeneic bone marrow transplant patients.

Vyas JM, Marasco WA.

Case Rep Infect Dis. 2012;2012:463569. doi: 10.1155/2012/463569. Epub 2012 Aug 15.

37.

Humanization of an anti-CCR4 antibody that kills cutaneous T-cell lymphoma cells and abrogates suppression by T-regulatory cells.

Chang DK, Sui J, Geng S, Muvaffak A, Bai M, Fuhlbrigge RC, Lo A, Yammanuru A, Hubbard L, Sheehan J, Campbell JJ, Zhu Q, Kupper TS, Marasco WA.

Mol Cancer Ther. 2012 Nov;11(11):2451-61. doi: 10.1158/1535-7163.MCT-12-0278. Epub 2012 Aug 6.

38.

Respiratory virus detection in immunocompromised patients with FilmArray respiratory panel compared to conventional methods.

Hammond SP, Gagne LS, Stock SR, Marty FM, Gelman RS, Marasco WA, Poritz MA, Baden LR.

J Clin Microbiol. 2012 Oct;50(10):3216-21. doi: 10.1128/JCM.00538-12. Epub 2012 Jul 18.

39.

In vivo selection of CD4(+) T cells transduced with a gamma-retroviral vector expressing a single-chain intrabody targeting HIV-1 tat.

Braun SE, Taube R, Zhu Q, Wong FE, Murakami A, Kamau E, Dwyer M, Qiu G, Daigle J, Carville A, Johnson RP, Marasco WA.

Hum Gene Ther. 2012 Sep;23(9):917-31. doi: 10.1089/hum.2011.184.

40.

Human B-cell ontogeny in humanized NOD/SCID γc(null) mice generates a diverse yet auto/poly- and HIV-1-reactive antibody repertoire.

Chang H, Biswas S, Tallarico AS, Sarkis PT, Geng S, Panditrao MM, Zhu Q, Marasco WA.

Genes Immun. 2012 Jul;13(5):399-410. doi: 10.1038/gene.2012.16. Epub 2012 May 17.

41.

Humoral immune responses in humanized BLT mice immunized with West Nile virus and HIV-1 envelope proteins are largely mediated via human CD5+ B cells.

Biswas S, Chang H, Sarkis PT, Fikrig E, Zhu Q, Marasco WA.

Immunology. 2011 Dec;134(4):419-33. doi: 10.1111/j.1365-2567.2011.03501.x. Erratum in: Immunology. 2012 Jul;136(3):361.

42.

Anti-gp120 minibody gene transfer to female genital epithelial cells protects against HIV-1 virus challenge in vitro.

Abdel-Motal UM, Sarkis PT, Han T, Pudney J, Anderson DJ, Zhu Q, Marasco WA.

PLoS One. 2011;6(10):e26473. doi: 10.1371/journal.pone.0026473. Epub 2011 Oct 21.

43.

Fine epitope mapping of monoclonal antibodies against hemagglutinin of a highly pathogenic H5N1 influenza virus using yeast surface display.

Han T, Sui J, Bennett AS, Liddington RC, Donis RO, Zhu Q, Marasco WA.

Biochem Biophys Res Commun. 2011 Jun 3;409(2):253-9. doi: 10.1016/j.bbrc.2011.04.139. Epub 2011 May 5.

44.

Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies.

Sui J, Sheehan J, Hwang WC, Bankston LA, Burchett SK, Huang CY, Liddington RC, Beigel JH, Marasco WA.

Clin Infect Dis. 2011 Apr 15;52(8):1003-9. doi: 10.1093/cid/cir121.

45.

Structural basis of influenza virus neutralization.

Han T, Marasco WA.

Ann N Y Acad Sci. 2011 Jan;1217:178-90. doi: 10.1111/j.1749-6632.2010.05829.x. Epub 2011 Jan 11. Review.

46.

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection.

Wrammert J, Koutsonanos D, Li GM, Edupuganti S, Sui J, Morrissey M, McCausland M, Skountzou I, Hornig M, Lipkin WI, Mehta A, Razavi B, Del Rio C, Zheng NY, Lee JH, Huang M, Ali Z, Kaur K, Andrews S, Amara RR, Wang Y, Das SR, O'Donnell CD, Yewdell JW, Subbarao K, Marasco WA, Mulligan MJ, Compans R, Ahmed R, Wilson PC.

J Exp Med. 2011 Jan 17;208(1):181-93. doi: 10.1084/jem.20101352. Epub 2011 Jan 10. Erratum in: J Exp Med. 2011 Feb 14;208(2):411.

47.

Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus.

Hashem AM, Van Domselaar G, Li C, Wang J, She YM, Cyr TD, Sui J, He R, Marasco WA, Li X.

Biochem Biophys Res Commun. 2010 Dec 10;403(2):247-51. doi: 10.1016/j.bbrc.2010.11.030. Epub 2010 Nov 13.

PMID:
21078301
48.

Antibodies and lentiviruses that specifically recognize a T cell epitope derived from HIV-1 Nef protein and presented by HLA-C.

Herschhorn A, Marasco WA, Hizi A.

J Immunol. 2010 Dec 15;185(12):7623-32. doi: 10.4049/jimmunol.1001561. Epub 2010 Nov 12.

49.

Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology.

Xu C, Lo A, Yammanuru A, Tallarico AS, Brady K, Murakami A, Barteneva N, Zhu Q, Marasco WA.

PLoS One. 2010 Mar 10;5(3):e9625. doi: 10.1371/journal.pone.0009625.

50.

Recombinant single-chain variable fragment antibodies against extracellular epitopes of human multidrug resistance protein MRP3 for targeting malignant gliomas.

Kuan CT, Srivastava N, McLendon RE, Marasco WA, Zalutsky MR, Bigner DD.

Int J Cancer. 2010 Aug 1;127(3):598-611. doi: 10.1002/ijc.25062.

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