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Items: 44


Dopamine D2-like receptor stimulation blocks negative feedback in visual and spatial reversal learning in the rat: behavioural and computational evidence.

Alsiö J, Phillips BU, Sala-Bayo J, Nilsson SRO, Calafat-Pla TC, Rizwand A, Plumbridge JM, López-Cruz L, Dalley JW, Cardinal RN, Mar AC, Robbins TW.

Psychopharmacology (Berl). 2019 Aug;236(8):2307-2323. doi: 10.1007/s00213-019-05296-y. Epub 2019 Jun 19.


Continuous performance test impairment in a 22q11.2 microdeletion mouse model: improvement by amphetamine.

Nilsson SRO, Heath CJ, Takillah S, Didienne S, Fejgin K, Nielsen V, Nielsen J, Saksida LM, Mariani J, Faure P, Didriksen M, Robbins TW, Bussey TJ, Mar AC.

Transl Psychiatry. 2018 Nov 14;8(1):247. doi: 10.1038/s41398-018-0295-3.


Effects of anterior cingulate cortex lesions on a continuous performance task for mice.

Hvoslef-Eide M, Nilsson SR, Hailwood JM, Robbins TW, Saksida LM, Mar AC, Bussey TJ.

Brain Neurosci Adv. 2018 Jan;2. doi: 10.1177/2398212818772962. Epub 2018 May 29.


The anterior insula bidirectionally modulates cost-benefit decision-making on a rodent gambling task.

Daniel ML, Cocker PJ, Lacoste J, Mar AC, Houeto JL, Belin-Rauscent A, Belin D.

Eur J Neurosci. 2017 Nov;46(10):2620-2628. doi: 10.1111/ejn.13689. Epub 2017 Oct 6.


MAM-E17 rat model impairments on a novel continuous performance task: effects of potential cognitive enhancing drugs.

Mar AC, Nilsson SRO, Gamallo-Lana B, Lei M, Dourado T, Alsiö J, Saksida LM, Bussey TJ, Robbins TW.

Psychopharmacology (Berl). 2017 Oct;234(19):2837-2857. doi: 10.1007/s00213-017-4679-5. Epub 2017 Jul 26.


Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma.

Wu MM, Li CF, Lin LF, Wang AS, Pu YS, Wang HH, Mar AC, Chen CJ, Lee TC.

Oncotarget. 2017 Apr 4;8(14):23787-23802. doi: 10.18632/oncotarget.15865.


Erratum to: The continuous performance test (rCPT) for mice: a novel operant touchscreen test of attentional function.

Kim CH, Hvoslef-Eide M, Nilsson SR, Johnson MR, Herbert BR, Robbins TW, Saksida LM, Bussey TJ, Mar AC.

Psychopharmacology (Berl). 2016 Sep;233(18):3471. No abstract available.


Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis.

Su JC, Mar AC, Wu SH, Tai WT, Chu PY, Wu CY, Tseng LM, Lee TC, Chen KF, Liu CY, Chiu HC, Shiau CW.

Sci Rep. 2016 Jul 1;6:28888. doi: 10.1038/srep28888.


Blocking TNF-α inhibits angiogenesis and growth of IFIT2-depleted metastatic oral squamous cell carcinoma cells.

Lai KC, Liu CJ, Lin TJ, Mar AC, Wang HH, Chen CW, Hong ZX, Lee TC.

Cancer Lett. 2016 Jan 28;370(2):207-15. doi: 10.1016/j.canlet.2015.10.016. Epub 2015 Oct 27.


The continuous performance test (rCPT) for mice: a novel operant touchscreen test of attentional function.

Kim CH, Hvoslef-Eide M, Nilsson SR, Johnson MR, Herbert BR, Robbins TW, Saksida LM, Bussey TJ, Mar AC.

Psychopharmacology (Berl). 2015 Nov;232(21-22):3947-66. doi: 10.1007/s00213-015-4081-0. Epub 2015 Sep 29. Erratum in: Psychopharmacology (Berl). 2016 Sep;233(18):3471.


A novel 2- and 3-choice touchscreen-based continuous trial-unique nonmatching-to-location task (cTUNL) sensitive to functional differences between dentate gyrus and CA3 subregions of the hippocampus.

Oomen CA, Hvoslef-Eide M, Kofink D, Preusser F, Mar AC, Saksida LM, Bussey TJ.

Psychopharmacology (Berl). 2015 Nov;232(21-22):3921-3933. doi: 10.1007/s00213-015-4019-6. Epub 2015 Jul 30.


Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis.

Mar AC, Chu CH, Lee HJ, Chien CW, Cheng JJ, Yang SH, Jiang JK, Lee TC.

J Biol Chem. 2015 Sep 4;290(36):22212-24. doi: 10.1074/jbc.M115.644823. Epub 2015 Jul 24.


The NEWMEDS rodent touchscreen test battery for cognition relevant to schizophrenia.

Hvoslef-Eide M, Mar AC, Nilsson SR, Alsiö J, Heath CJ, Saksida LM, Robbins TW, Bussey TJ.

Psychopharmacology (Berl). 2015 Nov;232(21-22):3853-72. doi: 10.1007/s00213-015-4007-x. Epub 2015 Jul 24. Review.


Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia.

McAllister KA, Mar AC, Theobald DE, Saksida LM, Bussey TJ.

Psychopharmacology (Berl). 2015 Nov;232(21-22):3883-97. doi: 10.1007/s00213-015-4018-7. Epub 2015 Jul 21.


Trial-unique, delayed nonmatching-to-location (TUNL) touchscreen testing for mice: sensitivity to dorsal hippocampal dysfunction.

Kim CH, Romberg C, Hvoslef-Eide M, Oomen CA, Mar AC, Heath CJ, Berthiaume AA, Bussey TJ, Saksida LM.

Psychopharmacology (Berl). 2015 Nov;232(21-22):3935-45. doi: 10.1007/s00213-015-4017-8. Epub 2015 Jul 15.


The role of 5-HT2C receptors in touchscreen visual reversal learning in the rat: a cross-site study.

Alsiö J, Nilsson SR, Gastambide F, Wang RA, Dam SA, Mar AC, Tricklebank M, Robbins TW.

Psychopharmacology (Berl). 2015 Nov;232(21-22):4017-31. doi: 10.1007/s00213-015-3963-5. Epub 2015 May 26.


Avoidance behavior: a free-operant lever-press avoidance task for the assessment of the effects of safety signals.

Fernando ABP, Mar AC, Urcelay GP, Dickinson A, Robbins TW.

Curr Protoc Neurosci. 2015 Jan 5;70:8.32.1-8.32.12. doi: 10.1002/0471142301.ns0832s70.


Impaired limbic cortico-striatal structure and sustained visual attention in a rodent model of schizophrenia.

Barnes SA, Sawiak SJ, Caprioli D, Jupp B, Buonincontri G, Mar AC, Harte MK, Fletcher PC, Robbins TW, Neill JC, Dalley JW.

Int J Neuropsychopharmacol. 2014 Oct 31;18(2). pii: pyu010. doi: 10.1093/ijnp/pyu010.


Safety signals as instrumental reinforcers during free-operant avoidance.

Fernando AB, Urcelay GP, Mar AC, Dickinson A, Robbins TW.

Learn Mem. 2014 Aug 18;21(9):488-97. doi: 10.1101/lm.034603.114. Print 2014 Sep.


High locomotor reactivity to novelty is associated with an increased propensity to choose saccharin over cocaine: new insights into the vulnerability to addiction.

Vanhille N, Belin-Rauscent A, Mar AC, Ducret E, Belin D.

Neuropsychopharmacology. 2015 Feb;40(3):577-89. doi: 10.1038/npp.2014.204. Epub 2014 Aug 14.


The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD.

Eagle DM, Noschang C, d'Angelo LS, Noble CA, Day JO, Dongelmans ML, Theobald DE, Mar AC, Urcelay GP, Morein-Zamir S, Robbins TW.

Behav Brain Res. 2014 May 1;264:207-29. doi: 10.1016/j.bbr.2013.12.040. Epub 2014 Jan 6.


The role of the nucleus accumbens shell in the mediation of the reinforcing properties of a safety signal in free-operant avoidance: dopamine-dependent inhibitory effects of d-amphetamine.

Fernando AB, Urcelay GP, Mar AC, Dickinson TA, Robbins TW.

Neuropsychopharmacology. 2014 May;39(6):1420-30. doi: 10.1038/npp.2013.337. Epub 2013 Dec 12.


Activation of postsynaptic 5-HT1A receptors improve stress adaptation.

Zhou J, Cao X, Mar AC, Ding YQ, Wang X, Li Q, Li L.

Psychopharmacology (Berl). 2014 May;231(10):2067-75. doi: 10.1007/s00213-013-3350-z. Epub 2013 Nov 21.


Atomoxetine decreases vulnerability to develop compulsivity in high impulsive rats.

Ansquer S, Belin-Rauscent A, Dugast E, Duran T, Benatru I, Mar AC, Houeto JL, Belin D.

Biol Psychiatry. 2014 May 15;75(10):825-32. doi: 10.1016/j.biopsych.2013.09.031. Epub 2013 Oct 11.


The touchscreen operant platform for testing working memory and pattern separation in rats and mice.

Oomen CA, Hvoslef-Eide M, Heath CJ, Mar AC, Horner AE, Bussey TJ, Saksida LM.

Nat Protoc. 2013 Oct;8(10):2006-21. doi: 10.1038/nprot.2013.124. Epub 2013 Sep 19.


The touchscreen operant platform for assessing executive function in rats and mice.

Mar AC, Horner AE, Nilsson SR, Alsiö J, Kent BA, Kim CH, Holmes A, Saksida LM, Bussey TJ.

Nat Protoc. 2013 Oct;8(10):1985-2005. doi: 10.1038/nprot.2013.123. Epub 2013 Sep 19.


Measuring reinforcement learning and motivation constructs in experimental animals: relevance to the negative symptoms of schizophrenia.

Markou A, Salamone JD, Bussey TJ, Mar AC, Brunner D, Gilmour G, Balsam P.

Neurosci Biobehav Rev. 2013 Nov;37(9 Pt B):2149-65. doi: 10.1016/j.neubiorev.2013.08.007. Epub 2013 Aug 28. Review.


Divergent effects of D₂/₃ receptor activation in the nucleus accumbens core and shell on impulsivity and locomotor activity in high and low impulsive rats.

Moreno M, Economidou D, Mar AC, López-Granero C, Caprioli D, Theobald DE, Fernando A, Newman AH, Robbins TW, Dalley JW.

Psychopharmacology (Berl). 2013 Jul;228(1):19-30. doi: 10.1007/s00213-013-3010-3. Epub 2013 Feb 14.


Comparison of the conditioned reinforcing properties of a safety signal and appetitive stimulus: effects of d-amphetamine and anxiolytics.

Fernando AB, Urcelay GP, Mar AC, Dickinson A, Robbins TW.

Psychopharmacology (Berl). 2013 May;227(2):195-208. doi: 10.1007/s00213-012-2952-1. Epub 2013 Jan 9.


High anxiety is a predisposing endophenotype for loss of control over cocaine, but not heroin, self-administration in rats.

Dilleen R, Pelloux Y, Mar AC, Molander A, Robbins TW, Everitt BJ, Dalley JW, Belin D.

Psychopharmacology (Berl). 2012 Jul;222(1):89-97. doi: 10.1007/s00213-011-2626-4. Epub 2012 Jan 14.


Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex.

Murphy ER, Fernando AB, Urcelay GP, Robinson ES, Mar AC, Theobald DE, Dalley JW, Robbins TW.

Psychopharmacology (Berl). 2012 Jan;219(2):401-10. doi: 10.1007/s00213-011-2572-1. Epub 2011 Nov 19.


Prefrontal and monoaminergic contributions to stop-signal task performance in rats.

Bari A, Mar AC, Theobald DE, Elands SA, Oganya KC, Eagle DM, Robbins TW.

J Neurosci. 2011 Jun 22;31(25):9254-63. doi: 10.1523/JNEUROSCI.1543-11.2011.


Contrasting roles for dopamine D1 and D2 receptor subtypes in the dorsomedial striatum but not the nucleus accumbens core during behavioral inhibition in the stop-signal task in rats.

Eagle DM, Wong JC, Allan ME, Mar AC, Theobald DE, Robbins TW.

J Neurosci. 2011 May 18;31(20):7349-56. doi: 10.1523/JNEUROSCI.6182-10.2011.


New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats.

Bussey TJ, Holmes A, Lyon L, Mar AC, McAllister KA, Nithianantharajah J, Oomen CA, Saksida LM.

Neuropharmacology. 2012 Mar;62(3):1191-203. doi: 10.1016/j.neuropharm.2011.04.011. Epub 2011 Apr 21. Review.


Dissociable effects of lesions to orbitofrontal cortex subregions on impulsive choice in the rat.

Mar AC, Walker AL, Theobald DE, Eagle DM, Robbins TW.

J Neurosci. 2011 Apr 27;31(17):6398-404. doi: 10.1523/JNEUROSCI.6620-10.2011.


Serotonin modulates sensitivity to reward and negative feedback in a probabilistic reversal learning task in rats.

Bari A, Theobald DE, Caprioli D, Mar AC, Aidoo-Micah A, Dalley JW, Robbins TW.

Neuropsychopharmacology. 2010 May;35(6):1290-301. doi: 10.1038/npp.2009.233. Epub 2010 Jan 27.


The rat prelimbic cortex mediates inhibitory response control but not the consolidation of instrumental learning.

Jonkman S, Mar AC, Dickinson A, Robbins TW, Everitt BJ.

Behav Neurosci. 2009 Aug;123(4):875-85. doi: 10.1037/a0016330.


A new touchscreen test of pattern separation: effect of hippocampal lesions.

McTighe SM, Mar AC, Romberg C, Bussey TJ, Saksida LM.

Neuroreport. 2009 Jun 17;20(9):881-5. doi: 10.1097/WNR.0b013e32832c5eb2.


Dissociable effects of noradrenaline, dopamine, and serotonin uptake blockade on stop task performance in rats.

Bari A, Eagle DM, Mar AC, Robinson ES, Robbins TW.

Psychopharmacology (Berl). 2009 Aug;205(2):273-83. doi: 10.1007/s00213-009-1537-0. Epub 2009 Apr 30.


Behavioural characterisation of high impulsivity on the 5-choice serial reaction time task: specific deficits in 'waiting' versus 'stopping'.

Robinson ES, Eagle DM, Economidou D, Theobald DE, Mar AC, Murphy ER, Robbins TW, Dalley JW.

Behav Brain Res. 2009 Jan 23;196(2):310-6. doi: 10.1016/j.bbr.2008.09.021. Epub 2008 Oct 2.


High impulsivity predicts the switch to compulsive cocaine-taking.

Belin D, Mar AC, Dalley JW, Robbins TW, Everitt BJ.

Science. 2008 Jun 6;320(5881):1352-5. doi: 10.1126/science.1158136.


Delay discounting and impulsive choice in the rat.

Mar AC, Robbins TW.

Curr Protoc Neurosci. 2007 Apr;Chapter 8:Unit 8.22. doi: 10.1002/0471142301.ns0822s39.


Neurobehavioral mechanisms of impulsivity: fronto-striatal systems and functional neurochemistry.

Dalley JW, Mar AC, Economidou D, Robbins TW.

Pharmacol Biochem Behav. 2008 Aug;90(2):250-60. doi: 10.1016/j.pbb.2007.12.021. Epub 2007 Dec 27. Review.


Similar effects of the selective noradrenaline reuptake inhibitor atomoxetine on three distinct forms of impulsivity in the rat.

Robinson ES, Eagle DM, Mar AC, Bari A, Banerjee G, Jiang X, Dalley JW, Robbins TW.

Neuropsychopharmacology. 2008 Apr;33(5):1028-37. Epub 2007 Jul 18.

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